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    • New Targeting in The Reversal of Resistant Glioblastomas

      • 1st Edition
      • Volume 14
      • March 5, 2021
      • Ali Syed Arbab
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 5 2 7 1
      • eBook
        9 7 8 0 1 2 8 2 3 2 7 6 7
      New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field.

    • Research and Clinical Applications of Targeting Gastric Neoplasms

      • 1st Edition
      • July 17, 2021
      • Brendan Jenkins
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 5 6 3 1
      • eBook
        9 7 8 0 3 2 3 8 8 5 5 4 6
      Research and Clinical Applications of Targeting Gastric Neoplasms provides a comprehensive overview of gastrointestinal cancers, covering preclinical research and clinical findings related to risk factors, current treatment regimens (including immunotherapy), screening/detection methods, etiology of disease, precision medicine and future perspectives. Gastrointestinal cancers rank among the most lethal and common worldwide, and as such, there is intense research into their diverse causes and treatment options. This reference provides a consolidation of the research, making it a perfect resource for basic science and clinical researchers as well as oncologists who work in gastroenterology and GI tract cancer fields.

    • Biological Macromolecules

      • 1st Edition
      • November 18, 2021
      • Amit Kumar Nayak + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 7 5 9 8
      • eBook
        9 7 8 0 3 2 3 8 5 6 3 8 6
      Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine.

    • Microbiome Stimulants for Crops

      • 1st Edition
      • April 17, 2021
      • James F. White + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 1 2 2 8
      • eBook
        9 7 8 0 1 2 8 2 2 1 6 0 0
      Microbiome Stimulants for Crops: Mechanisms and Applications provides the latest developments in the real-world development and application of these crop management alternatives in a cost-effective, yield protective way. Sections address questions of research, development and application, with insights into recent legislative efforts in Europe and the United States. The book includes valuable information regarding mechanisms and the practical information needed to support the growing microbial inoculant and biostimulant industry, thus helping focus scientific research in new directions.

    • New Paradigms in Computational Modeling and Its Applications

      • 1st Edition
      • January 9, 2021
      • Snehashish Chakraverty
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 1 3 3 4
      • eBook
        9 7 8 0 1 2 8 2 2 1 6 8 6
      In general, every problem of science and engineering is governed by mathematical models. There is often a need to model, solve and interpret the problems one encounters in the world of practical problems. Models of practical application problems usually need to be handled by efficient computational models. New Paradigms in Computational Modeling and Its Applications deals with recent developments in mathematical methods, including theoretical models as well as applied science and engineering. The book focuses on subjects that can benefit from mathematical methods with concepts of simulation, waves, dynamics, uncertainty, machine intelligence, and applied mathematics. The authors bring together leading-edge research on mathematics combining various fields of science and engineering. This perspective acknowledges the inherent characteristic of current research on mathematics operating in parallel over different subject fields. New Paradigms in Computational Modeling and Its Applications meets the present and future needs for the interaction between various science and technology/engineeri... areas on the one hand and different branches of mathematics on the other. As such, the book contains 13 chapters covering various aspects of computational modeling from theoretical to application problems. The first six chapters address various problems of structural and fluid dynamics. The next four chapters include solving problems where the governing parameters are uncertain regarding fuzzy, interval, and affine. The final three chapters will be devoted to the use of machine intelligence in artificial neural networks.

    • Recent Advances in iPSCs for Therapy

      • 1st Edition
      • January 30, 2021
      • Alexander Birbrair
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 2 9 4
      • eBook
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      The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSCs for Therapy, Volume 3 addresses the use of induced pluripotent stem cells for therapy of several disorders. The volume teaches the reader about the biology of induced pluripotent stem cells and their possible use as cell therapy. Remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs for therapy of multiple diseases, such as: hair loss disorders, Parkinson’s disease, Huntington’s disease, ischemic stroke, Alzheimer’s disease, Glaucoma, Optic Neuropathy, Age-Related Macular Degeneration, Type 1 Diabetes, Heart Failure, liver diseases, infertility, Autoimmune Diseases, and more. The volume is written for researchers and scientists interested in cell therapy, stem cell biology, regenerative medicine, and organ transplantation and is contributed by world-renowned authors in the field.

