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    • Personalized Health Systems for Cardiovascular Disease

      • 1st Edition
      • January 21, 2022
      • Anna Maria Bianchi + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 9 5 0 4
      • eBook
        9 7 8 0 1 2 8 1 9 0 6 6 1
      Personalized Health Systems for Cardiovascular Disease is intended for researchers, developers, and designers in the field of p-health, with a specific focus on management of cardiovascular diseases. Biomedical engineers will benefit from coverage of sensors, data transmission, signal processing, data analysis, home and mobile applications, standards, and all other subject matters developed in this book in order to provide an integrated view of the different and multidisciplinary problems related to p-health systems. However, many chapters will also be interesting to physicians and other professionals who operate in the health domain. Students, MS and PhD level, mainly in technical universities, but also in medical schools, will find in this book a complete view of the manifold aspects of p-health, including technical problems related to sensors and software, to automatic evaluation and correct interpretation of the data, and also some legal and regulatory aspects. This book mainly focuses on the development of technology used by people and patients in the management of their own health. New wearable and implantable devices allow a continuous monitoring of chronic patients, with a direct involvement of clinical centers and physicians. Also, healthy people are more and more interested in keeping their own wellness under control, by adopting healthy lifestyles and identifying any early sign of risk. This is leading to personalized solutions via systems which are tailored to a specific patient/person and her/ his needs. However, many problems are still open when it comes to p-health systems. Which sensors and parameters should be used? Which software and analysis? When and how? How do you design an effective management plan for chronic pathologies such as cardiovascular diseases? What is useful feedback for the patient or for the clinician? And finally, what are the limits of this approach? What is the view of physicians? The purpose of this book is to provide, from a technical point of view, a complete description of most of the elements which are part of such systems, including the sensors and the hardware, the signal processing and data management procedures, the classification and stratification models, the standards and the regulations, focusing on the state of the art and identifying the new directions for innovative solutions. In this book, readers will find the fundamental elements that must be taken into account when developing devices and systems in the field of p-health.

    • Debulking in Cardiovascular Interventions and Revascularization Strategies

      • 1st Edition
      • January 21, 2022
      • On Topaz
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 4 5 1 0
      • eBook
        9 7 8 0 1 2 8 2 1 4 6 2 6
      Debulking in Cardiovascular Interventions and Revascularization Strategies: Between a Rock and the Heart aims to provide a comprehensive overview on the diagnostic and therapeutic aspects of resistant lesions as well as tailored debulking processes in revascularization strategies. Cardiovascular interventionalists and surgeons alike frequently encounter technical challenges and increased risk when attempting to diagnose and treat resistant cardiovascular lesions, bio-tissues and vessels. Calcified plaques, fibrotic or thrombotic lesions, total occlusions, degenerative plaques, complex lesions and vessels impose morphologic obstacles to the safe and effective delivery and deployment of balloons and stents. In such instances, a debulking strategy involving the actual drilling and extraction of the targeted plaque/bio-tissue constitutes a unique option that ensures safe and efficacious subsequent balloon dilatations and stenting.A range of topics is included in the book, from the characteristics and constituents of various resistant targets and bio-tissues, to the corresponding options of debulking methods, and finally the technologic and pharmacologic means available for application.The book also provides an up-to-date description of related management solutions and tools, exploring the medical issues pertaining to the patients with these targets; procedural results and clinical outcomes as related to debulking strategies and associated diagnostic and therapeutic technology and revascularization options.

    • Gene Regulatory Mechanisms in Development and Evolution: Insights from Echinoderms

      • 1st Edition
      • Volume 146
      • January 20, 2022
      • English
      • Hardback
        9 7 8 0 1 2 8 1 7 1 8 7 5
      • eBook
        9 7 8 0 1 2 8 1 7 1 8 8 2
      Sea urchins and other echinoderms, which have been studied intensively by developmental biologists for more than a century, are currently among the most prominent models for elucidating the genomic regulatory processes that control embryogenesis and the evolution of those processes. This volume contains reviews from the world’s leading researchers who are using echinoderms to address these questions. Chapters focus on gene regulatory networks that drive the differentiation and morphogenesis of major embryonic tissues such as the skeleton, muscle, nervous system, immune system, pigment cells, and germ line, and on evolutionary insights from comparative studies of these networks across echinoderms and other taxa. Other chapters comprehensively review the architecture and evolution of the cell signaling pathways that establish the early embryonic axes and on recent evolutionary changes in gene networks that have led to dramatic changes in the life history modes of echinoderms. This volume provides a comprehensive, current picture of exciting research at the interface between developmental genomics and evolution from one of the research communities leading this work.

    • Encyclopedia of Violence, Peace, and Conflict

      • 3rd Edition
      • January 20, 2022
      • Lester R. Kurtz
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 1 9 5 4
      • eBook
        9 7 8 0 1 2 8 2 0 3 1 2 5
      Encyclopedia of Violence, Peace and Conflict, Third Edition, Four Volume Set provides timely and useful information about antagonism and reconciliation in all contexts of public and personal life, from the interpersonal to the global. Building on the highly-regarded 1st and 2nd editions (1999, 2008), and publishing at a time of increasing conflict and violent behavior the world over, this book is an essential reference for students and scholars working in the social scientific study of peace and conflict, criminology, public policy and international relations, as well as for those seeking to explore alternatives to violence and share visions and strategies for social justice and change. Covering topics as diverse as Sexual Assault, Terrorism, Arms Control, Nonviolent Movements, Child Abuse, Folklore, and Political Assassinations, the Encyclopedia comprehensively addresses an extensive information area in over 250 transdisciplinary, cross-referenced and authoritatively authored articles.

