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Elsevier

Academic Press

  • The Dual Role of Inflammation in Cancer

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    The Dual Role of Inflammation in Cancer Genesis and Therapy explores the pivotal role inflammation plays in the development and progression of cancer. The book delves into how chronic inflammation creates a microenvironment that supports tumor growth by promoting cellular proliferation, survival, and migration while suppressing immune responses. It traces historical observations, linking inflammation to cancer while also examining how inflammatory cells and mediators contribute to various stages of tumorigenesis. In addition, it discusses the implications of inflammation on cancer treatment, highlighting the potential of anti-inflammatory agents and immunotherapy in targeting the inflammatory tumor microenvironment.By elucidating on the intricate relationship between inflammation and cancer, the book aims to pave the way for more effective and personalized cancer treatment strategies. As such, it is a valuable resource for researchers in immunology and oncology.

  • Microbial Exopolysaccharides

    An Integrated Approach to Green Applications
    • 1st Edition
    • Onkar Nath Tiwari + 2 more
    • English
    Microbial Exopolysaccharides: An Integrated Approach to Green Applications provides a comprehensive overview of natural exopolysaccharides (EPS) obtained from different microbial species and marine resources. Featuring contributions by an interdisciplinary group of experts in academia, research, and industry, this book offers a detailed introduction and exploration of natural microbial exopolysaccharides. It offers detailed discussions on topics such as the extraction and characterization of EPS, their role in health-promoting formulations and probiotic potential, their utilization in therapeutics, their use in food technologies and packaging, and their impact in the environmental and medical sectors.The book offers in-depth insights into the principles of EPS and their wide range of applications as sustainable solutions to challenges in the food, health, environmental, and biotechnology sectors.With a focus on green technology and sustainable practices, this book offers cost-effective utilization of natural EPS, their application in diverse sectors, and serves as an informative resource for those interested in the innovative application of natural bio-macromolecules.

  • Cyclodextrin Glucanotransferase

    A Comprehensive Guide from Gene to Applications
    • 1st Edition
    • Kiransinh Rajput
    • English
    Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role of cyclodextrin glucanotransferase (CGTase) in starch degradation and its diverse industrial applications. This book serves as a valuable resource for researchers and industry professionals, offering comprehensive insights from the genetic basis of CGTase to its practical applications. The book covers the production of CGTase by different bacterial genera, including Bacillus spp., and their purification strategies. It delves into the structural and functional characteristics of CGTase, highlighting its catalytic mechanisms, substrate specificity, and factors affecting enzyme activity and stability. Additionally, the book explores recombinant CGTases, their properties, and advancements in protein engineering and enzyme immobilization. With a strong focus on practical applications, the book discusses the remarkable properties of cyclodextrins, such as inclusion complex formation, and their wide range of uses in various industries, including pharmaceuticals, textiles, bioremediation, and food. Detailed case studies and real-world examples illustrate how CGTase and cyclodextrins can address specific challenges and drive innovation in these fields.This book is an essential resource for applied science researchers working in the field of starch processing enzymes, providing them with the knowledge to advance their research and development. It also serves as a valuable reference for researchers in the starch processing industries, offering insights into the latest advancements and practical applications of CGTase and cyclodextrins.

  • New Insights in Pediatric Holter Monitoring and Interpretation

    • 1st Edition
    • Gabriel Cismaru + 2 more
    • English
    New Insights in Pediatric Holter Monitoring and Interpretation is the cutting edge book required by pediatric cardiologists and other professionals who encounter arrhythmias in children. Holter ECG examination has recently undergone significant advances in technology, sensors, and software. Yet, these innovations have been considered primarily in the context of adult patients. On the contrary, New Insights in Pediatric Holter Monitoring and Interpretation uses a case-based methodology to illustrate diagnosis and management of actual pediatric patients. Further, it offers guidance in deciding when referrals are necessary for arrhythmological consultations or ablation interventions. This book also contains novel techniques for detecting and interpreting pediatric arrhythmias. These include the introduction of Poincare graphs, Lorenz plots, and other advanced methods for assessing heart rate variability. New Insights in Pediatric Holter Monitoring and Interpretation modernizes readers' understanding of arrhythmias in children, thus improving the young lives of those in their care.

  • Cardiopulmonary Interactions in Sleep

    Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing
    • 1st Edition
    • Kyriakos Dimitriadis + 1 more
    • English
    Cardiopulmonary Interactions in Sleep: Comprehensive Approaches to Mitral Regurgitation and Sleep-Disordered Breathing delves into the correlation between these two serious conditions. Commonly found in patients with cardiovascular disease and heart failure, the interplay between mitral regurgitation and sleep-disordered breathing creates a vicious cycle of clinical deterioration. Their coexistence not only exacerbates disease severity but also increases mortality and adverse cardiovascular outcomes. This book addresses a significant gap in research by exploring this connection and offering insights into diagnosis and treatment.In addition to covering the diagnosis of these conditions, the book discusses coexistent pathologies such as arrhythmias and heart failure. It is the first to focus on the effects of surgical and transcatheter techniques on sleep-disordered breathing. The positive impact of these interventions on sleep respiration and the resulting benefits for mitral valve repair are meticulously analyzed, making it a valuable resource for understanding and treating these interconnected conditions.

  • AI-Driven Cybersecurity for Intelligent Healthcare Systems

    • 1st Edition
    • Balamurugan Balusamy + 3 more
    • English
    AI-Driven Cybersecurity for Intelligent Healthcare Systems explores the intersection between AI, cybersecurity, and healthcare. The book offers detailed insights into the unique cybersecurity challenges faced by the healthcare sector and the role of AI in addressing these challenges. It presents case studies and real-world applications to illustrate the effectiveness of these solutions and highlights the significance of data privacy in healthcare and methods to ensure secure data sharing and storage. Topics such as federated learning, homomorphic encryption, and blockchain technology are covered to demonstrate how AI can enhance data security without compromising patient privacy.This book will be an essential resource for anyone involved in the healthcare industry, offering practical solutions and fostering a more in-depth understanding of how AI can revolutionize cybersecurity in healthcare.

  • Electromagnetic Signal and Information Theory

    From Synergizing Three Realms to Evolution of Next Generation Communications
    • 1st Edition
    • Aryan Kaushik + 1 more
    • English
    Electromagnetic Signal and Information Theory: From Synergizing Two Realms to Evolution of Next Generation Communications delivers an in-depth exploration of both foundational concepts and cutting-edge innovations within wireless communications. This authoritative volume presents a seamless blend of theory, practical application, and emerging technologies, specifically tailored for university researchers and industry professionals. Readers will benefit from expert contributions that illuminate topics such as reconfigurable intelligent surfaces and holographic MIMO, addressing the growing needs for higher data rates, robust reliability, and adaptability in the evolving landscape of 5G-Advanced and 6G networks.In addition to its comprehensive technical insights, the book stands out for its thorough coverage of standardization efforts and future research directions, equipping readers to anticipate and respond to technological advancements. The interdisciplinary approach of Electromagnetic Signal and Information Theory (ESIT) is highlighted, integrating deterministic electromagnetic wave theory, statistical information theory, and advanced signal processing.

  • Biosimilars and Biologics in Cancer Treatment

    An Era in Therapeutic Strategies
    • 1st Edition
    • Kuttiappan Anitha + 2 more
    • English
    Biosimilars and Biologics in Cancer Therapy: An Era in Therapeutic Strategies addresses challenges and opportunities in biosimilars and biologics, integrating the latest evidence, regulatory landscapes, economic implications, and strategies to enhance cancer management. The book aims to create an all-inclusive educational resource, bridge the gap between research and clinical practice, and inspire future research in oncology. It provides a comprehensive examination of cancer therapeutics, starting with an introduction to biologics and biosimilars, their historical development, and foundational principles. Sections explain mechanisms of action, drug development processes, regulatory landscapes, and clinical applications through case studies. Emerging therapeutic strategies, including combination therapies and personalized medicine, are also covered. This book benefits researchers, oncologists, pharmacologists, pathologists, and other healthcare professionals by offering up-to-date insights into the clinical aspects of biological medications and their biosimilars. Contributions from global experts ensure readers gain the latest advancements and practical guidance on integrating these therapies into clinical practice and research.

  • Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine

    Education of the Novel Medical Approaches in Daily Clinical Practice
    • 1st Edition
    • Artur Rydosz + 2 more
    • English
    Functional and Virtual Medical 3D Imaging in Cardiovascular Medicine: Education of the Novel Medical Approaches in Daily Clinical Practice leverages cutting-edge technologies and innovative methodologies, such as 3D medical imaging, functional data analysis, and advanced educational frameworks to enhance clinical practice, medical research, and professional development in healthcare. Readers will learn to utilize enhanced diagnostic skills, discover how to implement immersive technologies into clinical workflows, and access resources for professional development, empowering them to stay current with advancements and elevate their clinical practice.Written by experts in the field for practicing clinicians, surgeons, and radiologists specializing in cardiology and cardiovascular medicine, as well as medical researchers and educators who are actively integrating advanced multimodal medical technologies into clinical diagnostics, treatment planning, and procedural training, this book provides an ideal reference for professional development in healthcare.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

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