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Elsevier

Academic Press

  • Advances in Heterocyclic Chemistry

    Heterocyclic Chemistry in the 21st Century: A Tribute to Alan Katritzky
    • 1st Edition
    • Volume 119
    • English
    Heterocyclic Chemistry in the 21st Century: A Tribute to Alan Katritzky, the latest volume in the Advances in Heterocyclic Chemistry series, is the definitive resource in the field—one of great importance to organic chemists, polymer chemists, and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is also being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insights to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

  • The Evolution of the Immune System

    Conservation and Diversification
    • 1st Edition
    • Davide Malagoli
    • English
    The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors.

  • Thresholds of Genotoxic Carcinogens

    From Mechanisms to Regulation
    • 1st Edition
    • Takehiko Nohmi + 1 more
    • English
    Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation brings together current opinion and research activities from Japan, the US, and Europe on the subject of genotoxic thresholds. In regulation, it is an adage that genotoxic carcinogens have no thresholds for action, and that they impose cancer risk on humans even at very low levels. This policy is frequently called into question as humans possess a number of defense mechanisms including detoxication, DNA repair, and apoptosis, meaning there is a threshold at which these genotoxic carcinogens take action. The book examines these potential thresholds, describing the potential cancer risks of daily low-level exposure, the mechanisms involved (such as DNA repair, detoxication, translesion DNA synthesis), chemical and statistical methods of analysis, and the ways in which these may be utilized to inform policy. Thresholds of Genotoxic Carcinogens: From Mechanisms to Regulation is an essential reference for any professional researchers in genetic toxicology and those involved in toxicological regulation.

  • Linked by Blood: Hemophilia and AIDS

    • 1st Edition
    • David Green
    • English
    Linked by Blood: Hemophilia and AIDS recounts the factors responsible for the widespread infection of people with hemophilia by Human Immunodeficiency Virus (HIV)-contaminated blood and offers a prescription for addressing the challenges of future viral epidemics. The book describes the impact of AIDS on people with hemophilia, their families, and caregivers. The collection, processing, and distribution of blood in the early years of the HIV epidemic are described, including the failure of regulatory agencies to promulgate effective rules to safeguard the blood supply. The contributions of individuals and organizations that mitigated the epidemic are recognized. Linked by Blood presents recommendations for addressing the myriad medical, social, and economic challenges posed by blood-borne viral infections (AIDS, Ebola, MERS) that periodically sweep through large segments of our population.

  • Continuous Issues in Numerical Cognition

    How Many or How Much
    • 1st Edition
    • Avishai Henik
    • English
    Continuous Issues in Numerical Cognition: How Many or How Much re-examines the widely accepted view that there exists a core numerical system within human beings and an innate ability to perceive and count discrete quantities. This core knowledge involves the brain’s intraparietal sulcus, and a deficiency in this region has traditionally been thought to be the basis for arithmetic disability. However, new research findings suggest this wide agreement needs to be examined carefully and that perception of sizes and other non-countable amounts may be the true precursors of numerical ability. This cutting-edge book examines the possibility that perception and evaluation of non-countable dimensions may be involved in the development of numerical cognition. Discussions of the above and related issues are important for the achievement of a comprehensive understanding of numerical cognition, its brain basis, development, breakdown in brain-injured individuals, and failures to master mathematical skills.

  • Poincaré-Andronov-Melnikov Analysis for Non-Smooth Systems

    • 1st Edition
    • Michal Feckan + 1 more
    • English
    Poincaré-Andronov-Me... Analysis for Non-Smooth Systems is devoted to the study of bifurcations of periodic solutions for general n-dimensional discontinuous systems. The authors study these systems under assumptions of transversal intersections with discontinuity-switch... boundaries. Furthermore, bifurcations of periodic sliding solutions are studied from sliding periodic solutions of unperturbed discontinuous equations, and bifurcations of forced periodic solutions are also investigated for impact systems from single periodic solutions of unperturbed impact equations. In addition, the book presents studies for weakly coupled discontinuous systems, and also the local asymptotic properties of derived perturbed periodic solutions. The relationship between non-smooth systems and their continuous approximations is investigated as well. Examples of 2-, 3- and 4-dimensional discontinuous ordinary differential equations and impact systems are given to illustrate the theoretical results. The authors use so-called discontinuous Poincaré mapping which maps a point to its position after one period of the periodic solution. This approach is rather technical, but it does produce results for general dimensions of spatial variables and parameters as well as the asymptotical results such as stability, instability, and hyperbolicity.

  • The Gut-Brain Axis

    Dietary, Probiotic, and Prebiotic Interventions on the Microbiota
    • 1st Edition
    • Niall Hyland + 1 more
    • English
    The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders.

  • Novel Approaches of Nanotechnology in Food

    • 1st Edition
    • Volume 1
    • Alexandru Grumezescu
    • English
    Novel Approaches of Nanotechnology in Food, a volume in the Nanotechnology in the Agri-Food Industry series, represents a summary of the most recent advances made in the field of nanostructured materials that have significant impact on the agri-food industry. Because the current food market needs innovation, nanotechnology coupled with novel interdisciplinary approaches and processing methods has enabled important advances that have the potential to revolutionize agri-food sector. Nanotechnology can serve to resolve challenges faced by the food and bioprocessing industries for developing and implementing systems that can produce qualitative and quantitative foods that are safe, sustainable, and ecofriendly. This book is a valuable resource for scientists, researchers, and engineers in food science and biotechnology fields, as well as students who want information on cutting-edge technologies.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 48
    • Marc Naguib
    • English
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. This volume makes another important contribution to the development of the field by presenting theoretical ideas and research findings to professionals studying animal behavior and related fields.

  • Efficient Methods for Preparing Silicon Compounds

    • 1st Edition
    • Herbert W Roesky
    • English
    Efficient Methods for Preparing Silicon Compounds is a unique and valuable handbook for chemists and students involved in advanced studies of preparative chemistry in academia and industry. Organized by the various coordination numbers (from two to six) of the central silicon atom of the reported compounds, this book provides researchers with a handy and immediate reference for any compound or properties needed in the area. Edited by a renowned expert in the field, each chapter explores a different type of compound, thoroughly illustrated with useful schemes and supplemented by additional references. Knowledgeable contributors report on a broad range of compounds on which they have published and which are already used on a broad scale or have the potential to be used in the very near future to develop a new field of research or application in silicon chemistry.

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