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Elsevier

Books in Life sciences

  • Neural Networks Modeling and Control

    Applications for Unknown Nonlinear Delayed Systems in Discrete Time
    • 1st Edition
    • Jorge D. Rios + 3 more
    • English
    Neural Networks Modelling and Control: Applications for Unknown Nonlinear Delayed Systems in Discrete Time focuses on modeling and control of discrete-time unknown nonlinear delayed systems under uncertainties based on Artificial Neural Networks. First, a Recurrent High Order Neural Network (RHONN) is used to identify discrete-time unknown nonlinear delayed systems under uncertainties, then a RHONN is used to design neural observers for the same class of systems. Therefore, both neural models are used to synthesize controllers for trajectory tracking based on two methodologies: sliding mode control and Inverse Optimal Neural Control. As well as considering the different neural control models and complications that are associated with them, this book also analyzes potential applications, prototypes and future trends.

  • Neurological Modulation of Sleep

    Mechanisms and Function of Sleep Health
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for neurological modulation of sleep via diet. This book expands the notion of diet and adds an element of physical activity and exercise as well as a chapter on caffeine and its effects on sleep. With 30+ international contributors, this book aims to provide readers with a unique global perspective on the role these factors plays in sleep architecture and its regulation by circadian biology and neurology. Sleep disorders have become an increasing problem plaguing more than 70 million Americans according to the American Sleep Association. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes.

  • Tumor Immunology and Immunotherapy – Cellular Methods Part A

    • 1st Edition
    • Volume 631
    • English
    Tumor Immunology and Immunotherapy – Cellular Methods Part A, Volume 631, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters include Detection of intracellular cytokine production by T cells with flow cytometry, High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers, In vitro assays for effector T cell functions and activity of immunostimulatory antibodies, Ex vivo energetic profiling of tumor cells and T cells from mouse models and human samples, A cytofluorimetric assay to evaluate T cell polyfunctionality, and much more.

  • Data Democracy

    At the Nexus of Artificial Intelligence, Software Development, and Knowledge Engineering
    • 1st Edition
    • Feras A. Batarseh + 1 more
    • English
    Data Democracy: At the Nexus of Artificial Intelligence, Software Development, and Knowledge Engineering provides a manifesto to data democracy. After reading the chapters of this book, you are informed and suitably warned! You are already part of the data republic, and you (and all of us) need to ensure that our data fall in the right hands. Everything you click, buy, swipe, try, sell, drive, or fly is a data point. But who owns the data? At this point, not you! You do not even have access to most of it. The next best empire of our planet is one who owns and controls the world’s best dataset. If you consume or create data, if you are a citizen of the data republic (willingly or grudgingly), and if you are interested in making a decision or finding the truth through data-driven analysis, this book is for you. A group of experts, academics, data science researchers, and industry practitioners gathered to write this manifesto about data democracy.

  • The Heparins

    Basic and Clinical Aspects
    • 1st Edition
    • David Green
    • English
    The Heparins: Properties and Clinical Applications brings the latest information on heparin, one of the world's most widely used drugs. The book describes the fascinating history of the discovery of this biological agent, how it was isolated and characterized, and its use for the treatment of thrombotic disorders. The structures of various heparins are illustrated, with their function as anticoagulants delineated. This comprehensive resource arms researchers and clinicians with a concise and practical source that will assist in biomedical research, medical practice, and in improving patient outcomes.

  • Protein Misfolding

    • 1st Edition
    • Volume 118
    • Rossen Donev
    • English
    Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more.

  • Latex, Laticifers and Their Molecular Components: From Functions to Possible Applications

    • 1st Edition
    • Volume 93
    • English
    Latex, Laticifers And Their Products, Volume 93 in the Advances in Botanical Research series, highlights new advances in the growing field of the latex of different plant species and a diversity of molecules produced by the plants within laticifers. The new volume presents timely chapters on the latest developments in Plant latex and latex-borne defense, Physiology and structure of laticifers, Low-molecular compounds of latex-bearing plants/Latex-based defense strategies against pests, Plant latex proteins and their functions, Latex and Laticifers as a Source of Useful Bioactive Compounds. Pharmacologically active compounds from latex of medicinal plants. Euphorbia latex biochemistry/ proteins, and more.

