Life sciences print books and ebooks | Elsevier

Current Developments in Biotechnology and Bioengineering

1st Edition
February 6, 2023
Xuan-Thanh Bui + 3 more
English
Paperback
9 7 8 0 4 4 3 1 9 1 8 0 0
eBook
9 7 8 0 4 4 3 1 9 1 8 1 7

Current Developments in Biotechnology and Bioengineering: Membrane Technology for Sustainable Water and Energy Management covers a variety of advanced technologies for membrane processes, including water/wastewater treatment and reuse, membrane materials, operation and maintenance, fouling control, life cycle assessment, removal of micro/emerging pollutants, and operational cost of membrane processes. Supported by prominent editors and global contributors, this reference contains chapters on membrane treatment strategies for the current pollution of complex organic matters, nutrients, toxic substances, microplastics, membrane fouling control in different water resources, and reusing water resources through promising separation technologies, including reverse osmosis, forward osmosis, and membrane distillation.

Aeromicrobiology

1st Edition
February 4, 2023
Mathew Olusoji Ilori + 2 more
English
Paperback
9 7 8 0 3 2 3 9 6 1 2 2 6
eBook
9 7 8 0 3 2 3 9 5 8 3 1 8

Aeromicrobiology provides a detailed and systematic analysis of the microbial communities and toxins collectively called bioaerosols that can be found in air. It provides information on the basics of Aeromicrobiology, the fate and transport of microorganisms in air, and the fundamental differences between intramural and extramural Aeromicrobiology. Leaning heavily on the current state of science, detailed information on the sampling and analysis of bioaerosol samples is provided. Subsequent chapters comprehensively discuss various airborne microbial groups and toxins, while the final chapter is dedicated to bioaerosol control strategies, biosafety, and biosecurity. There are limited resources on Aeromicrobiology. In rare instances where there are resources on Aeromicrobiology, they are often restricted to chapters in books or even supplementary materials. The emergence of new airborne pathogens, the aerosolization of microorganisms hitherto believed not to be airborne, and the proliferation of technologies for sampling, analysis, and control of bioaerosols makes it imperative for this title, which streamlines and succinctly presents the new body of knowledge in the field.

Basic Biotechniques for Bioprocess and Bioentrepreneurship

1st Edition
February 3, 2023
Arvind Kumar Bhatt + 2 more
English
Paperback
9 7 8 0 1 2 8 1 6 1 0 9 8
eBook
9 7 8 0 1 2 8 1 6 1 1 0 4

Basic Biotechniques for Bioprocess and Bioentrepreneurship deals with the entire field of industrial biotechnology, starting from the basic laboratory techniques to scale-up, process development, demonstration, and finally its commercialization. The book compiles currently scattered materials on this topic and updates this information based on practical experience and requirements. The book will be an ideal source for new entrepreneurs who wish to start their own commercial units.

Novel Methods and Pathways in Cancer Glycobiology Research

1st Edition
Volume 157
February 2, 2023
Charles J Dimitroff + 1 more
English
Hardback
9 7 8 0 3 2 3 9 9 1 7 7 3
eBook
9 7 8 0 3 2 3 9 9 1 7 8 0

Cancer glycobiology is a blazing hot area of cancer research with aberrant post-translational glycosylations on lipids and proteins considered critical for cancer development and metastasis. The NIH/NCI Alliance of Glycobiologists for Cancer Research is a consortium of (10) tumor glycobiology laboratories funded to investigate how cancer-associated glycans (CAG) impact the development and metastasis of cancer. The hope of this momentous effort is to discover CAGs for use as novel biomarkers to detect early-stage cancer or its aggressive behavior or, alternatively, as novel molecular targets with the promise of a curative approach to cancer therapy. The mission of the ‘Alliance’ is to study structure and function of CAGs in cancer development and to provide clinically useful biomarkers for detecting cancer early or the potential of metastasis. This charge has stimulated extensive collaborations across US and International institutions to accelerate discovery of glycan-based biomarkers to the forefront of NCI's efforts to diagnose early-stage cancer and provide curative anti-cancer therapies. The main goals of these research efforts are: 1. To identify and study how cancer-associated glycans functionally impact cancer growth and metastasis2. To identify cancer-associated glycans that can serve as biomarkers for the detection or progression of cancer3. To develop cancer-associated glycans as novel therapeutic targets for the treatment and cure of cancer This volume consists of (9) chapters, one from each funded laboratory, that reviews new methods and mechanisms highlighting glycoconjugates and their roles as cancer biomarkers and/or anti-cancer therapeutic targets.

Introductory Immunology

3rd Edition
February 2, 2023
Jeffrey K. Actor
English
Paperback
9 7 8 0 4 4 3 1 5 3 0 7 5
eBook
9 7 8 0 4 4 3 1 5 3 0 8 2

**Selected for Doody’s Core Titles® 2024 in Immunology**Introduc... Immunology: Basic Concepts for Interdisciplinary Applications, 3rd Edition, is a completely updated, revised, and expanded concise, conceptual approach to understanding the immune systems as a primary defense to maintain health and homeostasis. This expanded version includes the aspects of microbiology and related immune defense mechanisms important in combating disease, as well critical components related to the field of vaccine development.Immunolo... as a subject is no longer confined to the realms of "immunology" or "microbiology" studies. Indeed, the subject matter has become increasingly important to understand complex mechanisms found within a wider range of biological systems. This book aims specifically at educated audiences who do not have a deep understanding of medical, biochemical, or cellular knowledge. The overall text will present concepts that portray a comprehensive picture of the natural defenses to infectious agents as well as provide an introduction to mechanisms that lead to autoimmune dysfunction. In addition, immunological diseases will be detailed, with the goal of allowing the readers to gain sufficient knowledge to make sound choices for clinical decisions to affect treatment outcomes.This new edition expands on the existing chapters, focusing on updating the previous text. It has been expanded to include knowledge on effector mechanisms addressing components inherent within cellular responses that are either newly discovered, or missing from the previous edition. It has an extra emphasis on aspects related to mechanisms important in combating microbial agents and critical sections on how vaccines protect against pathogenic invaders to limit associated pathology.The goal is that Introductory Immunology will become the preferred provider of core knowledge in immunology to build a foundation to explore components of the human immune system that work together to confer and understand dysregulation that causes clinical diseases. This book serves as a basic platform to define therapeutic interventions by:creating appreciation for components of the human immune system to work together to confer lifelong protection;providing a core knowledge in immunology to build a foundation to explore mechanisms involved in clinical disease, and defining functional aspects of immunological terms to permit the reader easy access to comprehend specific topics;presenting introduction to complex immunological concepts in a concise and easy manner that relates to clinical disease;breaking down all of immunology into manageable, logically digestible building blocks, and providing a map to explore overlapping mechanisms of immune protective responses;providing a platform to readers without medical, biochemical, or cellular expertise to understand and appreciate how immunology controls homeostasis and protects against pathogens.

Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders

1st Edition
Volume 168
February 1, 2023
Lori Knackstedt + 1 more
English
Hardback
9 7 8 0 3 2 3 9 9 3 9 4 4
eBook
9 7 8 0 3 2 3 9 9 3 9 5 1

Metabotropic Glutamate Receptors in Psychiatric and Neurological Disorders, Volume 168 in the International Review of Neurobiology series, highlights advances in the field, with this new volume presenting interesting chapters on topics such as mGlu receptors in Parkinson’s disease, Metabotropic glutamate receptors in estradiol-mediated motivated behaviors in females, mGlu regulation of sleep, Implications for sleep disruptions in psychiatric disorders, Mechanisms of mGlu receptor trafficking; alterations by methamphetamine, Group I mGlu and cocaine seeking, The role of mGlu receptors in fear and anxiety, Regulation of Alcohol Consumption, Reward, Dependence, and Perception by Metabotropic Glutamate Receptor Signaling, and mGlu5 as a biomarker for psychiatric disorders.

