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Elsevier

Books in Life sciences

  • Parkinsonism Beyond Parkinson's Disease

    • 1st Edition
    • Volume 149
    • English
    Parkinsonism beyond Parkinson's Disease, Volume 149, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including How to approach a patient with parkinsonism – red flags for atypical parkinsonism, The ‘classic’ atypical parkinsonian disorders, Classification of atypical parkinsonism per pathology vs. phenotypes, Progressive supranuclear palsy, Corticobasal degeneration, Multiple system atrophy, Atypical parkinsonism in other sporadic and genetic neurodegenerative diseases, Sporadic ‘Atypical’ Parkinson’s disease, and much more.

  • Artificial Intelligence for Computational Modeling of the Heart

    • 1st Edition
    • Tommaso Mansi + 2 more
    • English
    Artificial Intelligence for Computational Modeling of the Heart presents recent research developments towards streamlined and automatic estimation of the digital twin of a patient’s heart by combining computational modeling of heart physiology and artificial intelligence. The book first introduces the major aspects of multi-scale modeling of the heart, along with the compromises needed to achieve subject-specific simulations. Reader will then learn how AI technologies can unlock robust estimations of cardiac anatomy, obtain meta-models for real-time biophysical computations, and estimate model parameters from routine clinical data. Concepts are all illustrated through concrete clinical applications.

  • Multiresponsive Behavior of Biomembranes and Giant Vesicles

    • 1st Edition
    • Volume 30
    • English
    Biomembranes consist of molecular bilayers with many lipid and protein components. The fluidity of these bilayers allows them to respond to different environmental cues by changing their local molecular composition as well as their shape and topology. On the nanometer scale, this multi-responsive behavior can be studied by molecular dynamics simulations, which provide both snapshots and movies of the bilayer conformations. The general conceptual framework for these simulations is provided by the theory of curvature elasticity. The latter theory also explains the behavior of giant vesicles as observed by optical microscopy on the micrometer scale. The present volume describes new insights as obtained from recent developments in analytical theory, computer simulations, and experimental approaches. The seven chapters of the volume are arranged in a bottom-up manner from smaller to larger scales. These chapters address the refined molecular dynamics and multiscale modeling of biomembranes, their morphological complexity and adhesion, the engulfment and endocytosis of nanoparticles, the fusion of giant unilamellar vesicles, as well as recent advances in microfluidic technology applied to model membranes.

  • The Portfolio Diet for Cardiovascular Disease Risk Reduction

    An Evidence Based Approach to Lower Cholesterol through Plant Food Consumption
    • 1st Edition
    • Wendy Jenkins + 3 more
    • English
    The Portfolio Diet for Cardiovascular Disease Risk Reduction: An Evidence Based Approach to Lower Cholesterol through Plant Food Consumption examines the science of this recommended dietary approach to reduce cholesterol in addition to other risk factors for cardiovascular disease. With a thorough examination into the scientific rationale for the use of this diet, discussions are included on the experimental findings both for the diet as a whole, and its four principle food components: nuts and seeds, plant based protein, viscous fibers, and plant-sterol-enriche... foods. Environmental and ethical considerations of the diet are also discussed, showing the ramifications of food choice on health and beyond. Referenced with data from the latest relevant publications and enhanced with practical details (including tips, dishes, and menus), the reader is enabled to meet the goals of cholesterol lowering and cardiovascular disease risk reduction while also taking the health of the planet into consideration.

  • Essential Concepts in Molecular Pathology

    • 2nd Edition
    • William B. Coleman + 1 more
    • English
    Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine.

  • Human Papillomavirus

    Proving and Using a Viral Cause for Cancer
    • 1st Edition
    • David Jenkins + 1 more
    • English
    Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine.

