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Elsevier

Books in Life sciences

  • Recent Advances in Hemodynamics and Blood Mimetics

    • 1st Edition
    • João Mário Rodrigues Miranda + 4 more
    • English
    Recent Advances in Hemodynamics and Blood Mimetics is a comprehensive compilation of recent developments in biofluid mechanics and biomimetics, covering topics such as numerical modeling, biomedical applications of microfluidics, biomimetic flows, biomedicine applications, and organ-on-chip technology. The book explores blood hemodynamics at different scales, including application to diseases, the relationship between blood biomechanics and rheology, the mimetization of blood properties at arterial and capillary level, including the study of blood mechanical and flow properties, flow and surface properties of blood cells, and mimetization of these same properties in fluid/particle systems.These concepts are applied to the development of organ-on-chip to improve the replication of biological processes in the human body. The book organizes recent knowledge on hemodynamics and blood mimetics and is representative of the different lines of research in the field, showing an integrated view of blood biomechanics encompassing all scales to create a valuable resource where different research lines can be found and their principles understood.

  • Novel Bioproducts through Metabolic Engineering of Secondary Metabolites

    • 1st Edition
    • Yogesh K. Ahlawat + 3 more
    • English
    Novel Bioproducts through Metabolic Engineering of Secondary Metabolites provides comprehensive coverage of the latest developments in metabolic engineering and secondary metabolites, along with their roles in industrial product development. Sections cover the pivotal role secondary metabolites play in nature, their diverse classes, their significant applications in industry and medicine, and the fundamentals of metabolic engineering. Additional coverage includes biosynthetic pathways of secondary metabolites, strain development and optimization, rational design of pathway modifications, industrial enzymes and chemicals from metabolic engineering, and cutting-edge tools and technologies in metabolic engineering. The book concludes with a roadmap for the future of metabolic engineering, exploring emerging trends such as CRISPR and genome editing, artificial intelligence applications, and the evolving landscape of synthetic biology and bioeconomy.

  • Phytochemicals and Gut Health

    Evidence and Opportunities for Gastrointestinal Management
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Phytochemicals and Gut Health: Evidence and Opportunities for Gastrointestinal Management highlights specific plant phytochemicals, their bioactive compounds, and the influence they have on the gut-brain axis. By exploring sources, production, mechanisms of action, and clinical applications, the book uncovers how certain bioactives can optimize health and improve gastrointestinal diseases while reducing the side effects and limited efficacy of current medical treatments. The book's authors identify different classes of plant-based phytochemicals such as phenolic metabolites, alkaloids, terpenoids, and glucosinolates while demonstrating a better understanding of the gut-nutraceutical axis that can improve microbiota for GI disorders, and more. Readers will also gain important perspectives on mechanisms of action and the synergistic effects phytochemicals have on cardiovascular and neurological health.

  • Functionalized Drug Delivery Systems

    • 1st Edition
    • Umesh Gupta + 1 more
    • English
    Functionalized Drug Delivery Systems delves into the potential of various functionalized drug delivery systems, such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS. It offers a comprehensive guide from basic concepts to advanced surface engineering techniques. The book covers liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes, and ethosomes, concluding with a chapter on the regulatory framework. This invaluable resource is perfect for pharmaceutical researchers and graduate students keen on advancing their understanding and application of these innovative drug delivery methods. The book also provides consolidated literature reviews, making it a foundational text for new researchers.Its chapters are dedicated to specific techniques, offering detailed insights into each method. Readers will gain knowledge on improving drug absorption and targeted delivery, supported by practical examples and case studies. The final chapter on regulatory frameworks ensures compliance and best practices in developing functionalized drug delivery systems. This book is an essential read for anyone in the field of pharmaceutical research.

  • An Introduction to Applied Clinical Ethics in Pathology and Laboratory Medicine

    A Case-Based Approach
    • 1st Edition
    • Ifeoma U. Perkins
    • English
    An Introduction to Applied Clinical Ethics in Pathology and Laboratory Medicine: A Case-Based Approach offers an organized pragmatic approach to processing ethical dilemmas that frequently occur in pathology and laboratory medicine in a systematic way. This is a novel resource strategically crafted in a case-based format to help readers confidently reach potential solutions with strong ethical reasoning that not only further quality patient care but honor the good intentions of pathologists and laboratorians. Readers will gain confidence in their ability to think critically about complex problems in pathology that create ethical conflict. This book is for healthcare providers, practicing anatomic and clinical pathologists, pathology residents and fellows, pathology educators and graduate medical education program directors, students of allied health sciences, researchers, laboratory technologists, and any members of the clinical care team who utilize laboratory services.

