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Elsevier

Elsevier Science

  • Cancer Metastasis: Experimental Approaches

    • 1st Edition
    • Volume 29
    • D. Rusciano + 1 more
    • D.R. Welch
    • English
    The book describes most of the methods that are currently used in metastasis research. Both in vivo and in vitro protocols are illustrated, so that the metastatic process can be either analysed as a whole, or single events addressed separately. Each method is described in the frame of the metastatic process, therefore its significance and its limitations in the context of metastasis are always taken into account. Whenever possible, several alternative procedures are reported per each experimental issue, so that the researcher can choose the one that better suits her/his needs and possibilities.During the past 30 years a big effort has been made to elucidate the molecular mechanisms of cancer metastatis, the leading cause of death for cancer patients. A considerable number of assays have been set up, that can be used to address specific questions concerning the single metastatic steps, or can be applied to develop and test drugs specifically interfering with selected events during the metastatic spread. This book contains an exhaustive description of most of the methods and their rationale, that are currently used in metastatic research, both to analyse metastasis in its entirety (in vivo models), or to dissect the single steps of the metastatic process (in vitro assays).

  • Lake Baikal

    A Mirror in Time and Space for Understanding Global Change Processes
    • 1st Edition
    • K. Minoura
    • English
    Lake Baikal is the oldest lake and largest freshwater reservoir in the world. As a result of its exceptionally long geological history, the lake has been a theatre of evolution and speciation of organisms, and it currently harbors more species than any other lake in the world. Based on its unique nature, Lake Baikal was recently designated a World Heritage site and is regarded as a hotspot for evolution, speciation, and biodiversity. With its tremendously peculiar biota, Lake Baikal is now awaiting modern analytical approaches to the profound problems of speciation and evolution. In late autumn 1998 a symposium was held in Japan with the theme "Lake Baikal: A mirror in time and space for understanding global change processes" to bring together scientists from different disciplines who are studying Lake Baikal. Three international scientific associations: The BICER (Baikal International Center for Ecological Research), BDP (Baikal Drilling Project), and DIWPA (Diversitas Western Pacific and Asia) were involved in the organisation.This book contains a selection of papers presented at this symposium. They are interdisciplinary in nature and bring together results from geology, paleontology, chemistry, biology, limnology and physics.

  • Muddy Coast Dynamics and Resource Management

    • 1st Edition
    • Volume 2
    • B.W. Flemming + 2 more
    • English
    Muddy coasts are land-sea transitional environments commonly found along low-energy shorelines which either receive large annual supplies of muddy sediments, or where unconsolidated muddy deposits are being eroded by wave action.In providing 21 case studies in different parts of the world this book provides an up-to-date review of the state of the art in muddy coast research. Issues dealing with hydrodynamics and suspended matter transport, erosion, deposition, and sediment budgets on tidal flats, primary production, nutrient fluxes and mineralization in lagoons are treated in a multi disciplinary manner. Most articles deal with issues which are of relevance with respect to global warming and future sea level rise.

  • Statistics for Petroleum Engineers and Geoscientists

    • 1st Edition
    • Volume 2
    • Jerry Jensen + 3 more
    • English
    Geostatistics is a common tool in reservoir characterization. Written from the basics of statistics, this book covers only those topics that are needed for the two goals of the text: to exhibit the diagnostic potential of statistics and to introduce the important features of statistical modelling. This revised edition contains expanded discussions of some materials, in particular conditional probabilities, Bayes Theorem, correlation, and Kriging. The coverage of estimation, variability, and modelling applications have been updated. Seventy examples illustrate concepts and show the role of geology for providing important information for data analysis and model building. Four reservoir case studies conclude the presentation, illustrating the application and importance of the earlier material. This book aims to help petroleum professionals develop more accurate models, leading to lower sampling costs. It is an ideal book for petroleum engineers, geoscientists, hydrologists, and faculty and students in these and related fields.

  • III-Nitride Semiconductors

    Electrical, Structural and Defects Properties
    • 1st Edition
    • M.O. Manasreh
    • English
    Research advances in III-nitride semiconductor materials and device have led to an exponential increase in activity directed towards electronic and optoelectronic applications. There is also great scientific interest in this class of materials because they appear to form the first semiconductor system in which extended defects do not severely affect the optical properties of devices. The volume consists of chapters written by a number of leading researchers in nitride materials and device technology with the emphasis on the dopants incorporations, impurities identifications, defects engineering, defects characterization, ion implantation, irradiation-induced defects, residual stress, structural defects and phonon confinement. This unique volume provides a comprehensive review and introduction of defects and structural properties of GaN and related compounds for newcomers to the field and stimulus to further advances for experienced researchers. Given the current level of interest and research activity directed towards nitride materials and devices, the publication of the volume is particularly timely. Early pioneering work by Pankove and co-workers in the 1970s yielded a metal-insulator-semi... GaN light-emitting diode (LED), but the difficulty of producing p-type GaN precluded much further effort. The current level of activity in nitride semiconductors was inspired largely by the results of Akasaki and co-workers and of Nakamura and co-workers in the late 1980s and early 1990s in the development of p-type doping in GaN and the demonstration of nitride-based LEDs at visible wavelengths. These advances were followed by the successful fabrication and commercialization of nitride blue laser diodes by Nakamura et al at Nichia. The chapters contained in this volume constitutes a mere sampling of the broad range of research on nitride semiconductor materials and defect issues currently being pursued in academic, government, and industrial laboratories worldwide.

