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Academic Press

  • Raising Genomics Literacy, Knowledge, and Awareness

    • 1st Edition
    • Azhar T. Rahma + 1 more
    • English
    Raising Genomics Literacy, Knowledge, and Awareness is a unique resource which describes the importance of genomic literacy for the effective and streamlined implementation of genomic medicine and pharmacogenomics globally. It provides evidence and expert opinion to decipher the role of genomic and pharmacogenomic literacy to illustrate the evidence, value, and need of raising genomics awareness and education among healthcare professionals, students, and the general public. This text can be used by researchers and graduate students pursuing research in this area.

  • The Living Laboratory for Precision Medicine

    Solutions for Clinical Implementation
    • 1st Edition
    • Dame Anna Dominiczak + 2 more
    • English
    The Living Laboratory for Precision Medicine: Solutions for Clinical Implementation provides a comprehensive resource on precision medicine through a convergence of innovation and solutions across multiple domains, including large population cohorts, artificial intelligence, genomics, phenomics, clinical trials, health economics and regulation exemplified by the living lab concept. This book is the first to look at precision medicine through the lens of last-mile solutions which make it broad in scope, practically relevant, and cutting-edge. The book explores the use of precision medicine to stimulate regional economic growth through a healthier population, savings on healthcare, and using innovation as a driver of economic development. The term precision medicine has been popularized by clinical, scientific, political, financial and technological interests as the biggest innovation to revolutionize healthcare. While over the past decade a few precision medicine-based solutions have come to fruition, the transformative leap in healthcare delivery and population benefit is yet to be realized. Current focus on precision medicine primarily focuses on patient stratification which constrains it to either a single disease area, a few sub-disciplines, or using a limited set of genomic technologies. While useful, experience over the last few years indicates precision medicine needs to be considered as a complex process with multiple feedback loops requiring significant interdisciplinary collaboration and innovation.

  • Diabetes Mellitus

    Target Enzymes and Drugs
    • 1st Edition
    • Manisha Nidhar + 1 more
    • English
    Diabetes Mellitus: Target Enzymes and Drugs highlights the importance of different targets in lead drug discovery and the importance of the synthesis of lead analogues. The book discusses the role of target enzymes, receptors, and related drugs in diabetes mellitus that are necessary for research on improving solutions for diabetes care. This unique resource provides information about all enzymes or receptors involved in diabetes pathophysiology to help describe target enzymes and potent antidiabetic drugs to improve patient care.This type of research is needed for the understanding of the effects of drugs in order to improve future treatments and care of patients with diabetes.

  • The Convergence of Artificial Intelligence (AI) and 6G Communication Networks: The Needs and Implications

    • 1st Edition
    • Volume 139
    • English
    Advances in Computers, Volume 139 focuses on the convergence of Artificial Intelligence (AI) and 6G communication networks, addressing key advancements and implications across various fields. It explores cybersecurity challenges in 5G networks, solutions for 5G performance evaluation, and the transition to 5G-Advanced. The role of AI in enhancing 6G network performance, resource allocation, and management is discussed alongside the technical foundations of 6G and its ability to power edge AI applications. The volume highlights how 6G will transform industries like logistics through automation and AI-driven decision-making, while also covering strategic management perspectives on AI-driven innovations. Sustainability is a key theme, with discussions on energy-efficient cloud and quantum data centers, as well as the integration of green innovations into AI-6G synergy. The metaverse and its reliance on 5G and 6G for immersive experiences are reviewed, alongside the revolutionary potential of quantum computing in 6G networks. The practical applications of AI, such as a CNN-based model for brain tumor detection using 5G edge cloud, and federated learning for 6G, demonstrate the technology's impact on healthcare and data privacy. Additionally, the volume delves into 6G’s role in enabling next-generation metaverse systems and AI-powered telemedicine, while providing insights into the architecture, communication systems, and industrial use cases of 6G. It concludes by summarizing the advancements, advantages, and challenges of 6G, offering a comprehensive view of its future impact on global connectivity.

  • Exploring Noninvasive Disease Biomarkers with Urinary Omics Analysis

    • 1st Edition
    • Arup Giri + 2 more
    • English
    Exploring Noninvasive Disease Biomarkers with Urinary Omics Analysis offers a transformative journey into the world of non-invasive diagnostics. This comprehensive volume delves into the molecular foundations of urinary biomarkers, illuminating the intricate signatures that indicate various pathological conditions and elucidating the mechanisms behind their release into urine. Readers will gain invaluable insights into cutting-edge analytical technologies, methodologies, and data integration techniques essential for biomarker discovery. From genomic approaches to transcriptomics, proteomics, and metabolomics, each chapter provides a thorough examination of the latest advancements, accompanied by practical guidance and case studies showcasing their clinical applications across diverse health conditions.In addition to the foundational knowledge, the book highlights the clinical applications of urinary omics in diagnosing renal disorders, metabolic syndromes, and infectious diseases. It equips professionals and students with the tools needed to navigate the complexities of urinary omics, revolutionize personalized medicine, and advance transformative healthcare solutions. The practical guidance and case studies included in the book make it an invaluable resource for those looking to implement these advanced diagnostic techniques in clinical settings.

