
Clinical Applications of Noncoding RNAs in Cancer
- 1st Edition - January 19, 2022
- Imprint: Academic Press
- Editors: Subash Gupta, Kishore Challagundla
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 5 0 - 7
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 4 5 5 1 - 4
Clinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Establish… Read more

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Request a sales quoteClinical Applications of Noncoding RNAs in Cancer summarizes the existing strategies, advances, and future opportunities on the role of noncoding RNAs in cancer patients. Established clinicians and researchers from all around the world share their views and expertise and provide readers with invaluable knowledge on the subject.
This book provides a comprehensive collection of information on the utility of noncoding RNAs in the diagnosis, prognosis, and therapy of cancer. It also discusses the evolutionary significance of noncoding RNAs and how the molecular tools such as RNA-seq, RNA-FISH, ic-SHAPE, and quantitative real-time PCR help in the detection and elucidation of the functions of noncoding RNAs. Additionally, the challenges associated with noncoding RNA approaches and future developments are discussed.
It is a valuable resource for cancer researchers, oncologists, clinicians, and other biomedical field members who want to learn more about noninvasive ways to diagnose and efficiently treat diverse cancer types.
- Presents a beginning chapter summary to help readers understand the content thoroughly
- Encompasses detailed description of information from clinical studies on noncoding RNAs in cancer therapy
- Discusses one cancer type per chapter making the content easy to reference
Cancer researchers, oncologists, clinicians, medical scientists
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Chapter 1. Noncoding ribonucleic acid for pancreatic cancer therapy
- Abstract
- 1.1 Introduction
- 1.2 Experimental methods and tools for analyzing noncoding RNAs in pancreatic cancer patients
- 1.3 Bioinformatics for analyzing noncoding RNAs in pancreatic cancer patients
- 1.4 Noncoding RNA
- 1.5 Pancreatic cancer–specific microRNAs
- 1.6 Pancreatic cancer–associated lncRNAs
- 1.7 Pancreatic cancer–associated circular RNAs
- 1.8 Diagnostic microRNA markers of PDAC
- 1.9 Diagnostic lncRNA markers of PDAC
- 1.10 Diagnostic circular RNA markers of PDAC
- 1.11 Summary and conclusion
- Acknowledgment
- References
- Chapter 2. Applications of noncoding RNAs in brain cancer patients
- Abstract
- 2.1 Introduction
- 2.2 Data sets for noncoding RNAs analysis
- 2.3 Expression of noncoding RNAs in brain cancer patients
- 2.4 Experimental methods and tools for analyzing noncoding RNAs in brain cancer patients
- 2.5 Noncoding RNAs as predictive marker for brain cancer patients
- 2.6 Potential of noncoding RNAs in predicting chemoresistance and radioresistance in brain cancer patients
- 2.7 Therapeutic potential and targeting of ncRNAs in brain cancer patients—challenges and perspectives
- 2.8 Summary and conclusions
- References
- Chapter 3. Noncoding RNAs in patients with colorectal cancer
- Abstract
- 3.1 Introduction
- 3.2 Experimental methods and tools for analyzing noncoding RNAs in colorectal cancer patients
- 3.3 Microarray
- 3.4 Serial analysis of gene expression
- 3.5 Cap analysis gene expression
- 3.6 RNA sequencing
- 3.7 Dataset and bioinformatics for analyzing noncoding RNAs in colorectal cancer patients
- 3.8 Expression of noncoding RNAs in colorectal cancer patients
- 3.9 Sample types used for analyzing noncoding RNAs
- 3.10 Cell signaling pathways modulated by noncoding RNAs in colorectal cancer patients
- 3.11 Several other mechanisms
- 3.12 Clinical applications of noncoding RNAs as biomarkers in patients with colorectal cancer
- 3.13 Diagnostic potential of noncoding RNAs in colorectal cancer patients
- 3.14 Prognostic potential of noncoding RNAs in colorectal cancer patients
- 3.15 Therapeutic potential of noncoding RNAs in colorectal cancer patients
- 3.16 Potential of noncoding RNAs in predicting chemoresistance and radioresistance in colorectal cancer patients
- 3.17 Conclusion
- References
- Chapter 4. Applications of noncoding ribonucleic acids in multiple myeloma patients
- Abstract
- 4.1 Introduction
- 4.2 Samples and experimental methods for the analysis of noncoding RNAs in multiple myeloma patients
- 4.3 Datasets analyzing noncoding RNAs in multiple myeloma patients
- 4.4 Noncoding RNAs implicated in the etiology of multiple myeloma
- 4.5 Cell signaling pathways modulated by noncoding RNAs in multiple myeloma
- 4.6 Noncoding RNAs affecting interactions with the bone marrow niche
- 4.7 Noncoding RNAs as diagnostic and prognostic biomarkers in multiple myeloma
- 4.8 Therapeutic potential of noncoding RNAs in multiple myeloma patients
- 4.9 Summary and conclusion
- Acknowledgments
- References
- Chapter 5. Clinical applications of noncoding RNAs in lung cancer patients
- Abstract
- Abbreviations
- 5.1 Introduction
- 5.2 Experimental methods and tools for analyzing ncRNAs in lung cancer patients
