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Bacterial Survival in the Hostile Environment
- 1st Edition - September 28, 2022
- Editors: Ashutosh Kumar, Shivendra Tenguria
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 8 0 6 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 7 2 2 0 - 8
Variety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the… Read more
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Request a sales quoteVariety of bacteria are present in our environment but only a few of these bacteria causes diseases in their hosts including humans. These bacteria face different stresses in the environment as well as inside the host and adapt number of strategies for their survival. In 5 parts Bacterial Survival in the Hostile Environment covers all tactics and strategies adopted by bacteria for their survival under stressed conditions and will be focused on mechanistic insights of pathogenic adaptations to host environments (acidic environment, microaerobic conditions, immune system stress, metal stress etc., modulation of host pathways by pathogens for survival, dormancy, drug tolerance and resistance, proteins for stress survival). The content also includes different adaptation mechanisms of extremophiles to extreme environment, provides a complete and globally available advance knowledge related to bacterial survival from different perspectives and reviews the knowledge gaps and future prospects in the field of microbial adaptation for sustainable development of in the field of infection biology and pharmaceutics.
- Provides in depth knowledge about pathogen biology and microbial adaptations, microbe-host interactions, impact of pathogens on host physiology, virulent factors produced by pathogens and pharmaceutical applications, mechanism of pathogenic virulent factors
- Covers all tactics and strategies adopted by bacteria for their survival under stressed conditions
- Focuses on mechanistic insights of pathogenic adaptations to host
- Includes different adaptation mechanisms of extremophiles to extreme environment
Researchers, Scientists, Microbiologists, Medical practitioners, Medical students, Biotechnologists, Bacteriologists and others in the field of infectious diseases; Industry professionals throughout the globe who aspire to work on the pathogen biology
Part 1:
1. Pathogenic adaptation to host environment
2. Adaptation to acidic environment
3. Microaerobic conditions
4. Immune system stress
5. Metal stress
Part 2: Modulation of host pathways by pathogens for adaptation/survival
6. Modulation in glycolytic flux
7. Endoplasmic reticulum stress
8. Host Mitochondria
9. Apoptosis
10. Necrosis
11. Phagosome maturation
12. Autophagy regulation
Part 3: Dormancy, Drug Tolerance and Resistance
13. Growth regulation by microbes
14. Survival and reactivation strategies of pathogens in stress through heterogeneous population generation
15. Persisters
16. Antimicrobial resistance
Part 4: Proteins for stress survival
17. Chaperones
18. Ribosome associated proteins
19. Methyltransferases
20. Proteins responsible for growth regulation of bacteria during unfavourable conditions
21. Proteins involved in biofilm
Part 5: Adaptation to Extreme Environment
22. Adaptations to Ph
23. Temperature
24. Pressure
25. Halophilic adaptations
26. Radiation adaptation
- Language: English
- Edition: 1
- Published: September 28, 2022
- Imprint: Academic Press
- Paperback ISBN: 9780323918060
- eBook ISBN: 9780323972208
AK
Ashutosh Kumar
Dr. Ashutosh Kumar is an active researcher and scientific writer in his field for over 14 years and presently working at Department of Microbiology, Tripura University (A Central University), Suryamaninagar, Agartala, Tripura, India. He received MSc and PhD degree in Biotechnology from University of Hyderabad, India. He did his postdoctoral research at TIFR-National Centre for Biological Sciences Bangalore, Indian Institute of Technology Delhi and Jamia Hamdard, New Delhi, India. He also worked as a Visiting Research Scientist at Robert Koch Institute Berlin, Germany. He has made significant contributions to the study of virulence mechanisms and strategies of survival, adaptation, and persistence of Mycobacterium tuberculosis. He was involved in identification of an enzyme from M. tuberculosis that promote biofilm formation and drugs that enhanced the potency of two current anti-tuberculosis antibiotics. He received many scholarships, awards, and fellowship during his education. He has many publications in international journals and books.
Affiliations and expertise
Tripura University (A Central University), Department of Microbiology, Suryamaninagar, Agartala, Tripura , IndiaST
Shivendra Tenguria
Dr. Tenguria is an active researcher and currently working as Project Scientist in Cedars-Sinai Medical Center, Los Angeles, CA USA. He has been actively involved in research and training of graduate and undergraduate students. He received his MSc in Life Sciences from University of Rajasthan, Jaipur and PhD in Biotechnology from University of Hyderabad, Hyderabad, India. He received his postdoctoral training from Purdue University, Indiana, USA and Cedars-Sinai Medical Center (UCLA), Los Angeles, California, USA. Currently, he is working in the area of molecular innate immunity to unravel molecular signaling mechanics for sensing danger (infectious pathogens) signals through cytosolic receptors of the innate immune system of human and mouse hosts. With his doctoral and postdoctoral fellowships and research in the area of host-microbe interactions, bacterial survival and pathogenesis, he made seminal contributions by publishing in international Jr (Cell Host-Microbe, Nature Commun, Frontiers).
Affiliations and expertise
Project Scientist, Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center (UCLA), Los Angeles, CA, United States