  • Agricultural Internet of Things and Decision Support for Precision Smart Farming

    • 1st Edition
    • Annamaria Castrignanò + 5 more
    • English
    Agricultural Internet of Things and Decision Support for Smart Farming reveals how a set of key enabling technologies (KET) related to agronomic management, remote and proximal sensing, data mining, decision-making and automation can be efficiently integrated in one system. Chapters cover how KETs enable real-time monitoring of soil conditions, determine real-time, site-specific requirements of crop systems, help develop a decision support system (DSS) aimed at maximizing the efficient use of resources, and provide planning for agronomic inputs differentiated in time and space. This book is ideal for researchers, academics, post-graduate students and practitioners who want to embrace new agricultural technologies.

  • Breakfast Cereals and How They Are Made

    Raw Materials, Processing, and Production
    • 3rd Edition
    • Alicia A. Perdon + 2 more
    • English
    Breakfast Cereals and How They Are Made: Raw Materials, Processing, and Production, Third Edition, covers the transformation of a cereal grain across the supply chain with oversight of the entire lifecycle – from ingredient, to finished product. The book provides essential Information for food product developers on the effect of ingredients and process conditions on breakfast cereal quality. All aspects of the processing of cereals grains into finished products is covered, from batching and cooking, toasting and tempering, coating, the inclusion of additional ingredients, and packaging information. In addition, the book covers the chemistry and economics of cereal crops. Essential reading for all product developers working in the cereal industry, this book will also be of interest to academic researchers and postgraduate students in both cereal science and food processing.

  • Sea Urchins

    Biology and Ecology
    • 4th Edition
    • Volume 43
    • John M. Lawrence
    • English
    Sea Urchins: Biology and Ecology, Fourth Edition, Volume 43 expands its coverage to include the entire class of Echinoidea, making this new edition an authoritative reference of the entire class of species. This is a valuable resource that will help readers gain a deep understanding of the basic characteristics of sea urchins, the basis of the great variation that exists in sea urchins, and how sea urchins are important components of marine ecosystems. Updated coverage includes sections on reproduction, metabolism, endocrinology, larval ecology, growth, digestion, carotenoids and disease.

  • Epidemiology of Thyroid Disorders

    • 1st Edition
    • Jahangir Moini + 2 more
    • English
    Epidemiology of Thyroid Disorders provides comprehensive, clinical knowledge to professionals dealing with thyroid disorders. The book focuses on the pathophysiology of thyroid disorders, the prevalence and incidence of various diseases, and their prevention. This focused analysis on thyroid disorders raises awareness of this global problem that, once diagnosed or misdiagnosed, can sometimes lead to over-treatment and cardiovascular complications, especially in the elderly. This succinct, targeted reference gives the reader excellent information on the epidemiology of global thyroid disorders, as well as up-to-date treatment data and a special focus on prevention.

  • Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease

    • 1st Edition
    • Shyamasree Ghosh
    • English
    Sialic Acids and Sialoglycoconjugates in the Biology of Life, Health and Disease enables the reader to understand the role of sialylation as a post translational modification. The book provides insights on the latest knowledge in the field of sialoglycobiology. Sialic acids as terminal residues of oligosaccharide chains play crucial roles in several cellular recognition events. Synthesized post translationally, they play an important role in recognition, signaling, immunological response and cell-cell interaction. Improper sialylations have been associated with several diseases including cancer. In the post genomics and proteomics era, sialoglybiology has become more and more important in deciphering health and disease conditions.

  • Tumor Vascularization

    • 1st Edition
    • Domenico Ribatti + 1 more
    • English
    Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.

  • Mesenchymal Stem Cells in Human Health and Diseases

    • 1st Edition
    • Ahmed El-Hashash
    • English
    Mesenchymal Stem Cells in Human Health and Diseases provides a contemporary overview of the fast-moving field of MSC biology, regenerative medicine and therapeutics. MSCs offer the potential to dramatically reduce human suffering from disease. Numerous MSC-based studies are ongoing each year, each offering hope for novel treatments in human disease. This book provides information on MSC application in well-studied human diseases and tissue repair/regeneration and recent advances in their research and treatment. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in our understanding of MSC biology.

  • Medical Data Sharing, Harmonization and Analytics

    • 1st Edition
    • Vasileios Pezoulas + 2 more
    • English
    Medical Data Sharing, Harmonization and Analytics serves as the basis for understanding the rapidly evolving field of medical data harmonization combined with the latest cloud infrastructures for storing the harmonized (shared) data. Chapters cover the latest research and applications on data sharing and protection in the medical domain, cohort integration through the recent advancements in data harmonization, cloud computing for storing and securing the patient data, and data analytics for effectively processing the harmonized data.