Radiation Oncology and Radiotherapy Part B

1st Edition
Volume 174
January 31, 2023
Ai Sato + 3 more
English
Hardback
9 7 8 0 3 2 3 8 9 9 4 7 5
eBook
9 7 8 0 3 2 3 8 9 9 4 8 2

Radiation Oncology and Radiotherapy, Part B, Volume 174 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics including CT-assisted focal irradiation of tumors in mice, Methods to preserve correct dosimetry in small animal irradiators, Monitoring TGFbeta signaling in irradiated tumors, Cytofluorometric characterization of the lymphoid compartment of irradiated tumors, Cytofluorometric characterization of the myeloid compartment of irradiated tumors, Mass cytometry to characterize the immune infiltrate of irradiated tumors, Characterization of the immune infiltrate in irradiated mouse tumor by multiplex immunofluorescence, and much more. Other chapters cover Methods to study FOXP3+CD8+ cells in irradiated bone metastases, Luminex-based characterization of cytokine signaling by irradiated tumors, Explant-based assessment of anticancer immunity in irradiated tumors, Pipeline to characterize the TCR repertoire of irradiated tumors, Pipeline to identify tumor neoantigens exposed by radiation, and more.

Oxidative Stress Responses in Plants

1st Edition
Volume 105
January 31, 2023
Frank Van Breusegem + 1 more
English
Hardback
9 7 8 0 3 2 3 9 1 3 7 4 4
eBook
9 7 8 0 3 2 3 9 1 3 7 5 1

Oxidative Stress Response in Plants, Volume 105 covers environmental stress conditions and the accumulation of reactive oxygen species (ROS). During many stress conditions such as salt, drought, heat, and pathogen infection, changes in metabolic fluxes and alterations in enzymatic activities result in the accumulation of ROS, a major contributor to loss of growth and productivity. High levels of ROS can lead to oxidative stress which damages proteins and DNA, ultimately resulting in plant cell death. This volume provides comprehensive insights into ROS biology in plants, with a focus on plant growth and development, plant defense responses, and plant acclimation to challenging environments. On the other hand, ROS evolves into potent signaling molecules that play crucial roles in abiotic and biotic stress sensing, integration of different environmental signals, and activation of stress-response networks, thereby contributing to the establishment of improved stress resilience.

Overcoming Resistance to EGFR Inhibitors in EGFR-Mutant NSCLC

1st Edition
Volume 19
January 30, 2023
Anthony Faber
English
Hardback
9 7 8 0 1 2 8 2 2 8 3 3 3
eBook
9 7 8 0 1 2 8 2 2 8 3 4 0

Overcoming Resistance to EGFR Inhibitors in EGFR Mutant NSCLC presents updated information on how EGFR mutant lung cancers evolve to evade EGFR inhibitors, clinical strategies that identify these mechanisms, and how to implement newer therapeutic strategies to combat resistance and improve patient survival. As resistance to EGFR inhibitors is often through re-activation of MEK/ERK and PI3K pathways, or through loss of cell death responses, there is much overlap with resistance to targeted therapies in other paradigms, such as BRAF inhibitors in BRAF mutant melanoma, and HER2 inhibitors in HER2 amplified breast cancer. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field who are interested in promising treatments for lung cancer.

Joint and Bone

1st Edition
January 30, 2023
Deming Jiang + 1 more
English
Paperback
9 7 8 0 3 2 3 9 1 9 3 8 8
eBook
9 7 8 0 3 2 3 9 8 3 3 0 3

Joint and Bone: From Bench to Bedside, Volume Three, the latest release in the Stem Cell Innovation in Health and Disease series, is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. This new volume addresses the molecular players underlying iPSC formation, maintenance, and expansion and differentiation, bringing chapters that describe cutting-edge research for understanding stem cell functions in joint and bone diseases, and for developing methods to bring stem cells from bench to bedside. Each chapter includes insights ranging from the use of mouse and human organoid cultures, genetic editing in vitro and in vivo, and human iPSCs to study stem cell functions and model joint and bone diseases.

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