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Academic Press

  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1st Edition
    • May 1, 2026
    • Arpad Szallasi
    • English
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

  • Role of Biomarkers in Cancer Diagnosis and Therapeutics

    • 1st Edition
    • May 1, 2026
    • Sushama Talegaonkar + 2 more
    • English
    Role of Biomarkers in Cancer Diagnosis and Therapeutics offers a thorough exploration of the critical roles biomarkers play in cancer detection, diagnosis, monitoring, and therapy. Sections focus on established and emerging biomarkers like PSA and CEA, detailing their biochemical characteristics and clinical relevance, and examining metabolic pathways utilized by cancer cells, highlighting key enzymes and their therapeutic potential. The final part pf the book discusses innovative strategies targeting cell cycle checkpoints and DNA repair mechanisms, including synthetic lethality through PARP inhibitors. This essential resource provides researchers and clinicians with insights into novel metabolic targets and cutting-edge treatment strategies.By addressing current applications and future challenges, including the integration of AI and multi-omics approaches, the book equips readers with actionable knowledge to advance personalized cancer care and navigate the dynamic landscape of oncology.

  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1st Edition
    • May 1, 2026
    • Simone Carradori + 2 more
    • English
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

  • Advances in Immunology

    • 1st Edition
    • Volume 168
    • May 1, 2026
    • English
    Advances in Immunology, Volume 168, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Sample topics in this new release include Alarmins in mucosal tissues and how they regulate health and disease, and more.

  • Progress in Optics

    • 1st Edition
    • Volume 71
    • May 1, 2026
    • English
    Progress in Optics, Volume 71 in this ongoing series, presents the latest release in this renowned serial publication that provides comprehensive, authoritative reviews on significant developments in the field of optical science and engineering. Chapters in this new release include updates on Phased-array lidar, Holographic metasurfaces, The Talbot effect, Space-time optics, Structured Light in Space and Time: Enabling Applications Across Linear, Nonlinear, and Quantum Domains, RIKEN Center for Advanced Photonics, Metaphotonics Research Team, Weak quantum measurements, and Structured Light.Each volume in this series brings together contributions from leading experts, covering a wide range of topics, including classical optics, quantum optics, nonlinear optics, optical materials, photonics, laser technology, imaging systems, and emerging applications.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    • 1st Edition
    • Volume 169
    • May 1, 2026
    • English
    Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications, Volume 169 in the Advances in Immunology series, presents an authoritative exploration on how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers. Chapters highlight The Microbiome of the Head and Neck Region, Overview Head and Neck Microbiota and the Factors Influencing the Head and Neck Microbiome, Mechanistic Pathways of Dysbiosis in Cancer Development, Oral Microbiota and OPMDs, Oral Potentially Malignant Disorders (OPMDs): An Overview, Oral Microbiota and Oral Cancer, Oral Squamous Cell Carcinoma (OSCC): An Overview, and much more.Additional chapters cover the Role of the Oral Microbiome in Oral Cancer (OSCC), Microbiome as a Prognostic Indicator in Oral Cancer, Diagnostic and Therapeutic Applications, Microbiome-Based Diagnostic Approaches, Modulating the Head and Neck Microbiome for Cancer Prevention, Microbiome-Targeted Therapeutics in Head and Neck Cancer, Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer, and Challenges and Future Directions in Head & Neck Microbiome Research.

  • Molecular Mechanisms of Spermatogenesis

    • 1st Edition
    • Volume 168
    • May 1, 2026
    • English
    Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.

  • Minimally Invasive Spine Techniques

    Modern Approaches
    • 1st Edition
    • May 1, 2026
    • Timothy R. Deer + 1 more
    • English
    Minimally Invasive Spine Techniques: Modern Approaches is an indispensable resource tailored for practitioners facing the daily challenges demanding precision, innovation, and comprehensive knowledge. This edited reference not only provides a detailed exploration of anatomy critical to procedural success but also equips practitioners with the latest techniques and tools in minimally- invasive surgery (MIS). From patient selection criteria to surgical techniques and device applications, this atlas ensures that every facet of device implantation is approached with the highest standards of care and innovation.Richly illustrated with a pictorial atlas of best practices, it serves as an essential guide for training, ensuring optimal outcomes in clinical practice.

  • A Quick Reference to Obstetric Anesthesia

    • 1st Edition
    • April 30, 2026
    • Adithya Devadas Bhat + 1 more
    • English
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • Approaches for Brain Targeting Using Nanoparticulate Systems

    • 1st Edition
    • April 27, 2026
    • Bhagyashree V. Salvi + 2 more
    • English
    Approaches for Brain Targeting Using Nanoparticulate Systems aims to explore variety of nanoparticulate systems in the enhancement of therapeutic delivery, promotion for effective brain targeting, and reduction in the off-targets. Presenting the latest research, this book offers comprehensive insight into various nanosystems designed to overcome the blood brain barrier. This book presents the latest research on targeting approaches, physicochemical characteristics of nanoparticles, and the role of nanoparticles in enhancing the permeation of therapeutic systems across the blood brain barrier. Readers will also be able to develop a deeper understanding of how nanotherapeutics can revolutionize brain targeting through clinical applications.

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