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Elsevier

Books in Life sciences

  • Developmental and Cellular Skeletal Biology

    • 1st Edition
    • Brian K. Hall
    • English
    Developmental and Cellular Skeletal Biology reviews the development, growth, and cell biology of the skeleton. The monograph provides a comprehensive overview of the aspects of skeletal biology, focusing mainly on the cellular level. It covers topics on the types of skeletal tissues, its evolution, and origin; location of the skeleton within the embryo; initiation of centers of skeletogenesis; and the initiation of skeletal growth. The book will be of great use to physiologists, cell biologists, hematologists, pathologists, orthopedic surgeons, and others whose professions are concerned with the study of the skeletal system.

  • The Constant Catastrophe

    Malnutrition, Famines and Drought
    • 1st Edition
    • Rolando V. Garcia + 1 more
    • English
    The Constant Catastrophe: Malnutrition, Famines, and Drought deals with the 1972 drought, and emphasizes the underlying social conditions that are related to its effects. The book examines the relationship of drought as a meteorological event and the famine that results as a social event. The effects of natural catastrophes become transformed by social structures and political processes in many countries of the world, more than which can be attributable to the physical cause itself. A striking parallelism that emerges in the study is that climatological analysis implies reference to large scale space and time processes. Famine also occurs as anomalies within large-scale processes in society—famine changes nutritional levels in communities. The text proposes a theoretical framework for a methodologically-ade... diagnostic tool that can be used in studying the "factual events" in previous cases of major disasters due to climactic factors. Case studies include those that happened in the Sahel, Ethiopia, India, China, the United Kingdom, and Brazil. Among several recommendations, one which the book proposes in the management of the effects of drought, is to adopt an approach similar to that of the Red Cross. The book is suitable for economists, environmentalists, ecologists, and policy makers involved in crisis management, food production, and rural development.

  • Plant Diseases

    Epidemics and Control
    • 1st Edition
    • J. E. Van Der Plank
    • English
    Plant Diseases: Epidemics and Control provides a description of the methods of epidemiological analysis based on infection rates and the relation between the amount of inoculum and the amount of disease it produces. The book shows how to study the increase of pathogen populations and the epidemiological strategy to be adopted to control the epidemic of plant diseases. The text covers the calculation of the logarithmic increase of disease; use of epidemiology in the study of control; forms of sanitation; the use of resistant plant varieties; and the design of field experiments. Plant pathologists and breeders, agriculturists, horticulturists, research workers, teachers, and students will find the text invaluable.

  • International Review of Connective Tissue Research

    Volume 7
    • 1st Edition
    • David A. Hall + 1 more
    • English
    International Review of Connective Tissue Research, Volume 7 focuses on the structural aspects of the connective tissues and their compounds. This book reviews the data concerning the primary structure of collagen and explores the physical features of elastin. Organized into six chapters, this volume begins with an overview of the amino acid sequence of collagen. This text then examines the relationship of the structure and function of elastic tissues and reviews the usefulness of immunological methods when applied to structural studies. Other chapters consider the substantial progress in the elucidation of the antigen determinants of the collagen molecule. This book discusses as well the immunological properties of collagen that may have considerable bearing on the causes of some connective tissue diseases. The final chapter deals with the extensive investigations into glycoproteins in various connective tissues of various species at various ages. This book is a valuable resource for biochemists and physicians.

  • Biological Response Mediators and Modulators

    John Jacob Abel Symposia on Drug Development
    • 1st Edition
    • J. Thomas August
    • English
    Biological Response Mediators and Modulators explains that the behavior of a cell depends upon the absorption of the ligand, the quantity of functional receptors existing for ligand recognition and binding, and the transduction of the signal through successive intercellular events. The book presents such model systems as the low-density lipoprotein (LDL) receptor, the epidermal growth factor receptor, and the insulin receptor. The LDL receptor is a model for a class of surface receptors that facilitate the cellular application of macromolecules through the process of receptor-mediated endocytosis. The book discusses the general characteristics of receptor-mediated endocytosis. Another topic of interest is the property of growth-related cell surface receptors. The section that follows describes the function of these receptors as tyrosine-specific protein kinases, which is related to the protein yields of some viral oncogenes. The amount of receptors in a cell depends upon the rates of synthesis and inactivation. The book will provide valuable insights for scientists, cytologists, students, and researchers in the field of chemistry.

  • The Life of Structures

    Physical Testing
    • 1st Edition
    • G.S.T Armer + 2 more
    • English
    The Life of Structures: Physical Testing covers the proceedings of a seminar of the same name. The said seminar is focused on the actions on structures and the performance of existing populations of structures; the properties and performance of building materials; and the internal and external environments of buildings. The book covers topics such as the methodology for the prediction of the life of existing structures; reliability of service-proven structural systems; and some effects of micro-environment on materials. Also covered are subjects such as the assessment of structures through field measured dynamic response; physical properties of structures investigated by dynamic methods; and the stiffness damage test. The text is recommended for engineers who would like to know more about the strength and lifespan of structures, as well as the effectivity of the materials involved in their construction.

