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    • Measuring Human Capital

      • 1st Edition
      • July 1, 2021
      • Barbara Fraumeni
      • English
      • Paperback
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      • eBook
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      Measuring Human Capital addresses a country’s most important resource: its own people. Bettering human capital benefits individuals and their country and leads to improved sustainability for the future. For many years economists only used Gross Domestic Product (GDP), now acknowledged to be inadequate without supplemental measures, to gauge a country’s overall value. There is now a recognition that many variables contribute to a country’s worth, which make accurate measurement difficult. Looking beyond GDP by focusing on human capital, researchers, policymakers, government officials, and students can understand what elements impact human capital and how they might improve it in order to increase economic growth and well-being.

    • Monitoring Vesicular Trafficking in Cellular Responses to Stress

      • 1st Edition
      • Volume 164
      • June 30, 2021
      • English
      • Hardback
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      • eBook
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      Monitoring Vesicular Trafficking in Cellular Responses to Stress, Volume 164 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

    • Molten Salt Reactors and Integrated Molten Salt Reactors

      • 1st Edition
      • June 29, 2021
      • Bahman Zohuri
      • English
      • Paperback
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      • eBook
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      Understanding the evolution and advances of energy conversion is critical to meet today’s energy demands while lowering emissions in the fight against climate change. One advancement within nuclear plants that continues to gain interest is molten salt reactors and integrated molten salt reactors, which are the new proposed generation IV small modular reactors. To get up to speed on the latest technology, Molten Salt Reactors and Integrated Molten Salt Reactors: Integrated Power Conversion delivers a critical reference covering the main steps for the application of these reactors. Creating a more environmentally friendly energy production methodology, the reference reviews the past, current, and future states of the reactors including pros and cons, designs and safety features involved, and additional references. Included in the reference is a new approach to energy conversion technology, including coverage on material, economic, and technical challenges towards waste heat recovery, power conversion systems, and advanced computational materials proposed for generation IV systems. Advanced nuclear open air-brayton cycles are also included for higher efficiency. Rounding out with guidance on avoiding salt freezing and salt cleanup for fission and fusion reactors, Molten Salt Reactors and Integrated Molten Salt Reactors: Integrated Power Conversion provides today’s nuclear engineer and power plant engineer with the impactful content of rising efficiency in molten salt reactors, ultimately leading to more efficient and affordable electricity.

    • Epigenetic Regulation in Overcoming Chemoresistance

      • 1st Edition
      • Volume 16
      • June 25, 2021
      • Chunfu Wu + 1 more
      • English
      • Hardback
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      • eBook
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      Epigenetic Regulation in Overcoming Chemoresistance, Volume 19, explains how epigenetic agents can enhance the chemotherapy sensitivity of diverse types of cancers. The book provides a comprehensive delineation and the recent development of the scientific studies on the epigenetic regulation in enhancing chemo-sensitivity. In addition, it discusses several topics such as DNA methyltransferase inhibitors (DNMTi), Histone deacetylases inhibitors (HDACi), Histone lysine demethylases inhibitors (HDMi), Histone lysine methyltransferases inhibitors (HMTi) and drugs regulating the microRNA, long non-coding RNA (lncRNA) or RNA methylation. Finally, recent and future developments of the field of epigenetic regulation are explored. This is a valuable resource for cancer researchers, clinicians, graduate students and several members of biomedical field who are interested in learning about epigenetic regulation methods to reverse chemo-resistance in cancers.

    • Advances in Immunology

      • 1st Edition
      • Volume 150
      • June 25, 2021
      • Frederick W. Alt
      • English
      • Hardback
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      • eBook
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      Advances in Immunology, Volume 150, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.

    • Prostate Cancer Metabolism

      • 1st Edition
      • June 25, 2021
      • Tomas Koltai + 3 more
      • English
      • Paperback
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      • eBook
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      • eBook
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      Prostate Cancer Metabolism: From Biochemistry to Therapeutics shows the peculiarities of prostate cancer metabolism, emphasizing the targetable aspects – that have not been considered in conventional treatment protocols. The book specifically addresses treatment of the castration-resistant stage of prostate cancer proposing many repurposed drugs and nutraceuticals to complement, not replace, standard therapies. The large body of evidence supporting these concepts makes them deserving of further research and well-designed clinical trials. It discusses lipid, cholesterol, glutamine, and glucose metabolisms and their impact on prostate cancer. Additionally, it explains how current established drugs can be repurposed to improve treatment outcomes. The concepts set out in the book, that deal with cancer at the cellular/molecular level, help identify new avenues of research and treatments to pursue that do not affect well-being whilst offer consistent benefits. Since most practicing physicians have not studied basic biochemistry since medical school, each chapter begins with a brief review of the topic to facilitate an understanding of the metabolically-orient... approach to targeting prostate cancer. Conventional treatments are not discussed here since they are covered in textbooks and specialized updates that abound in the medical literature. It is a valuable resource for cancer researchers, oncologists, clinicians and members of biomedical field who want to learn more about prostate cancer metabolism and how to apply recent findings in the field to bedside.

    • Advances in Atomic, Molecular, and Optical Physics

      • 1st Edition
      • Volume 70
      • June 25, 2021
      • Susanne Yelin + 2 more
      • English
      • Hardback
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      • eBook
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      Advances in Atomic, Molecular, and Optical Physics, Volume 70 provides a comprehensive compilation of recent developments in a field that is in a state of rapid growth as new experimental and theoretical techniques are used on many problems, both old and new. Topics covered include related applied areas, such as atmospheric science, astrophysics, surface physics, and laser physics, with timely articles written by distinguished experts.

    • Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies

      • 1st Edition
      • Volume 15
      • June 25, 2021
      • Ramasamy Paulmurugan + 1 more
      • English
      • Hardback
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      • eBook
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      Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood.

    • mRNA 3’ End Processing and Metabolism

      • 1st Edition
      • Volume 655
      • June 25, 2021
      • English
      • Hardback
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      • eBook
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      mRNA 3’ End Processing and Stability, Volume 655 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

    • Principles and Labs for Deep Learning

      • 1st Edition
      • June 25, 2021
      • Shih-Chia Huang + 1 more
      • English
      • Paperback
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      • eBook
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      Principles and Labs for Deep Learning provides the knowledge and techniques needed to help readers design and develop deep learning models. Deep Learning techniques are introduced through theory, comprehensively illustrated, explained through the TensorFlow source code examples, and analyzed through the visualization of results. The structured methods and labs provided by Dr. Huang and Dr. Le enable readers to become proficient in TensorFlow to build deep Convolutional Neural Networks (CNNs) through custom APIs, high-level Keras APIs, Keras Applications, and TensorFlow Hub. Each chapter has one corresponding Lab with step-by-step instruction to help the reader practice and accomplish a specific learning outcome. Deep Learning has been successfully applied in diverse fields such as computer vision, audio processing, robotics, natural language processing, bioinformatics and chemistry. Because of the huge scope of knowledge in Deep Learning, a lot of time is required to understand and deploy useful, working applications, hence the importance of this new resource. Both theory lessons and experiments are included in each chapter to introduce the techniques and provide source code examples to practice using them. All Labs for this book are placed on GitHub to facilitate the download. The book is written based on the assumption that the reader knows basic Python for programming and basic Machine Learning.

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