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Books in Life sciences

Inhibitors of the Ras Superfamily G-proteins, Part B
1st Edition
Volume 34
English
Targeted toward researchers in biochemistry, molecular and cell biology, pharmacology, and cancer, this is the second part of The Enzymes' volumes that discuss inhibitors of the Ras superfamily G-proteins.
The Squirrel Monkey
1st Edition
Leonard A. Rosenblum + 1 more
English
The Squirrel Monkey is devoted to the common South American squirrel monkey, Saimiri sciureus. In light of the growing number of squirrel monkeys being established each year in many laboratories, there appeared the need to pool existing knowledge in concise form. The present volume, the first of its kind on any single primate, attempts to meet this need. The topics that have been selected cover thoroughly areas of research in which Saimiri has been utilized. This material ranges widely from taxonomy and behavioral studies through husbandry and clinical management of the species, to investigations in aerospace medicine and in a number of basic biological sciences. Since the problems encountered in the squirrel monkey, though sometimes taking a particular form, are not unique in principle, the authors have attempted to provide an appropriate phylogenetic context for their material. It is hoped as a result that this compendium may serve as a valuable source of information during various phases of work on other subjects of primatological and comparative biological investigation as well.
Microbial Synthetic Biology
1st Edition
Volume 40
English
The 40th volume of Methods in Microbiology focuses on microbial synthetic biology.Synthetic biology is a rapidly growing discipline that builds on well-established principles of genetic engineering and biotechnology by integrating computational and engineering approaches to the design and construction of novel biological systems.This volume addresses some of the major technical challenges stand in the way of achieving a radical step-change in our ability to engineer complex multi-scaled biological systems. These include: the application of computation intelligence to the design of synthetic microbial systems, design automation and constraints; the impact of noise and stochasticity; the engineering of biosensors; the characteristic of a model bacterial chassis. A key issue in Synthetic Biology is that of its social dimensions and a chapter is dedicated to the important issue.
The Beginnings of Electron Microscopy
1st Edition
Peter W. Hawkes
English
The Beginnings of Electron Microscopy presents the technical development of electron microscope. This book examines the mechanical as well as the technical problems arising from the physical properties of the electron. Organized into 19 chapters, this book begins with an overview of the history of scanning electron microscopy and electron beam microanalysis. This text then explains the applications and capabilities of electron microscopes during the war. Other chapters consider the classical techniques of light microscopy. This book presents as well the schematic outline of the preparation techniques for investigation of nerve cells by electron microscopy. The final chapter deals with the historical account of the beginnings of electron microscopy in Russia. This book is a valuable resource for scientists, technologists, physicists, electrical engineers, designers, and technicians. Graduate students as well as researcher workers who are interested in the history of electron microscopy will also find this book extremely useful.
Aspects of Cell Regulation
1st Edition
G. H. Bourne + 1 more
English
Aspects of Cell Regulation deals with the various aspects of cellular control mechanisms. The book begins with a discussion of the role of hormones in the control of cell differentiation and biochemical control over the life of an organism. This is followed by separate chapters on an intracellular control problem, namely, the proper reproduction of cellular organelles and their apportionment between daughter cells at cell mitosis; cell mutants with different temporal order for macromolecular synthesis; and the control of a plant enzyme that converts triglycerides into carbohydrate during the early stages of postgerminative growth within seed cotyledon. Subsequent chapters deal with the possible role of mitochondria in changing the control mechanism of cells to that associated with carcinogenesis; the possibility of transforming genes being detectable in the genome after the transformation to neoplastic cell; the correlation between viruses and tumor cells; and whether viruses can originate from cells rather than coming before cells.
Computer Techniques for Image Processing in Electron Microscopy
1st Edition
W. O. Saxton
L. Marton + 1 more
English
Computer Techniques for Image Processing in Electron Microscopy: Advances in Electronics and Electron Physics presents the sophisticated computer generated in processing the image. This book discusses the development of fast Fourier transform algorithms, which has led to the possibility of achieving a more reliable interpretation of electron micrographs by digital means. Organized into 10 chapters, this book begins with an overview of image formation in which the properties of the linear approximation are included. This text then reviews the available hardware and the basic mathematical methods of image processing in electron microscopy. Other chapters consider the constraints imposed on the image wave function by the objective lens aperture. This book discusses as well the properties of discrete Fourier transforms. The final chapter deals with a particular processing system called the Improc system. This book is a valuable resource for physicists and researcher workers who are interested in the study of image processing.
Circadian Rhythms and the Human
1st Edition
D. S. Minors + 1 more
English
Circadian Rhythms and the Human covers the basic principles behind the human circadian rhythms. This book is composed of 12 chapters that discuss the detection, analysis, and definition of rhythms, specifically exogenous and endogenous rhythms. This book also demonstrates the mechanism of metabolic and gastrointestinal rhythms. The opening chapters deal with the rhythms in living organism; establishing the endogeneity of rhythms; definition of nychthemeral rhythm; methods of measuring the frequency of rhythms; exogenous effects upon the temperature rhythm; interaction between exogenous and endogenous influences; and possible origins of renal rhythmicity. The succeeding chapters consider the effect of exercise at different times of day and the concept of sleep-wakefulness rhythm. The discussion then shifts to the effects of repeated time-zone transitions and the effects of time on drug administration. The closing chapters are devoted to the assessment of work performance during shift work. The book can provide useful information to doctors, students, researchers, and the general reader.
Bio-nanoimaging
Protein Misfolding and Aggregation
1st Edition
Vladimir N Uversky + 1 more
English
Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering:- Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobuli... studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers- Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties.
Functional Organization of Vertebrate Plasma Membrane
1st Edition
Volume 72
English
Current Topics in Membranes is targeted toward scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. This volume covers recent breakthroughs in understanding the molecular and cellular basis for patterning vertebrate plasma membranes. A special emphasis is placed on physiological function with chapters covering signaling in the nervous system and heart, vision, and the immune system.
Diffusion MRI
From Quantitative Measurement to In vivo Neuroanatomy
2nd Edition
Heidi Johansen-Berg + 1 more
English
Diffusion MRI remains the most comprehensive reference for understanding this rapidly evolving and powerful technology and is an essential handbook for designing, analyzing, and interpreting diffusion MR experiments. Diffusion imaging provides a unique window on human brain anatomy. This non-invasive technique continues to grow in popularity as a way to study brain pathways that could never before be investigated in vivo. This book covers the fundamental theory of diffusion imaging, discusses its most promising applications to basic and clinical neuroscience, and introduces cutting-edge methodological developments that will shape the field in coming years. Written by leading experts in the field, it places the exciting new results emerging from diffusion imaging in the context of classical anatomical techniques to show where diffusion studies might offer unique insights and where potential limitations lie.

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