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Elsevier

Elsevier Science

  • Integrated Flow Modeling

    • 1st Edition
    • Volume 49
    • John Fanchi
    • English
    Integrated Flow Modeling presents the formulation, development and application of an integrated flow simulator (IFLO). Integrated flow models make it possible to work directly with seismically generated data at any time during the life of the reservoir. An integrated flow model combines a traditional flow model with a petrophysical model. The text discusses properties of porous media within the context of multidisciplinary reservoir modeling, and presents the technical details needed to understand and apply the simulator to realistic problems. Exercises throughout the text direct the reader to software applications using IFLO input data sets and an executable version of IFLO provided with the text. The text-software combination provides the resources needed to convey both theoretical concepts and practical skills to geoscientists and engineers.

  • Forensic Science

    • 1st Edition
    • Volume 2
    • English

  • Channelopathies

    • 1st Edition
    • F. Lehmann-Horn + 1 more
    • English
    This book describes human hereditary ion channel diseases of voltage- and ligand-gated ion channels covering the diverse fields of medicine myology, neurology, cardiology, and nephrology requiring a wide and interdisciplinary readership. Interesting parallels in pathogenetic mechanisms of disease are especially emphasized to interest even highly specialized readers in entities outside of their fields. Each author has written an objective overview of his or her particular subject in a way that should allow the reader within a short period of time to obtain a comprehensive picture of the present state of art.

  • Selected Topics in the History of Biochemistry: Personal Recollections VI

    Comprehensive Biochemistry
    • 1st Edition
    • Volume 41
    • R. Jaenicke + 1 more
    • English
    These volumes are of interest to bioscientists and to historians alike. Many authors, both as individuals and as scientists, lived and worked in the 'age of extremes' in the so-called 'short 20th century', and yet contributed significantly to the unprecedented development of life sciences in this period. These 'oral histories', set against a backdrop of the Second World War, Holocaust, and Stalinist terror, are thus of interest and relevance to older and younger generations alike. Perhaps the lessons learned from these first-hand accounts may contribute in some way to ensuring that future scientists can enjoy the fascination of science undisturbed by the avoidable tragedy of man-made events.The contributors to this volume in the Comprehensive Biochemistry series encompass a wide variety of experiences in many different countries and in very different fields of biochemistry. Some have worked close to the laboratory bench throughout their scientific life and are continuing to do so. Others have been closely engaged in organizational matters, both nationally and internationally. All mention incidents in their own career or have observed those in others that will be of interest to future historians who will record and assess the period in which our contributors have lived and worked. It was an extremely exciting time for the life sciences. It was also a period of major and often tragic historical events that deeply affected the life and work of the generation to which our contributors belong.

  • Cognition, Emotion and Autonomic Responses: The Integrative Role of the Prefrontal Cortex and Limbic Structures

    • 1st Edition
    • Volume 126
    • H.B.M. Uylings + 4 more
    • English
    Since the publication of the previous volume on the prefrontal cortex: its structures, function and pathology in Progress in Brain Research some ten years ago, new data has emerged on the prefrontal cortex and its connections and interactions with structures involved in emotional, motivational and autonomic responses. Cognition, memory and decision making appear to be influenced by emotional and autonomic responses from viscera and the internal state of the organism (e.g. 'gut feelings') induced by the outside world. This resulted in a renewed interest in the interactions of circuits involved in cognition, memory and decision making with those involved in emotional and motivational responses. Therefore, the 21st International Summer School of Brain Research, held in Amsterdam, 23-27 August 1999, was entirely devoted to the question to which extent the prefrontal cortex and related limbic structures function as an integrative center for these interactions.

  • Nervous System Plasticity and Chronic Pain

    • 1st Edition
    • Volume 129
    • J. Sandkühler + 2 more
    • English
    The mechanisms underlying the various forms of neuropathic pain are explored by leading experts in the field. The reviews provide state-of-the-art knowledge in pain research from the molecular and cellular level up to imaging of pain in the human cortex and to the perception of pain. In a truly interdisciplinary approach pain researchers and pain therapists give insights into the latest developments in the field. Some symptoms of neuropathic pain can now be understood at the molecular level, e.g. by modifications in the subunit composition of sodium channels or by the molecular properties of the vanilloid receptor. Synaptic mechanisms similar to those involved in learning and memory formation have now been discovered in pain pathways and real-time images of brain activity in human patients give novel insights into the differential processing of sensory-discriminati... versus emotional-aversive aspects of pain. This volume also documents another remarkable achievement in pain research during the past decade: The development of a common language and the assimilation of scientific concepts across disciplines. When reading the contributions, it becomes clear that new concepts and ideas developed in one arena of pain research have had impact on concepts and hypotheses important to other fields of pain research. Much of the foundation on which future pain research will rest is described in this volume. Numerous cross-references between the chapters and a detailed subject index make this book highly accessible to the reader.

