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Books in Life sciences

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  • Plant Breeding and Cultivar Development

    • 1st Edition
    • D. P. Singh + 2 more
    • English
    Plant Breeding and Cultivar Development features an optimal balance between classical and modern tools and techniques related to plant breeding. Written for a global audience and based on the extensive international experience of the authors, the book features pertinent examples from major and minor world crops. Advanced data analytics (machine learning), phenomics and artificial intelligence are explored in the book's 28 chapters that cover classical and modern plant breeding. By presenting these advancements in specific detail, private and public sector breeding programs will learn about new, effective and efficient implementation. The insights are clear enough that non-plant breeding majoring students will find it useful to learn about the subject, while advanced level students and researchers and practitioners will find practical examples that help them implement their work.

  • Transport Proteins

    • 1st Edition
    • Volume 123
    • English
    Transport Proteins, Volume 123, provides the latest information on the two major groups of transport proteins, those that carry molecules to different locations within a cell or organism and those that carry molecules across otherwise impermeable membranes. Chapters in the updated release include Biology of Iron Transport: Ferroportin, Transport of transition metals across biological membranes, The effect of sport and physical activity on transport proteins: implications for cancer prevention and control, Structural rearrangement in polyketide synthase for improvement its bio-physicochemical properties, Autophagy Proteins and its Homeostasis in Cellular Environment, and much more.

  • The Design and Development of Novel Drugs and Vaccines

    Principles and Protocols
    • 1st Edition
    • Tarun Kumar Bhatt + 1 more
    • English
    The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval.

  • Stem Cells

    Scientific Facts and Fiction
    • 3rd Edition
    • Christine L. Mummery + 3 more
    • English
    Stem Cells: Scientific Facts and Fiction, Third Edition, provides a state-of-the-art overview on the field of stem cells and their current applications. The book incorporates the history and firsthand commentaries in the field from clinical and research leaders, covering interesting topics of note, including the first clinical trials to treat Parkinson disease, macular degeneration, and corneal replacement, the cloning of monkeys, the organoid field, and CRISPR-edited genomics. In addition, coverage of adult, embryonic stem cells and iPS cells is included. This new edition distinguishes itself from the multiplicity of websites about stem cells with a broad view of the field.

  • Linkers in Biomacromolecules

    • 1st Edition
    • Volume 647
    • English
    Linkers in Biomacromolecules, Volume 647 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this updated release include chapters devoted to ser-gly linkers + models, sergGly- EAAAK linkers, Effect of crowding on linker behavior, Protathether. Experimental approach to quickly test different linkers in fusion proteins, Linkers in enzyme fusions/cascade catalysis, Linker dependence of avidity in multivalent interactions between disordered proteins, ER/K α-helix linker, The effect of chirality and steric hindrance on intrinsic backbone conformational propensities: tools for protein design, Linker design in protein-based nanostructures, and much more. Linkers in Biomacromolecules, Volume 647 in the Methods in Enzymology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this updated release include chapters devoted to ser-gly linkers + models, sergGly- EAAAK linkers, Effect of crowding on linker behavior, Protathether. Experimental approach to quickly test different linkers in fusion proteins, Linkers in enzyme fusions/cascade catalysis, Linker dependence of avidity in multivalent interactions between disordered proteins, ER/K α-helix linker, The effect of chirality and steric hindrance on intrinsic backbone conformational propensities: tools for protein design, Linker design in protein-based nanostructures, and much more.

  • Endothelial Signaling in Vascular Dysfunction and Disease

    From Bench to Bedside
    • 1st Edition
    • Shampa Chatterjee
    • English
    Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease.

  • Food Technology Disruptions

    • 1st Edition
    • Charis M. Galanakis
    • English
    Food Technology Disruptions covers the latest disruptions in the food industry, such as the Internet of Things, digital technologies, modern applications like 3D printing, bacterial sensors in food packaging, electronic noses for food authentication, and artificial intelligence. With additional discussions on innovative distribution and delivery of food and consumer acceptance of food disruptions, this book is an essential resource for food scientists, technologists, engineers, agriculturalists, chemists, product developers, researchers, academics and professionals working in the food industry. While innovations play an important role in food production, disruptive technologies are a revolutionary type of innovation that can displace an established technology and shake up the industry...or create a completely new industry. Currently, digital technologies and smart applications lead innovations in the food sector in order to optimize the food supply chain and to develop and deliver tailor-made food products to consumers with new eating habits.

  • Plant Biochemistry

    • 5th Edition
    • Hans-Walter Heldt + 1 more
    • English
    Plant Biochemistry, Fifth Edition, enables students to gain basic knowledge of the entire field, from photosynthesis to genetic engineering and its many commercial applications. Topics include cell structure and function of isoprenoids, phenylpropanoids and other secondary metabolites, and plant growth regulation and development. The text covers recent research findings and identifies areas of future research. This book is suitable for graduate students and advanced undergraduates in plant physiology, plant pathology, plant cell biology, and other plant sciences, researchers in industries actively involved in agribusiness, other biotechnology enterprises, and researchers in agronomy, agriculture, plant development and related areas.

  • Himalayan Medicinal Plants

    Advances in Botany, Production & Research
    • 1st Edition
    • Nikhil Malhotra + 1 more
    • English
    The Himalayan Region is a mega hot spot for biological diversity. It supports over 1,748 plants species of known medicinal value. This title focuses on origin and distribution of Himalayan herbs, their medicinal potential, industrial significance, and research advancements pertaining to molecular breeding and omics-based approaches.

  • Inhaled Medicines

    Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches
    • 1st Edition
    • Stavros Kassinos + 3 more
    • English
    Inhaled medicines are widely used to treat pulmonary and systemic diseases. The efficacy and safety of these medicines can be influenced by the deposited fraction, the regional deposition pattern within the lungs and by post-depositional events such as drug dissolution, absorption and clearance from the lungs. Optimizing performance of treatments thus requires that we understand and are able to quantify these product and drug attributes. Inhaled Medicines: Optimizing Development through Integration of In Silico, In Vitro and In Vivo Approaches explores the current state of the art with respect to inhalation drug delivery, technologies available to assess product performance, and novel in silico methods now available to link in vitro product performance to clinical performance. Recent developments in the latter field, especially the prospect of integration of three-dimensional Computational Fluid Particle Methods (3D-CFPD) with physiologically based pharmacokinetic (PBPK models), unlocks the potential for in silico population studies that can help inform and optimize treatment and product development strategies. In this highly multidisciplinary field, where progress occurs at the intersection of several disciplines of engineering and science, this work aims to integrate current knowledge and understanding and to articulate a clear vision for future developments.

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