  • Introduction to Animal Physiology and Physiological Genetics

    International Series of Monographs in Pure and Applied Biology
    • 1st Edition
    • E. M. Pantelouris
    • G. A. Kerkut
    • English
    Introduction to Animal Physiology and Physiological Genetics, deals with topics on physiological measurement, comparisons, and analysis of the role of genotypes. This book emphasizes two aspects — the changes of physiological patterns in the course of development and the wide variation that can be found within a species. The text discusses the response mechanisms of living organisms from nerve impulses, chemical sense, muscle reaction, and includes some studies made on brain function. The effects of nutrition and energy such as the intake of food, water, oxygen, and the calculation of basic metabolic rates are explained. The book then discusses the role of the internal environment and that of the interstitial body fluid in the higher animals. The discussion covers blood circulation, cardiac cycle, and a special section on the function of the heartbeat in the spider Limulus showing that stimulation of the abdominal ganglia increases the heartbeats. The text also considers significant concepts of physiological genetics, and then explains asexual and sexual reproduction, the sex hormones of invertebrates, and the use of stimulants for animal production. The physiological differences between species are examined, but more particularly on the reservoir of genetic diversity, where differences abound between families and offspring. One research made in molecular biology concludes that genes are responsible for regulating the amino acid sequence of proteins. Molecular biologists, general biologists, zoologists, and microbiologists will find the articles in this collection invaluable.

  • Neurotoxins

    • 1st Edition
    • Volume 8
    • P. Michael Conn
    • English
    The exquisite simplicity and potency of toxins have made them valuable probes of neural systems. This book presents a comprehensive compilation of techniques used for the preparation, handling, and, particularly, for the use of neurotoxins. Model systems are described in which these neurotoxins have been extremely valuable in developing an understanding of the cellular and molecular basis of secretion and electrophysiological events leading to altered cell function.

  • The Clinical Significance of the Essential Biological Metals

    • 1st Edition
    • I. J. T. Davies
    • English
    The Clinical Significance of the Essential Biological Metals covers the six trace minerals necessary for human survival,namely zinc, copper, manganese, molybdenum, chromium, and cobalt. This book contains seven chapters that specifically discuss the effects of these minerals for enzyme function, protein synthesis, and their nutritional significance in veterinary and agricultural practice. Some of the topics covered in the book are the importance of interactions between the essential biological metals; importance of fertilizers; analysis of water supply, soil mineral content, and cancer mortality; influence of drinking water on atherosclerosis; non-essential but biologically important metals; and absorption and availability of zinc. Other chapters deal with the factors influencing absorption of zinc, the effects of copper on zinc availability, and the form and absorption of copper in the diet. A chapter is devoted to the role of lymphatics in copper absorption. Another chapter focuses on the distribution, absorption, and transport of manganese in the blood. The book can provide useful information to doctors, biochemists, nutritionists, students, and researchers.

  • Tropical Plant Types

    The Commonwealth and International Library: Biology Division
    • 1st Edition
    • B. G. M. Jamieson + 1 more
    • G. L. Watt
    • English
    Tropical Plant Types is a textbook dealing with bacteria and flowering plants of the tropics. It can be used along with books in tropical biology. The book first examines the simpler plant types known as unicellular or those consisting of a thallus. These organisms are the algae, fungi, lichens, bacteria, and some viruses. The text then describes the Bryophyta, the Pteridophyta, and the Spermatophyta. Compared to the others, the Spermatophyta or seed plants grow in wider range of territories and are the dominant land flora. The book then discusses the morphology of the Spermatophyta and their successful characteristics of survival. The book also analyzes the different plant parts, such as the root, the stem, the leaf, and the flower. A couple of chapters discuss pollination, fertilization, and the dispersal of seeds and fruits. The book then gives examples of tropical flower types, with some details on their distribution and morphology. The text also discusses perennial flowering plants, vegetation types, and plant communities found in tropical rain forests, in monsoon forests, and in the drier regions of the earth. The selection can serve as a textbook for pupils nearing the completion of their secondary education, freshmen university students, and for those who need to meet the requirements of the Cambridge Overseas Advanced Level Biology Examination.

  • Thyroid Disease and Muscle Dysfunction

    • 1st Edition
    • Ian Ramsay
    • English
    Thyroid Disease and Muscle Dysfunction covers the pioneering work of the author in the study of muscle dysfunction in patients with thyrotoxicosis. His contributions on this subject represent real advances in the understanding of metabolic muscle disease. This book is written to clarify the association between abnormalities of skeletal muscle and derangement of thyroid function. This book is organized into five chapters that describe the muscular abnormalities in people with hypothyroidism, explain the concepts of thyrotoxic periodic paralysis and thyrotoxic myopathy, discuss the association between thyroid disease and myasthenia gravis, and describe the changes in thyroid functions associated with miscellaneous muscle disorders. This book will be of interest to persons dealing with studies on the relation between thyroid disease and muscle dysfunction.

  • Polysaccharides in Food

    • 1st Edition
    • J.M.V. Blanshard + 1 more
    • English
    Polysaccharides in Food is a collection of papers that discusses concepts and advancements related to polysaccharides found in food products. The book is divided into five parts; Part I deals with topics such as the polysaccharides of the plant cell during growth; polysaccharide structure in solutions and gels; and the solvent interactions and solution behavior of carbohydrates. Part II covers the relationship of polysaccharides and enzymes and includes topics such as the enzymic degradation of starches; the hemicellulase group of enzymes; and pectic enzymes. Part III discusses the structure and physiochemical aspects of starch, as well as its use in food. Part IV tackles polysaccharides in food product development, and Part V deals with kinds of polysaccharides and the legislations concerning them. Part VI covers the importance of polysaccharides as the population's energy source as well as its health benefits. The text is recommended for food technicians, nutritionists, and organic chemists who would like to know more about the importance of polysaccharides in food and its future.