  • Neuroimaging Atlas of the Human Brain

    MRI, DTI, and Histology
    • 1st Edition
    • Jacopo Annese
    • English
    The field of human brain mapping is exhibiting an increased focus on the study of neural functional architecture at the system level and on individual neurological characteristics. rather than pm population-based averages. This new direction has resulted in a need for a new brain atlas that incorporates correlated radiologic and histological images representing the whole brain. Initiatives such as the Human Connectome Project are based on non-invasive techniques that afford images of the brain only at the macroscopic level, creating a growing need for an atlas that provides histological images of entire (coronal) sections that can then be easily compared to corresponding MRI and DTI images, making the correlation across modalities direct and intuitive. Neuroimaging Atlas of the Human Brain: MRI, DTI, and Histology is just such an atlas, representing the first market offering of histologic, radiologic, and labeled anatomical images of the same, entire human brain.

  • Mosby's Sterile Compounding for Pharmacy Technicians

    Principles and Practice
    • 2nd Edition
    • Karen Davis
    • English
    Gain a complete introduction to institutional pharmacy practice and efficiently prepare for the new sterile compounding certification exam! Comprehensively covering sterile products, aseptic technique, and the workings of the sterile compounding facility, Mosby’s Sterile Compounding for Pharmacy Technicians: Principles and Practice, 2nd Edition, focuses on safe and accurate practice. This edition has expanded and updated coverage to address preparation, processing, medications, technique, and documentation, with review, analysis, and application of <USP 797>, <USP 800>, and <USP 825> and additional content on waste management, workflow, safety and compliance, billing and reimbursement, and emergency management. Illustrations abound, and content is brought to life with an updated art program, step-by-step procedures, and technician notes and alerts. Certification review questions are included with each chapter, and online student and instructor resources round out the offering.

  • Earth-like Exoplanets

    • 1st Edition
    • Volume 3
    • Paul A. Mason + 1 more
    • English
    Earth-like Exoplanets, Volume Three reviews the rapidly expanding study of exoplanets and what these new worlds have revealed regarding planet types located in diverse circumstellar and planetary environments. Currently, Earth remains the only example for life on planets, but other Solar System bodies - Venus, Mars, and the Moon - provide important information about where and when life is possible. As life on Earth and the lack of detected life on bodies in, or near, the habitable zone of the Sun supply much of what is directly known about astrobiology, the possibilities of finding life out there is ripe for new discovery.

  • Cellular Signalling in Cancer Metastasis

    • 1st Edition
    • English
    Cellular Signalling in Cancer Metastasis provides the reader with in-depth information on the cellular signaling mechanisms responsible for cancer metastasis. While significant progress has been made in understanding the mechanisms responsible for metastasis, the lack of a comprehensive book compiling these aspects was necessary, hence the development of this timely resource. This book is intended to help entry level researchers, from graduate students, postdocs and early career scientists, but is detailed enough to be considered by seasoned scientists. It provides the reader with the current knowledge available on the subject and stimulates others to take up investigations on understanding cancer metastasis.

  • Crop Genome Editing Using CRISPR/Cas9

    Theory and Practice
    • 1st Edition
    • Ramalingam Ravindhran + 2 more
    • English
    Crop Genome Editing Using CRISPR/Cas9: Theory and Practice is a highly useful reference for implementing genome engineering technologies, particularly CRISPR related projects in agricultural crops and other plants. This book provides an introduction to CRISPR’s basic science and applied aspects, along with detailed protocols. It presents a detailed workflow, beginning with genome sequence retrieval and then mutation analysis in genome edited events using sequencing tools. The book helps those in the field methodically plan, design and conduct experiments. This practical guide will dramatically help researchers in accelerating conventional plant breeding programs.

  • Remote Sensing Technologies as Applied to Wetlands

    • 1st Edition
    • Emilio Ramirez Juidias
    • English
    Remote Sensing Technologies Applied to Wetlands presents the challenges and opportunities relating to the restoration of freshwater and estuarine wetlands in natural, agricultural and urban environments due to a range of contributing factors, including climate change and human and industrial factors. The author uses his own pioneering research to show how remote sensing techniques can be applied to these key areas of biodiversity. Through descriptions of the latest techniques in remote sensing, this book covers the existing vacuum surrounding the study of salt marshes and wetlands through a technical, but easy to follow narrative that includes successful, scenario-based case studies.Scientists and masters and doctorates students studying wetlands and remote sensing will find this to be an ideal resource.

