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    • Twentieth Century Mouse Genetics

      • 1st Edition
      • August 26, 2021
      • Robert P. Erickson
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 0 1 6 8
      • eBook
        9 7 8 0 1 2 8 2 4 0 1 7 5
      Twentieth Century Mouse Genetics: A Historical and Scientific Review provides a comprehensive examination of key advances in mouse genetics throughout the 20th century. Here Dr. Robert P. Erickson, a leader in the field, identifies the contributions of historic mouse genetics studies, and how those approaches and early discoveries are still shaping human genetics research and medical genetics today. In addition to historical overviews, the author provides researcher biographies and updates connecting historic research to ongoing advances. Past studies discussed use the T/t complex as an example and include the origins of mouse genetics, the synthesis of genetics and evolution, cytogenetics and gene mapping, population genetics and mutation research, immunogenetics, reproductive genetics, molecular cloning, X-inactivation and epigenetics, sex determination, and pharmacogenetics. Here researchers, students, and clinicians will find fresh inspiration to engage in human genetics research employing mouse models and to translate those findings to clinical practice.

    • Genomics in Biosecurity

      • 1st Edition
      • November 24, 2021
      • Manousos E. Kambouris
      • English
      • Paperback
        9 7 8 0 3 2 3 8 5 2 3 6 4
      • eBook
        9 7 8 0 3 2 3 8 5 2 3 7 1
      Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in definite and practical terms the applicability of genomic technologies in every aspect of biosecurity, from emergent diagnostics to bioterrorism, agroterrorism, next generation biowarfare, biosurveillance and risk assessment. This book offers an integrated discussion of genomics and GCBR (global catastrophic biological risks) events, considering both basic aspects of biosecurity genomics and application of genomic technologies to drive new solutions. Readers will find evidence-based strategies to apply genomics in disease and pathogen monitoring and diagnosis, and more. Social aspects of GCBR events and genomic biosecurity, such as issues of terrorism, policy ethics, and practice, are also considered in-depth.

    • Healthcare Strategies and Planning for Social Inclusion and Development

      • 1st Edition
      • November 9, 2021
      • Basanta Kumara Behera + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 4 4 6 9
      • eBook
        9 7 8 0 3 2 3 9 0 4 1 8 6
      Healthcare Strategies and Planning for Social Inclusion and Development: Volume One: Health for All - Challenges and Opportunities in Healthcare Management examines health care management, particularly in developing countries, along with the key aspects of universal health required to address current global health issues. This new volume begins with an overview of the concept and definition of “Health for All.” The book covers how international organizations like the WHO support national health authorities in managing their core healthcare systems, support healthcare workforces, utilize technologies like health information systems, ensure health coverage and funding, and provide primary healthcare education. This volume is a useful resource to graduate students in public health and health care policy, public health professionals, health and social work researchers, and health policy makers interested in global health and primary healthcare services, particularly in developing countries.

    • Protocol Handbook for Cancer Biology

      • 1st Edition
      • February 12, 2021
      • Gauri Misra + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 0 0 6 5
      • eBook
        9 7 8 0 3 2 3 8 9 8 1 7 1
      Protocol Handbook for Cancer Biology brings together a comprehensive collection of the methods used for cancer assessment, diagnostics, and therapeutics. Various protocols are discussed along with alternative strategies, including the advantages and limitations of techniques that have been used in labs globally. These protocols are presented by cancer biology experts based on their real-world experience. The protocols in this book will be a valuable resource for cancer researchers and graduate students, who can utilize the techniques described to conduct research more efficiently and successfully.

    • Human Biochemistry

      • 2nd Edition
      • November 22, 2021
      • Gerald Litwack
      • English
      • Hardback
        9 7 8 0 3 2 3 8 5 7 1 8 5
      • eBook
        9 7 8 0 3 2 3 9 1 0 5 3 8
      **Selected for Doody’s Core Titles® 2024 in Biochemistry**Human Biochemistry, Second Edition provides a comprehensive, pragmatic introduction to biochemistry as it relates to human development and disease. Here, Gerald Litwack, award-wining researcher and longtime teacher, discusses the biochemical aspects of organ systems and tissue, cells, proteins, enzymes, insulins and sugars, lipids, nucleic acids, amino acids, polypeptides, steroids, and vitamins and nutrition, among other topics. Fully updated to address recent advances, the new edition features fresh discussions on hypothalamic releasing hormones, DNA editing with CRISPR, new functions of cellular prions, plant-based diet and nutrition, and much more.Grounded in problem-driven learning, this new edition features clinical case studies, applications, chapter summaries, and review-based questions that translate basic biochemistry into clinical practice, thus empowering active clinicians, students and researchers.