  • Asthma

    Physiology, Immunopharmacology, and Treatment
    • 1st Edition
    • K. Frank Austen + 1 more
    • English
    Asthma: Physiology, Immunopharmacology, and Treatment is a collection of essays that discusses the clinical signs and symptoms of allergic bronchial asthma and the effects of a number of intricate sequences of biochemical reactions initiated by the combination of antigen and antibody. It presents such topic as the pathobiologic mechanisms of asthma. The book discusses the physiologic changes in the acute asthmatic attack. It focuses on the autonomic regulation of airway smooth muscle and the nervous regulation of respiration. Another topic of interest is the genetic aspects of asthma. The section that follows is a review of the biochemical, pharmacological, and immunological factors in the release of chemical mediators from human lung. The book also presents the characteristics of pharmacologic receptor systems and the role of parasympathetic nervous system in asthma. The text will provide valuable insights for physicians, scientists, students, and researchers in the field of human anatomy.

  • Hormones and Embryonic Development

    Advances in the Biosciences
    • 1st Edition
    • G. Raspé
    • English
    Advances in the Biosciences 13: Hormones and Embryonic Development investigates various aspects of hormones and embryonic development, including their physiological and pharmacological effects. More specifically, this volume considers which maternal hormones are essential for normal mammalian embryonic development, as well as the time course of the occurrence of endocrine systems during mammalian fetal development. In addition, it examines the role of maternal or fetal hormones in the induction and differentiation processes during embryonic or fetal development. Comprised of 13 chapters, this book begins with an analysis of the metabolic effects of insulin and glucagon in fetal and newborn rats, as well as their physiologic significance during the perinatal period in rat and other species. The next chapter deals with sexual differentiation in the rat fetus; how hormones regulate sexual development and disrupt sexual differentiation; the role of progesterone and estrone in pregnant rats fed a protein-free diet; and effects of brain implants of testosterone propionate in newborn hamsters on sexual differentiation. The link between diethylstilbestrol ingestion during pregnancy and development of clear-cell adenocarcinoma in the vagina and cervix of the female offspring is also examined. This monograph will be of interest to biologists, bioscientists, physiologists, and pharmacologists.

  • Pigment Cell Biology

    Proceedings of the Fourth Conference on the Biology of Normal and Atypical Pigment Cell Growth
    • 1st Edition
    • Myron Gordon
    • English
    Pigment Cell Biology provides information on the growth of the pigment cell throughout its life cycle. This book explains how the pigment cell synthesizes its melanin. Organized into 34 chapters, this book begins with an overview of the factors that involved in governing the unique color pattern formation for three species of salamander. This text then explores the cranial and the caudal sections of the medullary plate that contribute to the pigment development of the head and the tail of amphibians. Other chapters consider the difference in the pituitary output of black and white axolotls. This book discusses as well the slow progress in the definition of the roles of the pituitary hormones in melanogenesis. The final chapter deals with a group of pigments that are derived by oxidation from tryptophan. This book is a valuable resource for embryologists, geneticists, histologists, physiologists, cytochemists, and endocrinologists. Comparative pathologists, biophysicists, and biochemists will also find this book useful.

  • Topical Reviews in Neurosurgery

    Volume 1
    • 1st Edition
    • J. M. Rice Edwards
    • English
    Topical Reviews in Neurosurgery, Volume 1 focuses on neurosurgery, a medical specialty concerned with the prevention, diagnosis, treatment, and rehabilitation of disorders that affect any portion of the nervous system. This book discusses the advances in computed tomography, vascular surgery in neurological disorders, and carotid endarterectomy. The extracranial-intracr... anastomosis, etiology of chronic subdural hematoma, radical surgery in the treatment of craniopharyngiomas, and syringomyelia are also covered. Other topics include the sensory neural deafness; aneurysmal hemorrhage; detection of carotid stenosis; bypass procedures; and completed stroke in the carotid territory. This publication likewise considers the middle cerebral aneurysms; cell kinetics of glioma; and pathophysiology of enlargement of chronic subdural hematomas. This publication is a good source for neurosurgeons and medical students interested in neurosurgery.

  • International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, November 13 to 15, 1969

    Life Science Monographs
    • 1st Edition
    • G. Raspé + 1 more
    • English
    International Symposium on the Treatment of Carcinoma of the Prostate, Berlin, November 13 to 15, 1969 presents a resolution to the doubts and uncertainty in the treatment of carcinoma and formulate a new policy for handling. It discusses the basis of hormonal treatment of prostatic cancer. The focus of study is the pharmacological aspects of prostate cancer treatment. Some of the topics covered in the book are the metabolism of testosterone in the prostate, the use of stilbestrol diphosphate in treating prostate cancer, the pathology of prostate cancer, and the cardiovascular complications of the disease. The subjects on orchiectomy and adrenalectomy are covered. The modern radiotherapy is discussed. The text identifies the use of radioactive isotopes. An analysis of the irradiation of the hypophysis is presented. A chapter of the volume is devoted to the cytotoxic agents in prostate carcinoma treatment. Another section of the book focuses on application of cryo-therapy. The book will provide useful information to doctors, oncologists, radiologists, students and researchers.

