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    • Dictionary of Toxicology

      • 3rd Edition
      • October 8, 2014
      • Ernest Hodgson + 1 more
      • English
      • Hardback
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      Dictionary of Toxicology, Third Edition presents a compendium of definitions of all current toxicological terminology. This authoritative reference illustrates and describes words, concepts, acronyms and symbols for both the toxicological theory and applied risk assessment, as well as providing guidance on the correct selection of problematic, similar and frequently-misused terms. Written by one of the world’s foremost experts in toxicology, and with each entry peer reviewed, Dictionary of Toxicology, Third Edition is an essential reference for all scientific, medical and legal professionals who work with or encounter the toxicological effects of contaminants on biological systems. New to this edition: an update on every entry and the inclusion of all terminology and concepts relating to molecular toxicology, nanotoxicology and computational toxicology.

    • Translational Systems Biology

      • 1st Edition
      • October 8, 2014
      • Yoram Vodovotz + 1 more
      • English
      • Paperback
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      Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money’s worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the intellectual basis of the Translational Dilemma and reports of examples in the study of inflammation, the content of Translational Systems Biology will remain relevant as technology and knowledge advances bring broad translational applicability to other diseases. Translational systems biology is an integrated, multi-scale, evidence-based approach that combines laboratory, clinical and computational methods with an explicit goal of developing effective means of control of biological processes for improving human health and rapid clinical application. This comprehensive approach to date has been utilized for in silico studies of sepsis, trauma, hemorrhage, and traumatic brain injury, acute liver failure, wound healing, and inflammation.

    • Molecular Targets in Protein Misfolding and Neurodegenerative Disease

      • 1st Edition
      • October 7, 2014
      • Pierfausto Seneci
      • English
      • Paperback
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      Aimed at "drug discoverers" – i.e. any scientist who is interested in neurodegenerative diseases in general, and in finding disease-modifying treatments in particular – the first edition of Molecular Targets in Protein Misfolding and Neurodegenerative Disease will contain both a detailed, discipline-specific coverage (paragraphs on medicinal chemistry, on clinical and preclinical characterization of compounds in development, on target identification and validation, on genetic factors influencing a pathology, etc.) and a drug discovery-oriented, overall evaluation of each target (validation, druggability, existing leads, etc.). Together these will satisfy the needs of various audiences, including in vitro biologists, pharmacologists, medicinal chemists, etc.

    • Innovation, Entrepreneurship, and the Economy in the US, China, and India

      • 1st Edition
      • October 7, 2014
      • Rajiv Shah + 2 more
      • English
      • Paperback
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      What drives innovation and entrepreneurship in India, China, and the United States? Our data-rich and evidence-based exploration of relationships among innovation, entrepreneurship, and economic growth yields theoretical models of economic growth in the context of macroeconomic factors. Because we know far too little about the key characteristics of Chinese and Indian entrepreneurs and the ways they innovate, our balanced, systematic comparison of entrepreneurship and innovation results in a new approach to looking at economic growth that can be used to model empirical data from other countries. The importance of innovation and entrepreneurship to any economy has been recognized since the pioneering work of Joseph Schumpeter. Our analysis of the major factors that affect innovation and entrepreneurship in these three parts of the world – US, China and India –provides a comprehensive view of their effects and their likely futures.

    • Biomolecular Modelling and Simulations

      • 1st Edition
      • Volume 96
      • September 30, 2014
      • English
      • Hardback
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      Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics.

    • Marine Carbohydrates: Fundamentals and Applications, Part B

      • 1st Edition
      • Volume 73
      • September 29, 2014
      • English
      • Hardback
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      Marine Carbohydrates: Fundamentals and Applications brings together the diverse range of research in this important area which leads to clinical and industrialized products. The volume, number 73, focuses on marine carbohydrates in isolation, biological, and biomedical applications and provides the latest trends and developments on marine carbohydrates. Advances in Food and Nutrition Research recognizes the integral relationship between the food and nutritional sciences and brings together outstanding and comprehensive reviews that highlight this relationship. Volumes provide those in academia and industry with the latest information on emerging research in these constantly evolving sciences.

    • Biogeochemistry of Marine Dissolved Organic Matter

      • 2nd Edition
      • September 29, 2014
      • Dennis A. Hansell + 1 more
      • English
      • Hardback
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      Marine dissolved organic matter (DOM) is a complex mixture of molecules found throughout the world's oceans. It plays a key role in the export, distribution, and sequestration of carbon in the oceanic water column, posited to be a source of atmospheric climate regulation. Biogeochemistry of Marine Dissolved Organic Matter, Second Edition, focuses on the chemical constituents of DOM and its biogeochemical, biological, and ecological significance in the global ocean, and provides a single, unique source for the references, information, and informed judgments of the community of marine biogeochemists. Presented by some of the world's leading scientists, this revised edition reports on the major advances in this area and includes new chapters covering the role of DOM in ancient ocean carbon cycles, the long term stability of marine DOM, the biophysical dynamics of DOM, fluvial DOM qualities and fate, and the Mediterranean Sea. Biogeochemistry of Marine Dissolved Organic Matter, Second Edition, is an extremely useful resource that helps people interested in the largest pool of active carbon on the planet (DOC) get a firm grounding on the general paradigms and many of the relevant references on this topic.

    • Correlative Light and Electron Microscopy II

      • 1st Edition
      • Volume 124
      • September 29, 2014
      • English
      • Hardback
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      This new volume of Methods in Cell Biology looks at methods for analyzing correlative light and electron microscopy (CLEM). With CLEM, people try to combine the advantages of both worlds, i.e. the dynamics information obtained by light microscopy and the ultrastructure as provided by electron microscopy. This volume contains the latest techniques on correlative microscopy showing that combining two imaging modalities provides more than each technique alone. Most importantly it includes the essential protocols, including tips, tricks and images for you to repeat these exciting techniques in your own lab. With cutting-edge material, this comprehensive collection is intended to guide researchers for years to come.

    • An Introduction to Probability and Statistical Inference

      • 2nd Edition
      • September 25, 2014
      • George G. Roussas
      • English
      • Hardback
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      An Introduction to Probability and Statistical Inference, Second Edition, guides you through probability models and statistical methods and helps you to think critically about various concepts. Written by award-winning author George Roussas, this book introduces readers with no prior knowledge in probability or statistics to a thinking process to help them obtain the best solution to a posed question or situation. It provides a plethora of examples for each topic discussed, giving the reader more experience in applying statistical methods to different situations. This text contains an enhanced number of exercises and graphical illustrations where appropriate to motivate the reader and demonstrate the applicability of probability and statistical inference in a great variety of human activities. Reorganized material is included in the statistical portion of the book to ensure continuity and enhance understanding. Each section includes relevant proofs where appropriate, followed by exercises with useful clues to their solutions. Furthermore, there are brief answers to even-numbered exercises at the back of the book and detailed solutions to all exercises are available to instructors in an Answers Manual. This text will appeal to advanced undergraduate and graduate students, as well as researchers and practitioners in engineering, business, social sciences or agriculture.

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