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    • Fundamentals of Pediatric Imaging

      • 3rd Edition
      • August 15, 2021
      • Lane F. Donnelly
      • English
      • Hardback
        9 7 8 0 1 2 8 2 2 2 5 5 3
      • eBook
        9 7 8 0 1 2 8 2 2 2 5 6 0
      Fundamentals of Pediatric Imaging, Third Edition presents the foremost techniques of pediatric medical image analysis and processing. It includes advanced imaging techniques, neuro applications, and highlights basic anatomy needed to understand this complex specialty. The book introduces the theory and concepts of pediatric digital image analysis and newly revised information on quality and safety topics, imaging modalities, imaging applications, and new discoveries in diseases and treatments. The newly revised edition provides updates in areas of expertise including neurologic, musculoskeletal, cardiac, chest, and GU imaging. Edited by Lane F. Donnelly, MD, recipient of the Society of Pediatric Radiology’s 2009 Singleton-Taybi Award, this book is sure to be a prime reference in pediatric medical imagining.

    • Inborn Errors of Immunity

      • 1st Edition
      • January 22, 2021
      • Asghar Aghamohammadi + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 0 2 8 4
      • eBook
        9 7 8 0 1 2 8 2 3 1 8 9 0
      Awareness among clinicians about PIDs, which consist of more than 400 different entities, plays an important role in ensuring that patients receive a timely diagnosis. Furthermore, clinicians who are educated about PIDs can give their patients access to optimal management of their condition, thus helping the patient achieve a better quality-of-life and long-term prognosis. Inborn Errors of Immunity: A Practical Guide provides the most up-to-date information for busy students, nurses, clinical residents, practicing physicians, and even basic researchers. Readers will benefit from a well-structured breakdown of complicated PID diseases, including approaches to their clinical signs/symptoms and immunologic/laborato... findings.

    • Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy

      • 1st Edition
      • Volume 3
      • November 26, 2021
      • Peder Larson
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 2 6 9 0
      • eBook
        9 7 8 0 1 2 8 2 2 2 7 0 6
      MRI with hyperpolarized carbon-13 agents is a powerful emerging imaging modality that can measure real-time metabolism in cells, animals, and humans. It uses endogenous, non-toxic contrast agents that a hyperpolarized, resulting in up to 100,000-fold increases in sensitivity. This technique uses no ionizing radiation, and is being applied in a range of human trials. It’s primary use is for metabolic imaging, but it can also measure perfusion, pH, and necrosis. Hyperpolarized Carbon-13 Magnetic Resonance Imaging and Spectroscopy is designed to be a one stop shop for understanding hyperpolarized 13C MRI. This book explains the principles of this imaging modality, the requirements for performing studies, shows how to interpret the results, and gives an overview of current biomedical applications. It is suitable for engineers, scientists and clinicians in radiology and biomedical imaging who want to understand this technology.

    • Smart Agrochemicals for Sustainable Agriculture

      • 1st Edition
      • December 1, 2021
      • Katarzyna Chojnacka + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 0 3 6 6
      • eBook
        9 7 8 0 1 2 8 1 7 0 3 7 3
      Smart Agrochemicals for Sustainable Agriculture proposes products that fulfill the need for chemicals that provide a sustainable delivery system for nutrients necessary to maximize the production of agricultural animals and plants while producing the smallest possible environmental footprint. This book addresses all aspects related to the production process, including chemical formulas, stability of formulations, and the application of the effect of its utilization. Over the past decade, biobased chemicals have received significant attention as candidate resource materials in fertilizers and agrochemicals production due to their renewability. Substitution of conventional raw materials with biobased requires a new approach towards the development of technology. On the other hand, the use of biobased chemicals, such as biostimulants, bioregulators and biofertilizers offers a new palette of products that are natural, thus their application does not pose an impact on the environment (residues) or cultivated plants.

    • Recent Highlights in the Discovery and Optimization of Crop Protection Products

      • 1st Edition
      • March 24, 2021
      • Peter Maienfisch + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 0 3 5 2
      • eBook
        9 7 8 0 1 2 8 2 1 0 3 6 9
      Recent Highlights in the Discovery and Optimization of Crop Protection Products highlights the most prominent, recent results in the search for safe and effective new crop protection products. With a focus on the design, synthesis, optimization and/or structure-activity relationships of new chemistries targeting insect, disease, weed, nematode, vector and animal parasite control, the book also includes recent developments in crop enhancement chemistries and new approaches to crop protection products. The inclusion of information on testing tools, green chemistry approaches, and the latest discovery tools, like modeling, structure-based design, and testing tools makes this volume complete. Based on key presentations given at the 14th International IUPAC conference on Crop Protection, May 19-24, 2019 in Ghent, Belgium, this book includes the many exciting new discoveries and findings reported. It is designed to inspire additional research and advancement in the field.

    • Organ Repair and Regeneration

      • 1st Edition
      • January 14, 2021
      • Giuseppe Orlando + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 4 5 1 5
      • eBook
        9 7 8 0 1 2 8 1 9 4 5 2 2
      Organ Repair and Regeneration: Preserving Organs in the Regenerative Medicine Era encompasses updates on all organs, from the kidneys, to the lungs, liver, pancreas, intestines, and beyond. Chapters cover the pathophysiology of ischemia-reperfusion... repairing organs with MSC, repairing cardiac allografts in situ, and much more. The book conceptualizes the idea that the modern approach to organ preservation is ante literam, a form of organ repair and regeneration which, per se, is referred to as a field of health sciences under the umbrella of regenerative medicine. This book demonstrates the merging of regenerative medicine and organ transplantation.

