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Elsevier

Books in Life sciences

  • Joll's Diseases of the Thyroid Gland

    • 2nd Edition
    • Francis F. Rundle
    • English
    Joll's Diseases of the Thyroid Gland, Second Edition provides information pertinent to the fundamental aspects of thyroid diseases. This book discusses the physiology structure, and development of the thyroid gland. Organized into 29 chapters, this edition begins with an overview of the function of the thyroid gland to trap and concentrate iodine, harness it in organic combination, and then to secrete it into the blood. This text then discusses the evolutionary scheme showing the development of thyroid gland as a special organ for the control of iodine metabolism. Other chapters consider the various types of thyroid diseases, including simple goiter, acute inflammations, Grave's disease, and granulomatous diseases of the thyroid. This book discusses as well the etiological or clinico-pathological basis of the classification of simple goiter. The final chapter deals with the post-operative complications of thyroidectomy and their treatment. This book is a valuable resource for physicians, surgeons, and clinical researchers.

  • International Review of Forestry Research

    Volume 1
    • 1st Edition
    • John A. Romberger + 1 more
    • English
    International Review of Forestry Research, Volume 1 is a collection of reviews and summaries of world literature concerning defined problem areas in forestry research. This book is composed of seven chapters, and starts with a general survey of the historical development of international forestry research, specifically in Central Europe, since the origin of forest management and of forestry as a science lies on it. This historical development includes historical methods in the practice of forest science, human influences, economics, culture, and laws. The subsequent chapters describe the methods for improvement of forest growth on swamps, the concept of nutrient requirement in forestry, and the methods for determining nutrient requirements of forest trees and stands. These topics are followed by discussions on the biological and environmental aspects of forest site appraisal systems; the anatomy, chemistry, and physiology of bark; and advances in the physiology and biochemistry of tree seeds during maturation, storage, and germination. The concluding chapter considers the development of harmonious control in agricultural, horticultural, and forestry crops, as well as the human influence on regulation and determination of insect populations. This book will prove useful to forest scientists, research workers, teachers, advanced students, administrators, economists, and forest and land managers.

  • Biotechnological Innovations in Animal Productivity

    • 1st Edition
    • BIOTOL + 2 more
    • English
    Biotechnological Innovations in Animal Productivity examines the application of biotechnology to animal production. The book focuses on the use of contemporary biotechnology procedures on the different facets of animal production such as the reproductive capabilities of animals, their growth rates, and the ability of the farmer and veterinary services to prevent and cure infection. The text contains chapters that discuss topics on the manipulation of reproductive processes, endocrine regulation of the oestrous cycle, in vitro embryo production and manipulation, vaccines, and the production of transgenic (livestock) animals. Biotechnologists, biologists, and livestock producers will find the book very insightful.

  • A Guide to Alcohol and Drug Dependence

    • 2nd Edition
    • J. S. Madden
    • English
    A Guide to Alcohol and Drug Dependence, Second Edition provides information on the recognition of alcohol misuse, on alcohol dependence among the elderly, and on outpatient withdrawal from opioids. This book emphasizes the detection and early treatment of alcohol misuse, the detoxification of drug users followed by drug-free counseling, and preventive measures. Organized into nine chapters, this edition begins with an overview of the various types of dependence-producing drugs, including morphine, cocaine, cannabis, alcohol-barbiturate, amphetamine, hallucinogen, and inhalants and volatile solvents. This text then explains the depressant actions of alcohol on the central nervous system that affects first the higher cerebral functions responsible for concern about personal behavior and for self-restraint. Other chapters consider the physical disabilities that heavy drinkers are prone to develop. The final chapter deals with the preventive measures directed against the problems presented by drugs and alcohol. This book is a valuable resource for social workers, nurses, occupational therapists, and clinical psychologists.

  • Plant Pests and their Control

    • 1st Edition
    • Peter G. Fenemore
    • English
    Plant Pests and their Control, Revised Edition discusses the concepts involved in pest management, along with its application, constraints, and opportunities. This book is comprised of 13 chapters that cover topics relevant in understanding the basis and practice of pest management. The first six chapters deal with the various aspects of entomology. These chapters cover the importance of insects; the physiological properties of insects; and reproduction and life cycle. The next chapter covers the non-insect pests. Chapter 8 discusses the relationship between insects and plants, while Chapter 9 covers the mortality factors of insect, such as predators, parasites, and pathogens. The next chapter presents the ecological background of pest control. The remaining three chapters discuss pest management itself. This text will be of great use to agriculturists, horticulturalists, and pest control professionals. Household owners dealing with residential pest infestation will also find this book a great source of information.

  • Recent Progress in Hormone Research

    Proceedings of the 1966 Laurentian Hormone Conference
    • 1st Edition
    • Gregory Pincus
    • English
    Recent Progress in Hormone Research, Volume 23 is a collection of papers presented at the 1966 Laurentian Hormone Conference, held at Mont Tremblant, Quebec, Canada. This conference explores four major areas of research, including thyroid physiology, thyroid hormones, contemporary developments in peptide hormone chemistry and biochemistry, and special studies of insulin, particularly in man. This book is organized into four parts encompassing 14 chapters. Part I deal with the factors controlling thyroid stimulation and special studies of the mode of action of thyroid hormones, including antithyroid drugs. Part II describes the mode of action of steroid hormones and hormonal steroids based on the effects on normal and neoplastic tissues. This part also looks into a definitive segment of research in endocrinology with the metabolism of the steroid hormones in vivo and in vitro. The discussion of an important clinical condition involving adrenocortical steroid production is given in the chapter concerned with congenital adrenal hyperplasia. Parts III and IV explore the synthesis of peptide hormones and insulin. These parts also tackle the gastrointestinal hormone biochemistry, the detection of at least two insulin-like activities in human serum, and the particular control of insulin activity in man. This book is directed primarily toward endocrinologists.