  • The Physiology of Earthworms

    International Series of Monographs on Pure and Applied Biology: Zoology
    • 1st Edition
    • M. S. Laverack
    • G. A. Kerkut
    • English
    The Physiology of Earthworms focuses on the three species of earthworms — Liimbricus terrestris, Eisenta foetida, and Allolobophora longa. Other earthworms or oligochaetes such as the fresh-water species are briefly mentioned. The topics covered include the biochemical architecture; digestion and metabolism; calciferous glands; axial field; nitrogenous excretion; water relations; respiration; physiology of regeneration; neurosecretion; nervous system; and behavior of oligochaetes. This book is a good source of information for biology students and researchers conducting work on earthworms and its different species.

  • Government Regulations, Pheromone Analysis, Additional Pesticides

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 8
    • 1st Edition
    • Gunter Zweig + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume 8: Government Regulations, Pheromone Analysis, Additional Pesticides covers the pesticide law, pertaining to regulations for the registration of pesticides in the United States. The book discusses the analysis of naturally occurring chemicals that control the behavior of insects, as well as the methods for formulation and residue analyses for over twenty-five commercial pesticides, includes insecticides, fungicides, herbicides, growth regulators, and miscellaneous pesticides. Toxicologists and people involved in the study of agricultural chemicals will find the text invaluable.

  • Comparative Neurochemistry

    Proceedings of the Fifth International Neurochemical Symposium
    • 1st Edition
    • Derek Richter
    • English
    Comparative Neurochemistry, a collection of papers presented at the Fifth International Symposium of Comparative Neurochemistry, held at St. Wolfgang, Austria in 1962, deals with variations in neurochemical mechanisms in different animal species. The book integrates the data derived from comparative studies in different disciplines and assesses their significance in relation to the understanding of nervous mechanisms in animals, including human. The papers are grouped into sections, which cover general topics on functional organization in different species; lipids, proteins, and ribonucleic acid; amino acids in different species; energy metabolism and function; neurosecretory mechanisms; and comparative neuropharmacology. The text will be of interest to biologists, zoologists, pharmacologists, chemists, neurologists, and researchers in the pharmaceutical and chemical industries.

  • Toxicology and Experimental Models

    Proceedings of the 8th International Congress of Pharmacology, Tokyo, 1981
    • 1st Edition
    • H. Yoshida + 2 more
    • English
    Advances in Pharmacology and Therapeutics II, Volume 5: Toxicology and Experimental Models is the fifth of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into six parts, this book begins by elucidating the rational interpretation of species and strain differences in toxicity for the prediction of risk to man. Subsequent parts discuss the chemical interactions resulting in liver and kidney injury; the role of heme synthesis and degradation in predicting drug toxicity; and delayed toxic effects of pre- and perinatal drug exposure. Other chapters describe models of experimental peptic ulcers and therapeutic agents and models and quality control of laboratory animals.

  • Selected Water Problems in Islands and Coastal Areas

    With Special Regard to Desalination and Groundwater
    • 1st Edition
    • Sam Stuart
    • English
    Selected Water Problems in Islands and Coastal Areas serves as a guideline for implementing, at the policy and decision-making level, the rational and economic use of water resources. This book focuses on groundwater management and the possible utilization of desalination facilities, specifically in arid or semi-arid coastal areas. Organized into five parts encompassing 63 chapters, this book begins with an overview of the forecasts of water supply requirements. This text then explores the necessary regulations of both surface and groundwater in coastal areas and islands with limited water resources. Other chapters consider the curative measures in the case of recurring salination by using artificial or increased natural infiltration. This book discusses as well the techniques to be used for artificial infiltration into aquifers using deep wells to avoid clogging. The final chapter deals with the problems of communal installations, water supply, drainage and waste disposal. This book is a valuable resource for engineers.

  • Pharmacology of the Coronary Circulation

    Volume 10
    • 1st Edition
    • Natalia V. Kaverina
    • English
    Pharmacology of the Coronary Circulation focuses on the effects of pharmacological substances on the circulation of the heart, physiology of coronary circulation, effects of adrenomimetic, cholinergic, and ganglion-blocking agents, phenothiazine derivatives, analgesics, nitrites, and nitrates on cardiac vessels and results of clinical trials on Chloracizine. The publication first offers information on the physiology of the coronary circulation and the effects of pharmacological substances on the coronary circulation, including myotropic and neutropic substances and other substances. The book then examines the effects of adrenomimetic substances and cholinergic substances on the coronary circulation. The manuscript evaluates the effects of ganglion-blocking substances and analgesic substances on the coronary circulation. Topics include nicotine, etraethylammonium, hexamethonium, pentamine, and mecamine. The publication then takes a look at the effects of phenothiazine derivatives on the coronary circulation; importance of reflex reactions in connection with the development of acute coronary insufficiency; and effects of pharmacological substances on reflex reactions in the coronary vessels. The book is a dependable reference for readers interested in the pharmacology of the coronary circulation.

  • Adaptation to Environment

    Essays on the Physiology of Marine Animals
    • 1st Edition
    • R. C. Newell
    • English
    Adaptation to Environment: Essays on the Physiology of Marine Animals contains a series of essays that is intended as a review of the special adaptations of marine organisms to the particular environmental conditions they are likely to encounter in the natural habitat. This book emphasizes developments in physiology of marine animals and on approaches to the study of the adaptations of marine organisms. This compilation also interprets the term “Physiology” in its widest sense to include all aspects of the functioning of the organism from the behavior of animals to the mode of function of enzymes. For this reason, structural adaptations have been reviewed in detail only where their functional role is understood and where they constitute a specific adaptation to defined environmental conditions. This publication benefits students and individuals conducting research on the physiology of marine animals.

