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Elsevier

Academic Press

  • ESKAPE Pathogens

    Virulence, Resistance, and Management
    • 1st Edition
    • Karthikeyan Ramalingam
    • English
    ESKAPE Pathogens: Virulence, Resistance, and Management provides comprehensive coverage on ESKAPE pathogens, including their virulence mechanisms, resistance patterns, and challenges in their management. The book offers the latest information on ESKAPE pathogens' pathogenicity, mechanisms of antibiotic resistance, and innovative approaches to manage these pathogens. It explores recent advancements in the field of genomics, proteomics, and transcriptomics that could potentially provide valuable insights into the mechanisms and genetic basis of antibiotic resistance in ESKAPE pathogens. Finally, the book highlights the need for alternative treatment options and innovative management strategies to combat the emergence of multidrug-resistant strains.This is a helpful resource to researchers, clinicians, educators, industry professionals, and advanced students interested in the latest research and strategies for combating multidrug-resistant pathogens.

  • Mucins

    • 1st Edition
    • Volume 732
    • English
    Mucins, Volume 732 serves as a valuable resource for researchers aiming to investigate mucin biology in greater depth, offering a wide range of experimental approaches and analytical strategies. Topics in this new release cover Enrichment/isolation... glycoproteomics, Mucinase cleavage characterization and usage in glycoproteomics, Fluorescent protein-based FRET substrates for activity screening of mucinases, Development of clinical lectin assays based on MS glycomic discovery, Enzymatic selective sulfation of synthetic mucins, cryoEM, Cell-based mucin arrays and glycoengineering, CRISPR screens to characterize and identify glycan-binding proteins, and much more.Additional sections cover MD Simulations, Interactions with pathogenic bacteria, Interactions with microbiota, Covalent crosslinking of mucins, Liquid Glycan and Liquid Lectin Array-based exploration of musin recognition, Quantification of mucins, Mucins in IBD, Investigations of mucins and innate immunity, Generating synthetic mucin glycopeptides, and Microscopy and imaging.

  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 58
    • English
    Advances in the Study of Behavior, Volume 58, an annual volume in the field of behavior science, brings together cutting-edge research, theoretical advances, and surveys the latest findings across learning, conditioning, memory, perception, decision-making, and related areas, while also blending behavioral analysis with neuroscience, genetics, and computational modeling. Chapters in this new release include Staying in Sync: Behavioral Synchrony and Cooperation in Dolphins, Bridging human and primate culture: toward a comparative evolutionary framework, Natural and sexual selection on reproduction in the sand goby – a dynamic mosaic in time and space, and Beyond protection from predators: the perks of being warningly colored.

  • Protein Misfolding and Human Diseases

    Deciphering the Central Role of Pathological Aggregation
    • 1st Edition
    • Pranav Kumar Prabhakar + 2 more
    • English
    Protein Misfolding and Human Diseases: Deciphering the Central Role of Pathological Aggregation investigates the misfolding of proteins and implications for a variety of debilitating conditions. The book comprehensively overviews pathological protein aggregation, exploring its mechanisms in specific illnesses, including Alzheimer's disease, Parkinson’s disease, Huntington’s disease, prion diseases, ALS, and systemic amyloidosis. It addresses disrupted cellular pathways and failures in protein homeostasis during aging, delineating the unifying principles across protein conformational disorders. Sections feature structural insights into protein aggregates from amyloid fibrils to inclusion bodies and offer therapeutic strategies to disrupt aggregation pathways, enhance cellular protein quality control, and provide immunotherapy solutions.Finally, the book closes with a discussion of the latest advances in research and considerations for future directions to combat protein aggregation. It will serve as an invaluable reference on the intricacies of protein misfolding and its clinical implications. Researchers, academics and graduate students working across these fields will benefit from this comprehensive guide. Additionally, clinicians and healthcare professionals will find it invaluable for understanding the molecular basis of protein misfolding disorders.

  • Epidemic Modeling

    Principles, Algorithms, and Applications
    • 1st Edition
    • Teddy Lazebnik
    • English
    Epidemic Modeling: Principles, Algorithms, and Applications is a comprehensive introduction and practical guide to building, understanding, and applying epidemiological models in real-world contexts. Bridging theory and practice, the book walks readers through the full modelling pipeline from the biological, social, and political drivers of disease spread to classical compartmental models such as SIR, and onward to modern computational techniques including agent-based simulation, machine learning, and optimization under uncertainty. Each chapter builds progressively, pairing clear conceptual explanations with hands-on code, real data examples, and step-by-step methods that readers can adapt to new challenges. Drawing on extensive academic and industry experience, the text emphasizes how modelling decisions are made in practice addressing real-world complications such as incomplete data, reporting delays, and measurement error. Designed as both a learning resource and long-term reference, the book equips readers to move beyond running existing models to designing, evaluating, and communicating their own. It also fosters a shared language across disciplines, helping technical and non-technical audiences engage meaningfully with modelling insights. Timely and practical, this book empowers the next generation of modelers and decision-makers to respond effectively to an increasingly complex epidemic landscape.

  • Protein-Based Nanoparticles in Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Protein-based Nanoparticles in Drug Delivery is a comprehensive book aimed at pharmaceutical scientists and researchers both in academia and corporate environments focused on nanotechnology drug delivery and pharmaceutical-relat... disciplines. The book covers the design and characterization of various protein nanoparticles, sheds light on the power of an endogenous substance as a drug delivery system, and highlights the possible future trends in the use of protein-based drug delivery. It covers in-depth novel applications of protein-based drug delivery from fundamental to most current use cases. The book comprises three parts. Part one is devoted to the foundations of protein-based drug delivery, including nanocarriers development, drug encapsulation, targetability, and in vivo properties. Part two explores the applications of protein-based nanoparticles in drug delivery, covering topics such as protein nanoparticles in cancer therapy, genetic material delivery, and nanocarriers based on milk protein, silk, and gliadin. Part three addresses recent advances and regulatory aspects of protein-based nanoparticles in drug delivery, including clinical translation, challenges, biological toxicity, and environmental hazards associated with protein-based nanoparticles. Protein-based Nanoparticles in Drug Delivery provides a complete journey of protein-based drug delivery, offers an in-depth understanding of the design and characterization of various protein nanoparticles, and highlights possible future trends in this field. Pharmaceutical scientists will benefit from the novel applications of protein-based nanoparticles drug delivery approaches in the biological field. Nanotechnologists, biologists, chemists, physicists, engineers, and clinicians will also benefit from the foundational content provided as a basis to support communication and tackle the multidisciplinary challenges associated with research in this exciting field.

  • Green Intrusion Detection Systems for IoT

    • 1st Edition
    • Saeid Jamshidi + 3 more
    • English
    Green Intrusion Detection Systems for IoT tackles the pressing security challenges posed by the rapid expansion of the Internet of Things (IoT). The book delves into innovative, lightweight security models and energy-aware IDS mechanisms that strike a balance between security efficacy, computational efficiency, and environmental sustainability. Sections discuss the transformative role of IoT and the need for sustainable security solutions, highlight the distinctions between traditional and Green IDS, focus on lightweight security models essential for resource-constrained IoT devices, and delve into energy-efficient network designs.Additional sections explore green IDS mechanisms, including machine learning and distributed approaches, IoT vulnerabilities and mitigation strategies, practical examples of sustainable IDS in various smart environments, real-world case studies, and future directions in sustainable IoT security. The book concludes with actionable recommendations that align technological advancements with global sustainability goals.

  • Applied Charged Particle Optics: Part I

    • 1st Edition
    • Volume 238
    • English
    Advances in Imaging and Electron Physics, Volume 238 merges two long-running serials, Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy.

  • Intelligent Railway Alignment Design

    • 1st Edition
    • Hao Pu + 4 more
    • English
    Intelligent Railway Alignment Design offers a comprehensive exploration of intelligent railway alignment optimization. The book considers a variety of critical topics, starting with the optimal selection of key technical standards for railway design and then introduces the comprehensive geographic information model. The methods for evaluating the suitability of the railway alignment based on the comprehensive geographic information model are discussed, together with economic optimization models aimed at cost-effective railway alignment design. In addition, the book considers optimization models for managing risks related to typical geological hazards and minimizing environmental impacts.Intelligent search algorithms for solving railway alignment optimization models are explained in detail, including corridor searching algorithms and 3D alignment searching algorithms. Additionally, the book explores concurrent optimization strategies for coordinating railway alignments with stations and large temporary engineering projects. Finally, it introduces intelligent models and methods for reconstructing and optimizing existing railway alignments, ensuring that both new and updated railways operate efficiently and sustainably.

  • Smart Healthcare 2.0

    Integrating Digital Twins with AI-Driven Predictive Analytics
    • 1st Edition
    • Ramesh Chandra Poonia + 1 more
    • English
    Smart Healthcare 2.0: Integrating Digital Twins with AI-Driven Predictive Analytics offers a groundbreaking exploration of how digital twin technology, combined with real-time sensing and predictive analytics, is transforming healthcare delivery. As the global healthcare landscape shifts toward proactive, personalized care, this book addresses the urgent need for comprehensive resources that unify artificial intelligence, Internet of Things (IoT), and biomedical engineering within the digital twin framework. It provides an essential guide for researchers, engineers, and clinicians aiming to harness virtual patient models and data-driven insights to improve health outcomes and system efficiency in the era of ubiquitous healthcare.This volume covers a wide spectrum of topics, starting with foundational concepts of digital twins in precision health and advancing through smart sensing technologies, scalable system architectures, and AI-powered predictive analytics. Readers will explore detailed discussions on edge-cloud computing, secure communication protocols including blockchain, and simulation platforms that enable virtual patient modeling. The book also addresses critical themes such as chronic disease management, emergency response optimization, ethical AI deployment, interoperability standards, and workforce readiness. Real-world case studies and future-focused chapters on cognitive twins and quantum simulation provide a rich, multidisciplinary perspective.

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