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    • Cellular Endocrinology in Health and Disease

      • 2nd Edition
      • February 2, 2021
      • Alfredo Ulloa-Aguirre + 1 more
      • English
      • Paperback
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      • eBook
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      Cellular Endocrinology in Health and Disease, Second Edition, describes the underlying basis of endocrine function, providing an important tool to understand the fundamentals of endocrine diseases. Delivering a comprehensive review of the basic science of endocrinology, from cell biology to human disease, this work explores and dissects the function of a number of cellular systems. The new edition provides an understanding of how endocrine glands function by integrating information resulting in biological effects on both local and systemic levels, also providing new information on the molecular physiopathogenesis of endocrine neoplasic cells. The new edition expands the most used chapters from the first edition and proposes a series of substitutions and additions to the table of contents. New chapters cover signaling, brown adipose tissue, hypothalamic cell models, cellular basis of insulin resistance, genetics and epigenetics of neuroendocrine tumors, and a series of chapters on endocrine-related cancer. Providing content that crosses disciplines, Cellular Endocrinology in Health and Disease, Second Edition, details how cellular endocrine function contributes to system physiology and mediates endocrine disorders. A methods section proves novel and useful approaches across research focus that will be attractive to medical students, residents, and specialists in the field of endocrinology, as well as to those interested in cellular regulation. Editors Alfredo Ulloa-Aguirre and Ya-Xiong Tao, experts in molecular and cellular aspects of endocrinology, deliver contributions carefully selected for relevance, impact, and clarity of expression from leading field experts

    • Synuclein and the Coelacanth

      • 1st Edition
      • January 31, 2021
      • James M. Gruschus
      • English
      • Paperback
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      • eBook
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      Most neurodegenerative diseases have animal parallels such as Alzheimer’s in chimpanzees, multiple sclerosis in macaques, Lou Gehrig’s disease in dogs, but nothing like Parkinson’s has ever been seen in any species but humans. Synuclein and the Coelacanth: The Molecular and Evolutionary Origins of Parkinson's Disease delves into the causes of Parkinson’s disease and how the evolution of the human brain has left us uniquely vulnerable. Genetic risk factors, environmental toxins, and neuroanatomy are woven together in a multidisciplinary discussion that ranges from subatomic physics to socioeconomics. Connections between neurodegenerative disease, neural pathways, and innate immunity are explored. Finally, the author discusses new therapeutic agents are being developed that hope to go beyond just treating the symptoms of Parkinson’s and actually halt the disease.

    • Recent Advances in iPSCs for Therapy

      • 1st Edition
      • January 30, 2021
      • Alexander Birbrair
      • English
      • Paperback
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      • eBook
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSCs for Therapy, Volume 3 addresses the use of induced pluripotent stem cells for therapy of several disorders. The volume teaches the reader about the biology of induced pluripotent stem cells and their possible use as cell therapy. Remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs for therapy of multiple diseases, such as: hair loss disorders, Parkinson’s disease, Huntington’s disease, ischemic stroke, Alzheimer’s disease, Glaucoma, Optic Neuropathy, Age-Related Macular Degeneration, Type 1 Diabetes, Heart Failure, liver diseases, infertility, Autoimmune Diseases, and more. The volume is written for researchers and scientists interested in cell therapy, stem cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

    • Hybrid Nuclear Energy Systems

      • 1st Edition
      • January 30, 2021
      • Michael F. Keller
      • English
      • Paperback
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      • eBook
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      Hybrid Nuclear Energy Systems: A Sustainable Solution for the 21st Century provides practical insights on the environmental impact of the hybrid systems discussed, as well as important technical, economic, licensing and safety considerations. This book acts as a guide for the implementation of hybrid energy systems and authoritatively compares the benefits and possible downfalls of each technology. This enables the reader to analyze their own setting or research and evaluate the most economical and effective solution. Energy engineering researchers and professional engineers will benefit from the practical and technical approach of this book. This book will also benefit regulators and economists who will gain a clear understanding of how a hybrid system is not only designed, but also how societies will benefit from a cleaner and more abundant energy source.

    • Experimental Hydrodynamics for Flow Around Bodies

      • 1st Edition
      • January 29, 2021
      • Viktor V. Babenko
      • English
      • Paperback
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      • eBook
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      Experimental Hydrodynamics for Flow around Bodies explains complex novel experimental methodologies to solve a wide range of important flow problems in industry and research. The book starts by examining the fundamental physical laws necessary for the optimization of techniques for hydro-aeromechanics, heat engineering, and other disciplines related to flow. The reader is then provided with detailed explanations of novel experimental methods, along with the results of physical research. These results are also necessary for the construction of theoretical models that provide improved descriptions for numerous problems in various scientific fields. Frequent discussions, examples of practical applications throughout the text, and foundational, theoretical materials help a range of readers engage and apply these methods to problems in fields including drag reduction, noiseless movement, optimal maneuvering, intense heat transfer, control of separated vortices, wind power, economical energy consumption, and more.

    • Advances in Agronomy

      • 1st Edition
      • Volume 166
      • January 29, 2021
      • Donald L. Sparks
      • English
      • Hardback
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      • eBook
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      Advances in Agronomy, Volume 166, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field. Each chapter is written by an international board of authors.

    • Mathematical Modelling of Contemporary Electricity Markets

      • 1st Edition
      • January 29, 2021
      • Athanasios Dagoumas
      • English
      • Paperback
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      • eBook
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      Mathematical Modelling of Contemporary Electricity Markets reviews major methodologies and tools to accurately analyze and forecast contemporary electricity markets in a ways that is ideal for practitioner and academic audiences. Approaches include optimization, neural networks, genetic algorithms, co-optimization, econometrics, E3 models and energy system models. The work examines how new challenges affect power market modeling, including discussions of stochastic renewables, price volatility, dynamic participation of demand, integration of storage and electric vehicles, interdependence with other commodity markets and the evolution of policy developments (market coupling processes, security of supply). Coverage addresses all major forms of electricity markets: day-ahead, forward, intraday, balancing, and capacity.

    • Aminoff's Neurology and General Medicine

      • 6th Edition
      • January 29, 2021
      • Michael J. Aminoff + 1 more
      • English
      • Hardback
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      • eBook
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      Aminoff’s Neurology and General Medicine, Sixth Edition is the standard and classic reference providing comprehensive coverage of the relationship between neurologic practice and general medicine. As neurologists are asked to consult on general medical conditions, this reference provides an authoritative tool linking general medical conditions to specific neurologic issues and disorders. This is also a valuable tool for the general practitioner seeking to understand the neurologic aspects of their medical practice. Completely revised with new chapters covering neurologic complications of immunotherapies, headache and general medical disorders, back and neck pain in general medical disorders, swallowing and speech disorders, and neurological changes in the elderly, this new edition will again be the go-to reference for both neurologists and general practitioners.

    • Nutraceuticals

      • 2nd Edition
      • January 27, 2021
      • Ramesh C. Gupta + 2 more
      • English
      • Hardback
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      • eBook
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      Nutraceuticals: Efficacy, Safety and Toxicity, Second Edition, brings together everything that is currently known about nutraceuticals and their potential toxic effects. The book introduces readers to nutraceuticals, herbal medicines, Ayurvedic medicines, prebiotics, probiotics, adaptogens, and their uses and specific applications. This essential reference discusses the mechanism of action for the judicious use of these nutraceuticals and the best tools for their evaluation before detailing the safety and toxicity of nutraceuticals and interactions with other therapeutic drugs. Finally, and crucially, regulatory aspects from around the world are covered. Completely revised and updated, this updated edition provides toxicologists, pharmacologists, pharmaceutical scientists, and those interested in medicinal plants and natural products with a comprehensive overview of the most effective tools upon which to evaluate the safety and toxicity of nutraceuticals, prebiotics, probiotics and alternative medicines.

    • Osseoconductive Surface Engineering for Orthopedic Implants

      • 1st Edition
      • January 26, 2021
      • Amirhossein Goharian
      • English
      • Paperback
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      • eBook
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      Osseoconductive Surface Engineering for Orthopedic Implants provides a comprehensive overview of the state of the art of osseointegration based on surface-mediated engineering. It offers a practical approach to the design and development of implant surface engineering, by reviewing and discussing the usability and efficacy of each processing technique. The reader can learn about the variety, characteristics, advantages, challenges, and optimum parameters for each process—enabling targeted selection of coatings and technologies to enhance long-term implant–bone integration.

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