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Books in Life sciences

  • Novel Therapeutic Approaches Targeting Oxidative Stress

    • 1st Edition
    • February 18, 2022
    • Pawan Kumar Maurya + 1 more
    • English
    Novel Therapeutic Approaches Targeting Oxidative Stress investigates the role of oxidative stress in disease and explores the latest methods and approaches to targeting oxidative stress for treatment and diagnosis. The book begins with an introduction to oxidative stress and its significance. Subsequent sections cover biochemical methods for detecting free radicals and novel therapeutic approaches for targeting oxidative stress in a number of different diseases. This includes age-related illnesses, neuropsychiatric disorders such as schizophrenia and bipolar disorder, and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease. Novel approaches for targeting oxidative stress in cancer and cardiovascular diseases are also explored. The book then moves on to discuss advances in drug delivery systems and detecting oxidative stress biomarkers using biosensors. It concludes with case studies that illustrate the targeting of oxidative stress and future perspectives.

  • MicroRNA in Human Malignancies

    • 1st Edition
    • February 17, 2022
    • Massimo Negrini + 2 more
    • English
    MicroRNA in Human Malignancies offers a deep overview of the role and translational significance of miRNAs in the development of cancer and other malignancies. The book establishes the foundations of the field by covering essential mechanisms and the translational potential of miRNAs in the field of oncology. Specific topics covered include invasion and metastasis, miRNAs and metabolism, and opportunities of miRNAs in therapeutics. Chapters on diseases include content on disease-related pathophysiology, as well as diagnostic, prognostic and predictive value. This book is an essential reference for students entering the field, as well as researchers and investigators.

  • Xenobiotics in Chemical Carcinogenesis

    Translational Aspects in Toxicology
    • 1st Edition
    • February 17, 2022
    • Akhileshwar Kumar Srivastava + 3 more
    • English
    Xenobiotics in Chemical Carcinogenesis: Translational Aspects in Toxicology covers the translational toxicology of xenobiotics substances in carcinogenesis by explaining the toxicokinetic and toxicodynamic, toxicogenomic, biotransformation, and resistance mechanisms in the human body. The book begins with a historical review and link to future prospects for chemical carcinogenesis. It discusses major environmental xenobiotics and their risks in inducing cancer, along with content on toxic xenobiotics and their routes of exposure in humans, the role of xenobiotic metabolism in carcinogenesis, and the toxicokinetic and toxicodynamic of xenobiotics in cancer development. Lastly, the book explores current achievements such as using toxicogenomics for predicting the carcinogenicity of xenobiotic substances and the challenges posed by carcinogenic xenobiotic substances when examining preventive methods, diagnosis, and the development of anticancer drugs for specific toxicants.

  • Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma

    • 1st Edition
    • February 17, 2022
    • Michael Fehlings + 3 more
    • English
    Neural Repair and Regeneration after Spinal Cord Injury and Spine Trauma provides readers with a comprehensive overview on the most up-to-date strategies to repair and regenerate the injured spinal cord following SCI and spine trauma. With contributions by international authors, chapters put regenerative approaches in context, allowing the reader to understand the challenges and future directions of regenerative therapies. Recent clinical trial advancements are thoroughly discussed, with the impact of trial findings addressed. Additionally, major ongoing clinical trials are included with thoughts from experts in the field. Recent clinical practice guidelines for the management of traumatic spinal cord injury are featured throughout. These guidelines are quickly being adopted as the standard of care worldwide, and the comprehensive information found within this book will place these recommendations in context with current knowledge surrounding spinal cord injury and spine trauma.

  • Hormones, Regulators and Hippocampus

    • 1st Edition
    • Volume 118
    • February 16, 2022
    • Gerald Litwack
    • English
    Hormones, Regulators and Hippocampus, Volume 118 in the Vitamins and Hormones serial highlights new advances in the field, with this new volume presenting interesting chapters, including Thyroid hormone regulation of adult hippocampal neurogenesis – putative molecular and cellular mechanisms, Synergistic gene regulation by thyroid hormone and glucocorticoid in the hippocampus, Oxytocin and vasopressin in the hippocampus, Steroid hormones and hippocampal neurogenesis in the adult mammalian brain, Steroidogenic enzymes in the hippocampus: transcriptional regulation aspects, Ectonucleotidases in the hippocampus: spatial distribution and expression after ovariectomy and estradiol replacement, and much more.

  • Elements of Marine Ecology

    • 5th Edition
    • February 16, 2022
    • Frances Dipper
    • English
    Elements of Marine Ecology, Fifth Edition focuses on marine ecology as a coherent science, providing undergraduate students with an essential foundation of knowledge in the structure and functioning of marine ecosystems. The text reflects ecological groupings such as the pelagic lifestyle vs. the benthic lifestyle. In addition, background oceanographic material, previously in various chapters, is consolidated in the first chapter. The broad definition of ecology is the study of organisms in relation to their surroundings. This book presents marine ecology as a coherent science, providing undergraduate students with an essential foundation of knowledge in the structure and functioning of marine ecosystems. This new edition has been thoroughly revised and updated to meet the needs of today’s courses and now includes worldwide examples, all thoroughly updated with brand new chapters.

  • The Lung in Autoimmune Diseases

    • 1st Edition
    • Volume 17
    • February 16, 2022
    • Fabiola Atzeni + 2 more
    • English
    The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung’s functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases.

  • Digestive System Malignancies

    • 1st Edition
    • February 16, 2022
    • Constantine P. Spanos
    • English
    Digestive System Malignancies provides an up-to-date overview on the most relevant diagnostic techniques, staging of malignancies, and current therapeutic modalities for digestive system malignancies. With coverage from esophageal, gastric and pancreatic cancers, to colon, anal and peritoneal surface, this reference offers a wide-ranging guide to malignancies throughout the digestive system. The use of engaging infographics provides an "at-a-glace" perspective on the subject, allowing users to retain a large amount of information without scrolling through large text or complex algorithms. This is an important reference for clinicians, surgeons, medical students and scientists that need a quick reference on digestive system malignancies.

  • Diabetic Neuropathy

    • 1st Edition
    • February 16, 2022
    • Mitra Tavakoli
    • English
    Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials. This succinct reference focuses on the current data and research on diabetic neuropathy and is essential reading for researchers in endocrinology, neurology and pharmacology, along with clinicians that need to better understand the novel pathogenetic pathways leading to diabetic neuropathy and the treatments.

  • Rhizosphere Engineering

    • 1st Edition
    • February 15, 2022
    • Ramesh Chandra Dubey + 1 more
    • English
    Rhizosphere Engineering is a guide to applying environmentally sound agronomic practices to improve crop yield while also protecting soil resources. Focusing on the potential and positive impacts of appropriate practices, the book includes the use of beneficial microbes, nanotechnology and metagenomics. Developing and applying techniques that not only enhance yield, but also restore the quality of soil and water using beneficial microbes such as Bacillus, Pseudomonas, vesicular-arbuscular mycorrhiza (VAM) fungi and others are covered, along with new information on utilizing nanotechnology, quorum sensing and other technologies to further advance the science. Designed to fill the gap between research and application, this book is written for advanced students, researchers and those seeking real-world insights for improving agricultural production.

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