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Elsevier

Woodhead Publishing

  • Polymers and Nanomaterials for Gene Therapy

    • 1st Edition
    • Ravin Narain
    • English
    Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy. The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy. This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.

  • Advances in Chemical Mechanical Planarization (CMP)

    • 1st Edition
    • Babu Suryadevara
    • English
    Advances in Chemical Mechanical Planarization (CMP) provides the latest information on a mainstream process that is critical for high-volume, high-yield semiconductor manufacturing, and even more so as device dimensions continue to shrink. The technology has grown to encompass the removal and planarization of multiple metal and dielectric materials and layers both at the device and the metallization levels, using different tools and parameters, requiring improvements in the control of topography and defects. This important book offers a systematic review of fundamentals and advances in the area. Part One covers CMP of dielectric and metal films, with chapters focusing on the use of particular techniques and processes, and on CMP of particular various materials, including ultra low-k materials and high-mobility channel materials, and ending with a chapter reviewing the environmental impacts of CMP processes. Part Two addresses consumables and process control for improved CMP, and includes chapters on the preparation and characterization of slurry, diamond disc pad conditioning, the use of FTIR spectroscopy for characterization of surface processes, and approaches for defection characterization, mitigation, and reduction.

  • Fundamentals and Applications of Nanophotonics

    • 1st Edition
    • Joseph W. Haus
    • English
    Fundamentals and Applications of Nanophotonics includes a comprehensive discussion of the field of nanophotonics, including key enabling technologies that have the potential to drive economic growth and impact numerous application domains such as ICT, the environment, healthcare, military, transport, manufacturing, and energy. This book gives readers the theoretical underpinnings needed to understand the latest advances in the field. After an introduction to the area, chapters two and three cover the essential topics of electrodynamics, quantum mechanics, and computation as they relate to nanophotonics. Subsequent chapters explore materials for nanophotonics, including nanoparticles, photonic crystals, nanosilicon, nanocarbon, III-V, and II-VI semiconductors. In addition, fabrication and characterization techniques are addressed, along with the importance of plasmonics, and the applications of nanophotonics in devices such as lasers, LEDs, and photodetectors.

  • Fuel Flexible Energy Generation

    Solid, Liquid and Gaseous Fuels
    • 1st Edition
    • John Oakey
    • English
    Fuel Flexible Energy Generation: Solid, Liquid and Gaseous Fuels provides updated information on flexible fuel energy generation, the process by which one or more fuels can be combusted in the same boiler or turbine to generate power. By adapting or building boilers and turbines to accept multiple fuel sources, they can be co-fired with biomass and waste derived fuels, allowing a reduction in carbon output, thus providing cleaner energy. Fuel flexibility is becoming more important in a world of diminishing fossil fuel stocks. Many countries are investing in the development of more efficient fuel flexible boilers and turbines, and their use is becoming more prevalent in industry as well. This book provides comprehensive coverage of flexible fuel energy generation across all potential fuel types, and was written by a selection of experts in the field who discuss the types of fuels which can be used in fuel flexible energy generation, from solid fuels to biomass fuels, the preparation of fuels to be used in fuel flexible operations, that includes their handling and transport, and combustion and conversion technologies with chapters ranging from large-scale coal gasification to technology options and plant design issues.

  • CAPA in the Pharmaceutical and Biotech Industries

    How to Implement an Effective Nine Step Program
    • 1st Edition
    • J Rodriguez
    • English
    CAPA in the Pharmaceutical and Biotech Industries: How to Implement an Effective Nine Step Program contains the most current information on how to implement, develop, and maintain an effective Corrective Action and Preventive Action (CAPA) and investigation program using a nine step closed-loop process approach for medical devices and pharmaceutical and biologic manufacturers, as well as any anyone who has to maintain a quality system.This book addresses how companies often make the mistake of fixing problems in their processes by revising procedures or, more commonly, by retraining employees that may or may not have caused the problem. This event-focused fix leads to the false assumption that the errors have been eradicated and will be prevented in the future. The reality is that the causes of the failure were never actually determined, therefore the same problem will recur over and over. CAPA is a complete system that collects information regarding existing and potential quality problems. It analyzes and investigates the issues to identify the root cause of nonconformities. It is not just a quick-fix, simple approach, it is a process and has to be understood throughout organizations.

  • Advances in Smart Medical Textiles

    Treatments and Health Monitoring
    • 1st Edition
    • Lieva van Langenhove
    • English
    Advances in Smart Medical Textiles: Treatments and Health Monitoring provides comprehensive coverage on smart textiles, the emerging and important materials that are finding applications in the fields of medicine and healthcare. The book explores the range of smart textiles available for use in medicine and the transfer of these innovative technologies into medical applications. Early chapters survey various smart fibers, fabrics, and finishes, while subsequent sections focus on the role of smart textiles in treating patients, from wound care to rehabilitation, and the use of textile-based sensors and wearable electronics for monitoring patient health.