    • Epidemiology of Brain and Spinal Tumors

      • 1st Edition
      • April 9, 2021
      • Jahangir Moini + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 7 3 6 8
      • eBook
        9 7 8 0 1 2 8 2 1 7 5 5 9
      Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors.

    • The Intestine

      • 1st Edition
      • June 15, 2021
      • Ahmed El-Hashash + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 1 2 6 9 1
      • eBook
        9 7 8 0 1 2 8 2 1 2 7 1 4
      The intestine is among the leading organs, in which several cutting edge in vitro and in vivo research tools and approaches have recently been developed and used to investigate stem cell biology/function, and the potential applications of stem cells in the treatment of intestinal diseases. These cutting-edge research tools and approaches involve human and murine organoid cultures, genetic editing in vitro and in vivo, human induced pluripotent cell (iPS cell) models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure diseases. Stem Cell Innovation in Health and Disease: Volume 1: The Intestine contains two major sections describing cutting edge research for understanding stem cell functions in the intestine, and for developing methods to bring stem cells from bench to bedside; respectively. Each section includes insights ranging from using mouse and human organoid cultures, genetic editing in vitro and in vivo, and human induced pluripotent cells (iPSCs) to study stem cell functions and model intestinal diseases, through the cutting-edge research, including the potential application of iPSCs, ESCs and blood stem cells (stem cell transplants) in the treatment of intestinal diseases/disorders. This volume, therefore, discusses the fact-based promise of stem cells and regenerative medicine in the intestine in the real world.

    • Sex and Gender Differences in Alzheimer's Disease

      • 1st Edition
      • July 23, 2021
      • Maria Teresa Ferretti + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 3 4 4 0
      • eBook
        9 7 8 0 1 2 8 1 9 3 4 5 7
      Sex and Gender Differences in Alzheimer’s Disease: The Women’s Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer’s disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer’s disease families, in the frame of a precision medicine approach to Alzheimer’s disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagnosis, treatment, clinical trials development, socioeconomic factors, and psychosocial support. Alzheimer’s disease, the most common form of dementia, remains an unmet medical need for the planet. Wide interpersonal variability in disease onset, presentation, and biomarker profile make Alzheimer’s a clinical challenge to neuroscientists, clinicians, and drug developers alike, resulting in huge management costs for health systems and society. Not only do women represent the majority of Alzheimer’s disease patients, but they also represent two-thirds of caregivers. Understanding sex and gender differences in Alzheimer’s disease will lead to novel insights into disease mechanisms, and will be crucial for personalized disease management strategies and solutions, involving both the patient and their family. Endorsements/Reviews... "There is a clear sex and gender gap in outcomes for brain health disorders like Alzheimer’s disease, with strikingly negative outcomes for women. This understanding calls for a more systematic way of approaching this issue of inequality. This book effectively highlights and frames inequalities in all areas across the translational spectrum from bench-to-bedside and from boardroom-to-policy and economics. Closing the Brain Health Gap will help economies create recovery and prepare our systems for future global shocks." Harris A. Eyre MBBS, PhD, co-lead, Neuroscience-inspire... Policy Initiative, OECD and PRODEO Institute. Instructor in Brain Health Diplomacy, Global Brain Health Institute, UCSF and TCD. "Sex and Gender Differences in Alzheimer's disease is the most important title to emerge on Alzheimer's disease in recent years.This comprehensive, multidisciplinary book is a must read for anyone with a serious interest　in dementia prevention, diagnosis, treatment, care, cure and research. Precision medicine is the future of healthcare and this book represents an incredible and necessary resource to guide practice, policy and research in light of the fact that Alzheimer's disease disproportionately affects women. The combination of contributions from the most eminent experts and the most up-to-date research makes this an invaluable resource for clinicians, care providers, academics, researchers and policy makers. Given the complex nature of dementia and the multiple factors that influence risk and disease trajectory the scope of the book is both impressive and important covering sex differences in neurobiological processes, sex and gender differences in clinical aspects and gender differences linked to socioeconomic factors relevant to Alzheimer's disease. If you work in Alzheimer's disease, or indeed other dementias, then Sex and Gender Differences in Alzheimer's disease is a must have for your bookshelf." -- Sabina Brennan, PhD., C.Psychol.,PsSI., National representative for Ireland on Alzheimer Disease International's Medical and Scientific Advisory Panel

    • Handbook on the Toxicology of Metals: Volume I: General Considerations

      • 5th Edition
      • November 30, 2021
      • Gunnar F. Nordberg + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 2 3 2 9 2 7
      • eBook
        9 7 8 0 1 2 8 2 3 2 9 3 4
      Handbook on the Toxicology of Metals, Fifth Edition, Volume I: General Considerations is the first volume of a two-volume work that gives an overview and covers topics of general importance including reviews of various health effects of trace metals. The book emphasizes toxic effects in humans, along with discussions on the toxic effects of animals and biological systems in vitro when relevant. The book has been systematically updated with the latest studies and advances in technology and contains several new chapters. As a multidisciplinary resource that integrates both human and environmental toxicology, the book is a comprehensive and valuable reference for toxicologists, physicians, pharmacologists, and environmental scientists in the fields of environmental, occupational and public health.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology