The Lung in Autoimmune Diseases

1st Edition, Volume 17 - February 16, 2022
Editors: Fabiola Atzeni, Jose Gomez-Puerta, Jacobo Sellares
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 0 8 3 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 0 8 4 - 2

The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, progno… Read more

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The Lung in Autoimmune Diseases, Volume Seventeen identifies and describes the role of the lung in the most common systemic autoimmune diseases. From disease patterns, prognosis and risks to treatment, this book provides a comprehensive approach for the role of the lung in autoimmune diseases and the influence of autoimmune disease on the lung’s functionality. In recent years, there is increasing knowledge in the field, including lung infection in early disease stages, mechanisms involved in lung damage, and new treatments. Recognition of lung involvement and implementation of some specific therapies is an important issue for clinicians dealing with systemic autoimmune diseases.

Cover image
Title page
Table of Contents
Handbook of Systemic Autoimmune Diseases
Copyright
Dedication
Contributors
Chapter 1. Interstitial pneumonia with autoimmune features
Epidemiology
IPAF classification
Mechanisms of disease
Prognosis
Treatment considerations
Criticisms and potential shortcomings of the IPAF designation
Conclusions
Take home message
Chapter 2. Interstitial lung disease and rheumatoid arthritis
Introduction
Risk factors and pathogenesis
Clinical manifestations
Diagnostic imaging
Different diagnostic methods
Therapy
Conclusions
Take-home messages
Chapter 3. Lung involvement in SLE
Pleural involvement
Interstitial lung disease
Pulmonary arterial hypertension
Diffuse alveolar hemorrhage and pulmonary vasculitis
Acute lupus pneumonitis
Shrinking lung syndrome
Chapter 4. Sjogren's syndrome and lung involvement
Introduction
Airway disease
Interstitial lung disease
Other pulmonary manifestations
Chapter 5. Lung involvement in systemic sclerosis
Epidemiology
Pathogenesis
Clincal presentation
Diagnosis of ILD
Screening for ILD
ILD monitoring and progression
Prognosis
Treatment
COVID-19 and systemic sclerosis
Summary
Take-home messages
Chapter 6. Inflammatory myopathy, mixed connective tissue disease, and antisynthetase syndrome
Introduction
The lung in inflammatory myopathies
The lung in mixed connective tissue disease
Chapter 7. Lung involvement in ANCA-associated vasculitis
Introduction
Pulmonary manifestations shared among all types of AAV
Pulmonary manifestations primarily seen in GPA and EGPA
Pulmonary manifestations primarily seen in GPA
Pulmonary manifestations primarily seen in EGPA
Treatment of lung involvement in ANCA-associated vasculitis
Conclusions
Chapter 8. The lung in autoimmune diseases: sarcoidosis
Introduction
Lymphatic involvement
Parenchymal lung involvement
Pulmonary vascular involvement
Diagnosis of sarcoidosis
Treatment
Conclusion
Take home messages
Chapter 9. COVID-19 and lung involvement
Introduction
Epidemiology
Virology
Transmission
Pathogenesis
Clinical features
Laboratory findings
Imaging findings
Pathology findings
Diagnosis
Management
Conclusion
Take-home messages
Index

Fabiola Atzeni

Fabiola Atzeni, MD, PhD is currently Full Professor and Head of the Rheumatology Unit, University of Messina, Messina, Italy. Her clinical and research interest lies in immunotherapies in autoimmune diseases with particular focus on the investigation and management of differential response to biological therapies in rheumatoid arthritis (RA) and Spondyloarthritis (SpA), and cardiovascular aspects of the different rheumatic diseases with particular emphasis on arteriosclerosis. Dr. Atzeni has co-authored over 400 publications in peer-reviewed journals and several book chapters, is a regular reviewer for several international journals. She is involved in several international and national meetings focused on cardiovascular and infection aspects.

Affiliations and expertise

Full Professor and Head of Rheumatology Unit, University of Messina, Messina, Italy.

Jose Gomez-Puerta

Jose A. Gómez-Puerta is a Specialist in Internal Medicine and Rheumatology and Ph.D. in Biopathology by the University of Barcelona. He received further training in the Rheumatology Unit of Guy’s Hospital, London, UK, and the Lupus Unit, St. Thomas’ Hospital, London, UK, in 1997 and 2001, respectively. He also finished the Master in Autoimmune Diseases at Universidad de Barcelona and moved for an appointment as Post-Doctoral Research Fellow at Brigham and Women’s Hospital at Harvard Medical School, Boston, USA from 2011 to 2014. In 2014, Dr Gómez-Puerta obtained his degree in Master of Public Health at Harvard School of Public Health, Boston. USA. His work has focused on the study of Autoimmune and immune mediated diseases and he has published more than 100 original papers, brief notes or reviews in peer-reviewed journals and over 160 communications in national and international meetings. Currently, Dr Gómez-Puerta is the Head of Department of Rheumatology At Hospital Clinic, Barcelona and associate professor of Rheumatology at University of Barcelona, Spain

Affiliations and expertise

Specialist in Internal Medicine and Rheumatology, University of Barcelona, Barcelona, Catalonia, Spain

Jacobo Sellares

Dr. Jacobo Sellarés Torres is a recognized researcher in chronic respiratory diseases, and especially in diffuse interstitial lung diseases (DILD). He is coordinator of the Multidisciplinary Program of ILD at Hospital Clínic, Barcelona, which has been recognized by a variety of organizations, such as the Spanish Society of Pneumology (SEPAR), Orphanet, the European Reference Network (ERN) and the International Sarcoidosis Society (WASOG). Dr. Sellarés Torres belongs to the "Inflammation and repair of respiratory diseases" team of Area 2 of IDIBAPS, Barcelona who specializes in the methodology of systems biology and diseases chronic respiratory diseases. Dr. Sellares is also a research member of the Barcelona Research Network (BRN) and of the CIBER of respiratory diseases (CIBERES), and he actively collaborates in different national and international EPID registration networks. Dr. Sellarés has been a mentor of Respirarory Fellows (Hospital Clinic) since 2019 and reviewer for "Consell Tècnic de Medicina del Consell Català de la Formació Continuada (FC) de les Professions Sanitàries (PS), Departament de Salut de la Generalitat de Catalunya".

Affiliations and expertise

Pneumology Department, Hospital Clinic de Barcelona, Spain