Muscle and Nonmuscle Motility

Contents

Contributors

Preface

Contents of Volume 2


1. Molecular Basis of Contraction in Cross-Striated Muscles and Relevance to Motile Mechanisms in Other Cells

I. Introduction

II. Structure of Muscle Fibers

III. Protein Components of the Filaments

IV. Changes in the Band Pattern of Muscle during Contraction and Stretch

V. Molecular Structure of the Filaments

VI. Molecular Changes during Contraction and in Rigor

VII. Some Biochemical and Physiological Implications of the Structural Results

VIII. Structural Details of the Cross-Bridge Mechanism

IX. Outstanding Problems and Future Work

References


2. Macromolecular Assembly of Myosin

I. Introduction

II. Assembly of Myosin Filaments

III. Assembly of Copolymers of Different Myosins (Hybridization)

References


3. Macromolecular Assembly of Actin

I. Introduction

II. G-F Transformation of Actin

III. Structure of F-Actin

IV. Conformation and Interaction of Actin Monomer

V. Interaction of F-Actin with Regulatory Proteins and Myosin

VI. Actin and Motility

VII. Concluding Remarks

References


4. Regulation of Contractility

I. Introduction

II. One Aspect of the Troponin Mechanism: The Role of Troponin T

III. General Aspects of the Regulatory Mechanism in Vertebrate Smooth Muscle

IV. Characteristics of Aorta Leiotonin

V. Troponin in Ascidian Smooth Muscle

VI. A Regulatory Factor in Slime Mold

VII. Concluding Remarks

References


5. The Regulation of Cytoplasmic Ca2+ Concentration in Muscle and Nonmuscle Cells

I. Introduction

II. The Sarcoplasmic Reticulum of Skeletal Muscle

III. The Transport of Ca2+ by Cardiac Sarcoplasmic Reticulum

IV. The Ca2+ Transport Activities of Cardiac Sarcolemma

V. Smooth Muscle

VI. The Regulation of Cytoplasmic Ca2+ Concentration in Nonmuscle Cells

References

Index