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Elsevier

Academic Press

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • Applying Artificial Intelligence to Computational Biology and Medical Informatics

    • 1st Edition
    • Mohammad Sufian Badar
    • English
    Applying Artificial Intelligence to Computational Biology and Medical Informatics explores the transformative role of AI and machine learning in modern biomedical research and healthcare. The book covers foundational concepts in AI/ML, computational biology, and medical informatics, followed by in-depth chapters on medical imaging, network biology, chemoinformatics, and public health. Other sections address ethical and societal implications, interpretable AI, and real-world case studies, making complex topics accessible through clear language and structured content. Designed for early-career researchers, students, and professionals without prior expertise in computer science or health sciences, this book provides a progressive learning path from basic to intermediate levels.Readers benefit from practical examples, online resources, and a coherent chapter structure that supports both academic study and applied research.

  • Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery

    A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones
    • 1st Edition
    • Oktay Ozman + 1 more
    • English
    Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery: A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones is the ultimate resource for healthcare professionals seeking to excel in the field of kidney stone surgery. The book provides a comparative history of RIRS and PCNL, exploring their evolution from early attempts at endoscopic stone removal to the development of flexible ureteroscopy and technique refinement. It covers instrumentation, including access sheaths, ureteroscopes, energy sources, and fluoroscopy. Patient selection criteria, anesthesia techniques, and intraoperative monitoring are thoroughly examined.The book offers detailed guidance on kidney access, including transureteral and percutaneous approaches, and discusses fragmentation and stone retrieval methods, comparing their efficacy and outcomes. Complications, management strategies, postoperative care, and long-term outcomes assessment are extensively discussed, ensuring a comprehensive understanding of patient care. With its comprehensive coverage and contributions from renowned experts, the book equips healthcare professionals with the knowledge and skills needed to excel in the rapidly evolving field of minimally invasive kidney stone management.

  • Handbook of the Psychology of Aging

    • 10th Edition
    • Denis Gerstorf + 1 more
    • English
    Handbook of the Psychology of Aging, Tenth Edition offers insights into emerging areas of research and practice in the field of aging. In addition to its comprehensive coverage of traditional topics such as cognitive aging and social dynamics, this edition highlights key contemporary issues. New to this edition are chapters dedicated to the understanding of emotion and stress regulation in older adults, the intricate relationship between technology and aging, the evolving landscape of work and retirement, and alternative age markers beyond chronological age. As with previous editions, this handbook remains committed to bridging the gap between theory and practice, offering evidence-based strategies.With its multidisciplinary perspective and practical insights, it continues to serve as an indispensable resource for researchers, practitioners, and students across various disciplines, from psychology and gerontology to public health and social work.

  • Advanced Cancer Therapeutics

    Strategies and Technologies for Targeted Drug Delivery
    • 1st Edition
    • Manish Kumar + 2 more
    • English
    Advanced Cancer Therapeutics: Strategies and Technologies for Targeted Drug Delivery explores the heterogeneity of tumors and microenvironmental factors that influence cancer treatment and contribute to drug resistance. The book discusses critical elements such as tumor stroma, vasculature, pH, hypoxia, and enzymatic activity that impact therapeutic efficacy. Sections cover advanced drug formulations, including supramolecular systems, metal-organic frameworks, and nanomedicine, focusing on their roles in selective drug delivery for early detection, diagnosis, and treatment of various cancers. In addition, it reviews the current status and future perspectives of these formulations, highlighting their potential to enhance therapeutic outcomes while minimizing side effects.Readers will also find discussions on the limitations of nanocarriers, along with regulatory and ethical considerations related to anticancer formulations. This resource is invaluable for researchers, clinicians, and students, offering insights into the latest advancements in drug delivery systems.

  • Microbial Exopolysaccharides

    An Integrated Approach to Green Applications
    • 1st Edition
    • Onkar Nath Tiwari + 2 more
    • English
    Microbial Exopolysaccharides: An Integrated Approach to Green Applications provides a comprehensive overview of natural exopolysaccharides (EPS) obtained from different microbial species and marine resources. Featuring contributions by an interdisciplinary group of experts in academia, research, and industry, this book offers a detailed introduction and exploration of natural microbial exopolysaccharides. It offers detailed discussions on topics such as the extraction and characterization of EPS, their role in health-promoting formulations and probiotic potential, their utilization in therapeutics, their use in food technologies and packaging, and their impact in the environmental and medical sectors.The book offers in-depth insights into the principles of EPS and their wide range of applications as sustainable solutions to challenges in the food, health, environmental, and biotechnology sectors.With a focus on green technology and sustainable practices, this book offers cost-effective utilization of natural EPS, their application in diverse sectors, and serves as an informative resource for those interested in the innovative application of natural bio-macromolecules.