  • International Review of General and Experimental Zoology

    Volume 3
    • 1st Edition
    • William J. L. Felts + 1 more
    • English
    International Review of General and Experimental Zoology, Volume 3 reviews various topics related to general and experimental zoology, including the epigenetic mechanisms of patterns in the insect integument and the enteric plexus of mammals. The role of macrophages in the induction of the immune response and the metabolism of mammalian ova are also explored, together with the structure of gallbladder epithelium and cell types in the mammalian thyroid gland. Comprised of eight chapters, this volume first discusses the problem of supracellular pattern formation in the insect cuticle and its complexity and unknown nature, with emphasis on the cuticular patterns of the various zones of the cockroach antenna. The reader is then introduced to the enteric plexus of mammals and its components, along with the relationship of the innervation of the gut to the autonomic nervous system. Subsequent chapters focus on the role of macrophages in the induction of the immune response; metabolism of mammalian ova; structure of gallbladder epithelium; and the goblet cells, Paneth cells, and basal granular cells of the epithelium of the intestine. The book also considers cell types found in the mammalian thyroid gland before concluding with an assessment of the use of electron microscopy in elucidating the structure and function of the placenta. This monograph should prove useful to practicing zoologists and graduate and undergraduate students of zoology.

  • Human Chromosome Methodology

    • 1st Edition
    • Jorge J. Yunis
    • English
    Human Chromosome Methodology fills the need for an authoritative and up-to-date treatise which would serve as a text and reference for advances in human cytogenetics. The book includes readily comprehensible chapters that cover each phase of laboratory investigation from the preparation of materials for sex chromatin and chromosome techniques for bone marrow, blood, skin, and gonadal specimens to the subject of autoradiography and chromosome identification. Included also are guides to microscopy and photomicrography as well as an up-to-date treatment of chromosomes in disease. It is hoped that this volume will serve as an adequate guide to laboratory techniques and their applications for research workers, students of genetics, and members of the medical profession involved in setting up a laboratory of cytogenetics.

  • Physiology of Echinoderms

    International Series of Monographs in Pure and Applied Biology Zoology
    • 1st Edition
    • John Binyon
    • G. A. Kerkut
    • English
    Physiology of Echinoderms is an 11-chapter book that begins by elucidating the feeding, digestion, and excretion of specific echinoderms. The critical role of amoebocytes in the excretion process involved in these organisms is also explained. This book also describes several aspects of importance to these organisms, including salinity tolerance, osmoregulation, ionic regulation, chemical composition, neural control of locomotion, biochemical affinities, toxins, and immunology. The organisms' physiology in sensory, water vascular system, respiratory system, spawning, neurosecretion, nerves, and muscles are also explained.

  • The Toxicology of Radioactive Substances

    Volume 3.59
    • 1st Edition
    • A. A. Letavet + 1 more
    • English
    The Toxicology of Radioactive Substances, Volume 3: Iron-59 deals with the experimental results of tests conducted at the Radiotoxicology Laboratory of the Institute of Occupational Hygiene and Disease, Academy of Medical Sciences, U.S.S.R. The book focuses on studies made on iron-59, which is widely used in science and technology, such as in the metal industry and in the research of hemoglobin metabolism in the bone marrow and red cells. Other studies show, however, that there is a long-term detrimental effect of intake of iron-59. The text then gives a brief outline of the physical, chemical, and biological properties of iron. Research also shows that the body's reaction to radioactive substances depends on how these are transmitted to the body and on their physicochemical properties. The effect of prolonged administration of radioactive iron on the electrical activity of the cerebral cortex of animals is analyzed, of which, possibly, the nervous system is most affected. The book notes also the changes in the red blood cells during chronic administration of iron-59 in small doses, wherein the hemoglobin levels increased temporarily. Studies of prolonged exposure to radioactive isotopes during pregnancy of the test animals show that there are significant changes in erythropoiesis, associated with iron deficiency. In another study, the prolonged internal administration of radioactive substances showed phasic changes in the height of electrocardiographic waves of the test animals. The text is suitable for physicists, nuclear scientists, doctors of toxicology, and researchers in nuclear medicine.

  • Symposium on Clinical Pharmacology

    Biochemical Pharmacology
    • 1st Edition
    • William A. Creasey + 2 more
    • English
    Symposium on Clinical Pharmacology reviews advances in clinical pharmacology, with emphasis on how to materially improve the efficacy of cancer chemotherapy. Topics range from absorption, protein binding, distribution, and excretion of antineoplastic drugs to factors affecting the biotransformation and activity of antitumor drugs. The transport of tumor-inhibitory agents across cell membranes is also examined, together with factors influencing drug selectivity and the mechanisms of clinical drug resistance. This volume is comprised of 23 chapters and begins with a brief summary of the different kinds of pharmacokinetic models and how detailed kinetic investigations of a drug in animals may provide further insight into modes of its clinical use. The next chapter considers the chief factors in determining the effective concentration of a drug at a receptor site as well as the duration and intensity of drug effect, citing antineoplastic agents as examples. The role of enzymatic activation and inactivation in drug selectivity is also discussed, along with the general mechanisms of clinical resistance to cancer chemotherapy; biochemical and pharmacological principles of combination chemotherapy; and the reaction and effects of nitrosoureas. This book will be of interest to clinicians, pharmacologists, and biochemists.

