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    • Second Generation Cell and Gene-Based Therapies

      • 1st Edition
      • February 7, 2020
      • Alain Vertes + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 2 0 3 4 7
      • eBook
        9 7 8 0 1 2 8 1 2 0 3 3 0
      Second Generation Cell and Gene-Based Therapies: Biological Advances, Clinical Outcomes, and Strategies for Capitalisation serves as the only volume to the market to bridge basic science, clinical therapy, technology development, and business in the field of cellular therapy/cytotherapy. After more than two decades of painstaking fundamental research, the concept of therapeutic cells (stem cells, genes, etc.), beyond the concept of vaccines, is reaching clinical trial, with mounting confidence in the safety and efficacy of these products. Nonetheless, numerous incremental technical advances remain to be achieved. Thus, this volume highlights the possible R&D paths, which will ultimately facilitate clinical delivery of cutting edge curative products.The next waves of innovation are reviewed in depth for hematopoietic stem cells, mesenchymal stem cells, tissue engineering, CAR-T cells, and cells of the immune system, as well as for enabling technologies such as gene and genome editing. Additionally, deep dives in product fundamentals, history of science, pathobiology of diseases, scientific and technological bases, and financing and technology adoption constraints are taken to unravel what will shape the cytotherapy industry to the horizon 2025 and beyond. The outcome is not simply a scientific book, but a global perspective on the nascent field combining science, business, and strategic fundamentals.

    • Matrix Methods

      • 4th Edition
      • February 5, 2020
      • Richard Bronson + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 4 1 9 6
      • eBook
        9 7 8 0 1 2 8 1 8 4 2 0 2
      Matrix Methods: Applied Linear Algebra and Sabermetrics, Fourth Edition, provides a unique and comprehensive balance between the theory and computation of matrices. Rapid changes in technology have made this valuable overview on the application of matrices relevant not just to mathematicians, but to a broad range of other fields. Matrix methods, the essence of linear algebra, can be used to help physical scientists-- chemists, physicists, engineers, statisticians, and economists-- solve real world problems.

    • Advances in Food and Nutrition Research

      • 1st Edition
      • Volume 91
      • February 5, 2020
      • Fidel Toldra
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 4 7 0 2
      • eBook
        9 7 8 0 1 2 8 2 0 4 7 1 9
      Approx.322 pages

    • Handbook of Research on Blockchain Technology

      • 1st Edition
      • February 4, 2020
      • Saravanan Krishnan + 5 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 8 1 6 2
      • eBook
        9 7 8 0 1 2 8 2 0 4 1 5 3
      Handbook of Research on Blockchain Technology presents the latest information on the adaptation and implementation of Blockchain technologies in real world business, scientific, healthcare and biomedical applications. The book's editors present the rapid advancements in existing business models by applying Blockchain techniques. Novel architectural solutions in the deployment of Blockchain comprise the core aspects of this book. Several use cases with IoT, biomedical engineering, and smart cities are also incorporated. As Blockchain is a relatively new technology that exploits decentralized networks and is used in many sectors for reliable, cost-effective and rapid business transactions, this book is a welcomed addition on existing knowledge. Financial services, retail, insurance, logistics, supply chain, public sectors and biomedical industries are now investing in Blockchain research and technologies for their business growth. Blockchain prevents double spending in financial transactions without the need of a trusted authority or central server. It is a decentralized ledger platform that facilitates verifiable transactions between parties in a secure and smart way.

    • Prognostic and Therapeutic Applications of RKIP in Cancer

      • 1st Edition
      • February 3, 2020
      • Benjamin Bonavida + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 6 1 2 0
      • eBook
        9 7 8 0 1 2 8 2 2 4 5 1 9
      Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression in cancer open a novel era of new therapeutics and their potential in the treatment of highly resistant cancers and metastases. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students.

