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Academic Press

    • Vascular Disease in Women

      • 1st Edition
      • July 16, 2021
      • Caitlin Hicks + 1 more
      • English
      • Paperback
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      Vascular Disease in Women highlights the epidemiology, natural history and treatment of vascular disease, specifically as it pertains to women. The book provides a thorough overview of what is known and waht is now known about vascular disease in women and highlights opportunities for further education and research on this topic. The book will serve as an essential reference for both clinicians and researchers, discussing the disease prevalence, treatment options, and treatment outcomes for vascular disease in women and explores the need for future research in vascular disease specifically as it pertains to women.
    • Deep Learning for Chest Radiographs

      • 1st Edition
      • July 16, 2021
      • Yashvi Chandola + 3 more
      • English
      • Paperback
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      Deep Learning for Chest Radiographs enumerates different strategies implemented by the authors for designing an efficient convolution neural network-based computer-aided classification (CAC) system for binary classification of chest radiographs into "Normal" and "Pneumonia." Pneumonia is an infectious disease mostly caused by a bacteria or a virus. The prime targets of this infectious disease are children below the age of 5 and adults above the age of 65, mostly due to their poor immunity and lower rates of recovery. Globally, pneumonia has prevalent footprints and kills more children as compared to any other immunity-based disease, causing up to 15% of child deaths per year, especially in developing countries. Out of all the available imaging modalities, such as computed tomography, radiography or X-ray, magnetic resonance imaging, ultrasound, and so on, chest radiographs are most widely used for differential diagnosis between Normal and Pneumonia. In the CAC system designs implemented in this book, a total of 200 chest radiograph images consisting of 100 Normal images and 100 Pneumonia images have been used. These chest radiographs are augmented using geometric transformations, such as rotation, translation, and flipping, to increase the size of the dataset for efficient training of the Convolutional Neural Networks (CNNs). A total of 12 experiments were conducted for the binary classification of chest radiographs into Normal and Pneumonia. It also includes in-depth implementation strategies of exhaustive experimentation carried out using transfer learning-based approaches with decision fusion, deep feature extraction, feature selection, feature dimensionality reduction, and machine learning-based classifiers for implementation of end-to-end CNN-based CAC system designs, lightweight CNN-based CAC system designs, and hybrid CAC system designs for chest radiographs. This book is a valuable resource for academicians, researchers, clinicians, postgraduate and graduate students in medical imaging, CAC, computer-aided diagnosis, computer science and engineering, electrical and electronics engineering, biomedical engineering, bioinformatics, bioengineering, and professionals from the IT industry.
    • Neural Engineering Techniques for Autism Spectrum Disorder

      • 1st Edition
      • July 16, 2021
      • Ayman S. El-Baz + 1 more
      • English
      • Paperback
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      Neural Engineering for Autism Spectrum Disorder, Volume One: Imaging and Signal Analysis Techniques presents the latest advances in neural engineering and biomedical engineering as applied to the clinical diagnosis and treatment of Autism Spectrum Disorder (ASD). Advances in the role of neuroimaging, infrared spectroscopy, sMRI, fMRI, DTI, social behaviors and suitable data analytics useful for clinical diagnosis and research applications for Autism Spectrum Disorder are covered, including relevant case studies. The application of brain signal evaluation, EEG analytics, feature selection, and analysis of blood oxygen level-dependent (BOLD) signals are presented for detection and estimation of the degree of ASD.
    • Principles of Translational Science in Medicine

      • 3rd Edition
      • July 15, 2021
      • Martin Wehling
      • English
      • Hardback
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      Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields.
    • Advances in Probiotics

      • 1st Edition
      • July 15, 2021
      • Dharumadurai Dhanasekaran + 1 more
      • English
      • Paperback
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      Advances in Probiotics: Microorganisms in Food and Health highlights recent advances in probiotic microorganisms, commercial probiotics, safety aspects of probiotics, preparation and commercialization, microbiome therapy for diseases and disorders, and next generation probiotics. This is a comprehensive resource of developments of new formulations and products for probiotic and prebiotic food with focus on the microorganisms to enable effective probiotic delivery. The book deliberates contemporary trends and challenges, risks, limitations in probiotic and prebiotic food to deliver an understanding not only for research development purposes but also to benefit further standardize industrial requirements and other techno-functional traits of probiotics. At present there is no solitary volume to describe the probiotics and prebiotics properties, Advances in Probiotics: Microorganisms in Food and Health provides novel information to fill the overall gap in the market. It presents the most current information on probiotic and prebiotics for the food industry. This book is a valuable resource for academicians, researchers, food industrialists, and entrepreneurs.
    • Mitochondrial Dysfunction and Nanotherapeutics