  • Hormones and Human Breast Cancer

    An Account of 15 Years Study
    • 1st Edition
    • John Hayward
    • V. G. Allfrey + 2 more
    • English
    Recent Results in Cancer Research: Hormones and Human Breast Cancer provides information pertinent to the fundamental aspects of breast cancer and hormones. This book discusses the endocrine factors involved in breast cancer. Organized into two parts encompassing 11 chapters, this book begins with an overview of the process of castration as an effective therapeutic measure in many pre-menopausal patients with advanced breast cancer. This text then discusses the response rate following ablation wherein only 60 percent of patients subjected to hormone therapy as a first treatment for recurrence will survive to ablation. Other chapters consider the microscopical features of a tumor. This book discusses as well the prescription of corticosteroids as treatment, which originates from the mechanism of response that followed adrenalectomy or hypophysectomy. The final chapter deals with the use of radio-immunoassay methods in treating breast cancer. This book is a valuable resource for biochemists, scientists, and physicians.

  • Chemical Structure–Biological Activity Relationships: Quantitative Approaches

    Proceedings of the 3rd Congress of the Hungarian Pharmacological Society, Budapest, 1979
    • 1st Edition
    • F. Darvas
    • English
    Chemical Structure-Biological Activity Relationships: Quantitative Approaches, Volume III, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. This volume focuses on the methodological aspects of QSAR. It also aims to inform the reader about the QSAR research conducted in East-European countries. This volume contains 38 presentations organized into six sections. Several lecturers deal with ""real prediction"" cases, i.e. activity estimation prior to the synthesis of the compounds. A particularly abundant section is devoted to the question of how the receptor models can be built up by means of QSAR calculations. Other sections present mathematical models and algorithms which could be applied to improve further the effectiveness of QSAR calculations. As another unique feature, a separate section treats the quantitative aspects of peptide structure-activity relationships—a field seemingly backward despite its evident importance. Hydrophobicity and its influence on biological potency along with the relationship of steric properties and biological activity are also discussed.

  • Evaluation of Drug Activities

    Pharmacometrics
    • 1st Edition
    • D R Laurence + 1 more
    • English
    Evaluation of Drug Activities: Pharmacometrics, Volume 2 provides information pertinent to the fundamental aspects of pharmacometrics. This book covers a variety of topics, including anticholinesterases, antitussives, cardioactive agents, diuretics, dermatological agents, and estrogens. Organized into 21 chapters, this volume begins with an overview of anticholinesterases and its pharmacological and physiological actions. This text then examines the diversity of methods for evaluating antitussive drugs, which is related to the complexity of cough reflexes. Other chapters consider tests for cardioactive substances of three general classes, namely, the cardiac glycosides, the coronary vasodilators, and the anti-arrhythmics. This book discusses as well the introduction of many diuretics into therapeutic practice during the past years bears witness to the convenience and success of the tests available for assessing drugs of this class. The final chapter deals with drugs affecting lipid levels in plasma. This book is a valuable resource for chemists, physiologists, pharmacologists, and clinicians.

  • The Molecular Properties and Evolution of Excitable Cells

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • C. J. Duncan
    • G.A. Kerkut
    • English
    The Molecular Properties and Evolution of Excitable Cells describes the theoretical aspects in which excitable cells, such as nerves, muscles, and sense organs, operate. This book develops a hypothesis regarding the evolution and characteristics of excitable cells. This monograph focuses on the properties of the bounding membrane and its complex permeability system, which starts the excitation state. Sense organs, as the input component in both vertebrates and invertebrates, are then discussed. The text then briefly describes the ways that the ionic permeability of the excitable membrane can both be modified and controlled. The book points out that since ions pass through standard sizes of the pores in an excitable membrane, their passage is determined by the dimensions of the pore and by the existing charge found on its walls. The book then explains the application of a mechanical stimulus to a mechanoreceptor that will cause deformations in the membrane. This deformation leads to enzyme activity and produces alteration in the rate at which ATP is supplied to the lateral borders of the cell. The text discusses a hypothesis that invokes enzyme activity by propagating action potential along the axon, and other input systems, such as adrenaline, amino acids, and y-amino-butyric acid (GABA). The book also explains the hypothesis that living organisms are composed of an ordered system of protein-enzymes forming on phospholipid-protein membranes. This monograph will benefit microbiologists, biotechnologists, and academicians connected with the biological sciences.

  • Kinetic Theory of Nonideal Gases and Nonideal Plasmas

    International Series in Natural Philosophy
    • 1st Edition
    • Yu L Klimontovich
    • D. ter Haar
    • English
    Kinetic Theory of Nonideal Gases and Nonideal Plasmas presents the fundamental aspects of the kinetic theory of gases and plasmas. The book consists of three parts, which attempts to present some of the ideas, methods and applications in the study of the kinetic processes in nonideal gases and plasmas. The first part focuses on the classical kinetic theory of nonideal gases. The second part discusses the classical kinetic theory of fully ionized plasmas. The last part is devoted to the quantum kinetic theory of nonideal gases and plasmas. A concluding chapter is included, which presents a short account of the kinetic theory of chemically reacting systems and of partially ionized plasmas, in order to espouse further studies in the field. Physicists, scientific researchers, professors, and graduate students in various fields will find the text of good use.

  • Blood

    • 1st Edition
    • Walter S. Root + 1 more
    • English
    Physiological Pharmacology, Volume V: Blood describes the interrelationships between pharmacology and blood. This volume is organized into five parts encompassing 16 chapters that consider the effect of therapeutic agents on the physiology of blood, whether it be coagulation, the white cells, red cells, or platelets. The opening part deals first with the physiology of blood coagulation and the mode of action of anticoagulants. This part also covers the mechanism of thrombogenesis and thrombolysis, as well as the in vivo actions of thrombolytic agents. The subsequent parts initially examine the biochemistry and physiology of platelets, hematopoietic stem cells, and white cells. These topics are followed by discussions of the mechanism of thrombocytosis and clinical manifestations of thrombocythemia, as well as the mechanisms of immunologic drug effect on blood cells. These parts also explore the effects of drugs on myelopoiesis and the physiological and immunological activities of lymphocytes. The closing part reviews the iron, vitamin B12, folic acid, erythropoietin, and transferrin components of red blood cells. This part also examines the mechanism of erythropoietic cellular proliferation and the initiation of hyperoxia. This book is intended primarily to physiological pharmacologists, hematologists, and researchers.

