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Elsevier

Academic Press

  • Smart Healthcare 2.0

    Integrating Digital Twins with AI-Driven Predictive Analytics
    • 1st Edition
    • Ramesh Chandra Poonia + 1 more
    • English
    Smart Healthcare 2.0: Integrating Digital Twins with AI-Driven Predictive Analytics offers a groundbreaking exploration of how digital twin technology, combined with real-time sensing and predictive analytics, is transforming healthcare delivery. As the global healthcare landscape shifts toward proactive, personalized care, this book addresses the urgent need for comprehensive resources that unify artificial intelligence, Internet of Things (IoT), and biomedical engineering within the digital twin framework. It provides an essential guide for researchers, engineers, and clinicians aiming to harness virtual patient models and data-driven insights to improve health outcomes and system efficiency in the era of ubiquitous healthcare.This volume covers a wide spectrum of topics, starting with foundational concepts of digital twins in precision health and advancing through smart sensing technologies, scalable system architectures, and AI-powered predictive analytics. Readers will explore detailed discussions on edge-cloud computing, secure communication protocols including blockchain, and simulation platforms that enable virtual patient modeling. The book also addresses critical themes such as chronic disease management, emergency response optimization, ethical AI deployment, interoperability standards, and workforce readiness. Real-world case studies and future-focused chapters on cognitive twins and quantum simulation provide a rich, multidisciplinary perspective.

  • Next-Generation Onco-Therapeutics

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Next-Generation Onco-Therapeutics explores the latest advancements in cancer treatment, focusing on personalized medicine and innovative therapeutic strategies. The book serves as a comprehensive resource for understanding how emerging technologies can reshape oncological care, providing insights into effective and compassionate patient management. Content explores cutting-edge developments in cancer therapies, featuring clinical examples and case studies that illustrate the practical application of new treatment modalities. It emphasizes the importance of integrative approaches that address the diverse needs of cancer patients, ensuring that healthcare professionals are equipped with the most current information in this rapidly evolving field. This book also addresses the urgent need for updated resources in oncological therapeutics, bridging the gap between traditional practices and modern innovations. By synthesizing diverse perspectives and evidence-based insights, it empowers healthcare providers, researchers, and policymakers to enhance treatment outcomes and improve patient well-being in the era of personalized medicine.

  • Current Approaches to Cryo-electron Microscopy

    • 1st Edition
    • Volume 223
    • English
    Cryo-electron microscopy (cryo-EM) has emerged as a transformative technique in structural biology, driving an exponential increase in the number of structures deposited in the Protein Data Bank. Current workflows now routinely achieve the near-atomic resolution essential for understanding the molecular pathology of neurodegenerative and metabolic disorders. This provides a comprehensive overview of the field, tracing the evolution from early structural studies to modern pipelines powered by deep-learning algorithms for helical reconstruction. We address the persistent bottleneck of sample preparation, detailing the physical challenges of fibril clumping and interfacial adsorption, alongside emerging solutions to these problems. Furthermore, we examine the complexities of structural polymorphism, discussing how environmental factors and seeding drive conformational diversity and how this heterogeneity impacts biochemical assays. Finally, we highlight the translational value of these high-resolution maps, demonstrating how they enable the rational, structure-based design of peptide inhibitors and small molecules capable of disaggregating pathogenic fibrils.

  • Advances in Heat Transfer

    • 1st Edition
    • Volume 61
    • English
    Advances in Heat Transfer, Volume 61 provides a comprehensive overview of the latest developments, emerging trends, and innovative research in the field of heat transfer. Covering both fundamental concepts and practical applications, this volume brings together contributions from leading experts addressing topics such as conduction, convection, radiation, phase change, and multi-phase flows.

  • Starch-Based Materials

    Principles and Applications
    • 1st Edition
    • Ming Miao + 1 more
    • English
    Starch-Based Materials: Principles and Applications explores the cutting-edge research and development of starches as biodegradable, renewable biomaterials addressing urgent environmental concerns associated with non-biodegradable polymers. This comprehensive volume delves into the structural characteristics of starches, recent advances in their physical, chemical, and enzymatic modifications, and emerging technologies that expand their use beyond traditional food applications. It highlights innovative approaches to enhance nutritional value and health benefits, including the design of gluten-free products and specialized foods, while also covering industrial uses such as hydrogels and controlled release systems. Despite extensive prior research on starch packaging and non-food uses, there is a significant gap in current literature regarding modern starch modifications and their multifunctional applications across food, pharmaceutical, medical, and biomaterial fields. This book addresses this gap by providing a timely, authoritative summary of recent scientific findings, aiming to stimulate innovation and sustainable development in starch utilization. It is an essential reference, particularly in courses related to food chemistry, food analysis, nutrition, packaging, pharmaceutical applications, and specialized medical fields such as controlled release technologies.

