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Elsevier

Academic Press

  • Alzheimer's Disease and Advanced Drug Delivery Strategies

    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    Alzheimer's Disease and Advanced Drug Delivery Strategies compiles under a single volume the most recent advances in drug delivery to the brain as related to AD treatment. The book's editors recruited scientists from around the world to produce high quality chapters covering not only nanotechnological approaches, but also microsphere, niosomes, and liposomes. Among the topics covered are synthetic molecules, nobiletin, nose to brain delivery, natural biomaterials, cationic nanoformulations, dendrimers, microbubbles, and more. This book represents a complete reference for academic and corporate pharma researchers investigating targeted drug delivery to the brain.

  • Next Generation Sequencing (NGS) Technology in DNA Analysis

    • 1st Edition
    • Hirak Ranjan Dash + 2 more
    • English
    Next Generation Sequencing (NGS) Technology in DNA Analysis explains and summarizes next generation sequencing (NGS) technological applications in the field of forensic DNA analysis. The book covers the transition from capillary electrophoresis (CE)-based technique to NGS platforms and the fundamentals of NGS technologies, applications, and advances. Sections provide an overview of NGS technology and forensic science, including information on processing biological samples for forensic analysis, sequence analysis, and data analysis software as well as the analysis of NGS data. The book explores the valuable applications of NGS-based forensic DNA analysis and covers the validations and interpretation guidelines of NGS workflows. With chapter contributions from an international array of experts and the inclusion of practical case studies, this book is a useful reference for academicians and researchers in genetics, biotechnology, bioinformatics, biology, and medicine as well as forensic DNA scientists and practitioners who aim to learn, use, apply, and validate NGS-based technologies.

  • Translational Glycobiology in Human Health and Disease

    • 1st Edition
    • Michelle Kilcoyne + 1 more
    • English
    Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translatio... Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery.

  • Silver Nanoparticles for Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Silver Nanoparticles for Drug Delivery is a complete reference that provides comprehensive coverage of the principle behind the formation, characterization, application, regulation, toxicity, and challenges and future perspectives of silver nanoparticles in drug delivery for the treatment of various diseases. Sections cover the synthesis and characterization of silver nanoparticles (AgNPs), historical introductions to developments, methods and characterization parameters, green and biological synthesis methods, biofate and cellular interactions of AgNPs, drug delivery for the treatment of several diseases and conditions, targeting strategies, applications in cancer diagnosis and treatment, and much more. This is a complete reference for graduate students in nanotechnology drug delivery.

  • Gold Nanoparticles for Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Gold Nanoparticles for Drug Delivery discusses the synthesis and characterization of gold nanoparticles (AuNPs), presenting an historical introduction to the developments in the area, discussing methods and characterization parameters, covering targeted delivery strategies, treatment of cancer, CNS conditions, infectious diseases, HIV/AIDS infection, wound healing and tissue regeneration, dentistry, gene delivery, and its photo properties used in diagnostic and therapies, and finally presenting regulatory aspects such as theranostic applications, vaccine development, toxicity, and the translation of research to marketable products. This book is a complete reference for researchers in nanotechnology drug delivery and pharmaceutical disciplines. Researchers in pharmaceutical industries, especially those involved in the use of gold nanoparticles in the field of drug delivery, diagnosis, targeted and early therapies will also benefit from this book.

  • Steroid Hormone Receptors in Health and Disease

    • 1st Edition
    • Raj Kumar + 1 more
    • English
    Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases.

  • Wireless Power Transfer for E-Mobility

    Fundamentals and Design Guidelines for Wireless Charging of Electric Vehicles
    • 1st Edition
    • Mauro Feliziani + 3 more
    • English
    Wireless Power Transfer for e-Mobility: Fundamentals and Design Guidelines for Wireless Charging of Electric Vehicles provides a comprehensive resource for researchers and engineers engaged in the development of automotive WPT systems. The book opens with an overview of wireless technologies for power transfer and their evolution over time, then focusing on the application of this technology to electric mobility highlighting its importance in terms of impact and perspectives on the development of sustainable transport and autonomous driving. Chapters discuss the fundamentals of electromagnetic field in WPT systems and the circuit modelling. In addition, they examine core current electric vehicle systems and present-day automotive WPT standards. Design techniques of magnetic couplers, including compensation networks are explored in-depth alongside power electronics techniques for automotive WPT systems. Both stationary and dynamic automotive WPT systems are rigorously assessed. Finally, the problems of electromagnetic compatibility and electromagnetic field safety are described with particular attention to shielding techniques for the mitigation of magnetic field emissions. Addressing essential knowledge from foundational to advanced levels, Wireless Power Transfer for e-Mobility provides practical guidance to engineers and researchers developing the future of electric mobility.

  • Insects as Food and Food Ingredients

    Technological Improvements, Sustainability, and Safety Aspects
    • 1st Edition
    • Marco Garcia-Vaquero + 1 more
    • English
    Insects as Food and Food Ingredients: Technological Improvements, Sustainability, and Safety Aspects addresses the use of insects as food by following a farm-to-fork approach and covering general aspects concerning farming, processing and the main applications of insects and insect derived ingredients in the food sector. Broken into three sections, this book addresses insect farming, the challenges of processing whole insects, or their fractionation into insect ingredients by the means of conventional and innovative technologies, as well as the biological properties, application, safety, functionality and nutritional value of both insects and their ingredients for food applications. Nutrition researchers, nutritionists, food scientists, health professionals, agricultural researchers, biosystem engineers and those working in or studying related disciplines will benefit from this reference.

  • Stem Cells

    An Alternative Therapy for COVID-19 and Cytokine Storm
    • 1st Edition
    • Yogesh Kumar Verma + 4 more
    • English
    Stem Cells: An Alternative Therapy for COVID-19 and Cytokine Storm provides mechanistic insights into the role of stem cells to combat COVID-19 outbreak and other pathologies where cytokines storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. There has been an increase in number of cases of new diseases in the last decade, including mucormycosis, Zika virus, H1N1 influenza virus, among others. These diseases can be characterized by the induction of cytokine storm, which is mainly responsible for morbidity and mortality.Stem cell therapy has emerged as a potential treatment for viral diseases, including, but not limited to, COVID-19. Interestingly, clinical trials in patients with COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue.

  • The Brain of the Critically Ill Pregnant Woman

    • 1st Edition
    • Javier Perez-Fernandez + 2 more
    • English
    The Brain of the Critically Ill Pregnant Woman is a volume in the Critical Care in Obstetrics series. This novel reference educates physicians, nurses, and all allied healthcare personnel on updates for caring for pregnant women with neurological compromise. The book's authors have gathered the best evidence-based material that is explicitly focused on severe neurological complications in pregnant patients and postpartum. Among the chapters, the book covers medical-surgical complications that any patient can present, such as head trauma and complications specific to pregnancy.

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