    • Freshwater Fishes of the Eastern Himalayas

      • 1st Edition
      • July 23, 2021
      • Waikhom Vishwanath
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 3 9 1 7
      • eBook
        9 7 8 0 1 2 8 2 3 6 0 8 6
      Freshwater Fishes of the Eastern Himalayas provides a guide to describe the internationally accepted methods used in the accurate identification of fishes, morphometry, i.e., body proportions, meristics, i.e., counts of countable characters, viz., scales, fin rays, pores, vertebrae etc., characters of bones wherever necessary, special characters, viz., serrations of fin spines, axillary lobes, lobes, color patterns, etc. All the available taxa of the region are covered, making this an essential reference that provides the original description of genera and species. Diagnostic characters in the book can be easily examined by an unaided eye or by a binocular dissecting microscope with transmitted light.

    • Paclitaxel

      • 1st Edition
      • October 8, 2021
      • Mallappa Kumara Swamy + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 9 5 1 8
      • eBook
        9 7 8 0 3 2 3 9 0 9 5 2 5
      Paclitaxel: Sources, Chemistry, Anticancer Actions, and Current Biotechnology provides a comprehensive survey of Paclitaxel and its derivatives chemistry, biosynthesis and anticancer activities. In addition, biotechnological methods, including cell cultures, the use of bioreactors and metabolic engineering strategies to improve Paclitaxel production are also discussed. The book discusses topics such as mechanisms of action against cancer, novel forms of Paclitaxel for an effective cancer treatment, strategies for enhancing its bioavailability, and the application of nanocarriers for its delivery and chemotherapy of cancer. This is a valuable resource for cancer researchers, biotechnologists and members of biomedical field who are interested in the promising anticancer qualities of this antineoplastic drug and how to enhance them for better treatments.

    • Spatiotemporal Modeling of Stem Cell Differentiation

      • 1st Edition
      • September 7, 2021
      • William E. Schiesser
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 7 9 7 2
      • eBook
        9 7 8 0 3 2 3 9 1 4 1 3 0
      Spatiotemporal Modeling of Stem Cell Differentiation: Partial Differentiation Equation Analysis in R covers topics surrounding how stem cells evolve into specialized cells during tissue formation and in diseased tissue regeneration. As the process of stem cell differentiation occurs in space and time, the mathematical modeling of spatiotemporal development is expressed in this book as systems of partial differential equations (PDEs). In addition, the book explores important feature of six PDE model which can represent, for example, the development of tissue in organs. In addition, the book covers the computer-based implementation of example models through routines coded (programmed) in R. The routines described in the book are available from a download link so that example models can be executed without having to first study numerical methods and computer coding. The routines can then be applied to variations and extensions of the stem differentiation models, such as changes in the PDE parameters (constants) and the form of the model equations.

    • Biosensors for Single-Cell Analysis

      • 1st Edition
      • October 26, 2021
      • Jian Chen + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 8 9 8 4 1 6
      • eBook
        9 7 8 0 3 2 3 8 8 5 5 9 1
      Biosensors for Single-Cell Analysis explores a wide range of biosensor technologies and their applications in single-cell characterization and analysis. Sections cover key biophysical and chemical single-cell properties that consider proteomic, metabolic, electrical, mechanical and optical properties. Each chapter features key definitions and case studies, providing detailed guidance for researchers who want to replicate covered solutions in their work. Tutorial sections, evaluations of the current state-of-the-field and future developments are also included. Microfluidic approaches to characterization, such as microfluidic impedance flow cytometry and microfluidic flow cytometry are considered alongside more conventional approaches, such as mass spectroscopy, fluorescent and mass flow cytometry. Additionally, key types of biosensors are covered, including atomic force microscopy, micropipette aspiration, optical tweezers, microfluidic hydrodynamic stretchers, microfluidic constriction channel and microfluidic optical stretchers.

    • Neurocognitive Mechanisms of Attention

      • 1st Edition
      • March 16, 2021
      • Golnaz Baghdadi + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 0 9 3 5 8
      • eBook
        9 7 8 0 3 2 3 9 0 9 3 6 5
      Neurocognitive Mechanisms of Attention: Computational Models, Physiology, and Disease States describes the brain mechanisms underlying the attention control system, how those mechanisms are examined, how they operate in different disease states, and methods for improving them. Conceptual models of attention further explore their functional operation. Coverage includes the different types of attention, processing paths, brain anatomy, and attention’s role in memory and movement. Factors affecting attention are explored including nutrition, exercise, and genetics. Neurocognitive disorders impacting attention are discussed including autism, ADHD, OCD, depression, anxiety, schizophrenia, Alzheimer’s and Parkinson’s Disease. Assessment methods and treatments are uniquely set against the backdrop of current conceptual, computational, and oscillatory-based models to encourage researchers to pursue continued development of new diagnostic and therapeutic tools.

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