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Elsevier

Academic Press

  • 3D Lung Models for Regenerating Lung Tissue

    • 1st Edition
    • Gunilla Westergren-Thorsson + 1 more
    • English
    3D Lung Models for Regenerating Lung Tissue is a comprehensive summary on the current state of art 3D lung models and novel techniques that can be used to regenerate lung tissue. Written by experts in the field, readers can expect to learn more about 3D lung models, novel techniques including bioprinting and advanced imaging techniques, as well as important knowledge about the complexity of the lung and its extracellular matrix composition. Structured into 15 different chapters, the book spans from the original 2D cell culture model on plastic, to advanced 3D lung models such as using human extracellular matrix protein. In addition, the last chapters cover new techniques including 3D printing, bioprinting, and artificial intelligence that can be used to drive the field forward and some future perspectives. This highly topical book with chapters on everything from the complexity of the lung and its microenvironment to cutting-edge 3D lung models, represents an exciting body of work that can be used by researchers during study design, grant writing, as teaching material, or to stay updated with the progression of the field.

  • Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies

    • 1st Edition
    • Manzoor Ahmad Mir
    • English
    Role of Tumor Microenvironment in Breast Cancer and Targeted Therapies discusses the current understanding of breast cancer tumor microenvironment components, their role in tumorigenicity and the development of therapeutic resistance, along with updates on recent advances.

  • Fish Roe

    Biochemistry, Products, and Safety
    • 1st Edition
    • Alaa El-Din A. (Aladin) Bekhit
    • English
    Provides comprehensive coverage of the components available in fish roe and highlights their biological and nutritional effects as well as their sensory and safety attributes. Fish Roe: Biochemistry, Products, and Safety describes various components available in fish roe and introduces their biological and nutritional effects. In addition to addressing biological and nutritional effects, this book also explores fish roe products and their safety while also providing coverage of the bioactives that are naturally available in fish roe or generated during processing, thereby outlining the maximum benefits that can be obtained from this natural resource. Beginning with the introduction of fish roe production procedures worldwide, this book further explores the processing of traditional fish roe products from Europe, Asia, and the Middle East, where fish roe is frequently consumed. This book also discusses the sensory and safety attributes of fish roe and will be a comprehensive reference for food scientists, chemists, food process engineers, developers, researchers, and students in the field of seafood science.

  • Application of Biofilms in Applied Microbiology

    • 1st Edition
    • Maulin P. Shah
    • English
    Application of Biofilms in Applied Microbiology gives a complete overview on the structure, physiology and application of biofilms produced by microbes, along with their potential application in biotechnology. Sections cover new technologies for biofilm study, physiology of microorganisms in biofilms, bacterial biofilms, biofilm development, and fungal biofilms, summarizing various technologies available for biofilm study. Subsequent chapters describe biofilm developments with Bacillus subtillis, Escherichia coli, and Pseudomonas putida, along with several chapters on the study of microbial biofilm and their advantages and disadvantages in the area of environmental biotechnology. The book closes with a chapter on the rapid development of new sequencing technologies and the use of metagenomics, thus revealing the great diversity of microbial life and enabling the emergence of a new perspective on population dynamics.

  • Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary

    • 1st Edition
    • Volume 95
    • English
    Pharmacology and Toxicology of Cytochrome P450 - 60th Anniversary, Volume 95 highlights the extensive contributions by worldwide researchers in the cytochrome P450 (P450) field over the past six decades, and since the first article on P450 was published in 1962. Chapters in this new release include Multiple conformations of cytochromes P450 and the relevance to predicting SAR, Pharmacogenetics of the cytochromes P450 and relevance to drug metabolism, Cytochromes P450 drug metabolism within the brain, Mammalian cytochrome P450 biodiversity: Physiological importance, function, and protein and genomic structures of cytochromes P4502B in multiple species of woodrats with different dietary preferences, and more. Additional section cover Atypical kinetics of cytochrome P450 enzymes in drug metabolism, Biosynthesis using cytochrome P450 Enzymes: focus on synthesis of drug metabolites, Use of engineered cytochrome P450s for accelerating drug discovery and development, Assessing cytochrome P450 function using genetically engineered mouse models, Use of the biologicals with sustainable reproducibility for phenotyping study of cytochrome P450 enzymes involved in the biotransformation of test compounds and calculating the fraction unbound parameter, for anticipating drug Interactions, and much more. Research on many forms of P450s has been extended into different fields, from molecules to in vivo situations because pharmacologists and toxicologists appreciate and are attracted to the potential therapeutics. The purpose of this volume is to collect a comprehensive description of major progress to date, to discuss possible future directions, and to invite young researchers to join this important and exciting world of P450.

  • Parathyroid Hormone

    • 1st Edition
    • Volume 120
    • English
    Vitamins and Hormones serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Methods in Stem Cell Biology - Part B

    • 1st Edition
    • Volume 171
    • English
    Methods in Cancer Stem Cell Biology: Part B, Volume 171 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Role of Chitosan and Chitosan-Based Nanomaterials in Plant Sciences

    • 1st Edition
    • Santosh Kumar + 1 more
    • English
    Role of Chitosan and Chitosan-Based Nanomaterials in Plant Sciences explores the physiological, morphological, biochemical and molecular regulation of chitosan and chitosan-based nanoparticles in plants in normal conditions, as well as during different stresses, and their probable mechanism of operation in the tolerance mechanism. The book stimulates further research in the field of chitosan and will foster further interests for researchers, academicians and scientists worldwide. Nanotechnology is being used widely in all disciplines of science and technology, including plant sciences. Chitosan has widely been reported as a beneficial organic compound for the growth and developments of plants and it plays a protective role for the plants against abiotic and biotic stresses. Yet there are very few books available that deal exclusively with Chitosan and Chitosan based nanoparticles impacts on plants respectively.

  • Autophagy and Metabolism

    Potential Target for Cancer Therapy
    • 1st Edition
    • Dhruv Kumar + 1 more
    • English
    Autophagy and Metabolism: Potential Target for Cancer Therapy presents updates on autophagy in cancer metabolism and how it can be used to develop new, more efficient treatments. Written by experts in the field, the book presents recent research and explains how to translate it to the clinical setting. Sections discuss tumor cell metabolism and autophagy as therapeutic targets, autophagy regulation in cancer, signaling pathways in metabolic dysregulation in solid tumors, metabolic stress and cell death pathways, and the role of the tumor microenvironment. In addition, topics cover combined targeting autophagy, metabolism for cancer therapy, and the autophagy effect on immune cell metabolism. This will be a valuable resource for researchers, oncologists, graduate students, and members of the biomedical field who are interested in learning more about the interaction between autophagy and cancer metabolism.

  • Targeted Nanomedicine for Breast Cancer Therapy

    • 1st Edition
    • Shivani Rai Paliwal + 1 more
    • English
    Targeted Nanomedicine for Breast Cancer Therapy provides a compilation of treatment approaches for breast cancer, including conventional receptor targeting methods and novel strategies like stimuli responsive methods and tumor micro-environment responsive strategies. This book compiles the most important information on the state-of-the-art therapeutics, including breast cancer biomarkers and design principles of bio-responsive nanosystems. Presented in two parts, sections cover basic and receptor mediated targeting approaches and examine tumor microenvironment mediated approaches. This is a useful book for pharmaceutical scientists and basic and clinical scientists working in the research area of breast cancer and drug discovery both from academics and industry.Worldwide, breast cancer is the most common cancer in women, however, breast cancer therapy is always challenging. This book aims to help researchers remain updated on the most targeted nanomedicine research available.

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