Immunopathology, Diagnosis and Treatment of HPV induced Malignancies

1st Edition - August 2, 2022
Imprint: Academic Press
Editors: Prashant Khare, Ashish Jain
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 7 9 7 - 1
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 8 6 4 4 - 1

Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explai… Read more

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Immunopathology, Diagnosis and Treatment of HPV induced Malignancies focuses on the human papilloma virus infection and associated cancers. In ten chapters, the book explains the deep knowledge about molecular mechanism in HPV pathogenesis and recent advanced tools applied in the field of HPV induced cancer and cures. In a nutshell, the book gives new insights and the associated challenges involved in the identification of promising drug and vaccine targets, current diagnostic tools, and advancements in current therapies against HPV induced cancers and other malignancies.

Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter 1: An overview of HPV: Causes, symptoms, and clinical manifestations
Abstract
1: Introduction
2: Structure and biology of HPV
3: Causes of HPV infection
4: HPV symptoms
5: HPV diagnosis
6: Clinical manifestation of HPV infections
7: Prevention of HPV infection
8: Wart treatment
9: HPV vaccines
10: Conclusion
References
Chapter 2: Pathogenesis and immune response against HPV infection
Abstract
1: Introduction
2: Pathogenesis and immune response associated with HPV infection
3: Evasion of host immune response
4: Conclusion
References
Chapter 3: Malignancies associated with HPV
Abstract
Acknowledgment
1: Introduction
2: Malignancies associated with HPV
3: Treatment of HPV-associated malignancies
4: Conclusion
References
Chapter 4: Immunological aspects of HPV/HIV co-infection and risk of gynecological diseases
Abstract
1: Introduction
2: Immunological aspects of HPV infection
3: The impact of immunological aspects of HPV on HIV infection
4: HPV-HIV co-infections and gynecological disorders
5: Conclusion
References
Chapter 5: Cervicovaginal microbiota and HPV-induced cervical cancer
Abstract
1: Introduction
2: Human papillomavirus (HPV)
3: Cervicovaginal microbiota (CVM)
4: CVM, sexually transmitted infections (STIs), and CC
5: Restoration of CVM to prevent CC
6: Conclusion
References
Chapter 6: Current diagnostic tools for HPV
Abstract
1: Introduction
2: Diagnostic techniques for HPV infection
3: Screening strategies
4: Conclusion
References
Chapter 7: Animal models for the discovery of therapeutic and prophylactic measure against HPV-induced malignancies
Abstract
1: Introduction
2: Animal models for therapeutic and prophylactic measures against HPV
3: Conclusion
References
Chapter 8: Potential drug targets against HPV and repurposing of existing drugs
Abstract
1: Introduction
2: Potential drug targets against HPV
3: Repurposing of existing drugs against HPV
4: Conclusion
References
Chapter 9: Recent advances and strategies in vaccine development against HPV
Abstract
1: Introduction
2: Requirement and type of HPV vaccine
3: Candidate for the HPV vaccine development
4: Licensed vaccines against HPV
5: Development of the future HPV vaccine
6: The future of HPV vaccination
7: Conclusion
References
Chapter 10: Available immunotherapies and future opportunities to prevent HPV-associated cancers
Abstract
1: Introduction
2: Present therapeutic options for HPV-associated cancers
3: Immunotherapies for HPV-associated cancers
4: CC
5: HNSCC
6: Oral cancer
7: Conclusion
References
Index

Prashant Khare

Dr. Prashant Khare is a Vice President (R&D) at Xenesis Institute, Absolute in Gurugram (Haryana), India. Previously, he was a Ramalingaswami Fellow and Scientist D in the Department of Microbiology at the All India Institute of Medical Sciences, Bhopal, India. He completed his PhD from the Division of Parasitology at the Central Drug Research Institute in Lucknow, (Uttar Pradesh), India. He has almost five years of postdoctoral experience from the Baylor Institute for Immunology Research and UT Southwestern Medical Center in Dallas, Texas, USA, and more than 15 years of research experience in the field of infectious biology, immunology, vaccine, and drug development. He has published more than 30 research papers in highly reputable international journals such as Nature Immunology and Nature Communication. He has reviewed publications and served in an editorial role for several international journals as well.

Affiliations and expertise

Director (R&D), Center for Advanced Biotechnology Research Absolute Foods, Gurugram, Haryana, India

Ashish Jain

Dr. Ashish Jain is working as an Assistant Professor (senior scale) since last eleven years in the Department of Microbiology, Smt. CHM College Ulhasnagar; affiliated with the University of Mumbai (Maharashtra), India. He has completed his PhD from Division of Endocrinology, Central Drug Research Institute, Lucknow (Uttar Pradesh) India on spermicides and anti-Trichomonas molecules and their mode of action. He has published more than 20 reputed international research papers and reference books in the field of Sexually transmitted infections and reproductive biology and credited international patents in his account. He is a recognized postgraduate teacher and PhD guide of University of Mumbai in Microbiology subject. Presently he is working to investigate the role of vaginal microbiota on reproductive health.

Affiliations and expertise

Assistant Professor, Department of Microbiology, Smt. CHM College Ulhasnagar, Mumbai, India

Life Sciences

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