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Books in Life sciences

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    • Cannabis and the Developing Brain

      • 1st Edition
      • August 18, 2022
      • Miriam Melis + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 4 9 0 7
      • eBook
        9 7 8 0 1 2 8 2 3 6 4 1 3
      Marijuana is the most commonly used psychotropic drug in the United States, after alcohol. With the legalization and decriminalization of cannabis, momentum continues to build and propelled by the reduction of stigma associated to its consumption, there is growing concern regarding the long-term impact on brain function and behavior. Cannabis and the Developing Brain aims to provide comprehensive research on the effects of cannabis during neurodevelopment stages (i.e., perinatal and adolescent ages). This book introduces readers to vivo neural circuits, molecular and cellular mechanisms affected by cannabis exposure during three different temporal windows of brain vulnerability. Second, it offers a unique insight to shared neurobiological features of cannabinoid exposure during different developmental periods. Lastly, Cannabis and the Developing Brain determines the adverse impact of developmental cannabinoid exposure on specific cognition, emotion and behaviors.

    • Microneedles

      • 1st Edition
      • February 6, 2022
      • Kevin Ita
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 1 1 4
      • eBook
        9 7 8 0 3 2 3 9 7 2 3 4 5
      Microneedles explores the design, fabrication and use of microneedles for drug and vaccine delivery. This book discusses the contemporary status of the field, describing several areas in detail, including the distinct types of microneedles (dissolving, solid, coted, hollow and hydrogel-forming). The anatomy of the eye is also described to facilitate an understanding of microneedle-assisted ocular drug delivery. Finally, the book provides a detailed discussion of microneedle use in the field of diagnostics, with a chapter dedicated to the mathematical modeling of microneedle-mediated drug delivery. As microneedles can be used by research scientists in academia and in industry, this book will be ideal for regulatory scientists and graduate students who find the topic relevant to their area of study.

    • Cerebrospinal Fluid and Subarachnoid Space

      • 1st Edition
      • October 8, 2022
      • R. Shane Tubbs + 4 more
      • English
      • Hardback
        9 7 8 0 1 2 8 1 9 5 0 7 9
      • eBook
        9 7 8 0 1 2 8 1 9 5 0 8 6
      Cerebrospinal Fluid and Arachnoid Space Volume 2: Pathology and Disorders is the first book devoted to the comprehensive clinical anatomy of the cerebrospinal fluid for neurosurgeons, neurologists, and neuroscientists. Knowledge of the cerebrospinal fluid (CSF) and the subarachnoid space is necessary for almost all fields of medicine. The book covers a wide swath of topics related to CSF with a focus on topics relevant to neuroscience specialists including researchers, neurologists, neurosurgeons, and neuroradiologists. Topics span from neuroanatomy, neurophysiology, CSF in different disease states and more. Various fresh and fixed cadaveric photographs helps readers obtain a better understanding of anatomy and complications related to CSF.

    • Bidirectional Gene Promoters

      • 1st Edition
      • November 23, 2022
      • Fumiaki Uchiumi
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 7 8 7 6
      • eBook
        9 7 8 0 1 2 8 1 9 4 6 1 4
      • eBook
        9 7 8 0 1 2 8 1 9 0 6 8 5
      Recent studies in human genetics and in silico analyses have revealed that a number of genes are head-head orientated with other genes or non-coding RNAs. The expression of regulatory element-containing 5’-upstream regions of gene pairs are referred to as bi-directional promoters and are thought to have a key role in biological regulatory mechanisms. For example, tumor suppressor protein-encoding TP53 and BRCA1 genes are head-head bound with WRAP53 and NBR2, respectively. DNA-repair factor-encoding ATM and PRKDC (DNA-PKcs) genes have bidirectional partner NPAT and MCM4, respectively. Surveillance of the human DNA database has revealed that the numbers of DNA repair/mitochondrial function/immune response-associated genes are bound with other genes that are transcribed to opposite direction. The observations may encourage us to investigate in the molecular mechanisms how DNA repair/mitochondrial function/immune response-associated genes are regulated by bidirectional promoters. Not only protein-coding genes, but also quite a few ncRNAs, which play important roles in various cellular events, are transcribed under the regulation of the bidirectional promoters. More importantly, we know that dysregulation in the promoter activity and transcription initiation of genes might cause human diseases.

    • Immunopathology, Diagnosis and Treatment of HPV induced Malignancies

      • 1st Edition
      • August 2, 2022
      • Prashant Khare + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 7 9 7 1
      • eBook
        9 7 8 0 3 2 3 9 8 6 4 4 1
      Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies.

    • Molecular, Cellular, and Metabolic Fundamentals of Human Aging

      • 1st Edition
      • October 23, 2022
      • Evandro Fei Fang + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 6 1 7 2
      • eBook
        9 7 8 0 3 2 3 9 1 6 1 8 9
      Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion. The book also considers the impact of aging within the immune system, the relationship between aging and diseases such as cancers and neurodegenerative conditions, and provides an overview on the dialogue surrounding the topic of aging beyond basic biology.

    • The Veterinarian’s Guide to Animal Welfare

      • 1st Edition
      • November 26, 2022
      • Bonnie V. Beaver + 1 more
      • English
      • Hardback
        9 7 8 0 3 2 3 9 1 0 1 8 7
      • eBook
        9 7 8 0 3 2 3 9 1 0 1 9 4
      The Veterinarian’s Guide to Animal Welfare provides an overview of various aspects of animal welfare that are particularly relative to the veterinary profession. The book explores various ways of viewing and assessing welfare, as well as the numerous factors that influence perceptions. Emphasis is placed on contemporary issues across, and within, major species groups. The book's authors are internationally known experts in the veterinary aspects of animal welfare and have written numerous articles on animal welfare, behavior, euthanasia and the human-animal bond. This book is written for the veterinary profession and was designed to be used as a textbook for animal welfare courses at colleges and schools of veterinary medicine. It complements the Model Curriculum for the Study of Animal Welfare (AVMA 2015) and its attendant course syllabus. This is an important resource for graduate veterinarians seeking to improve their understanding of the numerous aspects of animal welfare.

    • Artificial Intelligence and Machine Learning for EDGE Computing

      • 1st Edition
      • April 26, 2022
      • Rajiv Pandey + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 4 0 5 4 0
      • eBook
        9 7 8 0 1 2 8 2 4 0 5 5 7
      Artificial Intelligence and Machine Learning for Predictive and Analytical Rendering in Edge Computing focuses on the role of AI and machine learning as it impacts and works alongside Edge Computing. Sections cover the growing number of devices and applications in diversified domains of industry, including gaming, speech recognition, medical diagnostics, robotics and computer vision and how they are being driven by Big Data, Artificial Intelligence, Machine Learning and distributed computing, may it be Cloud Computing or the evolving Fog and Edge Computing paradigms. Challenges covered include remote storage and computing, bandwidth overload due to transportation of data from End nodes to Cloud leading in latency issues, security issues in transporting sensitive medical and financial information across larger gaps in points of data generation and computing, as well as design features of Edge nodes to store and run AI/ML algorithms for effective rendering.

    • Bacterial Survival in the Hostile Environment

      • 1st Edition
      • September 28, 2022
      • Ashutosh Kumar + 1 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 8 0 6 0
      • eBook
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      Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics.

    • Functional Foods and their Implications for Health Promotion

      • 1st Edition
      • December 3, 2022
      • Ioannis Zabetakis + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 3 8 1 1 0
      • eBook
        9 7 8 0 1 2 8 2 3 8 1 2 7
      Functional Foods and Their Implications for Health Promotion presents functional foods, from raw ingredients to the final product, providing a detailed explanation on how these foods work and an overview of their impact on health. The book presents the functions of food against disease and discusses how healthier foods can be produced. Broken into four parts, the book presents a deep dive into plant-derived functional foods, dairy foods, marine food and beverages. The book includes case studies, applications, literature reviews and coverage of recent developments.Intende... for nutritionists, dieticians, food technologists, as well as students and researchers working in nutrition, dietetics, and food science, this book is sure to be a welcomed resource.

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