  • Handbook of Technical Textiles

    Technical Textile Processes
    • 2nd Edition
    • A. Richard Horrocks + 1 more
    • English
    The second edition of Handbook of Technical Textiles, Volume 1: Technical Textile Processes provides readers with a comprehensive understanding of the latest advancements in technical textiles. With revised and updated coverage, including several new chapters, this volume reviews recent developments and technologies in the field, beginning with an overview of the technical textiles industry that includes coverage of technical fibers and yarns, weaving, spinning, knitting, and nonwoven production. Subsequent sections include discussions on finishing, coating, and the coloration of technical textiles.

  • Geometry with Trigonometry

    • 2nd Edition
    • Patrick D Barry
    • English
    Geometry with Trigonometry Second Edition is a second course in plane Euclidean geometry, second in the sense that many of its basic concepts will have been dealt with at school, less precisely. It gets underway with a large section of pure geometry in Chapters 2 to 5 inclusive, in which many familiar results are efficiently proved, although the logical frame work is not traditional. In Chapter 6 there is a convenient introduction of coordinate geometry in which the only use of angles is to handle the perpendicularity or parallelism of lines. Cartesian equations and parametric equations of a line are developed and there are several applications. In Chapter 7 basic properties of circles are developed, the mid-line of an angle-support, and sensed distances. In the short Chaper 8 there is a treatment of translations, axial symmetries and more generally isometries. In Chapter 9 trigonometry is dealt with in an original way which e.g. allows concepts such as clockwise and anticlockwise to be handled in a way which is not purely visual. By the stage of Chapter 9 we have a context in which calculus can be developed. In Chapter 10 the use of complex numbers as coordinates is introduced and the great conveniences this notation allows are systematically exploited. Many and varied topics are dealt with , including sensed angles, sensed area of a triangle, angles between lines as opposed to angles between co-initial half-lines (duo-angles). In Chapter 11 various convenient methods of proving geometrical results are established, position vectors, areal coordinates, an original concept mobile coordinates. In Chapter 12 trigonometric functions in the context of calculus are treated. New to this edition: The second edition has been comprehensively revised over three years Errors have been corrected and some proofs marginally improved The substantial difference is that Chapter 11 has been significantly extended, particularly the role of mobile coordinates, and a more thorough account of the material is given

  • Corrosion Under Insulation (CUI) Guidelines

    Revised
    • 2nd Edition
    • Volume 55
    • English
    Corrosion-under-insu... (CUI) refers to the external corrosion of piping and vessels that occurs underneath externally clad/jacketed insulation as a result of the penetration of water. By its very nature CUI tends to remain undetected until the insulation and cladding/jacketing is removed to allow inspection or when leaks occur. CUI is a common problem shared by the refining, petrochemical, power, industrial, onshore and offshore industries. In the first edition of this book published in 2008, the EFC Working Parties WP13 and WP15 engaged together to provide guidelines on managing CUI with contributions from a number of European refining, petrochemical and offshore companies. The guidelines are intended for use on all plants and installation that contain insulated vessels, piping and equipment. The guidelines cover a risk-based inspection methodology for CUI, inspection techniques and recommended best practice for mitigating CUI, including design of plant and equipment, coatings and the use of thermal spray techniques, types of insulation, cladding/jacketing materials and protection guards. The guidelines also include case studies. The original document first published in 2008 was very successful and provided an important resource in the continuing battle to mitigate CUI. Many members of the EFC corrosion community requested an update and this has taken between 18-24 months to do so. Hopefully this revised document will continue to serve the community providing a practical source of information on how to monitor and manage insulated systems.

  • Biosynthetic Polymers for Medical Applications

    • 1st Edition
    • Laura Poole-Warren + 2 more
    • English
    Biosynthetic Polymers for Medical Applications provides the latest information on biopolymers, the polymers that have been produced from living organisms and are biodegradable in nature. These advanced materials are becoming increasingly important for medical applications due to their favorable properties, such as degradability and biocompatibility. This important book provides readers with a thorough review of the fundamentals of biosynthetic polymers and their applications. Part One covers the fundamentals of biosynthetic polymers for medical applications, while Part Two explores biosynthetic polymer coatings and surface modification. Subsequent sections discuss biosynthetic polymers for tissue engineering applications and how to conduct polymers for medical applications.

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