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Elsevier

Academic Press

  • Translational Neuroimmunology in Multiple Sclerosis

    From Disease Mechanisms to Clinical Applications
    • 1st Edition
    • Ruth Arnon + 1 more
    • English
    Multiple sclerosis (MS) is the most common disabling neurological disease of young adults. More than 2.3 million people are affected by MS worldwide. Symptoms can vary widely, depending on the localization and amount of the damage induced by combined inflammatory, demyelinating, and neurodegenerative processes. Although a cure for MS does not currently exist, therapies can help treat MS attacks, attenuate disease activity, reduce progress of the disease, and manage symptoms. Translational Neuroimmunology in Multiple Sclerosis provides an overview of recent findings and knowledge of the neuroimmunology of multiple sclerosis, from experimental models and the human disease to the translation of this research to immunotherapeutic strategies. Chapters describe genetic and environmental factors underlying the disease pathogenesis of MS as a basis for development of immunotherapies, immunological markers of disease activity, pharmacogenetics, and responses to therapy. Immunomodulatory therapies currently in practice and future therapeutic strategies on the horizon—such as neuroprotective strategies, stem cells, and repair promotion—are discussed. Contributed by renowned leaders in the field, this cross-disciplinary volume is a great resource for basic scientists and clinical practitioners in neuroscience, neurology, immunology, pharmacology, and in-drug development.

  • Forensic Psychology of Spousal Violence

    • 1st Edition
    • Mauro Paulino
    • English
    Exploring the dynamics between victim and offender is paramount to answering important issues of character and vital for forensic research. This involves examining the role of the victim during and after victimization; this process is especially important for spousal violence because of the interactive process between the victim and the offender.Forensic Psychology of Spousal Violence covers the phenomenon of spousal violence and its different forms, discussing the consequences of abuse, providing research tips to be used in the field, including relevant case studies and much more. The innovative approach of this text fills a void in the current understanding of spousal violence.

  • Sex Differences in Physiology

    • 1st Edition
    • Gretchen Neigh + 1 more
    • English
    Sex Differences in Physiology is an all-encompassing reference that details basic science research into sex differences in all physiological fields. It includes scientific discoveries concerning sex differences in cardiovascular, respiratory, renal, gastrointestinal, and musculoskeletal physiology. In addition, coverage of the development, endocrinology, neurophysiology, immunity, and metabolism is included, making this important reference a resource that will meet the needs of investigators interested in incorporating sex differences into their research programs, while also providing clinicians with the basis for providing the best sex-based medical treatment options available.

  • Colloid and Interface Chemistry for Water Quality Control

    • 1st Edition
    • Qing Chang
    • English
    Colloid and Interface Chemistry for Water Quality Control provides basic but essential knowledge of colloid and interface science for water and wastewater treatment. Divided into two sections, chapters 1 to 8 presents colloid chemistry including simple history and basic concepts, diffusion and Brown Motion, sedimentation, osmotic pressure, optical properties, rheology properties, electric properties, emulsion, foam and gel, and so on; chapters 9 to provides interface chemistry theories including the surface of liquid, the surface of solution, and the surface of solid. This valuable book is the only one that presents colloid and interface chemistry from the water quality control perspective. This book was written for graduate students in the area of water treatment and environmental engineering, and it could be used as the reference for researchers and engineers in the same area.

  • Formative Assessment, Learning Data Analytics and Gamification

    In ICT Education
    • 1st Edition
    • Santi Caballé + 1 more
    • English
    Formative Assessment, Learning Data Analytics and Gamification: An ICT Education discusses the challenges associated with assessing student progress given the explosion of e-learning environments, such as MOOCs and online courses that incorporate activities such as design and modeling. This book shows educators how to effectively garner intelligent data from online educational environments that combine assessment and gamification. This data, when used effectively, can have a positive impact on learning environments and be used for building learner profiles, community building, and as a tactic to create a collaborative team. Using numerous illustrative examples and theoretical and practical results, leading international experts discuss application of automatic techniques for e-assessment of learning activities, methods to collect, analyze, and correctly visualize learning data in educational environments, applications, benefits and challenges of using gamification techniques in academic contexts, and solutions and strategies for increasing student participation and performance.