  • Biophysics of Life

    Origin and Evolution
    • 1st Edition
    • Mohammad Ashrafuzzaman
    • English
    Biophysics of Life: Origin and Evolution explores the biophysical mechanisms involved in the formation and evolution of life. The book considers a range of topics, including the history of life’s physical evolution, physics laws governing the origins of life, biophysical and biochemical principles in the building blocks of life, biomolecular mutations, and physics and quantum mechanical interpretations of evolution. Biophysical and biochemical techniques for sequencing life’s origins are also explored, as well as bioinformatics and AI algorithms tracking the origins of life. Additionally, biophysics of life in extreme conditions is considered, as well as biophysics of artificial life.As physics laws govern most of the molecular processes associated with biological life, this book seeks to investigate the origin and development of life through that lens, considering how life’s maturation happened as a result of the coordinated actions of physics, chemistry, and biology. This is an important reference for researchers working across biophysics, biochemistry, molecular biology, cell biology, and in related fields.

  • Therapeutic Potential of Medicinal Plants

    The Science Behind Natural Remedies
    • 1st Edition
    • Vera Popović + 1 more
    • English
    When synthetic drugs produce adverse side effects, practitioners may look to natural alternatives to alleviate symptoms or complement existing treatment. Therapeutic Potential of Medicinal Plants: The Science Behind Natural Remedies, investigates the bioactive compounds and functionality of medicinal plants and herbs which are recommended to help certain health conditions and overall well-being while highlighting cultivation that can be done sustainably to promote biodiversity conservation. Written by over 50 experts in the fields of nutrition, organic food, fertility, phytopharmacology, biotechnology, nanotechnology, plant botanicals, and herbal medicine, “Therapeutic Potential of Medicinal Plants: The Science Behind Natural Remedies,” introduces readers to the the chemical composition of over 75 plants, herbs, grains and seeds while highlighting their anti-inflammatory, antimicrobial, antioxidant, and immunomodulatory effects to improve overall well being and manage certain conditions such as diabetes, osteoarthritis, cardiovascular and neurodegenerative diseases. Bioactive compounds, essential oils and phytochemicals in certain plants and marine compounds are reviewed for their efficacy to help improve gynecological health, alleviate menopausal symptoms and lower blood pressure. The book also discusses the toxicity and safety implications associated with the use of medicinal herbs during pregnancy and other life stages.

  • Preventable Medical Errors

    The Role of Different Sciences in Medical Education and Practice
    • 1st Edition
    • Erwin B. Montgomery Jr.
    • English
    Preventable Medical Errors: The Role of Different Sciences in Medical Education and Practice addresses the issues of staying up to date with evolving medical practices, by providing practical examples linked to real-world patient safety concerns and illustrating theoretical discussions with clear clinical practice scenarios. The book is divided into two sections, Part 1 - How Did It Come To This? and Part 2 - Where Does It Go From Here?; which guide the reader through how we got here historically and how we can navigate our way out using the tools the author presents. Thus paving the way, bridging a gap between theory and practice, while emphasizing the importance of patient safety. Written for all medical professionals, at the forefront of postmodern and scientific medical advancements, to ultimately improve clinical outcomes and reduce preventable medical errors.

  • Cyclic Peptides

    • 1st Edition
    • Volume 723
    • English
    Cyclic Peptides, Volume 721 covers peptide structures and their enhancement, stability, specificity, and overall functionality. As a growing suite of computational and experimental tools support the discovery and optimization of these molecules, ranging from well-established modeling platforms to emerging deep-learning algorithms that expand design possibilities, this book aims to provide a comprehensive overview of cyclic peptide research, covering fundamental principles, production strategies, and the latest technological advances in both synthetic and computational realms.Cyclic peptides are a powerful approach to constraining peptide structures, enhancing their stability, specificity, and overall functionality. They can be generated through diverse techniques—including chemical synthesis, mRNA display, and DNA display—that enable the creation of tailored peptide libraries.

  • Medications for Older Persons

    Recommendations, Harms, Evidence
    • 1st Edition
    • Roger Thomas
    • English
    Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.

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