  • Pangolins

    Science, Society and Conservation
    • 1st Edition
    • English
    Pangolins: Science, Society and Conservation brings together experts from around the world to document the most up-to-date scientific knowledge on pangolins and their conservation. It chronicles threats facing the species, explores the current initiatives required to protect them, and looks ahead at the future of pangolin science and conservation efforts. Led by a team of editors with more than 20 years collective experience in pangolin conservation, this book includes accounts of the species’ evolution, morphology, and systematics. It discusses the role of pangolins in historically symbolic, mythological, and ritualistic practices across Africa, Asia, and Europe, as well as contemporary practices including international trafficking. Chapters in the latter portion of this book focus on conservation solutions, including law enforcement and international policy, behavior change, local community engagement, ex situ conservation, tourism, and other interventions needed to secure the future of the species. Pangolins: Science, Society and Conservation is the latest volume in Elsevier’s species-specific series, Biodiversity of the World: Conservation from Genes to Landscapes. This book is a valuable resource for researchers and students in species conservation science, planning, and policymaking.

  • Dengue Virus Disease

    From Origin to Outbreak
    • 1st Edition
    • Adnan I. Qureshi + 1 more
    • English
    Dengue Virus Disease: From Origin to Outbreak provides a detailed accounting of one of the world's fastest growing infections. According to the World Health Organization, Dengue virus incidence has increased 30-fold over the past 50 years, with up to 50 to 100 million infections occurring annually in over 100 endemic countries. This estimate puts nearly half the world’s population at risk. This book reviews the history, clinical and diagnostic aspects of dengue virus, also presenting our current knowledge on the pathophysiology of severe dengue and addressing the importance of dengue virus infections in those traveling to parts of the world where it is endemic.

  • The Theory of Endobiogeny

    Volume 4: Bedside Handbook
    • 1st Edition
    • Kamyar M. Hedayat + 2 more
    • English
    The Theory of Endobiogeny Volume 4: Bedside Handbook concisely presents core elements of the theory and practice of clinical Endobiogeny. It is an essential reference for Endobiogenists and for integrative medicine practitioners looking to expand their practice. Signs, symptoms and biology of function indexes are correlated to each other according to principles of integrative endocrinology and physiology. Over 20 common illnesses are succinctly summarized to be read in under 10 minutes conveying the essence of neuroendocrine causes, mechanisms and effects, followed by prioritization of Endobiogenic treatments based on 40+ years of clinical experience. Finally, for exemplary prescriptions, alternate plants are proposed based on the context of the specific illness. A succinct materia medica summarizes the essence and key role of nearly 80 medicinal plants used in clinical Endobiogeny, offering new insights for experienced prescribers and clear guidance for those new to the usage of medicinal plants. The Theory of Endobiogeny Volume 4 provides clinicians and researchers with a concise handbook covering the application of Endobiogeny in current clinical practice.

  • Semi-empirical Neural Network Modeling and Digital Twins Development

    • 1st Edition
    • Dmitriy Tarkhov + 1 more
    • English
    Semi-empirical Neural Network Modeling presents a new approach on how to quickly construct an accurate, multilayered neural network solution of differential equations. Current neural network methods have significant disadvantages, including a lengthy learning process and single-layered neural networks built on the finite element method (FEM). The strength of the new method presented in this book is the automatic inclusion of task parameters in the final solution formula, which eliminates the need for repeated problem-solving. This is especially important for constructing individual models with unique features. The book illustrates key concepts through a large number of specific problems, both hypothetical models and practical interest.

  • The Zebrafish in Biomedical Research

    Biology, Husbandry, Diseases, and Research Applications
    • 1st Edition
    • Samuel Cartner + 5 more
    • English
    The Zebrafish in Biomedical Research: Biology, Husbandry, Diseases, and Research Applications is a comprehensive work that fulfills a critical need for a thorough compilation of information on this species. The text provides significant updates for working vivarium professionals maintaining zebrafish colonies, veterinarians responsible for their care and well-being, zoologists and ethologists studying the species, and investigators using the species to gain critical insights into human physiology and disease. As the zebrafish has become an important model organism for the study of vertebrate development and disease, organ function, behavior, toxicology, cancer, and drug discovery, this book presents an important resource for future research.

  • Medical Semiology Guide of the Cardiovascular System and the Hematologic System

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology Guide of the Cardiovascular System and the Hematologic System provides a comprehensive understanding of medical semiology in the cardiovascular and hematologic systems. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference for clinicians.

