Genomics in Biosecurity
Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts
- 1st Edition - November 24, 2021
- Author: Manousos E. Kambouris
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 3 6 - 4
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 5 2 3 7 - 1
Genomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in defi… Read more
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Request a sales quoteGenomics in Biosecurity: Principles and Applications of Genomic Technologies in Expanded Biosecurity Concepts, in the Translational and Applied Genomics series, explains in definite and practical terms the applicability of genomic technologies in every aspect of biosecurity, from emergent diagnostics to bioterrorism, agroterrorism, next generation biowarfare, biosurveillance and risk assessment. This book offers an integrated discussion of genomics and GCBR (global catastrophic biological risks) events, considering both basic aspects of biosecurity genomics and application of genomic technologies to drive new solutions. Readers will find evidence-based strategies to apply genomics in disease and pathogen monitoring and diagnosis, and more.
Social aspects of GCBR events and genomic biosecurity, such as issues of terrorism, policy ethics, and practice, are also considered in-depth.
- Examines the use of genomics in pathogen monitoring and diagnosis, biosurveillance, and countermeasures for spontaneous and perpetrated events
- Discusses social, ethical, and policy aspects of GCBR events and the use of genomic technologies in biosecurity
- Empowers new solutions in biorestoration, biocrime, counterbioterrorism, disaster management, and humanitarian crisis response
- Features chapter contributions from a range of international specialists
Active researchers, basic and translational scientists, clinicians, postgraduates, and students in the areas of genetics, human genomics, pathology, security and biosecurity, bioengineering, and public health; infectious disease experts, public health scientists Students and active clinicians
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Contributors
- Part I: The spontaneous risk: Microbes and bugs
- Chapter 1: Exploring the concepts: Biosecurity, biodefense, and biovigilance
- Abstract
- References
- Chapter 2: The concept of humanome and the microbiomic dimension
- Abstract
- Introduction
- Humanome: A factuality or a game with words and suffixes?
- Defining the microbiome
- Exogenome: Within but also above cells and genomes
- The status quo between two sworn enemies and occasional partners
- Epilogue or projection?
- References
- Chapter 3: Global catastrophic biological risks: Nature and response
- Abstract
- Introduction
- The roots
- Bioresilience NG: The game humans play or perish?
- Personalized medicine: Applicable or not, where and how?
- References
- Chapter 4: Surveillance policies, levels, patterns, and techniques
- Abstract
- Introduction
- Dimensions, objectives, and methodologies
- Implementation
- Sensor categories
- The spatial aspect of surveillance
- References
- Chapter 5: The emerging pathogens: Nature, status, and threat
- Abstract
- Introduction
- Races, nations, and tribes: The map of the emergence events
- Cross-species infections: Rupturing the host-species barrier
- Conclusions
- References
- Chapter 6: Nonmicrobial biothreats: DNA, prions, and (bio)regulators/(bio)toxins
- Abstract
- Introduction
- The agents
- The threat team: Operating principles and resources
- Observe to salvage: Skills and procedure
- References
- Chapter 7: Public health microbiomics
- Abstract
- Introduction
- The powers that be
- Priorities and objectives
- Methodology: Requirements and comparative capabilities
- Advanced microbiomics in public health
- Expanding the horizon
- References
- Part II: The perpetrated biothreat: Bioterrorism, biocrime, and biowarfare
- Chapter 8: Bio-offense: Black biology
- Abstract
- Introduction
- Disruptive and destructive potential of agents
- Using neopathogens and “mining the ground”
- Creating metapathogens
- The offensive face of xenobiology
- Undermining the genome
- References
- Chapter 9: Bio-offense: Technical means, tactical approaches, operational orientations, and strategic concepts
- Abstract
- Introduction
- Dealing mayhem
- Mechanical delivery
- Biological delivery
- References
- Part III: Biodefense response and intervention
- Chapter 10: Biodefense response: Cognition and diagnosis
- Abstract
- Introduction
- Keeping one’s distance—A most healthy precaution
- Epitope supreme: Sensing the form
- Enter the code
- Microscopy: The all-seeing eye
- Culturomics: Nurturing the vile
- Conclusive prospects
- References
- Chapter 11: Biodefense build 2.0: The muscle
- Abstract
- Introduction
- Ploughing the field
- Carriers, dispensers, and vectors
- References
- Chapter 12: The genomic dimension in biodefense: Therapeutics
- Abstract
- Introduction
- Infectogenomics: A dimension positively ignored
- X/y/z-genomics
- Electroceuticals, radioceuticals, and other amenities
- One-for-all
- References
- Chapter 13: The genomic dimension in biodefense: Decontamination
- Abstract
- Introduction
- Cases, principles, and kinds
- References
- Chapter 14: Regulation and legislation
- Abstract
- Introduction
- A legal aspect of biosecurity and related fields
- Shifting geopolitics
- References
- Chapter 15: Epilogue: Resilience and preparedness, the case study of the United States
- Abstract
- Assessing the threat level
- Cognitive response to biothreat crisis
- Conclusions and prospects
- References
- Index
- No. of pages: 268
- Language: English
- Edition: 1
- Published: November 24, 2021
- Imprint: Academic Press
- Paperback ISBN: 9780323852364
- eBook ISBN: 9780323852371
MK
Manousos E. Kambouris
Dr. Manousos E. Kambouris serves as a Scientific Advisor for the Golden Helix Foundation, Craven House, London, UK, an international non-profit research organization aiming to advance research and education in the area of genomic and personalized medicine and as a Post Doc Researcher in the Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras. Dr. Kambouris has long participated in different aspects and applications of microbiology, human genomics, biosecurity and cancer research. In his own work, he pursues an integrative approach to microbiomics, employing various -omics-driven approaches and realizing their application in human health, selective and personalized medicine, and panbiosurveillance among other areas. He has published widely in such peer-reviewed journals as OMICS-JIB, Hemoglobin, Medical Mycology, FEMS Immunology & Medical Microbiology, Public Health Genomics, and Future Microbiology.
Affiliations and expertise
Scientific Advisor, The Golden Helix Foundation, Craven House, London, UK, and Post Doc Researcher, Laboratory of Pharmacogenomics and Individualized Therapy, Department of Pharmacy, University of Patras, Rio Patras, GreeceRead Genomics in Biosecurity on ScienceDirect