  • Clinical Neuroendocrinology

    • 1st Edition
    • G. M. Besser + 1 more
    • English
    Clinical Neuroendocrinology, Volume II discusses neuroendocrine science and its application to the analysis of human physiology and behavior. This book stresses the importance of the interrelationships between central and peripheral signals, neurotransmitters and neuromodulators, and target glands and peripheral tissues to ensure coordination of somatic and behavioral development and function. The ""centralist"" concepts of the importance of brain hormones are revised in this text, emphasizing that neurohumoral factors isolated from brain tissues, and initially considered to be primarily involved in the central nervous system regulation of the endocrine system, also exist outside the brain and spinal cord. This volume is valuable to neuroendocrinologist... but is also a good source for those involved in basic and clinical research and patient management.

  • The Pathogens, the Infections, and the Consequences

    Diseases Caused by Protista
    • 1st Edition
    • David Weinman + 1 more
    • English
    Infectious Blood Diseases of Man and Animals: Diseases Caused by Protista, Volume II: The Pathogens, the Infections, and the Consequences focuses on the study of metabolic, immuno-pathologic, taxonomic, ultrastructural, locomotor, ecologic, zoonotic, and other features of the protistan blood diseases. The book first discusses the diseases of particular interest to man, including bartonellosis, malaria, and human trypanosomiases. Topics include types of human infection, pathology and pathogenesis, immunology, chemotherapy, transmission and epidemiology, human and simian malaria, and geographical distribution and prevalence. The publication also ponders on Trypanosoma (Schizotrypanum) cruzi infection, as well as pathology, pathogenesis, immunology, and transmission. The manuscript elaborates on relapsing fevers, babesiosis, theileriasis, and trypanosomiasis. Discussions focus on development in tick vector, resistance, prevention and control, clinical syndrome, chemotherapy, and immunity and immunization. The text is a valuable reference for students interested the diseases caused by Protista.

  • Introduction to Floriculture

    • 1st Edition
    • Roy A. Larson
    • English
    Introduction to Floriculture provides an introduction to commercial floriculture, containing information on major and minor greenhouse and field crops, and includes potted plants and cut flowers. The book is organized into two parts. Part I on cut flowers discusses the history and propagation of chrysanthemums, carnations, roses, snapdragons, orchids, gladiolus, and minor cut crops. Part II on potted plants includes bulbous plants, azaleas, pot mums, African violets, poinsettias, and Easter lilies. This book was written for students who have been exposed to a sufficient number of biology courses to acquaint them with many of the terms and plant processes discussed in the text. It would be beneficial if they have also taken a course in greenhouse management or are taking one concurrently with their floriculture course. The book can be used by commercial growers who constantly seek more information to enable them to realize maximum gain from the investments of labor, time, and capitol they have placed in this challenging field.

  • Histological Techniques for Electron Microscopy

    • 2nd Edition
    • Daniel C. Pease
    • English
    Histological Techniques for Electron Microscopy, Second Edition, offers a practical guide for those who would study cells or tissues with an electron microscope. The book contains 11 chapters and begins with a discussion of the organization and management of an electron microscope laboratory. This is followed by separate chapters on tissue preservation; fixatives and their variations; methacrylate embedding and cross-linked plastics, microtomes and microtomy; and section mounting. Subsequent chapters deal with the techniques of "staining" for electron microscopy, photography; mounting, shadowing, and replication; and negative staining.

  • Physiology and Toxicology of Male Reproduction

    • 1st Edition
    • James C. Lamb + 1 more
    • English
    Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

  • An Introduction to Mechanisms in Pharmacology and Therapeutics

    • 1st Edition
    • Howard Rogers + 1 more
    • English
    An Introduction to Mechanisms in Pharmacology and Therapeutics aims to provide some extra information and background reading on modes of action of drugs, but it is not meant to replace existing pharmacology textbooks. It also attempts to show the connection between cell biology and the practice of clinical medicine. This book is organized into 13 chapters that discuss drug-receptor interactions and the influence of drugs on the nervous, respiratory, circulatory, and alimentary systems. They also explain the concepts of pharmacogenetics, intracellular control mechanisms, chemotherapy, and the different types of drugs. This book will be of interest to preclinical and clinical medical students and those preparing for Bachelor of Science degree in Pharmacology and others interested in understanding how drugs work.

  • Neurological Emergencies

    • 1st Edition
    • S.D. Shorvon
    • English
    Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

  • Toxic Interactions

    • 1st Edition
    • Robin S. Goldstein + 2 more
    • English
    Toxic Interactions is a collection of papers that discusses the basic principles behind the mechanism of toxicological interactions. This book deals with interacting chemicals and their effects on certain exposed organs or molecules. Concerning discussion of the principles, contributed papers explain the role of xenobiotic biotransformation processes in inactivating reactive intermediates of toxicants. Other authors discuss the effects of endogenous molecules and the consequences of chemically induced depletion of protective agents, as well as the pharmacokinetic principles that affect chemical interactions. Several authors also review experiments on the types of chemicals that produce or increase the degree of toxicity. The text reviews the results of liver and kidney injuries from exposure to two or more chemicals, while other papers focus on lung and heart toxicity. For example, direct mechanism of cardio toxicity includes toxicity due to an increase in plasma concentrations of the compound, or as in latent cardiac toxicity that is a product of another action on another system of organs. Professors in pharmacology, practitioners of general medicine, specialists or researchers dealing with microchemistry, toxicology or drug therapy will find this reference valuable.

  • Andreas Vesalius Bruxellensis

    The Bloodletting Letter of 1539: An Annotated Translation and Study of the Evolution of Vesalius's Scientific Development
    • 1st Edition
    • John B. De C. M. Saunders + 1 more
    • English
    Andreas Vesalius Bruxellensis: The Bloodletting Letter of 1539 provides an insight into the knowledge of anatomy in that period. This book presents an overview of the development of the practice of venesection. This text discusses the discovery of the venous valves in the human body. Vesalius points out in this text the anatomical basis for the employment of phlebotomy. This book is liberally annotated to guide the readers. Medical historians will find this book extremely useful.

  • Case Presentations in Heart Disease

    • 2nd Edition
    • Alan Mackintosh
    • English
    Case Presentations in Heart Disease: Second Edition presents cases dealing with the diagnosis and treatment of patients with a heart related problem. This book addresses the need for a sample of real life cardiologic problems. Some of the topics covered in the book are the case of the 63-year-old brewery worker with severe pain between the shoulder blades; a case of a 54 years old woman with pain in her right loin; a case of a man applying for insurance; and a case of a married man who experienced loss of consciousness lasting 5 minutes. Other topics discussed include the causes of dissecting aortic aneurysm, the diagnosis made on the female with pain in her right loin, and the development of atrial myxomas. The acute phase of a myocardial infarction is presented. The concluding part is devoted to the analysis of a case of coughing symptom with no smoking history. The book can provide useful information to doctors, cardiologists, students, and researchers.

  • The Thermohaline Finestructure of the Ocean

    Pergamon Marine Series
    • 1st Edition
    • K. N. Fedorov
    • J. C. Swallow
    • English
    The Thermohaline Finestructure of the Ocean is a five-chapter text that describes the fine-scale stratification phenomenon in the ocean and the physical processes that participate in its formation and govern its evolution. After an introduction to the concept of thermohaline finestructure of the ocean, this book goes on presenting some methodological aspects in connection with the finestructure measurements in the ocean. The next chapters examine the complex interrelations between the fine-scale stratification of the ocean water. The remaining chapters explore several important physical processes, such as molecular diffusion, convection, turbulence, internal gravity waves, inertial motions, and mean currents. This book is written for physical oceanographers and specialists in other related branches of research.

  • Progress in Chemical Toxicology

    Volume 3
    • 1st Edition
    • Abraham Stolman
    • English
    Progress in Chemical Toxicology, Volume 3 explores the developments in methods and instrumentation for toxicological analyses. This book is composed of eight chapters, and begins with a description of the pharmacologic and physiologic effects of aliphatic alcohols. The succeeding chapter deals with the methods of analysis of various volatile poisons, such as halogenated aliphatic compounds, aromatic hydrocarbons, and acid compounds. A chapter focuses on the methods of determination and classic procedures for carbon monoxide analysis in breath and blood. These topics are followed by discussions on the development of spectrochemical methods chemical and radiochemical methods of determination of radionuclides in human bones and tissues; and the toxic effects of combined drug action. The last chapter examines the poison residue occurrence in human tissues. This book is of great value to toxicologists and public health workers and researchers.

  • Receptors in the Human Nervous System

    • 1st Edition
    • F. A. O. Mendelsohn + 1 more
    • English
    Receptors in the Human Nervous System is a synthesis of the results of receptor mapping by leaders in the field. In addition to a comprehensive discussion of the distribution and possible interactions of the receptors of different neuroactive substances, this book also contains an abundance of pictorial representations of receptor distributions. High-quality photographs of one receptor are often juxtaposed with photographs of the distribution of a different receptor or receptor subtype for the consideration of possible interactions between different systems. The book surveys the distribution of receptor subtypes for the classical monoamine transmitters (acetylcholine, adrenaline, noradrenaline and serotonin) as well as the distribution of receptors for the excitatory and inhibitory amino acids, (glutamate, GABA and benzodiazepines) as well as the opioid peptides, angiotensen and other neuropeptides. The distribution of multiple types of serotonin receptors is given in detail, and the codistribution of receptors in the cortex is discussed. The book is directed toward researchers in the field of chemical neuroanatomy, as well as pharmacologists, neurophysiologists, and neuroscientists.

  • Diagnostic Reference Index of Clinical Neurology

    • 2nd Edition
    • Pasquale F. Finelli
    • English
    Diagnostic Reference Index of Clinical Neurology aims to give the busy clinician a fast, easy-to-use guide to the core neurological literature published from 1980 to 1986. This book is divided into two sections, key words and references. The keywords section consists of neuroscience terms and each main entry is followed by reference citation numbers and corresponding references. This index, unlike the usual computerized systems for literature retrieval, is structured around clinical problems and uses the approach and terminology of a practicing neurologist. The contents were sources from the full text of articles that were published in critical core of fourteen major international English-language journals in medicine and neurology. This book will be of interest to neurology students and to practicing clinical neurologists.

  • Fetal Endocrinology

    • 1st Edition
    • Miles J. Novy + 1 more
    • English
    Fetal Endocrinology covers many facets of primate reproductive biology. The book discusses some thoughts on the fetoplacental unit and parturition in primates; the development and function of the human fetal adrenal cortex; and postnatum evolution of the adrenal glands of rhesus macaques. The text also describes the regulation of fetoplacental steroidogenesis in rhesus macaque; the comparative biological, immunologic, and chemical properties of the primate chorionic gonadotropins; and urinary estrogens during pregnancy in diverse species. The secretion and physiology of chorionic somatomammotropin in primates; the placental thyroid stimulators and thyroid function in pregnancy; and growth factors in fetal growth and development are also considered. The book further tackles the production and activity of placental releasing hormone; the endocrinology of parturition; and sex-determining genes and gene regulation. The text also looks into the testicular hormone production in fetal rhesus macaque; the control of pituitary gonadotropin secretion in fetal rhesus macaque; and the development of the regulatory mechanisms of the hypothalamic-pituita... system in the human fetus. The development of the fetal adrenals in nonhuman primates and perspectives in fetal endocrinology are also encompassed. Reproductive physiologists, pediatricians, gynecologists, and endocrinologists will find the book invaluable.