  • Immunobiology of Dendritic Cells Part B

    • 1st Edition
    • Volume 349
    • English
    Immunobiology of Dendritic Cells Part B, Volume 349 in the International Review of Cell and Molecular Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Global Change and Forest Soils

    Cultivating Stewardship of a Finite Natural Resource
    • 1st Edition
    • Volume 36
    • English
    Global Change and Forest Soils: Cultivating Stewardship of a Finite Natural Resource, Volume 36, provides a state-of-the-science summary and synthesis of global forest soils that identifies concerns, issues and opportunities for soil adaptation and mitigation as external pressures from global changes arise. Where, how and why some soils are resilient to global change while others are at risk is explored, as are upcoming train wrecks and success stories across boreal, temperate, and tropical forests. Each chapter offers multiple sections written by leading soil scientists who comment on wildfires, climate change and forest harvesting effects, while also introducing examples of current global issues. Readers will find this book to be an integrated, up-to-date assessment on global forest soils.

  • Sugarcane Biorefinery, Technology and Perspectives

    • 1st Edition
    • Fernando Santos + 3 more
    • English
    Sugarcane Biorefinery, Technology and Perspectives provides the reader with a current view of the global scenario of sugarcane biorefinery, launching a new expectation on this important crop from a chemical, energy and sustainability point-of-view. The book explores the existing biorefinery platforms that can be used to convert sugarcane to new high value added products. It also addresses one of today's most controversial issues involving energy cane, in addition to the dilemma "sugar cane vs. food vs. the environment", adding even more value in a culture that is already a symbol of case study around the world. Focusing on the chemical composition of sugarcane, and the production and processes that optimize it for either agricultural or energy use, the book is designed to provide practical insights for current application and inspire the further exploration of options for balancing food and fuel demands.

  • Medical Semiology Guide of the Renal System

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology Guide of the Renal System provides a comprehensive understanding of medical semiology in the renal system. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers in the field. Each chapter incorporates a specific questionnaire with important questions that should be asked to patients in different situations to obtain valuable information that helps identify rare and unusual diseases. This unique feature of the book aims to facilitate the learning process among medical students, while also acting as a quick reference guide for clinicians in practice.

  • Advances in Insect Physiology

    • 1st Edition
    • Volume 57
    • English
    Advances in Insect Physiology, Volume 57, provides readers with the latest interdisciplinary reviews on the topic. It is an essential reference source for invertebrate physiologists, neurobiologists, entomologists, zoologists and insect chemists, with this new release focusing on the Ecology and evolution of social insect cognition, Fly foregut and transmission of microbes, and Hormonal regulation of insect feeding behaviors, among other topics.

  • Medical Semiology Guide of the Respiratory System

    • 1st Edition
    • Manuela Stoicescu
    • English
    Medical Semiology Guide of the Respiratory System provides a comprehensive understanding of medical semiology to facilitate the learning process and stimulate medical thinking in respiratory medicine. Highly illustrated, with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter incorporates a specific questionnaire with important questions that need to be addressed in different situations to obtain valuable information to help in medical thinking and in the formulation of a diagnosis.

  • Computational Learning Approaches to Data Analytics in Biomedical Applications

    • 1st Edition
    • Khalid Al-Jabery + 3 more
    • English
    Computational Learning Approaches to Data Analytics in Biomedical Applications provides a unified framework for biomedical data analysis using varied machine learning and statistical techniques. It presents insights on biomedical data processing, innovative clustering algorithms and techniques, and connections between statistical analysis and clustering. The book introduces and discusses the major problems relating to data analytics, provides a review of influential and state-of-the-art learning algorithms for biomedical applications, reviews cluster validity indices and how to select the appropriate index, and includes an overview of statistical methods that can be applied to increase confidence in the clustering framework and analysis of the results obtained.

  • Encyclopedia of Biomedical Gerontology

    • 1st Edition
    • Suresh Rattan
    • English
    Encyclopedia of Biomedical Gerontology, Three Volume Set presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention.

  • Sustainable Agriculture

    Advances in Plant Metabolome and Microbiome
    • 1st Edition
    • Javid Ahmad Parray + 1 more
    • English
    Sustainable Agriculture: Advances in Plant Metabolome and Microbiome focuses on the advancement of basic and applied research related to plant-microbe interaction and their implementation in progressive agricultural sustainability. The book also highlights the developing area of bioinformatics tools for the interpretation of metabolome, the integration of statistical and bioinformatics tools to manage huge generating data, metabolite profiling, and key signaling-driven substances, along with a section on the role of key biosynthetic pathways. Focused on selecting positive and effective interactive core-microbiome which will be adaptive and sustainable, this book will help researchers further improve the quality and productivity of crops through sustainable agriculture.

  • Horticultural Plant Breeding

    • 1st Edition
    • Thomas J. Orton
    • English
    Horticultural Plant Breeding is a complete and comprehensive resource for the development of new cultivars or clones of horticultural crops. It covers the basic theories that underpin plant breeding and applies Mendelian, quantitative and population inheritance practices in smaller populations where the individual plant has high value. Specific traditional breeding methods are also covered, with an emphasis on how these methods are adapted for horticultural species. In addition, the integration of biotechnologies with traditional breeding methodologies is explored, with an emphasis on specific applications for fruits, vegetables and ornamental crop species. Presented in focused sections, Horticultural Plant Breeding addresses historical perspectives and context, and genetics as a critical foundation of plant breeding. It highlights treatments of the various components of breeding programs, such as breeding objectives, germplasm, population engineering, mating systems, enhanced selection methods, established breeding methods applicable to inbreeding and outcrossing situations, and post-breeding activities.

  • Abscisic Acid in Plants

    • 1st Edition
    • Volume 92
    • English
    Abscisic Acid in Plants, Volume 92, the latest release in the Advances in Botanical Research series, is a compilation of the current state-of-the-art on the topic. Chapters in this new release comprehensively describe latest knowledge on how ABA functions as a plant hormone. They cover topics related to molecular mechanisms as well as the biochemical and chemical aspects of ABA action: hormone biosynthesis, catabolism, transport, perception, signaling in plants, seeds and in response to biotic and abiotic stresses, hormone evolution and chemical biology, and much more.

  • Geriatric Neurology

    • 1st Edition
    • Volume 167
    • English
    Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information necessary to aid in diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians on how to understand and treat common neurological disorders in the elderly.

  • Conceptual Breakthroughs in Evolutionary Ecology

    • 1st Edition
    • Laurence Mueller
    • English
    Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution.

  • General Medical Semiology Guide Part II

    • 1st Edition
    • Manuela Stoicescu
    • English
    General Medical Semiology Guide, Part Two is the second volume in a two volume set that provides a comprehensive understanding of medical semiology. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter contains a specific questionnaire of important questions that should be asked of patients in different situations to obtain valuable information that will assist in both medical thinking and in the formulation of diagnoses. Part Two covers topics on how to examine primary and secondary skin lesions, hair changes, nails, lymph nodes, breasts, and more.

  • Perspectives in the Development of Mobile Medical Information Systems

    Life Cycle, Management, Methodological Approach and Application
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Perspectives in the Development of Mobile Medical Information Systems: Life Cycle, Management, Methodological Approach and Application discusses System Development Life Cycle (SDLC) thoroughly, focusing on Mobile Healthcare Information Systems (M-HIS). Covering all aspect of M-HIS development, the book moves from modeling, assessment, and design phases towards prototype phase. Topics such as mobile healthcare information system requirements, model identification, user behavior, system analysis and design are all discussed. Additionally, it covers the construction, coding and testing of a new system, and encompasses a discussion on future directions of the field. Based on an existing mobile cardiac emergency system used as a real case throughout the chapters, and unifying and clarifying the various processes and concepts of SDLC for M-HIS, this book is a valuable source for medical informaticians, graduate students and several members of biomedical and medical fields interested in medical information systems.

  • Demystifying the Engineering PhD

    • 1st Edition
    • Monica Cox
    • English
    Demystifying the Engineering Ph.D. explores what it means to be an engineering Ph.D. holder, including insights from engineering professionals working in academia and industry across multiple institute types and companies. Topics covered include motivations for obtaining a Ph.D., the added value of a Ph.D., and career options for Ph.D. holders. The book concludes with recommendations for transforming engineering doctoral education to preparing doctoral students for diverse careers in industry and academia.

  • Wearable Robotics

    Systems and Applications
    • 1st Edition
    • Jacob Rosen
    • English
    Wearable Robotics: Systems and Applications provides a comprehensive overview of the entire field of wearable robotics, including active orthotics (exoskeleton) and active prosthetics for the upper and lower limb and full body. In its two major sections, wearable robotics systems are described from both engineering perspectives and their application in medicine and industry. Systems and applications at various levels of the development cycle are presented, including those that are still under active research and development, systems that are under preliminary or full clinical trials, and those in commercialized products. This book is a great resource for anyone working in this field, including researchers, industry professionals and those who want to use it as a teaching mechanism.

  • Precision Medicine for Investigators, Practitioners and Providers

    • 1st Edition
    • Joel Faintuch + 1 more
    • English
    Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included.

  • General Medical Semiology Guide Part I

    • 1st Edition
    • Manuela Stoicescu
    • English
    General Medical Semiology Guide, Part One is the first part of a two volume set that provides a comprehensive understanding of medical semiology. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter contains a specific questionnaire of important questions that should be asked of patients in different situations to obtain valuable information that will assist in both medical thinking and in the formulation of diagnoses. This volume covers the face, eyes, thyroid gland, skin, mucoses, and more.

  • Innate Immunity

    From Louis Pasteur to Jules Hoffmann
    • 1st Edition
    • Yves Carton
    • English
    Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011.

  • A Physicochemical Theory of Tip Growth

    • 1st Edition
    • Pierre Pelce
    • English
    A Physicochemical Theory of Tip Growth presents the latest information on experimental observations on living organisms, including unicellular algae, hyphae and neurons. These theories are analogous to the ones developed for the growth of nonliving matter, as already exposed by the author in the book.

  • Milk Proteins

    From Expression to Food
    • 3rd Edition
    • Mike Boland + 1 more
    • English
    Milk Proteins: From Expression to Food, Third Edition contains contributions from internationally recognized authors from academia and industry. Professionals, academics and graduate students working in any of the dairy-related industries or disciplines will continue to find this updated information valuable to their work. Using a unique "field-to-table" approach, this third edition provides comprehensive coverage of new developments and insights into the entire dairy food chain – from the source, to the nutritional aspects affecting the customer. Containing three new chapters, this new edition continues to present a comprehensive overview of the biology, processing, chemistry, and nutrition of milk proteins and features the latest science and developments. Valuable application-based information is made available through the exploration of the use of milk proteins from industry viewpoints.

  • Clinical Precision Medicine

    A Primer
    • 1st Edition
    • Judy S. Crabtree
    • English
    Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine.

  • Machine Learning

    Methods and Applications to Brain Disorders
    • 1st Edition
    • Andrea Mechelli + 1 more
    • English
    Machine Learning is an area of artificial intelligence involving the development of algorithms to discover trends and patterns in existing data; this information can then be used to make predictions on new data. A growing number of researchers and clinicians are using machine learning methods to develop and validate tools for assisting the diagnosis and treatment of patients with brain disorders. Machine Learning: Methods and Applications to Brain Disorders provides an up-to-date overview of how these methods can be applied to brain disorders, including both psychiatric and neurological disease. This book is written for a non-technical audience, such as neuroscientists, psychologists, psychiatrists, neurologists and health care practitioners.

  • Cingulate Cortex

    • 1st Edition
    • Volume 166
    • English
    Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same.

  • Late Aging Associated Changes in Alcohol Sensitivity, Neurobehavioral Function, and Neuroinflammation

    • 1st Edition
    • Volume 148
    • English
    Late aging associated changes in alcohol sensitivity, neurobehavioral function, and neuroinflammation, Volume 148, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

  • Engineering Strategies for Regenerative Medicine

    • 1st Edition
    • Tiago G. Fernandes + 2 more
    • English
    Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.

  • Applied Genomics and Public Health

    • 1st Edition
    • George P. Patrinos
    • English
    Applied Genomics and Public Health examines the interdisciplinary and growing area of how evidence-based genomic knowledge can be applied to public health, population health, healthcare and health policies. The book gathers experts from a variety of disciplines, including life sciences, social sciences, and health care to develop a comprehensive overview of the field. In addition, the book delves into subjects such as pharmacogenomics, genethics, big data, data translation and analysis, economic evaluation, genomic awareness and education, sociology, pricing and reimbursement, policy measures and economic evaluation in genomic medicine. This book is essential reading for researchers and students exploring applications of genomics to population and public health. In addition, it is ideal for those in the biomedical sciences, medical sociologists, healthcare professionals, nurses, regulatory bodies and health economists interested in learning more about this growing field.

  • Handbook of Data Science Approaches for Biomedical Engineering

    • 1st Edition
    • Valentina Emilia Balas + 3 more
    • English
    Handbook of Data Science Approaches for Biomedical Engineering covers the research issues and concepts of biomedical engineering progress and the ways they are aligning with the latest technologies in IoT and big data. In addition, the book includes various real-time/offline medical applications that directly or indirectly rely on medical and information technology. Case studies in the field of medical science, i.e., biomedical engineering, computer science, information security, and interdisciplinary tools, along with modern tools and the technologies used are also included to enhance understanding. Today, the role of Big Data and IoT proves that ninety percent of data currently available has been generated in the last couple of years, with rapid increases happening every day. The reason for this growth is increasing in communication through electronic devices, sensors, web logs, global positioning system (GPS) data, mobile data, IoT, etc.

  • Tumor Immunology and Immunotherapy – Molecular Methods

    • 1st Edition
    • Volume 629
    • English
    Tumor Immunology and Immunotherapy – Molecular Methods, Volume 629, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this release include Droplet digital PCR for measuring circulating tumor-derived DNA, Detection and quantification of cytosolic DNA, Methods to detect endogenous dsRNA induction and recognition, Quantification of eIF2alpha phosphorylation during immunogenic cell death, Assessment of annexin A1 release during immunogenic cell death, Luciferase-assisted detection of extracellular ATP in the course of ICD, The P2X7 receptor: structure and function, and much more.

  • The Craft Brewing Handbook

    A Practical Guide to Running a Successful Craft Brewery
    • 1st Edition
    • Chris Smart
    • English
    The Craft Brewing Handbook: A Practical Guide to Running a Successful Craft Brewery covers the practical and technical aspects required to set up and grow a successful craft brewing business. With coverage of equipment options, raw material choice, the brewing process, recipe development and beer styles, packaging, quality assurance and quality control, sensory evaluation, common faults in beer, basic analyses, and strategies to minimize utilities, such as water and energy, this book is a one-stop shop for the aspiring brewer. The craft brewing sector has grown significantly around the world over the past decade. Many new breweries are technically naïve and have a thirst for knowledge. This book not only covers how to maximize the chances of getting production right the first time, it also deals with the inevitable problems that arise and what to do about them.

  • Chick Chorioallantoic Membrane Model and Precision Cancer Therapy

    • 1st Edition
    • Volume 46
    • Fuyuhiko Tamanoi
    • English
    Chick Chorioallantoic Membrane Model and Precision Cancer Therapy, Volume 46 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on the history of CAM model development, an overview of various CAM-based cancer models, the chick embryo chorioallantoic membrane as an in vivo experimental model to study multiple myelomak, bioluminescent CAM models for screening drugs against pancreatic cancer, X-ray sensitizer screen, patient derived tumor model for esophageal cancer, renal cancer and metastasis, nanoparticle characterization and tumor targeting, and patient derived tumor model for human nasopharyngeal carcinoma.

