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Elsevier

Academic Press

  • Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions

    • 1st Edition
    • Volume 728
    • English
    Lipids and Membranes: Metabolism, Lipidation, and Lipid-Protein Interactions, Volume 729 provides a broad snapshot of state-of-the-art methods for studying biological lipids and biomembranes. Sections in this new release cover De novo chemoenzymatic construction of lipid membranes, Photoaffinity labeling for cholesterol metabolism, Expression and Characterization of Phospholipase Cb and Ce enzymes, Assembling Retromer-coated membrane tubules for in vitro structure-function studies, Quantitative analysis of S-acylation, Inhibition of palmitoyltransferase... Exploiting protein lipidation to create peptide-based biomaterials, and much more.Additional sections discuss Optogenetic control of lipid-modifying enzyme activity using LOV domain insertions, Chemoproteomics approaches for inhibition of diacylglycerol kinases, Inhibition of sterol transfer protein function, Preparation of K-Ras4B containing synthetic modifications via expressed protein ligation, Regulation of lipin enzymes on membranes, Use of novel synthetic analogues to decipher the interactions of phosphatidic acids species, Analyzing lipid-nuclear receptor interactions, and much more.

  • Role of Biomarkers in Cancer Diagnosis and Therapeutics

    • 1st Edition
    • Sushama Talegaonkar + 2 more
    • English
    Role of Biomarkers in Cancer Diagnosis and Therapeutics offers a thorough exploration of the critical roles biomarkers play in cancer detection, diagnosis, monitoring, and therapy. Sections focus on established and emerging biomarkers like PSA and CEA, detailing their biochemical characteristics and clinical relevance, and examining metabolic pathways utilized by cancer cells, highlighting key enzymes and their therapeutic potential. The final part pf the book discusses innovative strategies targeting cell cycle checkpoints and DNA repair mechanisms, including synthetic lethality through PARP inhibitors. This essential resource provides researchers and clinicians with insights into novel metabolic targets and cutting-edge treatment strategies.By addressing current applications and future challenges, including the integration of AI and multi-omics approaches, the book equips readers with actionable knowledge to advance personalized cancer care and navigate the dynamic landscape of oncology.

  • Unlocking the Secrets of Extracellular Vesicles and Exosomes

    A Journey into the Cutting-Edge Frontier of Cellular Communication
    • 1st Edition
    • Chandrashekhar Singh + 4 more
    • English
    Unlocking the secrets of extracellular vesicles and exosomes: A journey into the cutting-edge frontier of cellular communication provides a comprehensive overview of the latest advances and research on extracellular vesicles (EVs) and exosomes. The book begins with a historical introduction to the field and how this has evolved since EVs were first observed, before exploring their cellular mechanisms and approaches to study their isolation, characterization, and function. It then delves into exosomes in health and disease, considering their role across cancer, regenerative medicine, neurological disorders, and metabolic disorders, highlighting their potential as biomarkers for disease diagnosis. The book moves on to discuss cutting-edge technology for the engineering of EVs and exosomes, considering how the integration of AI, machine learning, and nanotechnology can be utilized to expand the therapeutic capabilities of EV and exosome-based applications. It then closes with chapters covering novel applications in nutraceutical and cosmetic production, and a look towards the future potential of EVs and exosomes. Unlocking the secrets of extracellular vesicles and exosomes offer a thorough exploration of EV and exosome research, covering various dimensions from basic science to clinical applications and future perspectives. It is an ideal guide for researchers working across a diverse range of disciplines, including cell biology, molecular biology, biotechnology, therapeutics, and biomedicine.

  • Host-Microbe Co-metabolism System in Health and Disease

    • 1st Edition
    • Xiao Zheng + 1 more
    • English
    Host-Microbe Co-metabolism System in Health and Disease is an easy-to-follow reference of research progress in host-microbiome co-metabolism system (HMMS) and how this frontier could imply a better understanding of health, disease, and the discovery of novel drugs. The book summarizes recent studies that are progressing to complete a panorama of the host-microbiome co-metabolism system (HMMS) in health and disease. It discusses how sophisticated bioanalytical tools, tractable model organisms, and artificial intelligence could be integrated to answer key biological questions related to HMMS in the broader context of human health and drug discovery.

  • Role of Nanocarriers in Management of Non-Hodgkin Lymphoma

    • 1st Edition
    • Bhupendra G. Prajapati + 1 more
    • English
    Role of Nanocarriers in Management of Non-Hodgkin Lymphoma is a pivotal resource that explores the transformative impact of nanotechnology on the diagnosis, treatment, and management of non-Hodgkin’s lymphoma (NHL). This comprehensive guide bridges the gap between innovative research and clinical application, focusing on advancements in polymeric nanoparticles, lipid carriers, carbon nanotubes, and immunotherapy approaches. The book provides an in-depth analysis of current technologies and future directions in integrating nanocarriers into NHL management. Each chapter offers evidence-based insights and mechanisms of action, emphasizing the synergy between immunotherapy, precision medicine, and nanotechnology. This resource benefits its academic audience by equipping healthcare professionals with innovative strategies to improve treatment outcomes and inspiring researchers to explore novel therapeutic pathways. By fostering interdisciplinary collaboration among oncologists, pharmaceutical developers, and nanotechnology experts, the book ultimately guides future research to enhance patient care in the rapidly evolving field of non-Hodgkin’s lymphoma management.

