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Academic Press

  • Mitochondrial Intoxication

    • 2nd Edition
    • Marcos Roberto de Oliveira
    • English
    Mitochondrial Intoxication, Second Edition, offers a comprehensive and fully updated exploration of the impact of toxic molecules on mitochondrial physiology and the diseases that result from their dysfunction. Divided into three sections, the book opens with a detailed overview of mitochondrial physiology, molecular markers of mitochondrial intoxication, and challenges of mitochondrial profiling during pre-clinical studies. The book then focuses on endogenous toxicants and their impact on mitochondria, including new chapters on lipids, glucose and microbiota-derived toxicants. Amyloid-β peptide and its impact on mitochondrial dysfunction is also a new addition to this book, as well as inflammation-induced mitochondrial intoxication.The final section explores exogenous toxicants, such as pollutants, food additives, illicit and pharmaceutical drugs, pesticides, and heavy metals. The effects of micro- and nanoplastics on mitochondrial function are newly covered. Furthermore, the latest computational tools in mitochondrial toxicity research are investigated. Incorporating the latest advances in the field, this new release offers cutting-edge insights on mitochondrial toxicity, serving as an invaluable resource for researchers and advanced students in cell biology, molecular biology, toxicology, biochemistry, pharmacology, and related fields.
  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 118
    • English
    Annual Reports on NMR Spectroscopy, Volume 117 presents the latest release in a series that has been at the vanguard of reviewing the magnetic resonance literature. The book covers magnetic resonance in all its forms, including theory, experiment, applications, and interconnections with other techniques. It also provides the opportunity to make coherent aspects of magnetic resonance that were scattered and opaque. Historical articles are also welcomed. The main topic covered in this release includes The use of NMR spectroscopy in peptide sequencing.
  • Up and Running with AutoCAD 2027

    2D and 3D Drawing, Design and Modeling
    • 1st Edition
    • Robert C. Kaebisch + 1 more
    • English
    Up and Running with AutoCAD® 2027: 2D and 3D Drawing, Design and Modeling presents a combination of step-by-step instructions, examples, and insightful explanations. The book emphasizes core concepts and practical application of AutoCAD in engineering, architecture, and design. To improve student learning, the book's early chapters have been revised and expanded with additional assignments, more explicit step-by-step guidance for the earliest assignments, improved readability, and a new concise drafting fundamentals reference section that focuses on orthographic projection, basic standards, and naming conventions.Equally useful in instructor-led classroom training, self-study, or as a professional reference, the book is written by a long-time AutoCAD professor and instructor with the user in mind
  • Advances in Structural Biology

    Applications in Protein Structure, Function, and Disease
    • 1st Edition
    • Anas Shamsi + 3 more
    • English
    Advances in Structural Biology: From Protein Structures to Function and Disease offers a comprehensive, practical resource that bridges the latest experimental and computational approaches in structural biology. Backed by real-world case studies, the book demonstrates how these technologies can be utilized to serve a range of biological needs. The content spans foundational principles of protein structure and bioinformatics tools, cutting-edge methodologies such as MicroED and Cryo-EM, and the transformative role of artificial intelligence and big data analytics in structural biology. It also considers applications including drug discovery, vaccine development, antiviral therapy, personalized medicine, and the structural basis of aging and neurodegenerative diseases.Readers will find detailed investigation into the latest developments in structural and computational biology, including insights into integrative methodologies that combine both traditional and emerging technologies. This resource is invaluable for advanced students, researchers, and professionals aiming to harness structural biology for innovative solutions in precision medicine and translational research.
  • Histone Deacetylases in Neurodegenerative Disease Part A

    • 1st Edition
    • Volume 733
    • English
    Histone Deacetylases in Neurodegenerative Disease, Part A, Volume 733 in the Methods in Enzymology series, highlights new advances, with this volume presenting chapters on topics such as HDAC Inhibitor-Induced Endoplasmic Reticulum (ER) Stress, Specific activation of p300/CBP Lysine acetyltransferases induces adult neurogenesis and synaptic plasticity, Chromatin immunoprecipitation assay for analyzing histone H3-mediated regulation of copper homeostasis, Histone Deacetylase 6 modulates Tau structure and function, Histone Acetylation in Parkinson Disease, DNA methylation and histone modification in hypoxic conditions, The extracellular Histone Deacetylase 6 modulates the actin networks in neuronal cells, Epigenetic modulators as therapeutics for neurodegenerative disorder/Alzheimer's disease, and much more.Additional chapters explore Sirtunins in mitochondrial physiology and energy homeostasis, Sirtunins in metabolic homeostasis, Conformational flexibility of histone variant CENP-ACse4 is regulated by histone H4: A mechanism to stabilize soluble Cse4, Analysis of copper toxicity by western blotting of secretory proteins translocated via Sec61 channel, Histone deacetylase as a potential therapeutic target for memory disorders, Histone deacetylases in Neurodegeneration, Role of Deubiquitinases in Regulating Tau Acetylation and Autophagic Clearance in Alzheimer’s Disease, Histone deacetylases in Neurodegeneration and neuronal plasticity, and more.
  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 121
    • English
    Advances in Food and Nutrition Research, Volume 121 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Precision nutrition in autoimmune diseases, Current and novel food allergens: cross-reactivity and cross-sensitization risks, Microbiota, fermentation, and metabolite biotransformation: pathways to functional foods and personalized nutrition, Pectins and Modified Pectins: Bridging Food Technology and Human Health Innovations, Methodological Approaches to Assess Protein Digestibility with an Emphasis on Plant-Derived Foods, Recent advances in natural melanin added food packaging, and much more.Additional sections cover A comprehensive overview of the formation of biogenic amines in seafood, Microplastics as an unexplored emerging food contaminant: a challenge for food safety, and Animal-origin food waste hydrolysates for its use as a food/feed ingredient.
  • Intelligent Gene Editing in Plants