      • 1st Edition
      • July 15, 2021
      • Marcos Roberto de Oliveira
      • English
      • Paperback
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      Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Relat... Strategies in Mitochondrial Medicine provides a comprehensive overview of mitochondrial dysfunction and current strategies for targeting the organelle. Based on the most current research, the editor lined up a team of worldwide experts to cover the most exciting research in the area, considering the impact through the human life span. This book is structured in two parts that provide a good balance of foundational and applied content. Part I deals with an overview of mitochondrial dysfunction and its role in the aging process, including metabolic diseases, neuro-affective and neurodegenerative disorders, sepsis, and toxicological aspects. Part II covers therapeutic substance delivery to mitochondria with a focus on cancer, neurodegenerative diseases, and increasing the bioavailability of natural compounds of interest. Several nanoscale strategies are described. Mitochondrial Dysfunction and Nanotherapeutics: Aging, Diseases, and Nanotechnology-Relat... Strategies in Mitochondrial Medicine is a complete resource for researchers in this exciting field. Its comprehensive coverage makes this book particularly interesting to bioscience researchers looking to understand the foundations of mitochondrial health throughout the human life span. Additionally, clinician researchers, medical doctors, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the organelle-targeted delivery strategies.
    • Mitochondrial Physiology and Vegetal Molecules

      • 1st Edition
      • July 14, 2021
      • Marcos Roberto de Oliveira
      • English
      • Paperback
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      Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health provides a comprehensive overview of mitochondrial physiology throughout the human life span, as well as the effect of molecules of vegetal origin on mitochondrial health. The editor has lined up a team of worldwide experts to cover the most exciting and high-impact advancements of research in this area. This book is structured into two parts that provide a balance of both foundational and applied content. Part I provides an overview of mitochondrial physiology including its structure, dynamics, biogenesis, membranes, DNA transcription, and translation in the mitochondria. Part I also covers other themes such as apoptosis. Part II then covers the effect of specific vegetable-derived molecules on mitochondrial health, including anthocyanins, caffeine, cannabinoids, carnosic and rosmarinic acids, citrus flavonoids, polyphenols, pterostilbene, resveratrol, and sulforaphane, among others. Mitochondrial Physiology and Vegetal Molecules: Therapeutic potential of natural compounds on mitochondrial health is a complete resource for researchers in this exciting field. Its comprehensive coverage makes it particularly interesting to bioscience researchers willing to understand the foundations of mitochondrial physiology throughout the human life span. Clinician researchers, MDs, nutritionists, pharmacologists, and sports scientists may be attracted to the detailed information on the health effects of vegetal origin molecules on the organelle.
    • Ocean Acidification and Marine Wildlife

      • 1st Edition
      • July 14, 2021
      • Guangxu Liu
      • English
      • Paperback
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      Ocean Acidification and Marine Wildlife: Physiological and Behavioral Impacts provides comprehensive knowledge on how decreases in the pH of the world’s oceans is affecting marine organisms. The book synthesizes recent findings about the impacts of ocean acidification (OA) on marine animals, covering the physiological and behavioral effects upon marine invertebrates and vertebrates, the potential physiological and molecular mechanism affects, and interactions of OA with other environmental factors. Written by international experts in this research field, this book summarizes new discoveries of OA effects on fertilization, embryonic development, biomineralization, metabolism, immune response, foraging, anti-predation, habitat selection, and the social hierarchy of marine animals. This is an important resource for researchers and practitioners in marine conservation, marine wildlife studies, and climate change studies. In addition, it will serve as a valuable text for marine biology and animal science students.
    • Microgrids and Methods of Analysis

      • 1st Edition
      • July 14, 2021
      • Gevork B. Gharehpetian + 2 more
      • English
      • Paperback
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      The increasing penetration of distributed energy resource (DER), distributed generation (DG) and energy storage system (ESS) units in distribution grids leads to the emergence of the concepts of active distribution networks (ADNs), microgrids, and virtual power plants. Nowadays, the use of electronically-coupl... distributed energy resources is of great interest that can provide the power of demand side alone or in a small electricity grid. A microgrid is a small-scale power grid in low voltage network that must be able to locally solve energy issues and enhance the flexibility and can operate either in grid-connected or islanded/autonomous mode of operation. To study them, researchers need an appropriate set of methods, software tools, analogous to those exist for large interconnected power systems.The book Microgrids and Methods of Analysis addresses systematic analysis, control/protection systems design, and optimal operation of a distribution system under high penetration of DERs analogous to those that exist for large interconnected power systems.
    • Epigenetics of Exercise and Sports

      • 1st Edition
      • Volume 25
      • July 13, 2021
      • Stuart M Raleigh
      • English
      • Paperback
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      Epigenetics of Exercise and Sports: Concepts, Methods, and Current Research explains fundamental epigenetic processes and how these are altered by exercise and sports. After a brief review of fundamental epigenetic biology, this all-new volume in the Translational Epigenetics series offers step-by-step instruction in how epigenetic factors are investigated for their influence over exercise related traits of human physiology, disease, and injury. The current state of knowledge in the field and recent findings are discussed in-depth, illuminating how exercise and sports performance may epigenetically modify our physiology, disease and injury risks, and how this knowledge can be applied in personalized exercise approaches, diagnostics, and treatment. This book also explores the shortcomings of explaining exercise related phenomena using only genomics and traditional biochemical techniques, setting the scene for a paradigm shift in exercise biology. In addition, over a dozen international specialists contribute chapters on exercise and sports epigenetics, and their influence over metabolism, obesity, aging, immunity, and neurological disease, as well as the epigenetic impacts of concussions and sports doping. A concluding chapter discusses ongoing themes in the field and outlooks for future research.