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  • Epilepsy

    Its Phenomena in Man
    • 1st Edition
    • Mary A. B. Brazier
    • English
    Epilepsy: Its Phenomena in Man is a 16-chapter text that covers the wide field of the phenomena of epilepsy in man. This book emerged from the manuscripts presented by the scientific program of an alumni reunion of the Brain Research Institute of the University of California, Los Angeles. The introductory chapters review the role of electricity in the exploration and elucidation of the epileptic seizure, as well as the role of synaptic organization of the cerebral cortex in epilepsy. The succeeding chapters deal with the neuroglial impairment hypothesis, the particular forms of experimental epilepsy in man, and their corresponding surgical treatment. These topics are followed by discussions of the problem of synchronization in the spread of epileptic discharges leading to seizures and the behavioral correlations of generalized spike-wave discharge in the electroencephalogram... Other chapters explore the common anatomy of psychomotor epilepsy and schizophrenia; time of occurrence of seizures; the clinical ictal patterns and electrographic data in partial seizure cases; and the problems of analysis and interpretation of electrocerebral signals in human epilepsy. The concluding chapters consider the developments in direct recordings from epileptogenic regions in the surgical treatment of partial epilepsies. These chapters also examine the golgi survey concerning hippocampal pathology in temporal lobe epilepsy and the structural substrates of seizure foci. This book will prove useful to neuroscientists and the workers in biomedical fields critical for the understanding of epileptogenesis.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 7
    • Norman J. Lass
    • English
    Speech and Language: Advances in Basic Research and Practice, Volume 7 presents contributions that discuss a wide array of topics on speech and language processes and pathologies. This volume contains 11 contributions focusing on a broad range of topics on speech and language. Topics discussed in the book include auditory processing deficits in aphasic individuals and the factors that influence their performance; the functioning of the auditory system in stutterers; speech training aids for the deaf; and techniques for the assessment of language abilities in children. The morphological structure and mechanical properties of the vocal fold; the factors which participate in determining the location of a boundary signal and its amplitude; and the assessment and remediation of communication behavior in moderately retarded developmentally disabled adults are likewise covered extensively. Linguists, speech pathologists, and other language experts will find the book very insightful and informative.

  • The Mollusca

    Environmental Biochemistry and Physiology
    • 1st Edition
    • Volume 2
    • Karl M. Wilbur + 1 more
    • English
    The Mollusca, Volume 2: Environmental Biochemistry and Physiology provides information pertinent to the advances in the traditional areas of biochemistry and in other developed areas that have become a part of molluskan biochemistry. This book discusses the developments in the various aspects of molecular biomechanics and environmental biochemistry. Organized into 10 chapters, this volume begins with an overview of the comparative studies of the structure–function relationships in molluskan oxygen carriers. This text then describes the specific types and classes of molluskan respiratory proteins. Other chapters consider the nature and distribution of respiratory proteins in mollusks. This book discusses as well the oxygen equilibrium properties of gastropod hemocyanins. The final chapter deals with host–symbiont interactions in mollusks. This book is a valuable resource for researchers of the Mollusca and other phyla, as well as to teachers and qualified graduate students. Biochemists and physiologists will also find this book useful.

  • Molecules, Cells, and Parasites in Immunology

    • 1st Edition
    • Carlos Larralde + 2 more
    • English
    Molecules, Cells, and Parasites in Immunology contains the proceedings of a symposium on immunology held in Mexico City in the fall of 1979 under the auspices of the National University of Mexico (UNAM). This volume brings together prominent foreign scientists and Mexican investigators to discuss the areas of immunology that being developed at UNAM. Either in the form of reviews or of original presentations, the various authors proffer observations and ideas that generally relate to the regulation of the immune response at the molecular and cellular levels. The topic of Molecules encompasses the effect of molecular aggregation upon the triggering of physiological events, cooperative binding, and the expression of immunoglobulins during the lymphocyte differentiation process. Under the heading of Cells, there are contributions dealing with the physiological and pathological roles of interiorized antibodies; the mechanisms of antigen recognition by T cells; and the synthesis of membrane proteins by myeloma cells which somehow protect them from killer T cells. The section on Parasites includes some unique contributions on the immunology of human and animal cysticercosis and amebiasis, complemented by a general discussion of host-parasite relationships.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 6
    • Norman J. Lass
    • English
    Speech and Language: Volume 6, Advances in Basic Research and Practice is a collection of papers that discusses pathology, theories, and clinical issues related to language and speech. Some papers describe auditory discrimination and intervention techniques for articulatory defects, assessment of auditory disorders, phonological systems of deaf speakers, as well as speech and language characteristics of aging persons. Other papers discuss issues in language and cognitive assessment of black children, distortions of the supralaryngeal vocal tract, the structure of the human tongue, transformation of the acoustic signal into speech, and methods to estimate glottal volume velocity waveform properties. One paper suggests guidelines that investigators should be aware of before giving any speech discriminating tests. These guidelines include the following: use of age appropriate tests, use of culturally unbiased tests, adaption of intrapersonal testing procedures, and utilization of recorded stimulus presentation. Another paper reviews auditory processing deficits associated with brain damage and the considerations applicable to the assessment of such disorders. It also suggests treatment planning. One paper concludes that the phonological structure of a fluent speech requires that the listener employ higher level sources of knowledge while making phonetic decisions. Linguists, speech pathologists., psychologists, speech therapists, neurologists, neuropsychologists, and neurolinguists will find the collection highly relevant.

  • Recent Progress of Life Science Technology in Japan

    • 1st Edition
    • Yoji Ikawa + 1 more
    • English
    Recent Progress of Life Science Technology in Japan discusses developments in cancer research technologies in Japan. In June 1983 an intra-cabinet panel of the Japanese Government drafted a 10-year strategy for cancer control, recognizing the importance of this field of research. A scientific research group was organized to comprise two sections—the first concerning the development and evaluation of DNA technologies, and the second on protein-related technologies. In the promotion of fundamental cancer research, the development and refinement of basic technologies for each component of the ""triangle of bio-sciences""—DNA, protein, and antibody—are essential, particularly in the elucidation of tumor-inducing and tumor-suppressing genes, tumor-specific antigens, and so forth. Part I of the book details the achievements of the first group in developing automated instrumentations for DNA sequencing. The second scientific research group worked on three major subareas: (1) gene transfer and expression technologies; (2) technologies for extraction, purification, and structural analysis of cancer-related proteins; and (3) technologies for analysis and synthesis of saccharide chains. Reports from these areas are respectively grouped in Part II, Part III, and Part IV of this monograph.

  • Alcoholic Korsakoff's Syndrome

    An Information-Processing Approach to Amnesia
    • 1st Edition
    • Nelson Butters + 1 more
    • English
    Alcoholic Korsakoff's Syndrome: An Information-Processi... Approach To Amnesia presents an overview of one of the theories of amnesia, namely, the extent to which it represents an information-processi... deficit. The book discusses the clinical symptoms, neuropathology, and etiology of the alcoholic Korsakoff's syndrome; the influence of the original memory model on the research in amnesia; and the functional differences among long-term memory, short-term memory, and sensory memory. The text also describes encoding deficits; the depth of encoding and visuoperceptive deficits; as well as alternative theories of amnesia. Sensory capacities and the memory and cognitive disorders of chronic alcoholics are also considered. The book further reviews the differences among various amnesic and dementing populations. Neurologist, neuropsychologists, and students taking related courses will find the book invaluable.

  • Modulation by Covalent Modification

    • 1st Edition
    • Volume 27
    • Shmuel Shaltiel + 1 more
    • English
    Current Topics in Cellular Regulation: Volume 27, Modulation by Covalent Modification is a compendium of papers dealing with the coordination, function, or control of cellular metabolism, particularly on modulation by covalent modification. One paper reviews the cyclic cascade model in metabolic regulation that shows the model's applicability to all covalent interconvertible enzyme systems, such as those modified by phosphorylation, ADP-ribosylation, carboxymethylation, acetylation, and sulfation. Another paper discusses the hypothesis that smooth muscle contraction is regulated by a calcium-dependent phosphorylation of the myosin molecule. Studies made by Sellers and Pato suggest that a phosphatase isolated from turkey gizzard muscle (known as smooth muscle phosphatase IV) can be related to an in vivo myosin phosphatase as the phosphatase IV binds well to both myosin and thiophosphorylated myosin. Other papers describe in situ regulation studies of Excherichia coli glutamine synthethase, the posttranslational processing of the insulin proreceptor, and selenium in cellular metabolism. The compendium is suitable for biochemists, microbiologists, and academicians whose works involve research in cell biology.

  • Assembly Instructions for Polypeptide Models

    Academic Press/Molecular Design Inc. Precision Molecular Models
    • 1st Edition
    • Edward J. Barrett
    • English
    Assembly Instructions for Polypeptide Models provides assembly procedures for? polypeptide chains and for modeling the ?-helix and the parallel and antiparallel ?-pleated sheets. This text is divided into nine chapters and starts with a brief introduction to the basic unit of polypeptide or protein structure, which is the amino acid. The subsequent chapters deal with the components of the model system, including the torsion angles and the asymmetric ?-carbon atom. The remaining chapters present specific instructions for the construction of free amino acids, polypeptide end groups, side chain groups, secondary structures, and side chain torsion angles. This book will prove useful to protein and peptide scientists, organic chemists, and biochemists.

  • Speech and Language

    Advances in Basic Research and Practice
    • 1st Edition
    • Volume 3
    • Norman J. Lass
    • English
    Speech and Language: Volume 3, Advances in Basic Research and Practice is a compendium of papers that discusses theories, clinical issues, and pathology of language and speech. Some papers discuss theories of phonological development, the encoding/decoding system of language, and the application of phonological universals in speech pathology. Other papers deal with the role of the speech-language clinician, a psychological framework for speech perception, and the formulation of a model for biomechanical analysis of velopharyngeal structure and function. Several papers analyze speech control mechanisms in skilled and non-skilled speakers, the rationale for the delayed auditory feedback (DAF) treatment program, and biofeedback in relation to speech pathology. One paper cites a study of Williams (1974) that shows strategies used in learning a new phonetic system depend upon whether the speaker is still within the critical period for language learning or already well beyond it. The paper notes that if adults can ignore their previously learned sound system and be childlike again in their freedom to experiment and be sensitivity to their own results, then they can achieve supra-segmental and segmental nuances of a new language. The compendium can prove helpful for linguists, ethnologists, psychologists, speech therapists, researchers in linguistics or communications, and general readers interested in speech or learning issues.

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