  • Volume Transmission Revisited

    • 1st Edition
    • Volume 125
    • L.F. Agnati + 3 more
    • English
    Volume Transmission Revisited describes the mounting evidence that cells of the central nervous system are able to communicate via a host of chemical signals that flow through the extracellular space. Volume transmission (VT) constitutes a novel and complementary communication system to classical synaptic transmission. The new modality, which does not require specific connections between cells, leads to a reconsideration of the spatial relationships of neurons and glia, brings a new dimension to network modelling and is relevant to both short term interactions and long term tonic states of the brain.The reader will find 29 chapters describing many of the major discoveries in VT during the last decade.The most striking feature of this publication is the collecting together of many compelling examples of the ubiquitous nature of VT. These point to its increasing relevance from basic neuroscience research to clinical practice. Those working in other areas will find numerous invaluable examples of how leading investigators have gone about assembling evidence for VT.

  • Phytosfere'99 - Highlights in European Plant Biotechnology Research and Technology Transfer

    • 1st Edition
    • Volume 6
    • G.E. de Vries + 1 more
    • English
    Humans face the challenge of producing enough food to meet the demands imposed by economic, biological and agricultural factors: rising population; rising income; and an expectation of higher quality food and a more diverse diet; decreasing amount of land available for food production; lowering environmental impact of agricultural practices and preserving biodiversity.Biotech... is one of the most exciting and dynamic industries of our day. It offers us the possibility of reducing our dependence on intensive farming. Plant biotechnology is central to the search for effective, environmentally safe and economically sound alternatives to the use of chemical pesticides and the exhaustion of natural resources. Today, applied plant science has four overall goals: increased crop yield, improved crop quality, reducing production costs and reducing negative environmental impact. Biotechnology is proving its value in meeting these goals. It offers farmers higher yielding crops with lower costs of production and new outlets such as nutraceuticals and crop-based bio-factories. It offers the European economy the potential of high quality, knowledge based job creation and the European consumer better quality, tastier and more nutritious food. Though there is public concern of genetic engineering, those who are close to the science understand that this is the next big frontier to be crossed. The potential and opportunities offered by plant biotechnology must not be missed. We must go forward on that basis rather than turning our backs on the science.Phytosfere'9... provides a comprehensive overview for plant biotechnology. It combines specific scientific articles, review articles and comments from outside people on it, which is unique in European Literature.

  • Redesigning Rice Photosynthesis to Increase Yield

    • 1st Edition
    • Volume 7
    • P.L. Mitchell + 1 more
    • J.E. Sheehy
    • English
    Rice yields need to increase in order to keep pace with the growing population of Asia and to alleviate hunger and poverty. There appears, however, to be a biophysical limit associated with conventional photosynthetic pathways. The research presented in this book aims at understanding how the rice plant's photosynthetic pathway could be redesigned to overcome current yield limits. The factors controlling yield are discussed from the agronomic to the molecular level. Prospects for improving rice photosynthesis include using genetic engineering to convert rice into a C4 plant.The various chapters in this book deal with photosynthesis; a comparison of C3 and C4 pathways; genes physiology and function, and also discuss this in the broader context of economic consequences of yield improvements for poverty, the molecular genetics of photosynthesis, and ecophysiological and evolutionary perspectives of photosynthesis in wetlands.Researchers on rice, photosynthesis, agronomy, genetic engineering, and food policy will find much of interest in this book.

  • Advances in Mechanical Behaviour, Plasticity and Damage

    • 1st Edition
    • D. Miannay + 16 more
    • M. Berveiller
    • English
    Since its inception in 1991, EUROMAT has been held each year on behalf of the Federation of European Materials Societies (FEMS), and alternates between general and topical prospectives.This year's theme, Advances in Mechanical Behaviour, Plasticity and Damage, was proposed by the Societe Francaise de Metallurgie et de Materiaux (SF2M) to FEMS.This publication contains a selection of papers presented at the EUROMAT 2000 Conference, held in Tours, France on 7-9 November 2000. The aim of this Conference was to concentrate mainly on recent advances made in the investigation of the relationship between microstructures of materials and their mechanical behaviour; including, fundamentals, modelling and applications. Encompassed in the Conference's aim is the nurturing of the synergistic effect between the theoretical and applied areas in this field. This was achieved by addressing important basic and practical aspects of the mechanical behaviour and damage of materials whilst also providing significant links between various complementary approaches. All kinds of materials are covered and topics that were covered include the mechanics of solid polymers, microstructurs and micromechanisms, and the collective behavior of defects which looks at the interaction of multiple defects in a system.

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