  • Recent Advances in Animal Nutrition 1988

    • 1st Edition
    • W. Haresign + 1 more
    • English
    Recent Advances in Animal Nutrition 1988 focuses on how feeds affect animal nutrition. The book first discusses problems of raw ingredient variability; European legumes in diets for non-ruminants; and the implications of vitamin E and free radical formation for animal nutrition. The text also underscores approaches to enhance growth in pigs. Growth hormone injection, enzyme supplementation, somatostatin immunization, and probiotics are noted. The book then highlights the nutritional requirements of turkeys to meet market demands. Early bodyweight and subsequent growth rate; nutrition and meat yields; commercial recommendations; and traditional farm-fresh turkeys are discussed. The text also discusses the mineral and trace element requirements of poultry; response of laying hens to energy and amino acids; and prediction of the metabolizable energy content of compound feeds and nutrient allowances for ruminants. The selection is a vital source of data for readers interested in studying animal nutrition.

  • Measure for Measure

    • 1st Edition
    • Elizabeth O'Reilly
    • English
    Measure for Measure is a compilation of carefully selected recipes to give the best of home cooking. This text serves as a guide to healthy and delicious food preparation. The book has more than 350 recipes on soups, fish, meat, and vegetables, where carbohydrate and caloric content for single servings are presented for each dish. Some chapters are devoted to desserts, eggs and cheeses, sauces, and the baking of bread and pastries. The book also has a chapter that discusses wines, a table for converting Metric to English measures, a special chapter on cooking with artificial sweeteners, and a glossary of culinary terms. Cooks, culinary students, diabetics, weight watchers, dietitians, and those who simply love to cook will find this book a very good reference.

  • Evolution

    Evolution
    • 1st Edition
    • Volume 10
    • E. R. Trueman + 1 more
    • English
    FROM THE GENERAL PREFACE: This multivolume work, The Mollusca, had its origins in the mid 1960s with the publication of two volumes entitled Physiology of Mollusca and edited by Wilbur and Yonge. In those volumes, 27 authors collaborated to summarize the status of the conventional topics of physiology as well as biochemistry, reproduction and development, and ecology. Within the past two decades, there has been a remarkable burgeoning of molluscan research generally and with it the development of new fields of investigation. During the same period, several excellent books on molluscs have appeared. However, they do not provide adequate information on the many recent advances or give the breadth of perspective of current knowledge of the phylum. Clearly, there was need for a larger work with a comprehensive treatment of major areas of molluscan research. The Mollusca, as a series of 12 volumes, attempts to fulfill this objective. Even here, practical considerations have meant that certain aspects of molluscan research have not been included.Each major area is treated by several authors, each reviewing his or her special field. The areas are structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. Throughout, the authors have given emphasis to recent advances and present status of molluscan biology. In so doing, directions of future research have become evident.The Mollusca is intended to serve several disciplines--zoology... biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs.FROM THE PREFACE TO VOLUME 10: Recent events that have stimulated a great surge of investigation into the evolution of the Mollusca include the discovery of well-preserved microscopic molluscs at most levels of the Cambrian on five continents, the development of electron microscopy, the need to examine competing models of the early history of the phylum, new interest in interstitial fauna of littoral and near-littoral sands, and significant advances in our knowledge of shell ontogeny, construction, and evolution. It is timely that an up-to-date synthesis involving both paleontologists and zoologists should be published after a decade of such activity and advance when many of the long-held views on molluscan phylogeny have been overturned.This book deals with all molluscan classes except the Cephalopoda, which will be treated in Volume 12. The two books together provide an up-to-date introduction to the evolution of the Mollusca with adequate references to guide further work. They will be invaluable to specialists on molluscs, postgraduate research workers, and undergraduates with particular interests in this phylum. Authorities on the various molluscan groups were asked to express their views and to treat the subject as they wished; the book provides a valuable record of their opinions at this time.While the main groups are broadly and fully treated, focus has been narrowed toward a few selected minor groups of particular interest such as limpets, land snails, and the Anomalodesmata, in which recent work has been particularly significant.Because recent years have seen major revisions in classificatory terms, the editors have provided an outline classification into which the chapter topics fit.

  • Ultrastructural Pathology of the Cell and Matrix

    A Text and Atlas of Physiological and Pathological Alterations in the Fine Structure of Cellular and Extracellular Components
    • 3rd Edition
    • Feroze N. Ghadially
    • English
    Ultrastructural Pathology of the Cell and Matrix: Third Edition Volume I present a comprehensive examination of the intracellular lesion. It discusses the analysis of pathological tissues using electron microscope. It addresses the experimental procedures made on the cellular level. Some of the topics covered in the book are the physiological analysis of the nucleus; nuclear matrix, interchromatin, and perichromatin granules; structure and function of centrioles; characteristics of mitochondria; Golgi complex in cell differentiation and neoplasia; and degranulation of rough endoplasmic reticulum. The intracytoplasmic and intranuclear annulate lamellae are fully covered. An in-depth account of the classification, history, and nomenclature of lysosomes are provided. The morphology and normal variations of melanosomes and anchoring fibrils are completely presented. A chapter is devoted to the endocytotic structures and cell processes. Another section focuses on the classification and nomenclature of fibrous components. The book can provide useful information to cytologists, scientists, students, and researchers.