    • Evidence-informed Approaches for Managing Dementia Transitions

      • 1st Edition
      • February 2, 2020
      • Linda Garcia + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 5 6 6 8
      • eBook
        9 7 8 0 1 2 8 1 7 5 6 7 5
      Evidence-Informed Approaches for Managing Dementia Transitions provides evidence-informed approaches and future directions for supporting a higher quality of life for people living with dementia. Through a person-centered lens, this book equips care providers to better help people living with dementia align their expectations and hopes with the trajectories they can expect in their journey. It highlights the various transitions that those with dementia will experience and describes best practices for optimal adjustment to each. Topics covered include problem identification, driving cessation, loss of financial autonomy, acute hospital admission, moving to assisted living residences and long term care homes, and palliative and end of life care. This is a must have reference for researchers, clinicians, and mental health professionals (psychologists, counsellors, social workers, mental health nurses) as well as policy makers and other health and social care providers working with individuals with dementia.

    • Annual Reports on NMR Spectroscopy

      • 1st Edition
      • Volume 99
      • February 2, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 9 7 0 7
      • eBook
        9 7 8 0 1 2 8 2 0 9 7 1 4
      Annual Reports on NMR Spectroscopy, Volume 99, provides an in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications. Specific chapters in this new release include Recent Developments in the accurate measurement of NMR Transverse Relaxation Times, NMR Studies of the Binding and Dynamics of Ionic Liquids with Proteins, Recent Developments in 1HNMR Relaxometry, Solid State 19F NMR Studies of Oriented Peptides, and Applications of Nuclides other than 1H and 13C in Solid State NMR Studies of Pharmaceuticals.

    • Regulation of Nitrogen-Fixing Symbioses in Legumes

      • 1st Edition
      • Volume 94
      • February 1, 2020
      • English
      • Hardback
        9 7 8 0 0 8 1 0 2 7 9 8 1
      • eBook
        9 7 8 0 0 8 1 0 2 7 9 9 8
      The Nitrogen-Fixing Legume-Rhizobium Symbiosis, Volume 94, the latest release in the Advances in Botanical Research series, highlights new advances in the field, with this new volume presenting interesting chapters on The diversity of legume-rhizobium symbioses, Parasponia; an evolutionary outlier of rhizobium symbiosis, Rhizobium diversity in the light of evolution, Genomes of rhizobia, Gene regulation by extracytoplasmic function (ECF) sigma factors in alpha-rhizobia, Early symbiotic signaling between Plant and Bacteria, Rhizobia infection, a journey to the inside of plant cells, Differentiation of symbiotic nodule cells and their rhizobium endosymbionts, Nodule Organogenesis, Nitrogen Fixation by the Legume-Rhizobium Symbiosis, and much more.

    • Behind and Beyond the Meter

      • 1st Edition
      • February 1, 2020
      • Fereidoon Sioshansi
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 9 5 1 0
      • eBook
        9 7 8 0 1 2 8 2 0 4 1 4 6
      The historical ways in which electricity was generated in large central power plants and delivered to passive customers through a one-way transmission and distribution network – as everyone knows – is radically changing to one where consumers can generate, store and consume a significant portion of their energy needs energy locally. This, however, is only the first step, soon to be followed by the ability to share or trade with others using the distribution network. More exciting opportunities are possible with the increased digitalization of BTM assets, which in turn can be aggregated into large portfolios of flexible load and generation and optimized using artificial intelligence and machine learning.

    • Sustainability of the Food System

      • 1st Edition
      • January 31, 2020
      • Noelia Betoret + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 2 9 3 2
      • eBook
        9 7 8 0 1 2 8 1 8 2 9 4 9
      Sustainability of the Food System: Sovereignty, Waste, and Nutrients Bioavailability addresses the concept of global sustainability, focusing on three key areas of action within the food production system: food sovereignty, environmentally friendly food processes, and food technologies that increase the bioavailability of bioactive compounds. The book defines key concepts in the food production system and provides examples of specific and tailored actions that contribute to global sustainability. Sustainability of the Food System: Sovereignty, Waste, and Nutrients Bioavailability will serve as a welcomed resource for food scientists and technologists, agriculturists, agronomic engineers, food engineers, environmental technologists, nutritionists, and post-graduate students studying bioresource technology and sustainability.

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