  • Looking at Ribozymes

    From Atomic to Molecular and Cellular Scales
    • 1st Edition
    • Fabrice Leclerc + 1 more
    • English
    Looking at Ribozymes: From Atomic to Molecular and Cellular Scales introduces ideas on how ribozymes “work” through a comparison of their common features and specificities. It covers how the (macro) molecular organization at different scales make it possible, what function they carry, where they are found, how they evolved, and how have they been used. The book emphasizes common and specific features of natural and artificial ribozymes, from the basics, to more advanced aspects, making it ideal for undergraduates, grad students and researchers. Specific sections cover different areas of research, from the atomic scale (catalysis), to the molecular (folding, dynamics).In addition, other sections cover macromolecular and cellular scales (dynamics, long-range interactions, self-assembly, cellular processes). The book is not a directory of ribozymes, it instead provides comparative knowledge, including the interdependent relationships between the different scales of description based on different experimental and theoretical approaches.

  • The Aptamers Ligands

    Powerful Tools from Molecular Evolution
    • 1st Edition
    • Gerald Perret + 1 more
    • English
    The Aptamers Ligands: Powerful Tools from Molecular Evolution discusses these short, single strand oligonucleotides that can fold in a three-dimensional conformation and how they can provide a precise molecular recognition of a given target. These nucleic acid based ligands are identified from large naive combinatorial oligonucleotide libraries using a well-established technology called SELEX (systematic evolution of ligands by exponential enrichment). Aptamers can be extremely specific towards their target molecule with high selectivity and proper affinity dissociation constants. Moreover, they can be selected to recognize a high diversity of molecules, from very small compounds, to large macromolecules, such as proteins.

  • Mechanobiology

    From Molecular Sensing to Disease
    • 1st Edition
    • Glen L. Niebur
    • English
    Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology.

  • Neurofeedback and Neuromodulation Techniques and Applications

    • 2nd Edition
    • Robert Coben + 1 more
    • English
    Neurofeedback and Neuromodulation Techniques and Applications, Second Edition, presents the latest techniques, analysis and applications to specific patient populations and disorders. The book will serve as an extensive reference on neuromodulation techniques with its discussions on innovative applications that either currently exist or are in development. Top scholars in the field offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional. This information is critical for neurosurgeons, neuropsychologists, neurophysiologists, clinical psychologists, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area.

  • Clinical and Basic Neurogastroenterology and Motility

    • 1st Edition
    • Satish S.C. Rao + 2 more
    • English
    Clinical and Basic Neurogastroenterolog... and Motility is a state-of-the-art, lucidly written, generously illustrated, landmark publication that comprehensively addresses the underlying mechanisms and management of common adult and pediatric motility disorders. These problems affect 50% of the population and include conditions such as dysphagia, achalasia, gastroesophageal reflux disease, gastroparesis, irritable bowel syndrome (IBS), gas and bloating, SIBO, constipation and fecal incontinence. The book brings together international experts and clinician scientists, epitomizing their years of wisdom into a concise yet practical text that is delivered in two distinct sections, basic and clinical. It fulfills a large unmet need, and bridges a long-awaited knowledge gap among trainees, clinicians, scientists, nurses and technicians, earnestly engaged in this field.

  • Clinical Molecular Medicine

    Principles and Practice
    • 1st Edition
    • Dhavendra Kumar
    • English
    Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances.

  • Diet and Fighting Bladder Cancer

    • 1st Edition
    • Maurice P. Zeegers
    • English
    This book is partly based on research funded by Wereld Kanker Onderzoek Fonds based in the Netherlands and administered by the World Cancer Research Fund International grant program. Every year half a million of people worldwide are diagnosed with bladder cancer. With the recent zeitgeist of the self-empowered, intelligent patient who wishes to be well-informed, many cancer patients do not solely want to rely on decisions taken by medical practitioners, but actively participate in the journey from sickness to health or disease. While no books about the relationship between diet and bladder cancer currently exist, the poor quality of the existing information about the relationship between diet and health is shocking. Much of the information is exaggerated, not evidence-based, misleading and sometimes even incorrect. Dr. Maurice Zeegers, one of the world leading bladder cancer epidemiologists, and his co-authors set the record straight with this book on Diet and Fighting Bladder Cancer. Their aim is to provide purely evidence-based information about the relationship between diet and bladder cancer. The primary audience is bladder cancer patients who wish to be well-informed, although clinicians and healthcare workers may also find the book an interesting read. The book gives an honest reflection on what scientists know, but also what they don’t yet know about how diet contributes to all stages of this important disease. Although science-based, the book is written in an easy-to-read format, illustrated with practical recipes.

