Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B

1st Edition, Volume 185 - November 15, 2021
Imprint: Academic Press
Editors: Rajesh S. Bhosale, Vijai Singh
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 6 0 4 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 9 6 0 5 - 1

Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help f… Read more

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Advances in Aggregation Induced Emission Materials in Biosensing and Imaging for Biomedical Applications - Part B, Volume 185 presents many aspects of AIE materials that can help future investigators, researchers, students and stakeholders perform research with ease. This volume covers various topics, including tissue and protein fibrils imaging by AIE active molecules, theranostic and photodynamic therapy applications of AIE materials for cancer cell treatment, and AIE active polymers and MOF materials for biological applications. Fluorescence-based monitoring and diagnosis platforms furnish extensive insights into the molecular mechanisms of cellular processes, helping us precisely guide therapeutics.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter One: Aggregation induced emission materials for tissue imaging
Abstract
1: Introduction
2: Mass spectrometric techniques for tissue imaging
3: Fluorescence spectroscopic techniques for tissue imaging
4: AIE molecular probes for deep tissue imaging
5: AIE nanoparticle probe for tissue imaging
6: AIE active conjugated polymer probe for tissue imaging
7: Conclusions and future prospect
Acknowledgments
References
Chapter Two: AIE materials for cancer cell detection, bioimaging and theranostics
Abstract
Graphical abstract
1: Introduction
2: AIE based materials in cancer cell detection
3: AIE based materials in bioimaging
4: AIE based materials in theranostics
5: AIE based materials for anticancer application
6: Conclusion, potential challenges, and future prospect
References
Chapter Three: AIE material for photodynamic therapy
Abstract
Graphical abstract
1: Introduction
2: Small molecule-based organelle targeting AIEgens for PDT
3: Small-molecule based AIEgens for two-photon PDT
4: Metal complexes as AIEgens for PDT
5: Targeted peptide conjugated AIEgens for PDT
6: Combination of chemotherapeutic agent functionalized AIE-PS for chemo-photodynamic therapy
7: Polymer based AIE-PS for PDT
8: Nanoparticles (NPs) based AIE-PS for PDT
9: AIE-PS nanoparticles for combination PDT
10: Concluding remarks and future directions
Acknowledgments
References
Chapter Four: Aggregation induced bright organic luminogens: Design strategies, advanced bio-imaging and theranostic applications
Abstract
Graphical abstract
1: Introduction
2: Basic aspects and design strategy
3: Theranostic application
4: Fluorescence-based imaging with NIR-AIEgens
5: AIE-RTP-active molecules for bio-imaging
6: AIE-TADF emitter for biomedical applications
7: Conclusion and outlook
References
Chapter Five: Aggregation-induced emission materials for protein fibrils imaging
Abstract
1: Introduction
2: Protein fibrillation
3: Protein fibrils imaging
4: AIE probes for amyloid detection
5: Perspectives
References
Chapter Six: AIE active polymers for biological applications
Abstract
1: Introduction
2: Diagnostics with AIE active polymer
3: Imaging with AIE active polymer
4: Biomedical application of AIE active polymer
5: Conclusion and outlook
References
Chapter Seven: AIE-MOF materials for biological applications
Abstract
1: Metal organic frameworks
2: Aggregation-induced emission of MOFs
3: AIE of MOF materials for biological applications
4: Summary and perspectives
References
Chapter Eight: Patented AIE materials for biomedical applications
Abstract
1: Introduction
2: Biomedical applications
3: Future prospectus
Acknowledgments
References
Index

Rajesh S. Bhosale

Dr. Rajesh S. Bhosale is an Associate Professor at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He did his PhD (2009) from University of Geneva (Switzerland) under the supervision of Prof. Stefan Matile. Thereafter, he did first post-doctoral research as SNSF postdoctoral fellow from top institutes of World i.e. MIT-Massachusetts Institute of Technology, Cambridge, USA in the group of Prof. Timothy M. Swager and second post-doctoral research as DFG postdoctoral fellow from FRIAS-Freiburg Institute for Advanced Studies, Germany in the group of Prof. Aurelio Mateo-alonso. Where he was excelled in challenging multistep chemical synthesis, electrochemical, photophysical and self-assembly properties study of small molecules, macromolecules and polymer chromophoric systems. He also served as RMIT research associate in the group of Prof. M. Lakshmi Kantam at CSIR-IICT, Hyderabad and in July 2015 he becomes a CSIR scientist pool officer. His research interests are focused on building AIE active novel molecules.

Affiliations and expertise

Associate Professor, Department of Chemistry, School of Science, Indrashil University, Rajpur, Mehsana, Gujarat, India

Vijai Singh

Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.

Affiliations and expertise

Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, India

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health