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Elsevier

Academic Press

  • MRI Atlas of the Infant Rat Brain

    Brain Segmentation
    • 1st Edition
    • Dusica Bajic + 2 more
    • English
    MRI Atlas of the Infant Rat Brain: Brain Segmentation features an entirely new coronal, sagittal and horizontal set of tissue cut in regular 9 µm intervals with accompanying photographs of MRI data and color drawings of selected brain regions in the three planes. The use of the single brain allows for greater consistency between sections, while color masking offers advances in manual segmentation techniques with increased refinement in the definition of brain areas. Readers will benefit from uniform and consistent manual tissue segmentation of MRI data in an infant rat brain. This volume provides readers the first infant rat brain MRI atlas and a valuable resource in research analyses of the developing brain for structural and functional MRI analyses.

  • Genetics and Neurobiology of Down Syndrome

    • 1st Edition
    • Bani Bandana Ganguly
    • English
    Genetics and Neurobiology of Down Syndrome provides a thorough review of the genetic etiology and mechanisms of trisomy 21. The author discusses the history of the syndrome, along with the clinical features and health consequences, including physical features, cognitive, and neurologic symptoms. Genetic counseling on pros and cons of prenatal screening and testing and associated ethical issues are explored. This unique book also covers the societal and demographic aspects as well as the future direction of therapeutic development.

  • System Vaccinology

    The History, the Translational Challenges and the Future
    • 1st Edition
    • Vijay Kumar Prajapati
    • English
    Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

  • Geophysical Exploration of the Solar System

    • 1st Edition
    • Volume 63
    • Cedric Schmelzbach + 1 more
    • English
    Advances in Geophysics serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Phytoconstituents and Antifungals

    • 1st Edition
    • Awanish Kumar
    • English
    Phytoconstituents and Antifungals covers a wide range of specific information on various phytoconstituents, their antifungal mode and the diagnosis and management of fungal infections. The book offers encouragement and empowers readers to re-embrace their knowledge of phytoconstituents and their various antifungal activities against most opportunistic pathogenic fungi as fungal diseases cause an estimated 1.5+ million deaths annually and over one billion people suffer from severe fungal disease. In this complex scenario, it is now clear that global warming and accompanying climate changes have resulted in increased incidence of many fungal infections. On the basis of all these factors, concerns on the occurrence of a pandemic fungal origin in the near future have been raised. In this context, to stop forgetting and underestimating fungal diseases is mandatory.

  • PDE Modeling of Tissue Engineering and Regenerative Medicine

    Computer Analysis in R
    • 1st Edition
    • William E. Schiesser
    • English
    PDE Modeling of Tissue Engineering and Regenerative Medicine: Computer Analysis in R presents the formulation and computer implementation of mathematical models for the forefront research areas of tissue engineering and regenerative medicine. The mathematical model discussed in this book consists of a system of eight partial differential equations (PDEs) with dependent variables. The computer-based example models are presented through routines coded in R—a quality, open-source scientific computing system that is readily available from the Internet. Formal mathematics is minimized, e.g., no theorems and proofs. Includes detailed examples that the reader can execute on modest computers.

  • Autophagy Dysfunction in Alzheimer's Disease and Dementia

    • 1st Edition
    • Tadanori Hamano + 1 more
    • English
    Autophagy Dysfunction in Alzheimer’s Disease and Dementia provides an overview for researchers and clinicians on the mechanisms involved in protein degradation in Alzheimer’s. The book discusses the implication of autophagy dysfunction in these diseases and how it causes degenerated proteins, including aggregated tau and aggregated amyloid protein. Other sections explores the possibilities of potential drug development through autophagy modulation, making this a great resource on the study of how autophagy dysfunction has been linked to the accumulation of misfolded proteins that cause death of neurons in Alzheimer’s and other neurodegenerative diseases.

  • Adversarial Robustness for Machine Learning

    • 1st Edition
    • Pin-Yu Chen + 1 more
    • English
    Adversarial Robustness for Machine Learning summarizes the recent progress on this topic and introduces popular algorithms on adversarial attack, defense and verification. Sections cover adversarial attack, verification and defense, mainly focusing on image classification applications which are the standard benchmark considered in the adversarial robustness community. Other sections discuss adversarial examples beyond image classification, other threat models beyond testing time attack, and applications on adversarial robustness. For researchers, this book provides a thorough literature review that summarizes latest progress in the area, which can be a good reference for conducting future research. In addition, the book can also be used as a textbook for graduate courses on adversarial robustness or trustworthy machine learning. While machine learning (ML) algorithms have achieved remarkable performance in many applications, recent studies have demonstrated their lack of robustness against adversarial disturbance. The lack of robustness brings security concerns in ML models for real applications such as self-driving cars, robotics controls and healthcare systems.

  • The Chromosome 22q11.2 Deletion Syndrome

    A Multidisciplinary Approach to Diagnosis and Treatment
    • 1st Edition
    • Donna M. McDonald-McGinn
    • English
    The Chromosome 22q11.2 Deletion Syndrome: A Multidisciplinary Approach to Diagnosis and Treatment serves as the first comprehensive, user-friendly resource on the etiology, prognosis, and recurrence risk associated with the chromosome 22q11.2 deletion syndrome. Leading international contributors cover the background, genetics, testing methods, and pathophysiology of 22q11.2DS, placing emphasis on a strong foundation for multidisciplinary treatment strategies. Written by specialists in every applicable subspecialty, such as, cardiology, immunology, endocrinology, gastroenterology, hematology, ophthalmology, neurology, and psychiatry, among other fields. This book presents an authoritative resource with full color images that enhance concept illustration and aid in real-time decision-making. As 22q11.2 deletion syndrome has become a model for understanding rare and frequent anomalies, numerous medical issues, cognitive and behavioral phenotypes, and later onset conditions, this text will become the go to resource for clinicians, researchers, trainees, and motivated family members, in gaining a full understanding of this complex chromosomal disorder.

  • Sex and Gender Differences in Neurological Disease

    • 1st Edition
    • Volume 164
    • English
    International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

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