  • Cyclodextrin Glucanotransferase

    A Comprehensive Guide from Gene to Applications
    • 1st Edition
    • Kiransinh Rajput
    • English
    Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role of cyclodextrin glucanotransferase (CGTase) in starch degradation and its diverse industrial applications. This book serves as a valuable resource for researchers and industry professionals, offering comprehensive insights from the genetic basis of CGTase to its practical applications. The book covers the production of CGTase by different bacterial genera, including Bacillus spp., and their purification strategies. It delves into the structural and functional characteristics of CGTase, highlighting its catalytic mechanisms, substrate specificity, and factors affecting enzyme activity and stability. Additionally, the book explores recombinant CGTases, their properties, and advancements in protein engineering and enzyme immobilization. With a strong focus on practical applications, the book discusses the remarkable properties of cyclodextrins, such as inclusion complex formation, and their wide range of uses in various industries, including pharmaceuticals, textiles, bioremediation, and food. Detailed case studies and real-world examples illustrate how CGTase and cyclodextrins can address specific challenges and drive innovation in these fields.This book is an essential resource for applied science researchers working in the field of starch processing enzymes, providing them with the knowledge to advance their research and development. It also serves as a valuable reference for researchers in the starch processing industries, offering insights into the latest advancements and practical applications of CGTase and cyclodextrins.

  • Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine

    Education of the Novel Medical Approaches in Daily Clinical Practice
    • 1st Edition
    • Artur Rydosz + 2 more
    • English
    Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine: Education of the Novel Medical Approaches in Daily Clinical Practice leverages cutting-edge technologies and innovative methodologies, such as 3D medical imaging, functional data analysis, and advanced educational frameworks to enhance clinical practice, medical research, and professional development in healthcare. Readers will learn to utilize enhanced diagnostic skills, discover how to implement immersive technologies into clinical workflows, and access resources for professional development, empowering them to stay current with advancements and elevate their clinical practice.Written by experts in the field for practicing clinicians, surgeons, and radiologists specializing in cardiology and cardiovascular medicine, as well as medical researchers and educators who are actively integrating advanced multimodal medical technologies into clinical diagnostics, treatment planning, and procedural training, this book provides an ideal reference for professional development in healthcare.

  • Pharmacological Foundations of Parkinson’s Disease

    From Mechanisms to Clinical Practice
    • 1st Edition
    • Wael Mohamed
    • English
    Pharmacological Foundations of Parkinson's Disease: From Mechanisms to Clinical Practice provides a comprehensive guide on the pharmacological treatment of Parkinson's Disease, offering students and clinicians a combination of foundational knowledge and advanced clinical insights. The book bridges theoretical concepts with real-world clinical scenarios and equips readers with the tools necessary to effectively manage Parkinson's Disease in practice. Offering a detailed review of symptoms, treatment gaps, and emerging therapies, this book delves into the pathogenesis the disease, along with dopaminergic treatments and management of motor and non-motor symptoms.Providing updates on emerging therapies, including innovative treatment approaches, this book serves as a valuable reference for continuous learning and staying current with evolving practices and research in Parkinson's Disease management.

  • Microglial Advances in Neurodegenerative Diseases

    • 1st Edition
    • Volume 171
    • English
    Microglial Advances in Neurodegenerative Diseases, Volume 170 in the Advances in Immunology series, presents current developments and comprehensive reviews focused on the role of microglia and neuroinflammation in neurological and psychiatric disorders. This volume brings together contributions from leading researchers, offering up-to-date insights into microglial biology in health and disease, as well as their involvement in major neurodegenerative conditions. Chapters in this new release explore Cross-talk between Tau and Neuro-glia Axis of Alzheimer’s Disease, Microglia in Health and Disease, Amyloid-beta (Aβ) and Neuroinflammation in Microglia, Chemokine Receptor CX3CR1 Interacts with Tau and Regulates Microglial Activity in Alzheimer’s Disease, and much more.Additional chapters explore Human-Induced Pluripotent Stem Cells in Psychiatric Disorders, GPCR-Mediated Internalization and Endosomal Sorting of the Tau–GPCR Complex in Microglia, iPSC-Derived Microglia: A Cellular Platform for Tau and Alzheimer’s Disease Immunotherapy, Advancements in Invasive and Non-Invasive Neuromodulation for Parkinson’s Disease, LRRK2-I1371V Disrupts Microglial Membrane Homeostasis and Enhances α-Synuclein Toxicity, Microglial Advances in Parkinson’s Disease, Microglial Advances in Alzheimer’s Disease, and more.

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