  • Gallium Arsenide, Electronics Materials and Devices. A Strategic Study of Markets, Technologies and Companies Worldwide 1999-2004

    • 3rd Edition
    • R. Szweda
    • English
    The third edition of this highly respected market study provides a detailed insight into the global developments of the GaAs industry to 2004, and the implications for both suppliers and users of GaAs technology.The report has been completely revised and updated with a new chapter added on competitive technologies. The report also supplies market analysis by component type and application sectors.For a PDF version of the report please call Tina Enright on +44 (0) 1865 843008 for price details.

  • Fluorine Chemistry at the Millennium

    Fascinated by Fluorine
    • 1st Edition
    • R.E. Banks
    • English
    This volume brings together contributions by leading researchers covering a wide scope so characteristic of fluorine chemistry. It is a monograph of historical character comprising personalized accounts of progress and events in areas of particular interest.There is also much to interest and instruct chemists from other disciplines as a good proportion of the chapters contain a considerable amount of 'hard' referenced information relating to modern organic, organoelemental and inorganic chemistry. Historians of chemistry and technology will no doubt be tempted to dip into this book, and surely whoever addresses the task of commemorating Moissan's achievement at the 150-years stage will bless us all in some measure for its existence.

  • Electrochemical Reactions and Mechanisms in Organic Chemistry

    • 1st Edition
    • J. Grimshaw
    • English
    Electrochemical reactions make significant contributions to organic synthesis either in the laboratory or on an industrial scale. These methods have the potential for developing more "green" chemical synthesis. Over recent years, modern investigations have clarified the mechanisms of important organic electrochemical reactions. Progress has also been made in controlling the reactivity of intermediates through either radical or ionic pathways. Now is the time to gather all the electrochemical work into a textbook.As an essential addition to the armory of synthetic organic chemists, electrochemical reactions give results not easily achieved by many other chemical routes. This book presents a logical development of reactions and mechanisms in organic electrochemistry at a level suited to research scientists and final year graduate students. It forms an excellent starting point from which synthetic organic chemists, in both academia and industry, can appreciate uses for electrochemical methods in their own work. The book is also a reference guide to the literature.

  • Applied Mineralogy in the Mining Industry

    • 1st Edition
    • W. Petruk
    • English
    Techniques of performing applied mineralogy investigations, and applications and capabilities of recently developed instruments for measuring mineral properties are explored in this book intended for practicing applied mineralogists, students in mineralogy and metallurgy, and mineral processing engineers.The benefits of applied mineralogy are presented by using in-depth applied mineralogy studies on base metal ores, gold ores, porphyry copper ores, iron ores and industrial minerals as examples. The chapter on base metal ores includes a discussion on the effects of liberation, particle sizes and surfaces coatings of Pb, Cu, Fe, Ca and So4- on the recoveries of sphalerite, galena and chalcopyrite. The chapter on gold discusses various methods of determining the quantities of gold in different minerals, including 'invisible' gold in pyrite and arsenopyrite, so that a balance of the distribution of gold among the minerals can be calculated. This book also discusses the roles of pyrite, oxygen, moisture and bacterial (thiobacillus ferrooxidans) on reactions that produce acidic drainage from tailings piles, and summarizes currently used and proposed methods of remediation of acidic drainage.

  • World Resources 2000-2001

    People and Ecosystems: The Fraying Web of Life
    • 1st Edition
    • C. Rosen
    • English
    World Resources 2000-2001, People and Ecosystems: The Fraying Web of Life focuses on the critical link between ecosystems and people and provides an overview of current global environmental and economic trends using hundreds of indicators in more than 150 countries. Until now there has not been a comprehensive, formalised process to assess human damage to our ecosystems, to establish a baseline for future actions, or to disseminate information that would aid the formulation of better policies world-wide. This book is the first reliable, comprehensive base of evidence for taking stock and taking care of the world's diverse ecosystems.deals with the critical issues that focus on the link between ecosystems and peoplehighlights the goods and services that ecosystems provide and illustrates the benefits of a better understanding and better management of the planet's natural wealthreports on pilot studies by leading scientists and international institutions assessing the state of the world's ecosystems - forests, croplands, grasslands, freshwater systems and coastal areasincreases the understanding of human dependence on natureraises awareness of environmental threatsprovides examples of wise stewardship from all corners of the globefocuses on four main issues: population and human well-being, food and water security, consumption, energy and wastes, trace emissions since the Kyoto protocolgives data tables for more than 150 countriesIt demonstrates the power of information and new digital technologies to transform the way we interact with our environment and is particularly important for environmentalists, scientists, professionals, journalists, policy-makers and students.This special Millennium Edition of the World Resources Institute's biennial report published by Elsevier Science in September 2000 in partnership with the World Resources Institute, the UN Environment Program, the UN Development Programme and the World Bank.NEW FROM APRIL 2001 -http://www.enviromo... and Environmental Modeling - An Interactive Internet Course

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