  • Explainable AI in Clinical Practice

    Methods, Applications, and Implementation
    • 1st Edition
    • Arvind Panwar + 4 more
    • English
    Explainable AI in Clinical Practice: Methods, Applications, and Implementation bridges the gap between artificial intelligence capabilities and their practical implementation in healthcare. The book explores applications of explainable AI in diagnostic support and treatment planning, offering insights into making AI systems interpretable and accountable. Through real-world case studies and ethical frameworks, readers learn to transform opaque AI systems into tools that enhance clinical practice while maintaining high patient care standards. This volume unites leading experts to provide a comprehensive framework for implementing explainable AI, ensuring that AI-driven decisions are transparent, trustworthy, and clinically sound. Targeted solutions in the book cater to diverse stakeholders in the healthcare AI ecosystem. Healthcare professionals will gain confidence in integrating AI tools, while technical teams will receive implementation guidelines. This book is essential for anyone seeking to responsibly and effectively navigate the complexities of AI in healthcare.

  • Sustainable Development of Renewable Energy

    Volume 2: Opportunities in Production, Storage, and Integration
    • 1st Edition
    • Mejdi Jeguirim
    • English
    Sustainable Development of Renewable Energy: Volume 2—Opportunities in Production, Storage, and Integration is the sixth book in the Advances in Renewable Energy Technologies series. Based on the key themes of the International Renewable Energy Congress (IREC), this volume looks at the production performance of renewable energy sources and emerging production processes.Containing all major renewable energy technologies in individual chapters, this reference includes some of the most dynamic developments, good practices, and future concepts in solar energy systems, energy storage, geothermal energy, bioenergy, wind energy, fuel cell, and hydrogen production, as well as in policy and regulation. By reviewing these state-of-the-art advances, considering them with real work application, and analyzing key challenges, this book provides readers with an up-to-date source on renewable energy grid integration and its importance in aiding the energy transition.This is a valuable resource for graduates, researchers, professors, and industry professionals involved in the renewable energy sector, as well as advanced engineering courses dealing with renewable energy, sources, thermal and electrical energy production, and sustainability.

  • Roadmap to Successful Digital Health Ecosystems

    A Global Perspective
    • 2nd Edition
    • Evelyn J.S. Hovenga AM + 1 more
    • English
    Roadmap to Successful Digital Health Ecosystems: A Global Perspective, Second Edition, explores the transformative integration of digital health technologies to enhance healthcare delivery and patient outcomes. This book provides a comprehensive overview of the evolving landscape of digital health, focusing on next-generation systems and the role of artificial intelligence in creating efficient healthcare ecosystems. The revised content covers topics such as regional implementation experiences, workforce management, and precision healthcare. New chapters highlight advancements in digital health technologies, case studies from Jamaica and Africa, and strategies for addressing fragmentation in healthcare systems. The book emphasizes ethical AI use and proactive, integrated healthcare approaches. For the academic audience, this revision serves as an essential resource, compiling cutting-edge research and practical applications that inform best practices in digital health. It equips researchers, educators, and practitioners with the knowledge needed to navigate the complexities of digital health ecosystems and drive innovation in their fields.

  • Keynesian Behavioral Macroeconomics

    • 1st Edition
    • Theodore Koutsobinas
    • English
    Keynesian Behavioral Macroeconomics analyzes Keynes’s landmark contributions in behavioral economics and develops a new and fresh genre of macroeconomic analysis. It compels us to consider seriously the earlier-generation warnings about the impact of investors’ animal spirits and financiers’ liquidity-presence using cognitive-based and social psychology heuristics. Innovative in its subject matter, approach, theoretical development and policy prescriptions, this constructivist pluralist approach can contribute to important debates. This fresh look in macroeconomics can fruitfully be applied by macroeconomists, policymakers, and market participants to prevent effective demand shortages, stimulate the economy, preserve job creation, and impact redistribution, sustainability and social inclusion.In this timely book, Theodore Koutsobinas develops a synthesis of Keynes’s macroeconomic theory with contemporary developments in behavioral macroeconomics to analyze urgent real-world challenges, and he proposes successful solutions for macroeconomic policy. This volume uniquely explains how Keynes’s magnificent, crucial, but long-forgotten dynamics can be analyzed on the basis of behavioral foundations to explain amplified global finance cycles, booms and busts, and macroeconomic instability with harmful effects on incomes and jobs.

  • AI, Blockchain and Social Network on Urban Crisis Management: Leveraging Emerging Technologies for Disaster Response and Resilience in Smart Cities

    • 1st Edition
    • Volume 142
    • English
    AI, Blockchain and Social Network on Urban Crisis Management: Leveraging Emerging Technologies for Disaster Response and Resilience in Smart Cities, Volume 142 in the Advances in Computers series, examines how cutting-edge digital technologies are reshaping disaster preparedness and response. This volume highlights the convergence of artificial intelligence, blockchain, and social network analysis to predict, prevent, and manage urban crises. Chapters explore Nutrient Recovery from Livestock Effluent in a Circular Economy Approach, Leveraging Artificial Intelligence for Deforestation Monitoring and Conservation in the Colombian Amazon, Experimental and Theoretical Investigation of Diffusion in Hydrocarbon-Based Dense Fluids for Enhanced Oil Recovery, and much more.Additional chapters cover Navigating the Complexities: Challenges, Weaknesses, and Hurdles in Integrating AI, Blockchain, and Social Networks for Urban Crisis Management, Educating Europe's Guardians: Ethical AI and Emerging Technologies in Law Enforcement Training for Urban Crisis Management, The Intersection of AI, Blockchain, and Social Networks in Urban Crises Management, Application of Graph Theory in Disaster Management for Efficient Handling and Mobilizing of Resources and Logistics, Analyzing the Role of Social Networks in Urban Crisis Management through Citizen Participation and Smart Technological Deployment, and many more important and timely topics.

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