  • Giant Coal-Derived Gas Fields and Their Gas Sources in China

    • 1st Edition
    • Jinxing Dai
    • English
    Giant Coal-Derived Gas Fields and Their Gas Sources in China presents a thorough look at 32 coal-derived gas fields in China. This reference book includes two main parts, the first discussing the geologic characteristics of the tectonic, stratigraphy, source and cap rock assemblage for the accumulation periods. The second part features multiple differential indexes, charts, phase states (gas, liquid, solid), and the methods used to determine the sources of the coal-derived giant gas fields. As the first comprehensive coverage of the methods of gas to source correlation in China, this book will be a classic reference for researchers working in natural gas geology and geochemistry, and teachers working in universities around the world.

  • Beyond the Bones

    Engaging with Disparate Datasets
    • 1st Edition
    • Madeleine L. Mant + 1 more
    • English
    Interdisciplinary research is a rewarding enterprise, but there are inherent challenges, especially in current anthropological study. Anthropologists investigate questions concerning health, disease, and the life course in past and contemporary societies, necessitating interdisciplinary collaboration. Tackling these ‘big picture’ questions related to human health-states requires understanding and integrating social, historical, environmental, and biological contexts and uniting qualitative and quantitative data from divergent sources and technologies. The crucial interplay between new technologies and traditional approaches to anthropology necessitates innovative approaches that promote the emergence of new and alternate views. Beyond the Bones: Engaging with Disparate Datasets fills an emerging niche, providing a forum in which anthropology students and scholars wrestle with the fundamental possibilities and limitations in uniting multiple lines of evidence. This text demonstrates the importance of a multi-faceted approach to research design and data collection and provides concrete examples of research questions, designs, and results that are produced through the integration of different methods, providing guidance for future researchers and fostering the creation of constructive discourse. Contributions from various experts in the field highlight lines of evidence as varied as skeletal remains, cemetery reports, hospital records, digital radiographs, ancient DNA, clinical datasets, linguistic models, and nutritional interviews, including discussions of the problems, limitations, and benefits of drawing upon and comparing datasets, while illuminating the many ways in which anthropologists are using multiple data sources to unravel larger conceptual questions in anthropology.

  • System Verification

    Proving the Design Solution Satisfies the Requirements
    • 2nd Edition
    • Jeffrey O. Grady
    • English
    System Verification: Proving the Design Solution Satisfies the Requirements, Second Edition explains how to determine what verification work must be done, how the total task can be broken down into verification tasks involving six straightforward methods, how to prepare a plan, procedure, and report for each of these tasks, and how to conduct an audit of the content of those reports for a particular product entity. This process-centered book is applicable to engineering and computing projects of all kinds, and the lifecycle approach helps all stakeholders in the design process understand how the verification and validation stage is significant to them. In addition to many flowcharts that illustrate the verification procedures involved, the book also includes 14 verification form templates for use in practice. The author draws on his experience of consulting for industry as well as lecturing to provide a uniquely practical and easy to use guide which is essential reading for systems and validation engineers, as well as everyone involved in the product design process.

  • Handbook for Transversely Finned Tube Heat Exchanger Design

    • 1st Edition
    • Eugene Pis’mennyi + 4 more
    • English
    Handbook for Transversely Finned Tubes Heat Exchangers Design contains detailed experimental data, correlations, and design methods for designing and improving the performance of finned tube heat exchangers. It covers the three main types, circular finned, square finned, and helical finned tube bundles. Based on extensive experimental studies and tested at leading design and research institutions, this handbook provides an extensive set of materials for calculating and designing convective surfaces from transversely finned tubes, with a particular emphasis on power plant applications.

  • Atlas of Histology of the Juvenile Rat

    • 1st Edition
    • George A Parker + 1 more
    • English
    Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42.

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