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Elsevier

Elsevier Science

  • Cellular Organelles and the Extracellular Matrix

    • 1st Edition
    • Volume 3
    • Edward Bittar
    • English
    This volume is in two parts. The first contains the remaining chapters on cellular organelles and several chapters relating to organelle disorders. An account of mitochondriopathis is given in the chapter on the mitochondrion rather than in a separate one. The subject matter of this part of the volume shows quite clearly that the interdisciplinary approach to the study of organelles has shed considerable light on the nature of the mechanisms underlying the etiology and pathobiology of many of these disorders. As an example, mutations in the genes encoding integral membrane proteins are found to lead to disturbances in peroxisome assembly. It is also interesting and significant that mistargeting of protein is now thought to be another cause. It will be revealing to see whether mistargeting is the result of mutations in the genes encoding chaperones.The second part of the volume is concerned with the extracellular matrix. It sets out to show that a vast body of new knowledge of the extracellular matrix is available to us. Take for example the integrin family of cell adhesion receptors. It turns out that integrins play a key role not only in adhesion but also in coupling signals to the nucleus via the cytoskeleton. As for fibronectins, they seem to link the matrix with the cytoskeleton by interacting with integrins.Collagen molecules are dealt with in the last two chapters. The boundaries of collagen in disease are defined by drawing a clear line of demarcation between systemic connective tissue disorders (e.g., scleroderma), better known as autoimmune diseases, and the heritable, and the heritable diseases such as osteogenesis imperfect and the Marfan syndrome. This classification takes into account a second group of acquired disorders of collagen forming tissues in which regional fibrosis is the hallmark. Liver cirrhosis and pulmonary fibrosis are prime examples.The decision to place Volumes 2 and 3 before those dealing with cell chemistry was not easily made. It was based on the view that most students will have had an undergraduate course in biochemistry of cell biology or both courses, and that they could go to Volumes 4-7 in which the subject of cell chemistry is covered, and then return to Volumes 2 and 3.

  • Leak-Free Pumps and Compressors Handbook

    • 1st Edition
    • G. Vetter
    • English
    As environmental legislation concerning leaks and emissions tightens this practical reference manual is a must for all those involved with systems using leak-free (or seal-less) pumps or compressors. This handbook will enable you to understand the various designs and properties of leak-free pumps and select the right pump or compressor to ensure leak free systems whatever the application.

  • Structure, Fluctuation, and Relaxation in Solutions

    • 1st Edition
    • Volume 83
    • H. Nomura + 2 more
    • English
    The results of a special research project carried out for "Molecular Approaches to Non-equilibrium Process in Solution" were presented during The 42nd Yamada Conference on "Structure, Fluctuation and Relaxation in Solution" which was held from 11-15 December, 1994. The following topics were discussed at the conference:1. Solvation Dynamics 2. Relaxation, Fluctuation and Reaction Dynamics 3. Dynamic Structure and Reaction Mechanisms in Solutions. These topics were the main concern of this conference.

  • Handbook of Industrial Membranes

    • 2nd Edition
    • K. Scott
    • English
    This manual contains necessary and useful information and data in an easily accessible format relating to the use of membranes. Membranes are among the most important engineering components in use today, and each year more and more effective uses for membrane technologies are found - for example: water purification, industrial effluent treatment, solvent dehydration by per-vaporation, recovery of volatile organic compounds, protein recovery, bioseparations and many others.The pace of change in the membrane industry has been accelerating rapidly in recent years, occasioned in part by the demand of end-users, but also as a result of the investment in R&D by manufacturers. To reflect these changes the author has obtained the latest information from some of the leading suppliers in the business. In one complete volume this unique handbook gives practical guidance to using selected membrane processes in individual industries while also providing a useful guide to equipment selection and usage.

  • Petroleum Exploration and Exploitation in Norway

    • 1st Edition
    • Volume 4
    • S. Hanslien
    • English
    This conference was arranged by the Norwegian Petroleum Society in order to commemorate the first 25 years of exploration on the Norwegian Continental Shelf. Sixty papers and posters were presented of which 25 have been selected for this volume.Since the start of exploration activities during the mid 1960's the North Sea has not only proved to be one of the main petroleum provinces in the world, but has also established itself as an excellent laboratory for geoscientific research and application. This development has been stimulated greatly by the openess towards exchange of technical data encouragement by the Norwegian authorities.The objective of this book is to assess the results of 25 years of exploration in Norway. It focuses on lessons learned from past experiences as well as considering future challenges facing geoscientists in the industry (relating to both exploration and exploitation activities). Included, are papers which assess the status and future trends of exploration in the main geological provinces on the Norwegian Continental Shelf from the Central Graben in the south to Svalbard and the Russian Artic in the north.