- 5.3 Datasets and informatics for analyzing ncRNAs in lung cancer patients
- 5.4 Expression of ncRNAs in lung cancer patients
- 5.5 Sample types used for analyzing ncRNAs
- 5.6 Cell signaling pathways modulated by ncRNAs in lung cancer patients
- 5.7 NcRNAs as predictive markers for lung cancer patients
- 5.8 Diagnostic potential of ncRNAs in lung cancer patients
- 5.9 Prognostic potential of ncRNAs in lung cancer patients
- 5.10 Therapeutic potential of ncRNAs in lung cancer patients
- 5.11 Potential of ncRNAs in predicting chemoresistance and radioresistance in lung cancer patients
- 5.12 Summary and conclusion
- Acknowledgments
- References
- Chapter 6. Noncoding RNAs in intraocular tumor patients
- Abstract
- 6.1 Introduction
- 6.2 Retinoblastoma
- 6.3 Uveal melanoma
- 6.4 Conclusion
- References
- Chapter 7. Applications of noncoding RNAs in renal cancer patients
- Abstract
- 7.1 Introduction
- 7.2 Datasets and informatics for analyzing noncoding RNAs in renal cancer patients
- 7.3 Expression of noncoding RNAs in renal cancer patients
- 7.4 Cell signaling pathways modulated by noncoding RNAs in renal cancer patients
- 7.5 Diagnostic potential of noncoding RNAs in renal cancer patients
- 7.6 Prognostic potential of noncoding RNAs in renal cancer patients
- 7.7 Therapeutic potential of noncoding RNAs in renal cancer patients
- 7.8 Potential of noncoding RNAs in predicting chemoresistance and radioresistance in renal cancer patients
- 7.9 Summary and conclusion
- References
- Chapter 8. Clinical significance of long noncoding RNAs in breast cancer patients
- Abstract
- Abbreviations
- 8.1 Introduction
- 8.2 Potential of lncRNAs in the diagnosis of breast cancer
- 8.3 Potential of lncRNAs in the prognosis of breast cancer
- 8.4 Potential of lncRNAs in breast cancer therapy
- 8.5 Potential of lncRNAs in predicting breast cancer patient’s response to therapeutics
- 8.6 Potential of lncRNAs in predicting chemoresistance and radioresistance in breast cancer patients
- 8.7 Experimental methods and tools for analyzing noncoding RNAs in cancer patients
- 8.8 Summary and conclusion
- Acknowledgment
- References
- Chapter 9. Noncoding ribonucleic acids in gastric cancer patients
- Abstract
- 9.1 Introduction
- 9.2 Experimental methods and tools for analyzing noncoding RNAs in gastric cancer patients
- 9.3 Expression of noncoding RNAs in gastric cancer patients
- 9.4 Sample types used for analyzing noncoding RNAs (tumor biopsies, liquid biopsies, etc.)
- 9.5 Cell signaling pathways modulated by noncoding RNAs in gastric cancer patients
- 9.6 Noncoding RNAs as prognostic and predictive marker for gastric cancer patients
- 9.7 Diagnostic value of small noncoding RNAs in gastric cancer
- 9.8 Potential of noncoding RNAs in predicting chemotherapy resistance and radiotherapy resistance in gastric cancer patients
- 9.9 Summary and conclusion
- References
- Chapter 10. Noncoding RNAs in prostate cancer patients
- Abstract
- 10.1 Introduction
- 10.2 Experimental methods and tools for analyzing ncRNAs in prostate cancer patients
- 10.3 Datasets and informatics for analyzing noncoding RNAs
- 10.4 Sample types used for analyzing ncRNAs (tumor biopsies, liquid biopsies, etc.)
- 10.5 Cell signaling pathways modulated by ncRNAs in prostate cancer
- 10.6 NcRNAs as biomarkers for prostate cancer
- 10.7 Therapeutic potential of ncRNAs in prostate cancer patients
- 10.8 Potential of ncRNAs in predicting chemo-resistance and radioresistance in prostate cancer patients
- 10.9 Conclusion
- References
- Chapter 11. Noncoding RNAs in liver cancer patients
- Abstract
- Abbreviations
- 11.1 Introduction
- 11.2 NcRNA roles in liver development and functions
- 11.3 Noncoding RNA detection
- 11.4 Expression of ncRNAs in liver cancers
- 11.5 Noncoding RNA relevance in liver cancer diagnosis and prognosis
- 11.6 Summary and conclusion
- Acknowledgments
- References
- Chapter 12. Noncoding ribonucleic acids in gallbladder cancer patients
- Abstract
- 12.1 Introduction
- 12.2 MiRNAs in gallbladder carcinoma
- 12.3 LncRNAs in gallbladder carcinoma
- 12.4 PiRNAs in gallbladder carcinoma
- 12.5 Limitations of clinical utility of ncRNAs in gallbladder carcinoma
- 12.6 Conclusion
- References
- Chapter 13. Clinical implications of noncoding RNAs in neuroblastoma patients
- Abstract
- 13.1 Introduction
- 13.2 Types of noncoding RNAs
- 13.3 Role of noncoding RNAs in neuroblastoma growth and development
- 13.4 Clinical significance of noncoding RNAs in neuroblastoma
- 13.5 Therapeutic implications and targeting strategies for noncoding RNAs in neuroblastoma
- 13.6 Conclusion
- Acknowledgments
- Conflict of interest
- References
- Chapter 14. Potential clinical application of lncRNAs in pediatric cancer
- Abstract
- 14.1 Introduction
- 14.2 Experimental and bioinformatics tools for studying lncRNAs
- 14.3 LncRNAs in pediatric cancer
- 14.4 Conclusion and perspectives
- Acknowledgment
- References
- Index
- Edition: 1
- Published: January 19, 2022
- No. of pages (Paperback): 478
- No. of pages (eBook): 478
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780128245507
- eBook ISBN: 9780128245514
SG
Subash Gupta
KC