  • Polyphenols in Wound Healing

    • 1st Edition
    • Bushra Akhtar + 1 more
    • English
    Polyphenols in Wound Healing presents a comprehensive exploration of how naturally occurring compounds—polyphenol... a pivotal role in advancing wound care therapies. Divided into four thoughtfully curated sections, the book begins with an in-depth review of the science of wound healing, introducing readers to the fundamentals of skin physiology, the various types of wounds, and key therapeutic targets. Other sections delve into the world of polyphenols, offering detailed information on their natural sources, especially medicinal plants, and the techniques used for their extraction, isolation, and purification. A focus on how polyphenols act on biological pathways to support wound healing is also included.This includes mechanisms such as reducing inflammation, combating oxidative stress, modulating matrix metalloproteinases, enhancing collagen synthesis, and promoting tissue regeneration and angiogenesis. Each chapter is backed by current research, offering mechanistic insights that bridge traditional knowledge with modern biomedical science. This structured and progressive organization ensures that all key aspects of polyphenol-based wound healing are clearly presented and easy to follow, making the book highly accessible for researchers, clinicians, and students alike.

  • Basal Ganglia Dynamics

    From Motor Units to Networked Chaotic Oscillators
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Basal Ganglia Dynamics: From Motor Units to Networked Chaotic Oscillators addresses the critical need for new theoretical frameworks in understanding the basal ganglia–thalamic–cor... system, particularly in the context of movement disorders such as Parkinson’s disease. Despite significant therapeutic advances, current dopamine replacement and Deep Brain Stimulation therapies remain limited due to incomplete and oversimplified prevailing theories. This reference provides a comprehensive alternative approach grounded in complexity science, nonlinear dynamics, and chaotic systems theory.The book's contents span foundational concepts, including motor unit orchestration, networked nonlinear oscillators, information theory, and methodological considerations. Detailed chapters cover the shortcomings of current models, the application of chaotic system mathematics to basal ganglia physiology, and the implications for pathophysiology and treatment. The book also includes extensive simulations, operational hypotheses, and a rigorous critique of existing paradigms that is supported by principles such as Causational and Informational Synonymy.

  • Autophagy – Part C

    • 1st Edition
    • Volume 406
    • English
    Autophagy trilogy, Part C dives into the mature landscape of cellular housekeeping, weaving together the mechanistic precision of modern biology with the larger questions of health, aging, and resilience. Building on the foundations laid in Parts A and B, this book takes the reader from the microscopic machinery inside a single cell to the sweeping implications for organisms, ecosystems, and medicine.

  • Hypercortisolism: Diagnosis and Differential Diagnosis

    • 1st Edition
    • Volume 132
    • English
    Hypercortisolism: Diagnosis and Differential Diagnosis, Volume 132 presents a comprehensive series of chapters focused on the various aspects of endogenous hypercortisolism as contributed by an international team of specialists in endocrinology. Chapters in this new release include Cushing´s syndrome: Clinical presentation and associated comorbidities, Biochemical diagnosis of hypercortisolism: when and how?, ACTH independent Cushing syndrome: diagnosis and etiology, Bilateral macronodular and micronodular hyperplasia: biochemical, radiological and genetic diagnosis, Differential diagnosis between endogenous Cushing´s syndrome and pseudoCushing, and much more.Additional chapters delve into Differential diagnosis of ACTH dependent Cushing´s syndrome: hormonal and radiological studies, Ectopic Cushing´s syndrome: clinical presentation and diagnosis, Cyclic Cushing´s syndrome, Mild autonomous cortisol secretion: diagnosis, Cushing´s syndrome and pregnancy: clinical presentation and diagnosis, Molecular profile of Cushing´s syndrome, Cardiometabolic comorbidities in overt Cushing´s syndrome, and New tools for the diagnosis of hypercortisolism.

  • Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants

    • 1st Edition
    • Volume 118
    • English
    Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants, Volume 118 in the Advances in Botanical Research series, presents interesting chapters on a variety of topics, including Silicon in Soil and Plant, Silicon Transporters in Agronomic Crops, The Role of Silicon in Sustainable Disease Management of Monocot Plants, Silicon in the Management of Diseases in Dicot Crops, Silicon and Biocontrol Agents for Plant Growth and Control of Diseases in Rice, Silicon for the Control of Insect Herbivores in Agronomic Crops, Silicon-Driven Phenotypic Induction Enhances Physiological Tolerance to Water Deficit and Waterlogging in Agronomic Crops, and much more.Additional sections cover Silicon Nutrition for Sugarcane Production, Silicon Nutrition of Agronomic Crops, Physiological Aspects of Silicon in Plants under Stress, and Alleviation of Heavy Metal Stress in Plants by Silicon.

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