  • Principles of Parenteral Solution Validation

    A Practical Lifecycle Approach
    • 1st Edition
    • Igor Gorsky + 1 more
    • English
    Principles of Parenteral Solution Validation: A Practical Lifecycle Approach covers all aspects involved in the development and process validation of a parenteral product. By using a lifecycle approach, this book discusses the latest technology, compliance developments, and regulatory considerations and trends, from process design, to divesting. As part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin, this book incorporates numerous case studies and real-world examples that address timely problems and offer solutions to the daily challenges facing practitioners in this area.

  • Fruit Crops

    Diagnosis and Management of Nutrient Constraints
    • 1st Edition
    • Anoop Kumar Srivastava + 1 more
    • English
    Fruit Crops: Diagnosis and Management of Nutrient Constraints is the first and only resource to holistically relate fruits as a nutritional source for human health to the state-of-the-art methodologies currently used to diagnose and manage nutritional constraints placed on those fruits. This book explores a variety of advanced management techniques, including open field hydroponic, fertigation/bio-fert... the use of nano-fertilizers, sensors-based nutrient management, climate- smart integrated soil fertility management, inoculation with microbial consortium, and endophytes backed up by ecophysiology of fruit crops. These intricate issues are effectively presented, including real-world applications and future insights.

  • Bioengineering Innovative Solutions for Cancer

    • 1st Edition
    • Sylvain Ladame + 1 more
    • English
    Bioengineering Innovative Solutions for Cancer bridges the gap between bioengineering and cancer biology. It focuses on a ‘bottom up’ understanding of the links between molecules, cells, tissues, organs, organisms, and health and functions—all within a bioengineering context. Chapters cover the main methods, technologies and devices that could help diagnose cancer sooner (e.g., ultrasensitive imaging and sensing technologies) and helpful treatments (e.g., new, more targeted therapies). The book takes an interdisciplinary approach that is ideal for those who need the latest information on design techniques and devices that help treat cancer using new, more targeted therapies. By covering the many different ways engineers can deliver innovative solutions to tackle cancer, this book is a valuable read for researchers who have an ambition to make an impact on people’s life in either an academic or industrial setting.

  • Maternal Immunization

    • 1st Edition
    • Elke Leuridan + 2 more
    • English
    Immunization during pregnancy with currently recommended vaccines prevents infection in the mother, the unborn fetus, and the young infant, and there is an increasing focus from different stakeholders to use this approach for other infections of importance to protect these vulnerable groups. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of vaccines in pregnancy, safety, immunogenicity (immunology), timing to vaccinate, repeat doses, protective effects in the mother, fetus, and infant, and public acceptance and implementation, of existing and of future vaccines.

  • Neuroimaging, An Issue of Neurologic Clinics

    • 1st Edition
    • Volume 38-1
    • Laszlo Mechtler
    • English
    This issue of Neurologic Clinics, guest edited by Laszlo L. Mechtler, will cover key topics in Neuroimaging. This issue is one of four selected each year by our series consulting editor, Dr. Randolph W. Evans. Topics discussed in this issue will include: Future of Neuroimaging, Neuroimaging for the Neurologist, Imaging in Pregnancy, Multiple Sclerosis Mimic, Diseases that cause Dementia, Acute Stroke, DBS, NPH and Hydrocephalus, Venous Disease of the Brain, Cranial Nerve Imaging, and Neuro-ultrasonograph... among others.

  • Carbon Dioxide

    • 1st Edition
    • Volume 37
    • English
    Carbon Dioxide, Volume 37 in the Fish Physiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Historic, current-day and future CO2 environments and their dynamics in marine and freshwater ecosystems, CO2 sensing, Acid-base physiology and CO2 homeostasis: regulation and compensation, CO2 and calcification processes in fish, The physiology of behavioral impacts of high CO2, Effects of high CO2 on metabolic rates, aerobic scope and swimming performance, Internal spatial and temporal CO2 effects: feeding and alkaline tide, O2 in aquaculture: CO2 dynamics and fish health, and much more.