  • Energy Metabolism

    Proceedings of the Eighth Symposium on Energy Metabolism Held at Churchill College, Cambridge, September, 1979
    • 1st Edition
    • Laurence E. Mount
    • English
    Studies in the Agricultural and Food Sciences: Energy Metabolism is a compilation of works on the energy metabolism in animals, especially animals of agricultural importance. The book is written by authoritative workers in the field and is divided into six parts; each chapter is based on a selected paper presented at the Eighth Symposium on Energy Metabolism held at Cambridge in September 1979. The text discusses feed evaluation; use of energy for maintenance and growth; and simulation models for energy exchange and growth. The book also covers the comparative aspects of energy metabolism; use of energy in production and lactation; and metabolic responses in the growing animal. The monograph is recommended for those who plan to study about energy metabolism of farm animals and its relationship with certain biological processes. The book will also appeal to those who develop feeds and methods that can help improve energy metabolism of farm animals.

  • Presynaptic Receptors and Neuronal Transporters

    Official Satellite Symposium to the IUPHAR 1990 Congress Held in Rouen, France, on 26–29 June 1990
    • 1st Edition
    • S.Z. Langer + 2 more
    • English
    Advances in the Biosciences, Volume 82: Presynaptic Receptors and Neuronal Transporters documents the proceedings of the Official Satellite Symposium to the IUPHAR 1990 Congress held in Rouen, France on June 26-29, 1990. The first part of this book deals with the extensive and still increasing list of presynaptic release-modulating auto and heteroreceptors, emphasizing the various subtypes of presynaptic receptors that are characterized by functional studies, both in vitro and in vivo, using a number of experimental approaches. The next chapters are devoted to the molecular pharmacology of presynaptic receptors, of which can interfere with G proteins and modify the activity of adenylate cyclase, guanylate cyclase, or protein kinase C. The purification and molecular biology of transporter systems, including cloning and sequencing of the neuronal sodium-ion coupled GABA transporter are also discussed. This compilation concludes with insights on the function of presynaptic receptors and neuronal transporters both in the periphery and in the CNS, as well as their ubiquitous locations and physiological roles. This publication is a good reference for students and individuals researching on the presynaptic autoreceptors and neurotransmitters.

  • In Vitro Biological Systems

    Methods in Toxicology, Vol. 1
    • 1st Edition
    • Charles A. Tyson + 1 more
    • English
    Methods in Toxicology, Volume 1: In Vitro Biological Systems, Part A provides basic techniques employed by widely recognized scientists to prepare and maintain the biological components of in vitro model systems. The book discusses the in vitro models of neural and neuromuscular systems; ocular system; respiratory system; cardiovascular system; and gastrointestinal system. The text also describes liver slices; liver hepatocytes; other liver cell systems; proximal tubule fragments; kidney cell culture; reproductive and developmental systems; immune system; and skin. Pharmacologists, toxicologists, cell biologists, physiologists, immunotoxicologists, and molecular toxicologists will find the book invaluable.

  • The Toxicology of Aflatoxins

    Human Health, Veterinary, and Agricultural Significance
    • 1st Edition
    • David L. Eaton + 1 more
    • English
    Aflatoxins, natural fungal toxins found in foods and animal feeds, have great public health significance. This book presents the basic and applied toxicology of aflatoxins, including analytical identification, agricultural and veterinary implications, toxicology and carcinogenesis in humans, and economic and regulatory problems associated with aflatoxin contamination and control.

  • Neurobiology of Steroids

    • 1st Edition
    • Volume 22
    • P. Michael Conn + 1 more
    • English
    Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions.

  • Advances in Drug Delivery Systems, 6

    Proceedings of the Sixth International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, U.S.A., February 21-24, 1993
    • 1st Edition
    • James M. Anderson + 2 more
    • English
    Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology. The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes. The book examines the factors on in vitro micelle stability of adriamycin-block copolymer conjugates; vaginal and reproductive system treatments using a bioadhesive polymer; and control of the disposition profiles of proteins in the kidney via chemical modification. The publication also takes a look at drug delivery using biodegradable microspheres; approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer; and biodegradable microspheres for the delivery of oral vaccines. The selection is a valuable source material for scientists and readers interested in the advances in the systems of drug delivery.

  • Neural Modeling and Neural Networks

    • 1st Edition
    • F. Ventriglia
    • English
    Research in neural modeling and neural networks has escalated dramatically in the last decade, acquiring along the way terms and concepts, such as learning, memory, perception, recognition, which are the basis of neuropsychology. Nevertheless, for many, neural modeling remains controversial in its purported ability to describe brain activity. The difficulties in "modeling" are various, but arise principally in identifying those elements that are fundamental for the expression (and description) of superior neural activity. This is complicated by our incomplete knowledge of neural structures and functions, at the cellular and population levels. The first step towards enhanced appreciation of the value of neural modeling and neural networks is to be aware of what has been achieved in this multidisciplinary field of research. This book sets out to create such awareness. Leading experts develop in twelve chapters the key topics of neural structures and functions, dynamics of single neurons, oscillations in groups of neurons, randomness and chaos in neural activity, (statistical) dynamics of neural networks, learning, memory and pattern recognition.

  • Electron-Microscopic Structure of Protozoa

    International Series of Monographs on Pure and Applied Biology: Zoology
    • 1st Edition
    • D. R. Pitelka
    • G. A. Kerkut
    • English
    Electron-Microscopic Structure of Protozoa mainly discusses the structure and taxa of protozoa. This text first discusses protozoa as cells, wherein the author emphasizes that these unicellular organisms be compared with a whole metazoan organism than with any of its component cells. This book then studies the protozoan superclass Rhizopoda, subphylum Actinopoda, slime molds, and subphylum Sporozoa, as well as toxoplasma. Phytoflagellates, zooflagellates, and ciliates are also tackled. This book concludes by explaining membrane differentiations, fibrous structures, and relationships of protozoa. This publication will be invaluable to biologists and other scientists interested in studying protozoa.

