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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

    • Side Reactions in Peptide Synthesis

      • 1st Edition
      • September 1, 2015
      • Yi Yang
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 0 0 9 9
      • eBook
        9 7 8 0 1 2 8 0 1 1 8 1 2
      Side Reactions in Peptide Synthesis, based on the author’s academic and industrial experience, and backed by a thorough review of the current literature, provides analysis of, and proposes solutions to, the most frequently encountered side reactions during peptide and peptidomimetic synthesis. This valuable handbook is ideal for research and process chemists working with peptide synthesis in diverse settings across academic, biotech, and pharmaceutical research and development. While peptide chemistry is increasingly prevalent, common side reactions and their causes are often poorly understood or anticipated, causing unnecessary waste of materials and delay. Each chapter discusses common side reactions through detailed chemical equations, proposed mechanisms (if any), theoretical background, and finally, a variety of possible solutions to avoid or alleviate the specified side reaction.
    • Virtual Synthesis of Nanosystems by Design

      • 1st Edition
      • February 17, 2015
      • Liudmila Pozhar
      • English
      • Hardback
        9 7 8 0 1 2 3 9 6 9 8 4 2
      • eBook
        9 7 8 0 1 2 3 9 7 2 8 9 7
      This is the only book on a novel fundamental method that uses quantum many body theoretical approach to synthesis of nanomaterials by design. This approach allows the first-principle prediction of transport properties of strongly spatially non-uniform systems, such as small QDs and molecules, where currently used DFT-based methods either fail, or have to use empirical parameters. The book discusses modified algorithms that allow mimicking experimental synthesis of novel nanomaterials---to compare the results with the theoretical predictions--and provides already developed electronic templates of sub-nanoscale systems and molecules that can be used as components of larger materials/fluidic systems.
    • Essential Chemistry for Formulators of Semisolid and Liquid Dosages

      • 1st Edition
      • October 15, 2015
      • Vitthal S. Kulkarni + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 0 2 4 2
      • eBook
        9 7 8 0 1 2 8 0 1 0 7 2 3
      A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosit... microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.
    • Room Temperature Organic Synthesis

      • 1st Edition
      • March 18, 2015
      • Goutam Brahmachari
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 0 2 5 9
      • eBook
        9 7 8 0 1 2 8 0 1 1 3 8 6
      Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry.
    • The Practice of Medicinal Chemistry

      • 4th Edition
      • July 1, 2015
      • Camille Georges Wermuth + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 4 1 7 2 0 5 0
      • eBook
        9 7 8 0 1 2 4 1 7 2 1 3 5
      The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.
    • Combustion Calorimetry

      • 1st Edition
      • December 4, 2015
      • Stig Sunner + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 8 6 6 6
      • eBook
        9 7 8 1 4 8 3 1 5 1 0 8 3
      Combustion Calorimetry deals with expertise knowledge concerning the calorimetry of combustion reactions of an element or compound. After defining the use of units and physical constants, the book discusses the basic principles of combustion calorimetry and the various instruments and calorimeters used in the experiments to measure operations concerning temperatures and its time variations. One paper discusses the theory and design criteria of combustion calorimeter calibration. Another paper discusses the results obtained from a combustion calorimeter after it has measured the energy or enthalpy of combustion of an element or compound. The book then presents the need to define accurately the exact process in which a measured energy or enthalpy change is acknowledged. One paper then presents how to find an assessment of uncertainty for any experimentally determined value through analysis of random errors and the propagation of errors. Several papers discuss the combustion calorimetry of metals, of organometallic compounds, and of fluorine. One paper presents the technological applications of heat reaction especially in the design of a chemical production plant where a reactor volume should desirably be least expensive. The book then discusses the trends in combustion calorimetry such as the prevalence of a miniaturized bomb combustion calorimetry. This volume will be beneficial to researches, technicians, and scientists in the field of catalysis, biochemistry, synthetic chemistry, and medicine.
    • Practical NMR Spectroscopy Laboratory Guide: Using Bruker Spectrometers

      • 1st Edition
      • October 27, 2015
      • John S. Harwood + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 0 6 8 9 4
      • eBook
        9 7 8 0 1 2 8 0 0 7 1 9 8
      Practical NMR Spectroscopy Laboratory Guide is designed to provide non-expert NMR users, typically graduate students in chemistry, an introduction to various facets of practical solution-state NMR spectroscopy. Each chapter offers a series of hands-on exercises, introducing various NMR concepts and experiments and guiding the reader in running these experiments using an NMR spectrometer. The book is written for use with a Bruker NMR spectrometer running TopSpin software versions 1 or 2. This practical resource functions both as a text for instructors of a practical NMR course and also as a reference for spectrometer administrators or NMR facility directors when doing user training. This guide serves as serve as excellent, practical resource on its own or as a companion book to Timothy Claridge’s High-Resolution NMR Techniques in Organic Chemistry, 2nd Edition (Elsevier, 2009).
    • Absorption Spectra and Chemical Bonding in Complexes

      • 1st Edition
      • August 11, 2015
      • C. K. Jørgensen
      • English
      • Paperback
        9 7 8 1 4 8 3 1 6 8 8 4 5
      • eBook
        9 7 8 1 4 8 3 1 8 4 6 5 4
      Absorption Spectra and Chemical Bonding in Complexes focuses on chemical bonding in transition group complexes and molecules, including molecular orbitals, absorption bands, and energy levels. The book first outlines the history of chemical bonding, giving emphasis to different theories that paved the way for further studies in this field. The text then examines the energy levels of a configuration and molecular orbitals and microsymmetry. The publication takes a look at the interelectronic repulsion in M.O. configurations, the characteristics of absorption bands, and spectrochemical series. Electron transfer spectra, energy levels in complexes with almost spherical symmetry, molecular orbitals lacking spherical symmetry, and chemical bonding are also discussed. The book examines the determination of complex species in solution and their formation constants; survey of the chemistry of heavy, metallic elements; and tables of absorption spectra. The manuscript is a dependable source of data for physicists and group theorists interested in absorption spectra and chemical bonding.
    • The Encyclopedia of Mass Spectrometry

      • 1st Edition
      • December 4, 2015
      • English
      • Hardback
        9 7 8 0 0 8 0 4 3 8 4 8 1
      • eBook
        9 7 8 0 0 8 0 9 1 3 2 5 4
      Volume 9: Historical Perspectives, Part A: The Development of Mass Spectrometry of The Encyclopedia of Mass Spectrometry describes and analyzes the development of many aspects of Mass Spectrometry. Beginning with the earliest types of Mass Analyzers, Historical Perspectives explores the development of many different forms of analytical processes and methods. The work follows various instruments and interfaces, to the current state of detectors and computerization. It traces the use of Mass Spectrometry across many different disciplines, including Organic Chemistry, Biochemistry, and Proteomics; Environmental Mass Spectrometry; Forensic Science; Imaging; Medical Monitoring and Diagnosis; Earth and Planetary Sciences; and Nuclear Science.Finally, the book covers the history of manufacturers and societies as well as the professionals who form the Mass Spectrometry community. Also available: Volume 9: Historical Perspectives, Part B: Notable People in Mass Spectrometry briefly reviews the lives and works of many of the major people who carried out this development.
    • Drug-Like Properties

      • 2nd Edition
      • December 17, 2015
      • Li Di + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 0 7 6 1
      • eBook
        9 7 8 0 1 2 8 0 1 3 2 2 9
      Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Review chapters provide context and underscore the importance of key concepts such as pharmacokinetics, toxicity, the blood-brain barrier, diagnosing drug limitations, prodrugs, and formulation. Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization.