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Academic Press

  • Echinoderms Part B

    • 1st Edition
    • Volume 151
    • English
    Echinoderms, Volume 151, the latest release in the Methods in Cell Biology series, highlights advances in the field, with this update presenting chapters on Echinoderm Genome Databases, analysis of gene regulatory networks, using ATAC-seq and RNA-seq to increase resolution in GRN connectivity, multiplex cis-regulatory analysis, experimental approaches GRN/signal pathways, BACs, analysis of chromatin accessibility using ATAC-seq, analysis of sea urchin proteins /Click IT, CRISPR/Cas9-mediated genome editing in sea urchins, super-resolution and in toto imaging of echinoderm embryos, and methods for analysis of intracellular ion signals in sperm, eggs and embryos.
  • Clinical Genome Sequencing

    Psychological Considerations
    • 1st Edition
    • Aad Tibben + 1 more
    • English
    Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.
  • Pediatric Anxiety Disorders

    • 1st Edition
    • Scott N. Compton + 2 more
    • English
    Pediatric Anxiety Disorders provides a critical, updated and comprehensive overview of anxiety disorders in children and adolescents based on the current state of empirical research. The book provides specific clinical recommendations which integrate new knowledge from neuroscience and innovative delivery formats for interventions. This is the first reference to examine anxiety diagnoses in accordance with the latest edition of the DSM-5, including childhood onset disorders, such as Separation Anxiety Disorder, Selective Mutism, Specific Phobia, Social Anxiety Disorder, Panic Disorder, Agoraphobia and Generalized Anxiety Disorder. The book assists clinicians in critically appraising the certainty of the evidence-base and the strength of clinical recommendations.
  • Pharmaceutical Quality by Design

    Principles and Applications
    • 1st Edition
    • Sarwar Beg + 1 more
    • English
    Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process.
  • Intelligent Speech Signal Processing

    • 1st Edition
    • Nilanjan Dey
    • English
    Intelligent Speech Signal Processing investigates the utilization of speech analytics across several systems and real-world activities, including sharing data analytics, creating collaboration networks between several participants, and implementing video-conferencing in different application areas. Chapters focus on the latest applications of speech data analysis and management tools across different recording systems. The book emphasizes the multidisciplinary nature of the field, presenting different applications and challenges with extensive studies on the design, development and management of intelligent systems, neural networks and related machine learning techniques for speech signal processing.
  • The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it.
  • Essential MATLAB for Engineers and Scientists

    • 7th Edition
    • Daniel T. Valentine + 1 more
    • English
    Essential MATLAB for Engineers and Scientists, Seventh Edition, provides a concise, balanced overview of MATLAB's functionality, covering both fundamentals and applications. The essentials are illustrated throughout, featuring complete coverage of the software's windows and menus. Program design and algorithm development are presented, along with many examples from a wide range of familiar scientific and engineering areas. This edition has been updated to include the latest MATLAB versions through 2018b. This is an ideal book for a first course on MATLAB, but is also ideal for an engineering problem-solving course using MATLAB.
  • Ubiquitin-dependent Protein Degradation

    • 1st Edition
    • Volume 619
    • English
    Ubiquitination and Protein Stability - Part B, Volume 619, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Topics of note include chapters on Assays of SUMO protease function in mammalian cells, In vitro analysis of proteasome-associate... USP14 activity for substrate degradation and deubiquitylation, Methods to study proteasome regulatory particle assembly, Native mass spectrometry approaches to study the proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway, and much more.
  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 29
    • Aleš Iglič︎ + 2 more
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 29, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.
  • Advances in the Study of Behavior

    • 1st Edition
    • Volume 51
    • Marc Naguib
    • English
    Advances in the Study of Behavior, Volume 51, provides users with the latest insights in this ever-evolving field. Users will find new information on a variety of species, including The troublesome gift: the spermatophylax as a purveyor of sexual conflict and coercion, Conformity and over-imitation: an integrative review of two forms of hyper-reliance on social learning, Copulatory behavior and genital morphology in vertebrates, Sexual selection in polyandrous societies: Lessons from the fowl, Sensory information in social insects, Evolution of female coloration, what have we learned from birds in general and blue tits in particular, Sexual selection and social behavior in spiders, and more.