  • Carbohydrate Nutrition

    • 1st Edition
    • Bin Zhang + 1 more
    • English
    Carbohydrate Nutrition discusses the nutritional functionality of foods in addressing the current metabolic disease epidemic. It begins by introducing the sources and structures of various carbohydrates, including starch, human milk oligosaccharides, polyols, arabinoxylan, beta-glucan, and cellulose, along with their function in the small intestine and colon. The book offers a comprehensive examination of carbohydrates, covering their chemistry, classification, digestion and health implications. The importance of prebiotic carbohydrates, such as human milk oligosaccharides and dietary fibers like cellulose, arabinoxylans, and beta-glucan is also discussed.Each chapter is authored by leading experts in the field making Carbohydrate Nutrition is a valuable resource for nutrition researchers, food scientists, food chemists, and those studying related topics. Readers can apply these insights to the design and development of foods with improved carbohydrate nutrition.

  • Advances in Agronomy

    • 1st Edition
    • Volume 192
    • English
    Advances in Agronomy, Volume 192, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include The USDA Desert Soil-Geomorphology Project (1957-1972), Electrochemical transformations of nutrients in the soils vis-a-vis geochemistry of potentially and readily available nutrients under different soil moisture regimes: a review, Current approaches in the characterization and quantification of soil crusts, Soil fauna impacts on carbon cycling in managed grasslands: a review, Deciphering PGPR Mechanisms in Saline Soils: Enhancing Plant Productivity, and much more. Other chapters cover Interventions of microbial fuel cell technology for management of agricultural residues: Challenges and future perspectives.

  • The Epidemiology and Prevention of Childhood Injuries

    An Overview
    • 1st Edition
    • Hamid Soori + 1 more
    • English
    The Epidemiology and Prevention of Childhood Injuries: An Overview takes a comprehensive approach to understanding and addressing childhood injuries. Integrating global research and practice, the book aims to significantly advance injury prevention among children. With detailed chapters on epidemiological measures, risk factors, and prevention strategies, it offers a thorough review of childhood injury contexts. The book covers injuries related to transport, home, school, play, sports, workplace, violence, and disasters. It discusses first aid essentials, accountability, and collaboration, concluding with methodologies, data collection techniques, and outcome assessments. This resource is invaluable for researchers, pediatricians, public health experts, and policymakers seeking to protect children.

  • Enzymes of Polyamine Metabolism

    • 1st Edition
    • Volume 715
    • English
    Enzymes of Polyamine Metabolism, Volume 715 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Convergence of MYC and the hypusine circuits in the control of metabolism, HDAC10 structure and enzymology, TR-FRET Assay for Profiling HDAC10 Inhibitors and PROTACs, Polyamine Transport Inhibitors: Methods and caveats associated with measuring polyamine uptake in mammalian cells, Evaluation of platinum drug toxicity resulting from polyamine catabolism, Measurements of acrolein adducts resulting from polyamine catabolism, Alterations in polyamine metabolism induced by the pathogen Helicobacter pylori: implications for gastric inflammation and carcinogenesis, and much more.Other sections delve into Molecular and biochemical analysis of eIF5A, Analysis of in vivo SMOX activity, Structure and role of ATP13A2 in polyamine transport, Analysis of Translational Regulation Using Polysome Profiling and Puromycin Incorporation, Targeting polyamine metabolism in an ex vivo prostatectomy model, Development and characterization of a Drosophila model of SRS, Monitoring ODC activity and polyamines in Bachmann-Bupp syndrome patient biological samples, Gene replacement therapy to restore polyamine metabolism, Investigation of polyamine metabolism in bone homeostasis, Collection, preparation, and biobanking of clinical specimens for polyamine analysis, and many other topics.

  • Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity

    • 1st Edition
    • Volume 121
    • English
    Biosafety Level 4 (BSL4) – Virus Research at the Highest Level of Biosafety and Biosecurity, Volume 121 highlights new advances, with this new volume presenting interesting chapters on highly important topics such as Molecular virulence determinants of human-pathogenic filoviruses, Mucosal Sudan virus infection results in a lethal disease in ferrets with previous Lloviu virus infection not providing cross-protection, Transcriptional signatures of Ebola and Marburg virus infection in a Bat-Immune-System (BIS) mouse model, Divergences in the microbial inactivation pattern between vaporized hydrogen peroxide and aerosolized peracetic acid by dry fogging, and much more.Other chapters cover Molecular expressions in tissues and blood following Reston and Bundibugyo virus infection in swine, De novo rescue of new BSL4 henipaviruses - from sequence to pathogen, Semi-automated diagnostic RT-PCR as a screening assay for antiviral compounds in a 96-well format against highly pathogenic RNA viruses, and Relevance of studying virus – natural reservoir interactions: SNV in deer mice and LASV in Mastomys natalensis.

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