  • Psychopharmacology of Neurologic Disease

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 165
    • English
    Psychopharmacology of Neurologic Disease, Volume 165 in the Handbook of Clinical Neurology series, provides clinicians with an up-to-date, critical review of the best approaches to treatment of neurologic disease as discussed by experienced clinical investigators. The book is organized into sections on dementia, delirium, movement disorders, hereditary degenerative disease, epilepsy and psychogenic seizures, brain vascular disease, pseudobulbar affect, traumatic brain injury, neuro-oncology, multiple sclerosis and other demyelinating disorders, chronic fatigue syndrome/fibromyalgi... pain, headache, sleep disorders, autoimmune encephalitis/anti- NMDA encephalitis, functional sensory neurologic symptom disorders and neurodevelopmental disorders. Each of these diagnostic categories has a significant incidence of behavioral symptomatology that is secondary to the neurologic diagnosis that can serve to complicate other therapeutic interventions, alter the course of illness, and cause distress in patients and family caregivers.

  • Inquiry, Treatment Principles, and Plans in Integrative Cardiovascular Chinese Medicine

    Volume 5
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Inquiry, Treatment Principles and Plans in Integrative Cardiovascular Chinese Medicine, volume five in the Integrative Cardiovascular Chinese Medicine series, provides the benefits of using the intake form, patient narratives and proper inquiry based on Chinese and Western medicine methods within the clinical setting to establish reliable treatment plans for cardiovascular patients. This reference is organized systematically into three sections covering questionnaires and testimony from patients, inquiry and physical examination techniques that are useful for examining cardiac patients, and specific cardiovascular symptoms in the new and returning patient, including definition of the symptom and clinical significance from Chinese and Western perspectives and treatment principles. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.

  • The Role of Ecosystem Services in Sustainable Food Systems

    • 1st Edition
    • Leonard Rusinamhodzi
    • English
    The Role of Ecosystem Services in Sustainable Food Systems reveals, in simple terms, the operational definition, concepts and applications of ecosystem services with a focus on sustainable food systems. The book presents case studies on both geographical and production system-wide considerations. Initial chapters discuss concepts, methodologies and the tools needed to understand ecosystem services in the broader food system. Middle and later chapters present different perspectives from case studies of ecosystem services derived from some of the key sustainable food production systems used by farmers, along with discussions on the challenges of deriving full benefits and how they can be overcome. Researchers, students, scientists, development practitioners and policymakers will welcome this reference as they continue their work related to sustainable food systems.

  • The Laboratory Rat

    • 3rd Edition
    • Mark A. Suckow + 3 more
    • English
    The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.

  • Plant Systematics

    • 3rd Edition
    • Michael G. Simpson
    • English
    Plant Systematics, Third Edition, has made substantial contributions to plant systematics courses at the upper-undergraduate and first year graduate level, with the first edition winning The New York Botanical Garden's Henry Allan Gleason Award for outstanding recent publication in plant taxonomy, plant ecology or plant geography. This third edition continues to provide the basis for teaching an introduction to the morphology, evolution and classification of land plants. A foundation of the approach, methods, research goals, evidence and terminology of plant systematics are presented, along with the most recent knowledge of evolutionary relationships of plants and practical information vital to the field. In this new edition, the author includes greatly expanded treatments on families of flowering plants, as well as tropical trees (all with full-color plates), and an updated explanation of maximum likelihood and Bayesian inference algorithms. Chapters on morphology and plant nomenclature have also been enhanced with new material.

  • Insect Collection and Identification

    Techniques for the Field and Laboratory
    • 2nd Edition
    • Timothy J. Gibb + 1 more
    • English
    Insect Collection and Identification: Techniques for the Field and Laboratory, Second Edition, is the definitive text on all aspects required for collecting and properly preparing specimens for identification. This book provides detailed taxonomic keys to insects and related arthropods, giving recent classification changes to various insect taxa, along with updated preservation materials and techniques for molecular and genomic studies. It includes methods of rearing, storing and shipping specimens, along with a supporting glossary. New sections provide suggestions on how insects and other arthropods can be used within, and outside, the formal classroom and examine currently accepted procedures for collecting insects at crime scenes. This book is a necessary reference for entomology professionals and researchers who seek the most updated taxonomy and techniques for collection and preservation. It will serve as a valuable resource for entomology students and professionals who need illustrative and detailed information for easy arthropod identification.

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