    • Mechanics and Physics of Structured Media

      • 1st Edition
      • January 20, 2022
      • Igor Andrianov + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 5 4 3 5
      • eBook
        9 7 8 0 3 2 3 9 0 6 5 3 1
      Mechanics and Physics of Structured Media: Asymptotic and Integral Methods of Leonid Filshtinsky provides unique information on the macroscopic properties of various composite materials and the mathematical techniques key to understanding their physical behaviors. The book is centered around the arguably monumental work of Leonid Filshtinsky. His last works provide insight on fracture in electromagnetic-elas... systems alongside approaches for solving problems in mechanics of solid materials. Asymptotic methods, the method of complex potentials, wave mechanics, viscosity of suspensions, conductivity, vibration and buckling of functionally graded plates, and critical phenomena in various random systems are all covered at length. Other sections cover boundary value problems in fracture mechanics, two-phase model methods for heterogeneous nanomaterials, and the propagation of acoustic, electromagnetic, and elastic waves in a one-dimensional periodic two-component material.

    • Fundamentals of Wind Farm Aerodynamic Layout Design

      • 1st Edition
      • January 20, 2022
      • Farschad Torabi
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 0 1 6 9
      • eBook
        9 7 8 0 1 2 8 2 3 4 3 7 2
      Fundamentals of Wind Farm Aerodynamic Layout Design, Volume Four provides readers with effective wind farm design and layout guidance through algorithm optimization, going beyond other references and general approaches in literature. Focusing on interactions of wake models, designers can combine numerical schemes presented in this book which also considers wake models’ effects and problems on layout optimization in order to simulate and enhance wind farm designs. Covering the aerodynamic modeling and simulation of wind farms, the book's authors include experimental tests supporting modeling simulations and tutorials on the simulation of wind turbines. In addition, the book includes a CFD technique designed to be more computationally efficient than currently available techniques, making this book ideal for industrial engineers in the wind industry who need to produce an accurate simulation within limited timeframes.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 106
      • January 20, 2022
      • Gregory S. Makowski
      • English
      • Hardback
        9 7 8 0 3 2 3 9 8 8 3 7 7
      • eBook
        9 7 8 0 3 2 3 9 8 8 3 8 4
      Advances in Clinical Chemistry, Volume 106, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, with this new release focusing on Advances in ADAMTS biomarkers, Advances in fibrosis biomarkers in nonalcoholic fatty liver disease, Metabolomics of Peripheral Artery Disease, Molecular and cellular functions of long non-coding RNAS in prostate and breast cancer, Myostatin: Basic Biology to Clinical Application, and Metadherin (AEG-1/MTDH/LYRIC) expression: Significance in malignancy and crucial role in colorectal cancer.

    • Clinical Applications of Noncoding RNAs in Cancer

      • 1st Edition
      • January 19, 2022
      • Subash Gupta + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 5 5 0 7
      • eBook
        9 7 8 0 1 2 8 2 4 5 5 1 4
      Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject. This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed. It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types.

    • The Pharmacological Potential of Cyanobacteria

      • 1st Edition
      • January 19, 2022
      • Graciliana Lopes + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 4 9 1 6
      • eBook
        9 7 8 0 1 2 8 2 1 4 9 2 3
      The Pharmacological Potential of Cyanobacteria explores the bioactive compounds isolated from cyanobacteria and their relationship to human health and biotechnological applications. The book presents an overview of the chemistry and ecology of cyanobacteria, focusing on culture needs and techniques of biomass production. It is organized according to the different biological activities and biotechnological applications of compounds discovered in recent years. Besides biological activity, the mechanism of action of compounds is explained, along with molecular structure. Finally, compounds already used in therapeutics and biotechnology, as well as those in phases of approval or clinical trials are explored. Each chapter is written by a different research group with expertise in the field and publications in peer reviewed journals. Researchers and students in pharmaceutical academic research, pharmaceutical industrial sector personnel, health professionals, and nutritionists will find this book to be very useful.

    • Diabetes Without Needles

      • 1st Edition
      • January 19, 2022
      • Artur Rydosz
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 8 8 7 1
      • eBook
        9 7 8 0 3 2 3 9 8 5 2 9 1
      Diabetes Without Needles: Non-invasive Diagnostics and Health Management provides a comprehensive and objective compilation of the most promising noninvasive methods for glucose monitoring, including an in-depth analysis of their advantages and disadvantages in terms of biochemical processes. The latest advances in the field are discussed, including methods such as optical measurements, electrochemical measurements, exhaled breath analysis, direct measurements of glucose in the blood using noninvasive techniques, and the indirect analysis of biomarkers that are related to the glycemia. The book's author also presents recommendations for future research directions in this field. This book is a valuable resource for researchers in the areas of diabetes, noninvasive methods and diagnostics development.

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