  • Finite Element Methods (Part 2), Numerical Methods for Solids (Part 2)

    • 1st Edition
    • Volume 4
    • P.G. Ciarlet
    • English
    This series of volumes aims to cover all the major aspects of numerical analysis, serving as the basic reference work on the subject. Each volume will concentrate on one, two or three particular topics. Each article, written by an expert, is an in-depth survey, reflecting the most recent trends in the field, and is essentially self-contained. The Handbook will cover the basic methods of numerical analysis, under the following general headings: solution of equations in Rn; finite difference methods; finite element methods; techniques of scientific computing; and optimization theory and systems science. It will also cover the numerical solution of actual problems of contemporary interest in applied mathematics, under the following headings: numerical methods of fluids; numerical methods for solids; and specific applications - including meteorology, seismology, petroleum mechanics and celestial mechanics.

  • Current Neurochemical and Pharmacological Aspects of Biogenic Amines

    Their Function, Oxidative Deamination and Inhibition
    • 1st Edition
    • Volume 106
    • P.M. Yu + 2 more
    • English
    This book contains anonymous-peer-revie... invited contributions from the 6th Amine Oxidase Workshop and the 5th Trace Amine Conference. New developments in both basic and applied studies related to monoamine oxidases (MAO), semicarbazide-sensit... amine oxidase (SSAO) and the trace amines are addressed.

  • Pump Users Handbook

    • 4th Edition
    • R. Rayner
    • English
    This handbook places emphasis on the importance of correct interpretation of pumping requirements, both by the user and the supplier. Completely reworked to incorporate the very latest in pumping technology, this practical handbook will enable you to understand the principles of pumping, hydraulics and fluids and define the various criteria necessary for pump and ancillary selection. The Pump Users Handbook will prove an invaluable aid in ordering pump equipment and in the recognition of fundamental oprational problems.

  • Metallurgical and Materials Applications of Shock-Wave and High-Strain-Rate Phenomena

    • 1st Edition
    • L.E. Murr + 2 more
    • English
    The proceedings of EXPLOMETâ„¢ '95, International Conference on Metallurgical and Materials Applications of Shock-Wave and High-Strain-Rate Phenomena in Materials, was the fourth in the EXPLOMETâ„¢ quinquennial series begun in 1980. In the period since the last conference in 1990, significant world events have played a major role in the emphasis of topic areas. Shock consolidation continues to be an actively pursued research topic, but industrial applications have eluded it. Nonetheless, the pervasive theme of applications of shock wave and related high-strain-rate phenomena in a wide range of materials systems and processes remained a principal feature of this conference. Divided into eight sections, the book contains a total of 110 papers. Section I deals with dynamic consolidation of materials, while Section II covers dynamic fracture phenomena. Materials aspects of ballistic and hypervelocity impact and penetration are described in Section III, followed by a related treatment of extreme plastic deformation, including adiabatic shear bands, dynamic recrystallization, shaped charges, and explosively formed penetrator phenomena in Section IV. Modeling and simulation of shock-wave and high-strain-rate phenomena in materials is treated in Section V followed by shock-induced reactions and synthesis in Section VI, and shock wave modification materials structure and properties in Section VII. The final section (VIII) includes papers dealing generally with explosive welding, high-strain-rate deformation, and material working. This book, with emphasis on materials applications and effects, will provide a useful research update in the metallurgical materials applications of shock-wave and high-strain-rate phenomena, as well as a general reference tool and teaching component for specialized curricular dealing with dynamic effects in materials.

  • Cellular Organelles

    • 1st Edition
    • Volume 2
    • Edward Bittar
    • English
    The purpose of this volume is to provide a synopsis of present knowledge of the structure, organisation, and function of cellular organelles with an emphasis on the examination of important but unsolved problems, and the directions in which molecular and cell biology are moving. Though designed primarily to meet the needs of the first-year medical student, particularly in schools where the traditional curriculum has been partly or wholly replaced by a multi-disciplinary core curriculum, the mass of information made available here should prove useful to students of biochemistry, physiology, biology, bioengineering, dentistry, and nursing.It is not yet possible to give a complete account of the relations between the organelles of two compartments and of the mechanisms by which some degree of order is maintained in the cell as a whole. However, a new breed of scientists, known as molecular cell biologists, have already contributed in some measure to our understanding of several biological phenomena notably interorganelle communication. Take, for example, intracellular membrane transport: it can now be expressed in terms of the sorting, targeting, and transport of protein from the endoplasmic reticulum to another compartment. This volume contains the first ten chapters on the subject of organelles. The remaining four are in Volume 3, to which sections on organelle disorders and the extracellular matrix have been added.

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