  • Unexpected Reactions to Modern Therapeutics

    Antibiotics
    • 1st Edition
    • Leo Schindel
    • English
    Unexpected Reactions to Modern Therapeutics: Antibiotics discusses the side-effects of antibiotics, specifically the allergic reactions of the skin and mucous membranes to penicillin. This book contains 12 chapters that address the specific organ reaction to penicillin and the complications of the gastro-intestinal tract after ingestion of chloramphenicol. Some of the topics covered in the book are the inhibition of the bone marrow function and blood changes after receiving doses of chloramphenicol; lesions of the skin and mucous membranes after applying tetracyclines; changes in the hemopoietic system, liver function, and structure after medication of oxy-tetracycline. Other chapters deal with the analysis of antibiotic resistant bacteria and the physiological adverse effects of neomycin. An analysis of the side-effects of erythromycin is provided. The concluding chapters describe the nephrotoxic effects of bacitracin and the epidermal effects of fumagillin. The book can provide useful information to doctors, pharmacologists, students, and researchers.

  • Recent Advances in Animal Nutrition – 1977

    Studies in the Agricultural and Food Sciences
    • 1st Edition
    • William Haresign + 1 more
    • English
    Recent Advances in Animal Nutrition-1977 presents papers that tackle the various areas of concerns in raising ruminants. The book contains a total of 11 studies that examine the factors affecting rumen fermentation. The text first covers EEC and feed compounding, and then proceeds to discussing the aspects of the biochemistry of rumen fermentation. Chapter 3 examines the influence of nitrogen and carbohydrate inputs on rumen fermentation. Chapter 4 talks about reducing the rate of ammonia release through alternative non-protein nitrogen sources. The fifth chapter describes the potential of protected proteins in ruminant nutrition. Next, the book discusses the manipulation of rumen fermentation. Chapter 7 covers the application of non-protein nitrogen, protected proteins, and rumen fermentation control. The next two chapters deal with broilers and turkeys. The eleventh chapter talks about predicting growth response in pigs, while the last chapter covers fish nutrition. The book will be most useful to both researchers and practitioners of animal related disciplines, such as agriculture and veterinary medicine.

  • Microwave Fixation of Labile Metabolites

    Proceedings of an Official Satellite Symposium of the 8th International Congress of Pharmacology Held in Tokyo, Japan, on 25 July 1981
    • 1st Edition
    • C. Leroy Blank + 2 more
    • English
    Microwave Fixation of Labile Metabolites documents the proceedings of an official Satellite Symposium of the 8th International Congress of Pharmacology held in Tokyo, Japan, on 25 July 1981. The Symposium was entitled ""Drug Effects on Rapidly Metabolized Compounds in the CNS: Rapid Tissue Fixation with Microwave Irradiation."" The volume begins with a discussion of the use of microwave irradiation to study the concentration and interrelationships of neurochemicals in the brain. This is followed by papers on the effects of immobilization on the increases in cerebellar cyclic GMP induced by cold exposure or apomorphine; importance of rapid enzymatic inactivation prior to the determination of endogenous levels of catecholamines; use of glycolic acid to study catecholamines in the brain following microwave irradiation. Also include are studies on methods for preventing the post mortem increase in γ-aminobutyric acid (GABA); the effect of microwave irradiation on catecholamine levels in the central nervous system; and effect of microwave irradiation in the brain histamine level of rats.

  • Biochemistry of Characterised Neurons

    • 1st Edition
    • Neville N. Osborne
    • English
    Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.

  • Neuropsychopharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
    • 1st Edition
    • C. Dumont
    • English
    Advances in Pharmacology and Therapeutics, Volume 5: Neuropsychopharmacol... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of neuropsychopharmacol... and cover topics ranging from anti-schizophrenic drugs to drug pathways in depression treatment. Pharmacological interferences with nonstriatal dopaminergic systems are also discussed. This volume is comprised of 21 chapters and opens by considering the nanomolar affinity of pre- and post-synaptic dopamine receptors for neuroleptics. The next section deals with drug pathways in the treatment of depression, with particular reference to the biochemical mechanisms of depressive states and the therapeutic effects of some antidepressants. The following chapters examine dopamine receptors in the nucleus accumbens; modulation of mesolimbic dopamine mechanisms via serotonin and GABA; how mesocortical dopaminergic neurons react to stress; and the behavioral consequences of the interaction between morphine, substance P, and nonstriatal dopamine neurons. This book will be of interest to practitioners in biosciences, pharmacology, physiology, psychology, neurology, and medicine.

  • Dictionary of Nutrition and Food Technology

    • 4th Edition
    • Arnold E. Bender
    • English
    Dictionary of Nutrition and Food Technology, Fourth Edition provides definitions of terms, abbreviations, and trade names related to nutrition and food technology. The coverage of the book includes words from various scientific disciplines, such as chemistry, biochemistry, microbiology, and engineering. The text will be of great use to specialists from different fields who seek to understand the technical terms used in the food fields.