  • Multiresponsive Behavior of Biomembranes and Giant Vesicles

    • 1st Edition
    • Volume 30
    • English
    Biomembranes consist of molecular bilayers with many lipid and protein components. The fluidity of these bilayers allows them to respond to different environmental cues by changing their local molecular composition as well as their shape and topology. On the nanometer scale, this multi-responsive behavior can be studied by molecular dynamics simulations, which provide both snapshots and movies of the bilayer conformations. The general conceptual framework for these simulations is provided by the theory of curvature elasticity. The latter theory also explains the behavior of giant vesicles as observed by optical microscopy on the micrometer scale. The present volume describes new insights as obtained from recent developments in analytical theory, computer simulations, and experimental approaches. The seven chapters of the volume are arranged in a bottom-up manner from smaller to larger scales. These chapters address the refined molecular dynamics and multiscale modeling of biomembranes, their morphological complexity and adhesion, the engulfment and endocytosis of nanoparticles, the fusion of giant unilamellar vesicles, as well as recent advances in microfluidic technology applied to model membranes.

  • Advances in Marine Biology

    • 1st Edition
    • Volume 84
    • Jean-Francois Hamel
    • English
    Advances in Marine Biology, Volume 84, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography.

  • Parkinsonism Beyond Parkinson's Disease

    • 1st Edition
    • Volume 149
    • English
    Parkinsonism beyond Parkinson's Disease, Volume 149, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including How to approach a patient with parkinsonism – red flags for atypical parkinsonism, The ‘classic’ atypical parkinsonian disorders, Classification of atypical parkinsonism per pathology vs. phenotypes, Progressive supranuclear palsy, Corticobasal degeneration, Multiple system atrophy, Atypical parkinsonism in other sporadic and genetic neurodegenerative diseases, Sporadic ‘Atypical’ Parkinson’s disease, and much more.

  • The Portfolio Diet for Cardiovascular Disease Risk Reduction

    An Evidence Based Approach to Lower Cholesterol through Plant Food Consumption
    • 1st Edition
    • Wendy Jenkins + 3 more
    • English
    The Portfolio Diet for Cardiovascular Disease Risk Reduction: An Evidence Based Approach to Lower Cholesterol through Plant Food Consumption examines the science of this recommended dietary approach to reduce cholesterol in addition to other risk factors for cardiovascular disease. With a thorough examination into the scientific rationale for the use of this diet, discussions are included on the experimental findings both for the diet as a whole, and its four principle food components: nuts and seeds, plant based protein, viscous fibers, and plant-sterol-enriche... foods. Environmental and ethical considerations of the diet are also discussed, showing the ramifications of food choice on health and beyond. Referenced with data from the latest relevant publications and enhanced with practical details (including tips, dishes, and menus), the reader is enabled to meet the goals of cholesterol lowering and cardiovascular disease risk reduction while also taking the health of the planet into consideration.

  • Human Papillomavirus

    Proving and Using a Viral Cause for Cancer
    • 1st Edition
    • David Jenkins + 1 more
    • English
    Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine.

  • Pangolins

    Science, Society and Conservation
    • 1st Edition
    • English
    Pangolins: Science, Society and Conservation brings together experts from around the world to document the most up-to-date scientific knowledge on pangolins and their conservation. It chronicles threats facing the species, explores the current initiatives required to protect them, and looks ahead at the future of pangolin science and conservation efforts. Led by a team of editors with more than 20 years collective experience in pangolin conservation, this book includes accounts of the species’ evolution, morphology, and systematics. It discusses the role of pangolins in historically symbolic, mythological, and ritualistic practices across Africa, Asia, and Europe, as well as contemporary practices including international trafficking. Chapters in the latter portion of this book focus on conservation solutions, including law enforcement and international policy, behavior change, local community engagement, ex situ conservation, tourism, and other interventions needed to secure the future of the species. Pangolins: Science, Society and Conservation is the latest volume in Elsevier’s species-specific series, Biodiversity of the World: Conservation from Genes to Landscapes. This book is a valuable resource for researchers and students in species conservation science, planning, and policymaking.

  • Dengue Virus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 1 more
    • English
    Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world’s population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic.

