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Elsevier

Academic Press

  • Self-assessment Questions for Clinical Molecular Genetics

    • 1st Edition
    • Haiying Meng
    • English
    Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge.

  • Biochemistry of Collagens, Laminins and Elastin

    Structure, Function and Biomarkers
    • 2nd Edition
    • Morten Karsdal
    • English
    There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease.

  • Neuroscience of the Nonconscious Mind

    • 1st Edition
    • Rajendra Badgaiyan
    • English
    Neuroscience of the Nonconscious Mind includes novel concepts and insights on the brain mechanisms that control nonconscious mental functions, some of which were developed in the author’s laboratory. The book describes neuroscience of conventional nonconscious mental functions, along with not so conventional functions like creativity, hypnosis and extrasensory perception, thus making it a very unique reference. This thought provoking book for students of mind, brain and consciousness will help explain concepts and introduce the science behind the nonconscious.

  • Genome Chaos

    Rethinking Genetics, Evolution, and Molecular Medicine
    • 1st Edition
    • Henry H. Heng
    • English
    Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine.

  • Wildlife Conservation in Africa

    A Scientific Approach
    • 1st Edition
    • S.S. Ajayi
    • English
    Wildlife Conservation in Africa: A Scientific Approach presents comprehensive management strategies for the consumptive and non-consumptive utilization of wildlife across Sub-Saharan Africa. It describes African economies that are currently dependent on wildlife resources and prescribes strategies for conserving biodiversity in both forests and animals in ecosystems across the continent. The book covers the history and current status of how Africa’s culture, traditions, healthcare and food sources are woven intricately around the local wildlife and resources. It is a necessary resource for researchers and practitioners in wildlife and ecological conservation, but is also useful for administrators and managers of protected areas.

  • Pregnancy and the Pharmaceutical Industry

    The Movement towards Evidence-Based Pharmacotherapy for Pregnant Women
    • 1st Edition
    • Kristine E. Shields
    • English
    Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications used during pregnancy as it is impossible to extrapolate that information from drug studies on men and non-pregnant women. As a majority of pregnant women confront a medical condition during their pregnancy, from simple pain, to ongoing or new medical issues, this book quantifies the current absence of pregnant women in drug studies and identifies ethical issues, barriers, litigation fears and opportunities. Those in the pharmaceutical industry, IRB members who approve or deny drug study plans, doctors, nurses and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.

  • Human Brainstem

    Cytoarchitecture, Chemoarchitecture, Myeloarchitecture
    • 1st Edition
    • George Paxinos + 2 more
    • English
    Human Brainstem: Cytoarchitecture, Chemoarchitecture, Myeloarchitecture explores how the human brainstem has been impeded by the unavailability of an up-to-date, comprehensive, diagrammatic and photographic atlas. Now, with the first detailed atlas on the human brainstem in more than twenty years, this book presents an accurate, comprehensive and convenient reference for students, researchers and pathologists.

  • Evaluating Water Quality to Prevent Future Disasters

    • 1st Edition
    • Volume 11
    • English
    Evaluating Water Quality to Prevent Future Disasters, volume 11 in the Separation Science and Technology series, covers various separation methods that can be used to avoid water catastrophes arising from climate change, arsenic, lead, algal bloom, fracking, microplastics, flooding, glyphosphates, triazines, GenX, and oil contamination. This book provides a valuable resource that will help the reader solve their potential water contamination problems and help them develop their own new approaches to monitor water contamination.

  • Chromatin Signaling and Neurological Disorders

    • 1st Edition
    • Volume 12
    • English
    Chromatin Signaling and Neurological Disorders, Volume Seven, explores our current understanding of how chromatin signaling regulates access to genetic information, and how their aberrant regulation can contribute to neurological disorders. Researchers, students and clinicians will not only gain a strong grounding on the relationship between chromatin signaling and neurological disorders, but they'll also discover approaches to better interpret and employ new diagnostic studies and epigenetic-based therapies. A diverse range of chapters from international experts speaks to the basis of chromatin and epigenetic signaling pathways and specific chromatin signaling factors that regulate a range of diseases. In addition to the basic science of chromatin signaling factors, each disease-specific chapter speaks to the translational or clinical significance of recent findings, along with important implications for the development of epigenetics-based therapeutics. Common themes of translational significance are also identified across disease types, as well as the future potential of chromatin signaling research.

  • Epigenetics and Regeneration

    • 1st Edition
    • Volume 11
    • English
    Epigenetics and Regeneration compiles the first foundational reference on epigenetic mechanisms governing tissue development, repair, homeostasis, and regeneration, as well as pathways to employ these mechanisms in clinical practice and translational science. In this book, life science researchers, clinicians, and students will discover an interdisciplinary resource bringing together common themes in the field, background overviews, research methods, recent advances, and opportunities for drug discovery. Throughout this volume, special attention is paid to pre-clinical and first clinical studies aimed at increasing the regenerative potential of damaged tissues by epigenetic drugs, as well as innovative, discipline spanning strategies to enhance cell reprogramming. As an all-inclusive, evidence-based volume, Epigenetics and Regeneration will stimulate discussion and boost new research in this fascinating and impactful area of translational epigenetics.

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