    • Epigenetics in Cardiovascular Disease

      • 1st Edition
      • Volume 24
      • March 6, 2021
      • Yvan Devaux + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 5 8 4
      • eBook
        9 7 8 0 1 2 8 2 2 2 5 9 1
      Epigenetics in Cardiovascular Disease, a new volume in the Translational Epigenetics series, offers a comprehensive overview of the epigenetics mechanisms governing cardiovascular disease development, as well as instructions in research methods and guidance in pursing new studies. More than thirty international experts provide an (i) overview of the epigenetics mechanisms and their contribution to cardiovascular disease development, (i) high-throughput methods for RNA profiling including single-cell RNA-seq, (iii) the role of nucleic acid methylation in cardiovascular disease development, (iv) epigenetic actors as biomarkers and drug targets, (v) and the potential of epigenetics to advance personalized medicine. Here, readers will discover strategies to combat research challenges, improve quality of their epigenetic research and reproducibility of their findings. Additionally, discussion of assay and drug development for personalized healthcare pave the way for a new era of understanding in cardiovascular disease.

    • Plant Nutrition and Food Security in the Era of Climate Change

      • 1st Edition
      • September 19, 2021
      • Vinay Kumar + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 9 1 6 3
      • eBook
        9 7 8 0 1 2 8 2 3 0 9 3 0
      Plant nutrients are the vital elements essential for plant growth and survival, with key roles in adapting to challenging environments. Each nutrient, whether required in relatively large (macronutrients) or minute concentrations (micronutrients) plays a unique role in plant life cycle. Both the insufficient and surplus concentrations of these nutrients may render negative impacts on plant growth and development and therefore their homeostasis is considered critical for optimal plant growth and yield. Plant Nutrition and Food Security in the Era of Climate Change comprehensively reviews all critical plant nutrients. Chapters include topics such as: biological roles, uptake and transport of vital nutrients in plants; an in-depth review of the roles of potassium, calcium, magnesium and trace element; molecular breeding approaches for enhanced plant nutrients; and exploring the rhizosphere microbiome for enhance nutrient availability. Written by leading experts in the field of plant biology, this is an essential read for researchers and scientists interested in plant science, agronomy, food security and environmental science.

    • Managing Healthy Livestock Production and Consumption

      • 1st Edition
      • December 2, 2021
      • Nadia El-Hage Scialabba
      • English
      • Paperback
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      • eBook
        9 7 8 0 1 2 8 2 3 0 5 1 0
      Managing Healthy Livestock Production and Consumption is a highly interdisciplinary resource based on scientific and empirical evidence. It is illustrated with best practices of low-input livestock systems from different continents and offers predictive modelling alternatives for a more resilient future. By addressing gaps of knowledge and presenting scientific perspective studies of livestock’s impact on the environment and the global food supply up to 2050, this book is useful for those advocating for sustainable food systems. Existing evidence of the effects of livestock production on food quality and nutrition is reviewed. Livestock production and consumption is a highly diverse topic where current publications only include/focus a single aspect of the issues, for example, greenhouse gas emissions or health impacts, leading to unilateral decisions such as refraining from meat consumption. However, animals are necessary to soil fertility and ecosystems balance and a more realistic resource is necessary for researchers, scientists, and policy makers. This book clarifies perceptions by presenting sound scientific evidence across livestock landscapes for the scientific community to better appreciate the ecological web of life and the social web of community related to livestock production. An edited work written by globally diverse scientists and practitioners, including field workers, technicians, and policy makers, this is a valuable resource for researchers, teachers, and development agents working in the area of sustainable livestock production and consumption of animal source foods. National, international organizations, policy makers, and donors interested in sustainable development of the livestock sector will also find the information here practical and applicable.

    • Phytochemical Profiling of Commercially Important South African Plants

      • 1st Edition
      • August 28, 2021
      • Alvaro Viljoen + 4 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 3 7 7 9 3
      • eBook
        9 7 8 0 1 2 8 2 3 7 8 0 9
      Phytochemical Profiling of Commercially Important South African Plants comprises a carefully selected group of plant species that are of interest to researchers and industry partners who would like to investigate the commercialization of plant species. The book presents 25 botanicals selected based on commercial relevance. For each of the species, the following topics are covered: botanical description and distribution, phytochemistry (including chemical structures), HPTLC fingerprint analysis, UPLC analysis, and GC analysis (the latter only in the case of essential oil-bearing species). Using standard methodology, high-level chromatographic fingerprints have been developed for better understanding. Different methods are succinctly summarized allowing for the rapid identification of botanical raw materials and formulated consumer products. This book will be extremely valuable to researchers in the field who wish to rapidly identify the constituents and for those who want to prepare formulations of plant material for commercial applications. This work will also be a valuable resource in the field of pharmacognosy.

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