  • Essays in Toxicology

    Volume 6
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 6 approaches toxicology by very different routes; two essays with materials (plastics and tobacco alkaloids), one deals with the effects of abnormal pressure, one considers the biochemistry of the lung, and one discusses poison control centers and other mechanisms for limiting the injury done by toxic materials. The book presents essays on the topological problems and untoward effects from plastic devices used in medical applications; the metabolism of tobacco alkaloids; and poisons control center. The text also includes essays on the toxicology of hypobaric and hyperbaric environments; as well as the exploitable biochemical approaches for the evaluation of toxic lung damage. Biochemists, physical chemists, neurophysiologists, epidemiologists, and social scientists will find the book invaluable.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 2
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume II covers the design of bioactive compounds interacting with enzymes and playing a role in enzyme synthesis. The book discusses the modulation of pharmacokinetics by molecular manipulation; the factors in the design of reversible and irreversible enzyme inhibitors; and the design of organophosphate and carbamate inhibitors of cholinesterases. The text also describes the design of reactivators for irreversibly blocked acetylcholinesterase... drug design based on the inhibition of protein synthesis in the context of susceptible enzymic reactions; as well as the role of enzymes and their synthesis as a target for antibiotic action. The rational design of antiviral agents; the design of penicillin; the design of peptide hormone analogs; as well as the advances in the design of diuretics are also considered. The book further tackles the design of biologically active steroids; the rational elements in the development of superior neuromuscular blocking agents; and the design of tumor-inhibitory alkylating drugs. Pharmacologists, chemists, and people involved in drug design will find the book invaluable.

  • International Review of Connective Tissue Research

    Volume 8
    • 1st Edition
    • David A. Hall + 1 more
    • English
    International Review of Connective Tissue Research, Volume 8, provides an overview of the state of knowledge in connective tissue research. The details of the structure of collagen and its biosynthesis are now well established, and attention has focused on the finer details of the biochemical mechanisms involved. The knowledge achieved so far is also being applied to studies of various physiological, developmental, and pathological mechanisms involving the connective tissues. These trends are reflected in the subject covered by this volume. The enzymes involved in the posttranslation modifications of collagen are being intensively investigated. The book deals with three of these: lysyl oxidase, the enzyme involved in the first stage of cross-link formation; and the two glycosyl transferases involved in the glycosylation of hydroxylysome residues. New collagen types are reviewed together with recent work on collagen messenger RNA. Both of these topics are important to the understanding of the control of collagen biosynthesis. The involvement of connective tissues in physiological and pathological processes is discussed in three areas. These are interaction of collagen with platelets in hemostasis; the biosynthesis of connective tissue components by smooth muscle cells; and biochemical research on the intervertebral disc, the disease of which is behind the majority of back pain problems.

  • Essays in Toxicology

    Volume 7
    • 1st Edition
    • Wayland J. Hayes
    • English
    Essays in Toxicology, Volume 7 presents essays on toxicology and related topics. The book presents essays on the effects of toxicants on reproductive performance; an overall view of carcinogenesis from an epidemiological viewpoint and the potentialities and limitations of the epidemiological method in cancer control; and the activity of cytochrome P450 and mixed-function oxidase in target and nontarget organisms. The text also includes essays on the toxicity of hexachlorophene and the use of hexachlorophene as an antibacterial agent; the methodology, dose measurement, and respiratory function assessment in respiratory toxicology; as well as behavioral toxicology, with focus on early warning and worker safety and health. Pharmacologists, biochemists, pathologists, neurophysiologists, epidemiologists, and toxicologists will find the book invaluable.

  • Agriculture, Growth and Redistribution of Income

    Policy Analysis with an Applied General Equilibrium Model in India
    • 1st Edition
    • Volume 190
    • N.S.S. Narayana + 2 more
    • J. Tinbergen
    • English
    This book presents an empirically estimated applied general equilibrium model for India and the analysis of a wide range of policy issues carried out using the model. The various chapters in the book deal with public distribution policies, foreign trade and aid policies, rural works programmes, terms of trade policies, fertilizer subsidy policies and irrigation development policies. These policies are analysed in terms of their immediate and medium term effects on production, consumption and prices of different commodities, on the growth of the economy as well as on the distribution of income among different groups in rural and urban areas and the incidence of poverty in the economy. Each chapter dealing with policy analysis describes the analytical issues involved, the historical context and experience of the policy concerned, results of the model scenarios and the policy insights that emerge.

  • Hormone Action in Plant Development — A Critical Appraisal

    • 1st Edition
    • G. V. Hoad + 2 more
    • English
    Hormone Action in Plant Development - A Critical Appraisal documents the proceedings of the Tenth Long Ashton Symposium, September 1986. The symposium was convened to assess the evidence for and against the view that plant hormones are endogenous regulators of plant development. The meeting also aimed to focus on and assess promising strategies for future research. The symposium opened with the Douglas Wills Lecture, given by Professor Carl Leopold. In many respects, progress in research on animal hormones seems greater than in the plant sciences and there may well be merit in following progress in animal hormone research as suggested by Professor Leopold. The symposium was comprised of four sessions. The introductory session considered the coordinating role of hormones in plant growth and development, and focused on hormone action at the molecular level, including their binding to receptors and their control of gene expression. The next two sessions embraced contributions on the experimental manipulation of development by genetic (notably by biochemical mutants), chemical (for example, with gibberellin/biosynth... inhibitors), and environmental (including drought stress) means. All these approaches consolidated the central importance of hormones in plant growth. In the final session, three speakers suggested some promising avenues for future research into the physiology, biochemistry, and molecular biology of plant hormones.

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