    The Convergence of AI and CRISPR
    • 1st Edition
    • Aftab Ahmad + 3 more
    • English
    Intelligent Gene Editing in Plants analyzes how AI-enabled design and CRISPR-based genome engineering are reshaping plant genetics, with a clear functional focus on delivering durable gains in crop productivity, stress tolerance, and nutritional quality.The work unfolds in three parts: [i] a foundational survey of genome-editing technologies and the evolving role of AI in precise trait modifications and outcome prediction; [ii] a thorough exploration of applications and synergies, including AI-assisted gRNA optimization, off-target mitigation, regulatory-network analysis, and trait enhancement for disease resistance and climate resilience; and [iii] an emerging-horizons section on cis-regulatory edits, omics integration, synthetic biology, and next-generation editing.Throughout, the volume interweaves practical experiences, cutting-edge methodologies, and case studies, alongside discussions of biosafety, ethical concerns, governance, and public perception, providing a holistic, decision-ready resource for students, researchers, practitioners, and regulatory authorities to navigate the opportunities and responsibilities of plant gene editing, with significant implications for sustainable agriculture and global food security.
  • Methods in Chemical Process Safety

    • 1st Edition
    • Volume 10
    • English
    Method of Process Systems in Energy Systems, Volume Ten, the latest release in the Methods in Chemical Process Safety series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Introduction to Safety Culture, Fundamentals and Foundation Principles of a Resilient Safety Culture, The Role of Safety Culture in Several CSB Investigations, Safety Driven by Internal Values: Compliance to Commitment, Safety Training, Incident Investigation and Learning Lessons, Case Studies I, Case Studies II, Assessing Safety Culture Score, Diagnosing Safety Culture Story Behind the Score, and much more.Additional chapters cover Innovation in Enhancing Safety Culture: AI, Automation and Digitalization, Ethics in AI-Driven Safety Culture, Integrating Global and Cultural Dimensions into Safety Practices, and The Role of Sustainability in Evolving Safety Culture.
  • The Honey Bee and Climate Change

    • 1st Edition
    • Gloria DeGrandi-Hoffman
    • English
    A honey bee colony is a community of interacting organisms continually adjusting their behaviors, both individually and collectively, in response to even the subtlest changes in the environment. It’s only logical then, that the more significant changes and stressors due to climate change will push the colony to its limits, disrupting the delicate balance of the hive and threatening the survival of the colony. Honey Bees and Climate Change is the first and only book to examine the responses of honey bees to climate change and the threat it poses to their ability to thrive and survive. Drawing on systems science and the central theme that all outcomes are products of an interconnected system, the book will address how climate change is affecting honey bee nutrition, growth, and overwinter survival, which in turn threaten commercial beekeeping and crop production. Impacts on other pollinators will be touched on as well. Finally, potential mitigating strategies, key areas of action, and the future outlook will be covered.Written by a leading scientist with over 40 years of experience studying honey bee physiology, nutrition, colony survival, and the impact of climate change on the colony, Honey Bees and Climate Change is crucial reading for students and researchers studying honey bees, especially those with an interest in the impacts of climate change on pollinators. The inclusion of key terms and definitions as well as case studies make this work an excellent supplementary text for courses on honey bee biology, apiculture, pollinator conservation, or climate change ecology.
  • The Economics of News Media

    • 1st Edition
    • Sangwoo Yang
    • English
    The Economics of News Media examines the economic underpinnings that shape news media, providing a comprehensive introduction to the field of news media economics that bridges the gap between economics, media studies, and journalism. Each chapter delves into critical topics, from the structure of news markets to the implications of media bias, competition, and evolving news landscapes in the digital age. By offering empirical studies and theoretical insights, this work not only addresses the needs of researchers and students, but also provides practical tools for professionals grappling with the economic dynamics of news media.This is an essential resource for anyone hoping to understand the economic complexities underpinning the news landscape. With clear explanations and rich, global examples, the book offers practical knowledge and approaches to navigate the multifaceted issues of misinformation, media power, and democratic accountability in today’s media environment.