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Elsevier

Tumor Vascularization

  • 1st Edition - January 7, 2020
  • Latest edition
  • Editors: Domenico Ribatti, Francesco Pezzella
  • Language: English

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: th… Read more

Description

Tumor Vascularization discusses the different types of growth of tumor blood vessels and their implications on research and healthcare. The book is divided into three parts: the first one, General Mechanisms, discusses different vessel growth mechanisms, such as sprouting angiogenesis, non-angiogenesis dependent growth, intussusceptive microvascular growth, vascular co-option and vasculogenic mimicry. The second and third parts, entitled Clinical Implications and Therapeutic Implications are dedicated to translating recent findings in this field to patient treatment and healthcare. This book is a valuable source for cancer researchers, oncologists, graduate students and members of the biomedical field who are interested in tumor progression and blood vessels.

Key features

  • Explains new, non-orthodox concepts recently developed and related to the modality of growth of tumor blood vessels
  • Provides information on the types of angiogenesis, non-angiogenesis dependent growth and vascular co-option, discussing both their similarities and differences
  • Encompasses a discussion on clinical implications of tumor vascularization to translate research findings into treatment

Readership

cancer researchers, medical scientists, clinicians, graduate students

Table of contents

PrefaceDomenico Ribatti and Francesco Pezzella1. Sprouting and non-sprouting angiogenesis in tumorsDomenico Ribatti and Francesco Pezzella2. Nonangiogenic tumor growthPeter Vermeulen and Francesco Pezzella3. Vascular co-optionPedro García-Gómez and Manuel Valiente4. Pericyte mimicry: an embryonic-like mechanism for tumor metastasis Claire Lugassy, Hynda Kleinman and Raymond Barnhill5. Vasculogenic mimicryYun Cao and Chao-Nan Miles Qian6. Postnatal vasculogenesisLatetitia Andrique, Gaelle Recher, Pierre Nassoy and Andreas Bikfalvi7. The perivascular nicheAlia Komsany and Francesco Pezzella8. Zebrafish as an experimental model to study tumor angiogenesis Jessica Guerra, Chiara Tobia, Marco Presta and Andrea Barbieri9. Clinical implications Adrian Harris

Review quotes

"This will be a useful book for scientists and clinicians interested in angiogenesis and related mechanisms. The information is current and the topics are well covered. I am not aware of another recent book focused solely on this subject."—Doody

Product details

  • Edition: 1
  • Latest edition
  • Published: January 7, 2020
  • Language: English

About the editors

DR

Domenico Ribatti

Domenico Ribatti was awarded his M.D. degree in October 1981, with full marks. In 1983, D.R. joined the Medical School as Assistant at the Institute of Human Anatomy, University of Bari. In 1984, he took the specialization in Allergology. In 1989, he spent one year in Geneva, working at the Department of Morphology (Prof. R. Montesano). In 2008, he received the honoris causa degree in Medicine and Pharmacy form the University of Timisoara (Romania). D.R. is author of 866 publications as reported in PUBmed and contributed to 50 chapters to books. Overall, his papers have been cited 51153 times. He has published many books with both Elsevier and Springe
Affiliations and expertise
Full Professor of Human Anatomy, University of Bari Medical School, Bari, Italy

FP

Francesco Pezzella

Francesco Pezzella is a histopathologist and is currently Professor of Tumour Pathology at Oxford. He worked in the past on the pathology of HIV (at the time HTLV III) infection and molecular alterations in lymphoma. Because of his friends pushing him into the field of cancer and blood vessels, eventually he discovered in the mid-nineties, by pure chance, the tumours growing without angiogenesis.
Affiliations and expertise
Professor of Tumour Pathology, Nuffield Division of Clinical Laboratory Science-Radcliffe Department of Medicine, University of Oxford, UK

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