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Academic Press

  • Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications

    • 1st Edition
    • May 1, 2026
    • Arun Kumar + 2 more
    • English
    Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.

  • Autophagy – Part B

    • 1st Edition
    • Volume 404
    • May 1, 2026
    • English
    Autophagy Part B provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.

  • Cardiometabolic Dynamics

    A Deep Dive into Health and Disease
    • 1st Edition
    • May 1, 2026
    • Yihua Bei + 1 more
    • English
    Cardiometabolic Dynamics: A Deep Dive into Health and Disease explores the intricate relationship between metabolic health and cardiovascular diseases, illuminating how cellular and molecular mechanisms contribute to metabolic dysregulation. The book delves into the ways metabolic pathologies act as precursors to cardiovascular conditions, including hypertension, atherosclerosis, cardiomyopathy, and heart failure. With a focus on healthy cardiometabolic dynamics, it underscores the crucial role they play in sustaining cardiovascular wellness, offering a comprehensive perspective on the intersection of metabolism and heart health.The book further examines the influence of lifestyle factors, such as diet and exercise on cardiovascular metabolism and highlights emerging technologies like omics, genetic engineering, and wearable devices to advance research, diagnosis, and treatment.

  • Inflammation and Cancer

    Mechanisms, Diagnosis, and Therapeutic Strategies
    • 1st Edition
    • May 1, 2026
    • Anoop Kumar + 4 more
    • English
    Inflammation and Cancer: Mechanisms, Diagnosis, and Therapeutic Strategies delves into the intricate relationship between inflammation and cancer, a crucial area of contemporary biomedical research. Sections provide an overview of inflammation's role in cancer, discussing molecular connections and signaling pathways. Chapters explore inflammatory pathways in various cancers, including breast, oral, lung, prostate, skin, and gastrointestinal cancers. The book also covers tumorigenesis, metastasis, preventive strategies, inflammatory biomarkers for cancer diagnosis, and innovative therapeutic designs. Final chapters focus on the dual role of platelets, targeting tumor-associated macrophages, novel treatment approaches, and recent advances in the field.This title offers substantial benefits to researchers, clinicians, and healthcare professionals by providing a thorough understanding of the cellular and molecular pathways linking inflammation and cancer, aiding in the development of effective anti-cancer immunotherapies. By highlighting the latest research and potential therapeutic strategies, this book serves as an essential resource for anyone dedicated to combating cancer through innovative and informed immunotherapeutic approaches.

  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1st Edition
    • Volume 188
    • May 1, 2026
    • English
    Gaming and Internet Addiction, Volume 188 in the International Review of Neurobiology series, presents the latest research on the neural, psychological, and clinical dimensions of excessive online behavior. This comprehensive volume brings together an international team of experts to explore the neurobiological features of internet gaming disorder and related conditions, including impulsivity, craving, and risky decision-making. Chapters detail topics such as the Neurobiological Features of Internet Gaming Disorder and Other Internet Use Disorders, Risky Decision-Making in Internet Use Disorders, Impulsivity in Internet Gaming Disorder, Psychological Interventions and Treatments for Internet Use Disorders, and much more.Additional sections cover Pharmacological and Non-Pharmacological Treatment of Internet Gaming Disorder: Functional Brain Changes and Factors Associated with Treatment-Seeking, Craving Behavioral Interventions for Internet Gaming Disorder, Gender-Related Differences in Internet Use Disorders and Implications for Assessment and Treatment, Assessment Tools for Gaming Disorder: Psychometric Foundations and Neurobiological Applications, and Machine Learning Approaches to Predict Internet Gaming Disorder and Internet Use Disorders.

  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1st Edition
    • May 1, 2026
    • Arpad Szallasi
    • English
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1st Edition
    • May 1, 2026
    • Simone Carradori + 2 more
    • English
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    • 1st Edition
    • Volume 169
    • May 1, 2026
    • English
    Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications, Volume 169 in the Advances in Immunology series, presents an authoritative exploration on how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers. Chapters highlight The Microbiome of the Head and Neck Region, Overview Head and Neck Microbiota and the Factors Influencing the Head and Neck Microbiome, Mechanistic Pathways of Dysbiosis in Cancer Development, Oral Microbiota and OPMDs, Oral Potentially Malignant Disorders (OPMDs): An Overview, Oral Microbiota and Oral Cancer, Oral Squamous Cell Carcinoma (OSCC): An Overview, and much more.Additional chapters cover the Role of the Oral Microbiome in Oral Cancer (OSCC), Microbiome as a Prognostic Indicator in Oral Cancer, Diagnostic and Therapeutic Applications, Microbiome-Based Diagnostic Approaches, Modulating the Head and Neck Microbiome for Cancer Prevention, Microbiome-Targeted Therapeutics in Head and Neck Cancer, Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer, and Challenges and Future Directions in Head & Neck Microbiome Research.

  • Molecular Mechanisms of Spermatogenesis

    • 1st Edition
    • Volume 168
    • May 1, 2026
    • English
    Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.

  • Minimally Invasive Spine Techniques

    Modern Approaches
    • 1st Edition
    • May 1, 2026
    • Timothy R. Deer + 1 more
    • English
    Minimally Invasive Spine Techniques: Modern Approaches is an indispensable resource tailored for practitioners facing the daily challenges demanding precision, innovation, and comprehensive knowledge. This edited reference not only provides a detailed exploration of anatomy critical to procedural success but also equips practitioners with the latest techniques and tools in minimally- invasive surgery (MIS). From patient selection criteria to surgical techniques and device applications, this atlas ensures that every facet of device implantation is approached with the highest standards of care and innovation.Richly illustrated with a pictorial atlas of best practices, it serves as an essential guide for training, ensuring optimal outcomes in clinical practice.

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