  • The Zebrafish in Biomedical Research

    Biology, Husbandry, Diseases, and Research Applications
    • 1st Edition
    • Samuel Cartner + 5 more
    • English
    The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.

  • Medical Semiology Guide of the Cardiovascular System and the Hematologic System

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology Guide of the Cardiovascular System and the Hematologic System provides a comprehensive understanding of medical semiology in the cardiovascular and hematologic systems. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference for clinicians.

  • The Theory of Endobiogeny

    Volume 4: Bedside Handbook
    • 1st Edition
    • Kamyar M. Hedayat + 2 more
    • English
    The Theory of Endobiogeny Volume 4: Bedside Handbook concisely presents core elements of the theory and practice of clinical Endobiogeny. It is an essential reference for Endobiogenists and for integrative medicine practitioners looking to expand their practice. Signs, symptoms and biology of function indexes are correlated to each other according to principles of integrative endocrinology and physiology. Over 20 common illnesses are succinctly summarized to be read in under 10 minutes conveying the essence of neuroendocrine causes, mechanisms and effects, followed by prioritization of Endobiogenic treatments based on 40+ years of clinical experience. Finally, for exemplary prescriptions, alternate plants are proposed based on the context of the specific illness. A succinct materia medica summarizes the essence and key role of nearly 80 medicinal plants used in clinical Endobiogeny, offering new insights for experienced prescribers and clear guidance for those new to the usage of medicinal plants. The Theory of Endobiogeny Volume 4 provides clinicians and researchers with a concise handbook covering the application of Endobiogeny in current clinical practice.

  • Global Change and Forest Soils

    Cultivating Stewardship of a Finite Natural Resource
    • 1st Edition
    • Volume 36
    • English
    Global Change and Forest Soils: Cultivating Stewardship of a Finite Natural Resource, Volume 36, provides a state-of-the-science summary and synthesis of global forest soils that identifies concerns, issues and opportunities for soil adaptation and mitigation as external pressures from global changes arise. Where, how and why some soils are resilient to global change while others are at risk is explored, as are upcoming train wrecks and success stories across boreal, temperate, and tropical forests. Each chapter offers multiple sections written by leading soil scientists who comment on wildfires, climate change and forest harvesting effects, while also introducing examples of current global issues. Readers will find this book to be an integrated, up-to-date assessment on global forest soils.

  • Immunobiology of Dendritic Cells Part B

    • 1st Edition
    • Volume 349
    • English
    Immunobiology of Dendritic Cells Part B, Volume 349 in the International Review of Cell and Molecular Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Sugarcane Biorefinery, Technology and Perspectives

    • 1st Edition
    • Fernando Santos + 3 more
    • English
    Sugarcane Biorefinery, Technology and Perspectives provides the reader with a current view of the global scenario of sugarcane biorefinery, launching a new expectation on this important crop from a chemical, energy and sustainability point-of-view. The book explores the existing biorefinery platforms that can be used to convert sugarcane to new high value added products. It also addresses one of today's most controversial issues involving energy cane, in addition to the dilemma "sugar cane vs. food vs. the environment", adding even more value in a culture that is already a symbol of case study around the world. Focusing on the chemical composition of sugarcane, and the production and processes that optimize it for either agricultural or energy use, the book is designed to provide practical insights for current application and inspire the further exploration of options for balancing food and fuel demands.

  • Encyclopedia of Biomedical Gerontology

    • 1st Edition
    • Suresh Rattan
    • English
    Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention.

  • Medical Semiology Guide of the Renal System

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology Guide of the Renal System provides a comprehensive understanding of medical semiology in the renal system. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference guide for clinicians in practice.

  • Sustainable Agriculture

    Advances in Plant Metabolome and Microbiome
    • 1st Edition
    • Javid Ahmad Parray + 1 more
    • English
    Sustainable Agriculture: Advances in Plant Metabolome and Microbiome focuses on the advancement of basic and applied research related to plant-microbe interaction and their implementation in progressive agricultural sustainability. The book also highlights the developing area of bioinformatics tools for the interpretation of metabolome, the integration of statistical and bioinformatics tools to manage huge generating data, metabolite profiling, and key signaling-driven substances, along with a section on the role of key biosynthetic pathways. Focused on selecting positive and effective interactive core-microbiome which will be adaptive and sustainable, this book will help researchers further improve the quality and productivity of crops through sustainable agriculture.

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