  • Human Cytogenetics

    Clinical Cytogenetics
    • 1st Edition
    • John L. Hamerton
    • English
    Human Cytogenetics: Clinical Cytogenetics, Volume II presents the general theoretical principles and clinical aspects of cytogenetics, a branch of genetics that deals specifically with the study of the chromosomes. The volume focuses on the clinical cytogenetics of human. It discusses the sex chromosomes and their abnormalities and the abnormalities of sexual development and differentiation; mechanism of sex determination in mammals; major autosomal abnormalities found in human populations; and chromosome abnormalities in relation to human pregnancy wastage and chromosome changes in neoplasia. The book will be a great reference book for geneticists, cytogeneticists, pathologists, clinicians, and medical students.

  • Crohn's Disease

    • 1st Edition
    • James Kyle
    • English
    Crohn's Disease provides the incidence, effects, and the empirical forms of treatment of Crohn's Disease. Chapters in the book provide insights into the history of Crohn's disease, epidemiology, aetiology, pathology, signs and symptoms, complications, diagnosis, and medical treatment. Physiologists, physicians, aetiologists, epidemiologists, and medical researchers will find the book invaluable.

  • Comprehensive Insect Physiology, Volume 3

    Integument, Respiration and Circulation
    • 1st Edition
    • G. A. Kerkut
    • English
    This volume is primarily devoted to the analysis of the integument (epidermis, cuticle), the fat body, the connective tissues, the circulatory and respiratory systems. It discusses the organization and functioning of the insect systems implicated in growth, intermediary metabolism, homeostasis and defence mechanisms. Much of the volume is devoted to anatomical and structural developments, which appear as introductions to corresponding biochemical and physiological aspects. Many diagrams, drawings and photographs accompany the text throughout. Altogether, this volume presents a clear and up-to-date account of the most recent and important discoveries in the fields and shows the extent of progress which is expected in the near future.

  • Bone Mineral Metabolism in Cancer

    Recent Results in Cancer Research
    • 1st Edition
    • Janusz Szymendera
    • V. G. Allfrey + 2 more
    • English
    Recent Results in Cancer Research: Bone Mineral Metabolism in Cancer presents the clinical approach to bone tissue metabolism, which depends on studying the plasma state, renal handling, kinetics, and balance of calcium and inorganic phosphate. This book discusses the problems of bone mineral metabolism in patients with cancer. Organized into five chapters, this book begins with an overview of the two major phases of bone mineral, namely, amorphous calcium phosphate and crystalline bone apatite. This text then examines the plasma state and renal handling of calcium and inorganic phosphate under controlled metabolic conditions. Other chapters consider the variability of each parameter in the majority of patients without bone secondaries. This book discusses as well the normal remodeling of bone in fertile-age women. The final chapter deals with the plasma state, renal handling, and kinetics of calcium and phosphate in plasmacytoma patients. This book is a valuable resource for oncologists.

  • Diseases of the Ear, Nose, and Throat

    • 2nd Edition
    • Douglas G. Carruthers
    • English
    Diseases of the Ear, Nose, and Throat, Second Edition covers more updated topics on the diseases of the ear, nose, and throat, including the methods of examination and treatment of these diseases, compared to those presented in the previous edition. This book first discusses the clinical examination of the regions of the ear, nose, and throat. Each of the subsequent chapters discusses a particular organ and its diseases. Some of the organs looked into are the larynx and the esophagus. This text will be invaluable to students and specialists in the field of biology, physiology, medicine, and related disciplines.

  • Cooperative Phenomena in Biology

    • 1st Edition
    • George Karreman
    • English
    Cooperative Phenomena in Biology deals with cooperation in biology and covers topics such as cooperative specific adsorption; the kinetics of oxygen binding to hemoglobin; allosteric control of cooperative adsorption and conformation changes; and cooperativity in biological surfaces responding to topical treatment. The use of Monte Carlo methods to investigate the behavior of cooperative Ising models is also described. This book is comprised of five chapters and opens with a discussion on the phenomenon of cooperative specific adsorption and its importance for the understanding of fundamental biological phenomena. The derivation of the cooperative specific adsorption isotherm both stochastically and on the basis of statistical mechanics is explained. The next chapter reviews the theory of the allosteric control of cooperative adsorption and conformation changes and outlines a molecular model for physiological activities according to the association-inductio... hypothesis. The reader is also introduced to a kinetic equation for hemoglobin oxygenation based on the infinite chain; the use of bioelectrometric methods to study solute interactions with biocolloidal surfaces responding to topical treatment; and the use of Monte Carlo computations to determine the behavior of cooperative Ising models. This monograph is intended for biologists, physicists, chemists, and mathematicians.

  • Aspirin and the Salicylates

    • 1st Edition
    • K. D. Rainsford
    • English
    Aspirin and the Salicylates focuses principally on aspirin. Topics ranging from analytical chemistry and pediatric medicine, taxonomy and cartels, enzymology and toxicity, to renal functions and rheumatology are also included in this compilation. This book emphasizes that salicylates are polycompetent drugs that influence a large number and variety of biological processes. Their multifactorial actions, in relation to the known therapeutic and toxic effects are clearly described. This text likewise provides a refreshing multidisciplinary approach to aspirins that cover the whole extent from chemical to clinical aspects. This publication is a good reference for clinicians, pharmacists, and students intending to acquire general knowledge of the aspirin and salicylates.

  • Handbook of Small Animal Oral Emergencies

    • 1st Edition
    • Cecilia Gorrel + 2 more
    • A. T. B. Edney
    • English
    Handbook of Small Animal Oral Emergencies provides a guideline in handling common oral problems among small animals. The book presents both written steps and illustrations of the procedures covered. The first chapter provides an introductory discussion on the coverage of the text. Chapter 2 discusses dental radiography and radiology. Chapter 3 tackles infective conditions, while Chapter 4 deals with soft tissue trauma. Chapter 5 covers traumatic tooth injuries, while Chapter 6 discusses jaw fractures. Chapter 7 tackles malocclusions. The book will be of great use to practitioners of veterinary medicine, especially those who specializes in veterinary dentistry.

  • Light and Plant Development

    • 1st Edition
    • H. Smith
    • English
    Light and Plant Development presents the Proceedings of the 22nd University of Nottingham Easter School in Agricultural Science. It discusses the spectral sensitivity of inhibition of flowering by light. It addresses the action spectrum for leaf enlargement and stem growth inhibition. Some of the topics covered in the book are the nature of the blue light photoreceptor in higher plants and fungi; re-examination of photochemical properties and absorption characteristics of phytochrome using high-molecular-weigh... preparations; and intermediates in the photoconversion of phytochrome. The high irradiance reaction is fully covered. The physiological evidence and localised responses, intracellular localisation and action of phytochrome are discussed in detail. The text describes in depth the immunological visualisation of phytochrome. The fractionation procedures and terminology are presented completely. A chapter is devoted to the photocontrol of enzyme levels. Another section focuses on the ribosomal RNA synthesis in developing leaves. The book can provide useful information to botanists, chemists, students, and researchers.

  • Cellular and Molecular Mechanisms of Inflammation

    Signal Transduction in Inflammatory Cells, Part A
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Cellular and Molecular Mechanisms of Inflammation: Signal Transduction in Inflammatory Cells, Part A is a collection of papers that discusses the mechanisms of the transduction of signals linking stimulated receptors and cellular function. This book describes the pathways of signal transduction involved in stimulating functions of inflammatory cells connected with host defense and development of inflammatory injury. One paper notes the potential of using fluorescence methodology in analyzing ligand-receptor interactions in living systems during the natural abundance of cell surface receptors. Another paper discusses the structure and function of GTP-binding proteins in neutrophil signal transduction, particularly the role of oligomeric G proteins in signal transduction. One concern in signal transduction research is the physiological significance of the presence of multiple forms of proteins that can have identical functions. One paper reviews phosphatidylcholine breakdown and hormone action in the rat liver, focusing on G proteins and on inositol phospholipid breakdown. This book also discusses calcium translocation in signal transduction, as well as, a novel signal transduction pathway involving phosphatidylinositol 3-kinase. This book can prove beneficial for biochemists, micro-biologists, cellular researchers, and academicians involved in the study of cellular biology, physiology or oncology.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 8
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume VIII covers a critical review and new extensions of quantitative methods in drug design, the design of particular types of agents, such as synthetic sweeteners, and selective ion binding compounds. The book discusses the advances in the methodology of quantitative drug design; the application of pattern recognition to drug design; and the design of controlled drug delivery systems. The text also describes the use of receptor binding as a tool in the development of new bioactive steroids; the design of synthetic sweeteners; and the prospective assessment of environmental effects of chemicals. The design of selective ion binding macrocyclic compounds and their biological applications are also encompassed. Chemists, pharmacologists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

  • Advances in Gene Technology: Molecular Genetics of Plants and Animals

    • 1st Edition
    • Kathleen Downey + 2 more
    • English
    Advances in Gene Technology: Molecular Genetics of Plants and Animals contains the proceedings of the Miami Winter Symposium held in January 1983 in Miami, Florida. The papers explore advances in the molecular genetics of plants and animals and cover a wide range of topics such as genetic manipulation of plants; plant cell cultures, regeneration, and somatic cell fusion; and nitrogen fixation. Practical applications of gene technology with plants are also discussed. Comprised of 84 chapters, this volume begins with an overview of how plants manufacture from carbon dioxide and water all of their substances, paying particular attention to the path of carbon in photosynthesis. The organization of the plant genome is then considered, along with techniques for cell culture, regeneration, and somatic cell fusion; vector systems; and nitrogen fixation. Some chapters focus on gene transfer by protoplast fusion; somatic cell genetic systems in corn; regulation of transcription of the nitrogen fixation operons; and leghemoglobin and nodulin genes of soybean. The final section is devoted to practical applications of gene technology to plants and to technology frontiers in animal biology, in particular embryonic development and vaccines and diagnostic methods for animal diseases. This book should be of value to molecular geneticists.

  • Pharmacology in Clinical Practice

    • 1st Edition
    • Richard Lancaster
    • English
    Pharmacology in Clinical Practice describes basic pharmacology, clinical pharmacology, including the pharmacology of important drug groups. The author reviews the general principles of clinical pharmacology including drug actions, absorption, disposition, and excretion. Most drugs are xenobiotics—compound... foreign and harmful to human living tissues. Drugs should be properly metabolized and converted to nontoxic substance before being excreted either through spontaneous changes not mediated by enzymes or through transformation by enzyme systems. The author also discusses pharmacokinetics, including drug plasma concentration, absorption, first-pass metabolism, distribution and elimination. The author addresses pharmacogenetics that deal with possible different responses to drug intake due to factors such as age, sex, liver or renal disease, smoking, diet. The book tackles other drugs, their uses, and characteristics such as antibacterial agents, obesity drug, cytotoxic drugs or those used in chemotherapy medicine. The author explains the diagnosis of drug ingestion, clinical signs of overdose, clinical course, and prophylactic measures for users to avoid drug overdose or self-poisoning. This book is intended for medical undergraduates, pharmaceutical technicians, pharmacists, students or professors in pharmacology or general medicine.

  • International Review of Forestry Research

    Volume 3
    • 1st Edition
    • John A. Romberger + 1 more
    • English
    International Review of Forestry Research, Volume 3 reviews some areas of forest science that are of growing importance. The book discusses the advances in poplar breeding; the economics of yield planning; and the mycorrhizal inoculation in afforestation. The text also describes the heart rots in living trees; and the biochemical approaches to forest genetics. People involved in forest research, silviculture, and populiculture will find the book invaluable.

  • Infections of the Nervous System

    Butterworths International Medical Reviews
    • 1st Edition
    • Peter G. E. Kennedy + 1 more
    • English
    Infections of the Nervous System aims to continue the legacy of its predecessor, Modern Trends in Neurology. Its goal is to produce annually a monograph on a topic in clinical neurology in which progress through research has brought about new concepts of patient management. This book is organized into 13 chapters. It highlights the areas or subjects in which significant advances have been made which also have relevance to the treatment of patients. It covers a number of important aspects of different infectious diseases of the nervous system including acute bacterial meningitis, tuberculosis of the nervous system, spirochaetal infections of the nervous system, and fungal diseases of the central nervous system. This book is intended for use by physicians who deal with the problems of neurological disorder on a daily basis, whether they are neurologists, neurologists in training, or those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • Drugs in Psychiatric Practice

    • 1st Edition
    • Sam Stuart
    • English
    Drugs in Psychiatric Practice present a comprehensive examination of the drug treatment in psychiatry. It discusses certain ways in which drugs behaved. It addresses the advances in pharmacology and the basis of prescription. Some of the topics covered in the book are the classification of psychotropic drugs; basic principles of pharmacokinetics and drug metabolism; anti-schizophrenic drugs; evaluation of psychotropic drugs; unconventional chemotherapy; anti-parkinsonian and anti-dyskinetic drugs; introduction of amitriptyline; and tricyclic antidepressants. The role of tricyclic drugs in the treatment of enuresis and the drug treatment of organic brain syndrome are fully covered. An in-depth account of the monoamine oxidase inhibitors and amine precursors are provided. The tolerance and pharmacological dependence on alcohol are completely presented. A chapter is devoted to the factors involve in ethanol metabolism. Another section focuses on the unwanted effects of psychotropic drugs. The book can provide useful information to doctors, pharmacists, psychologists, students, and researchers.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 4
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume IV covers the pharmaceutical phase of drug action, with emphasis on those aspects that are of importance in the design of optimally effective drug products. The book discusses biopharmaceutics as a basis for the design of drug products; the types and pharmacokinetics of peroral prolonged action dosage forms and parenteral prolonged action forms; and the design of topical drug products. The text also describes physical-chemical parameters which affect the bioavailability of topical drug products; the design of sunscreen preparations; as well as the clinical application of litholytic agents, which are preventive and curative drugs for nephrolithiasis. The design of biologically active nucleosides and of insecticidal chlorohydrocarbon derivatives is also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

  • Lipid Metabolism in Signaling Systems

    • 1st Edition
    • Volume 18
    • P. Michael Conn + 1 more
    • English
    Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume.

  • Infectious Diseases

    • 2nd Edition
    • A. Melvin Ramsay + 1 more
    • English
    Infectious Diseases, Second Edition furnishes the basic facts regarding the common infections encountered in the British Isles. The infectious diseases covered in this edition include varicella and herpes zoster, smallpox, tetanus, measles, mumps, influenza, and acute respiratory disease. The poliomyelitis, Stevens-Johnson syndrome, malaria, tuberculosis, cytomegalic inclusion disease, and rabies are also discussed. This book likewise deliberates the host-parasite relationship, control of infection in hospitals, sterilization and disinfection, pyrexia of undetermined origin (PUO), and public health law. This publication is valuable not only to clinicians but also to epidemiologists, microbiologists and community physicians whose work is connected with the many problems in the field of acute medicine.

  • Epidemiology in Country Practice

    • 1st Edition
    • William Norman Pickles
    • English
    Epidemiology in Country Practice presents the development of the catarrhal jaundice and myalgia. It discusses the epidemiological and clinical observations of country doctors. It addresses the conditions of life of a country doctor. Some of the topics covered in the book are the appeal to improved medical research; methods of communicating medical research; techniques in acquisition of clinical data; types of diseases of the people living in the country; description of influenza, measles, scarlet fever, whooping-cough, and mumps; and diagnosis and behavior of chicken-pox and shingles. The description of sonne dysentery is fully covered. An in-depth account of the diagnosis, symptoms, and treatment of undulant fever are provided. The characteristic mononucleosis of glandular fever is completely presented. A chapter is devoted to the classification and description of different skin conditions. Another section is focus on the diagnosis of malignant disease. The book can provide useful information to doctors, students, and researchers.

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