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    • Neurogenetics for the Practitioner

      • 1st Edition
      • April 24, 2024
      • Gregory M. Pastores
      • English
      • Paperback
        9 7 8 0 3 2 3 9 9 4 1 7 0
      • eBook
        9 7 8 0 3 2 3 9 5 8 5 9 2
      Neurogenetics for the Practitioner provides clinicians with a navigation tool to help diagnose and treat patients with neurological disorders using neurogenetics. Sections introduce the reader to an overview of genetic principles, including practical applications in relation to diagnosis and current limitations. Additional chapters highlight how to workup patients presenting with certain features, including cerebral palsy/intellectual disability, congenital muscular dystrophy, cognitive decline/dementia, peripheral neuropathy, and paroxysmal disorder. The final section explores therapeutic strategies based on genetic interventions and genetic counselling options. This internationally contributed book will become the essential reference guide for neurologists.

    • Muscle Stem Cells

      • 1st Edition
      • Volume 158
      • April 24, 2024
      • English
      • Hardback
        9 7 8 0 1 2 8 2 3 4 3 5 8
      • eBook
        9 7 8 0 1 2 8 2 3 4 3 4 1
      Muscle Stem Cells, Volume 158 in the Current Topics of Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics surrounding Muscle stem cell dysfunction in rhabdomyosarcoma and muscular dystrophy, Model systems used to study MuSC function, MuSCs in the growth and maintenance of muscle, Molecular regulation of myocyte fusion, A self-made quiescent niche of muscle stem cells, Characterization of the muscle regenerative environment, Role of microenvironment on muscle stem cell function in health, adaptation, and disease, Vascular Niche for Muscle Stem Cells, Regulation of muscle stem cell polarity in health and disease, and more.Additional chatpers cover Circadian timing of satellite cell function and muscle regeneration, Muscle stem cell activity is regulated by translational control of gene expression, Biomechanical stress in modulating MuSC function, Cross talk between cell types in regenerating muscle, Effects of the immune system on muscle regeneration, Effects of diabetes on MuSC function, and other timely topics.

    • Targeting Signaling Pathways in Solid Tumors Part A

      • 1st Edition
      • Volume 385
      • April 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 3 5 4 6 7
      • eBook
        9 7 8 0 4 4 3 2 3 5 4 7 4
      Targeting Signaling Pathways in Solid Tumors, Part A, Volume 385 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

    • Primate Anatomy

      • 4th Edition
      • April 23, 2024
      • Friderun Ankel-Simons
      • English
      • Paperback
        9 7 8 0 4 4 3 2 1 7 1 9 7
      • eBook
        9 7 8 0 4 4 3 2 1 7 1 8 0
      Primate Anatomy: Introduction to Extant Primates synthesizes the taxonomy, anatomy, physiology, and genomics of extant primates, including humans. It takes a holistic approach to describing primate skeletal, muscular, and organ structure and function, providing the tools to understanding the fundamentals and state of the science of primatology. Now in its fourth edition, this work introduces its audience to the history and objectives of the field of primatology. It enumerates and profiles extant primates before delving into detailed descriptions of primate skulls, brains, teeth, skeletons, musculature, organs, blood groups, reproduction, and development.In addition, the book highlights recent advances in primate genomics, including new genera and species assignments, and concludes with a glance at the future of the field. Written by longtime expert Friderun Ankel-Simons, this new edition effectively introduces complex biological concepts in a manner accessible to all readers. It will serve as an excellent reference for technical and non-technical audiences, including primatologists, anatomists, paleontologists, anthropologists, conservationists, and naturalists.

    • Advances in Cytometry: Applications

      • 1st Edition
      • Volume 186
      • April 23, 2024
      • English
      • Hardback
        9 7 8 0 3 2 3 9 9 4 1 9 4
      • eBook
        9 7 8 0 3 2 3 9 9 4 2 0 0
      Advances in Cytometry: Applications, Volume 176 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

    • Applications of Metagenomics

      • 1st Edition
      • April 23, 2024
      • Hrudayanath Thatoi + 2 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 8 3 9 4 5
      • eBook
        9 7 8 0 3 2 3 9 8 4 0 3 4
      Applications of Metagenomics: Agriculture, Environment, and Health examines current metagenomics methods and their applications in soil, polluted environment sites, agriculture production, and health care, with separate sections dedicated to each application area. Special attention is paid to the biotechnological study of novel microbial resources for social welfare. Beyond applications, the book discusses evolving next generation technology and techniques used for carrying out metagenomics studies, and in doing so highlights the latest research and advances in the field, along with ways to adapt these approaches for different study types across the biological sciences.Chapter topics range from metagenomics for studying root microbial communities to microbial diversity of the rhizosphere, fungal diversity, microbial biodiversity in forest environments, the human microbiome, and disease epidemiology, with one chapter dedicated to Covid-19 metagenomics.

    • Advances in Agronomy

      • 1st Edition
      • Volume 186
      • April 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 5 2 8 7
      • eBook
        9 7 8 0 4 4 3 2 9 5 2 9 4
      Advances in Agronomy, Volume 186, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

    • Introduction to Protein Mass Spectrometry

      • 2nd Edition
      • April 22, 2024
      • Pradip K. Ghosh
      • English
      • Paperback
        9 7 8 0 4 4 3 1 4 0 1 5 0
      • eBook
        9 7 8 0 4 4 3 1 3 9 2 0 8
      Introduction to Protein Mass Spectrometry, Second Edition provides a comprehensive overview of this increasingly important, yet complex, analytical technique. This book enables readers to understand how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. This new edition is fully updated to include the latest developments in the field and will feature new content covering recent progress in the areas where there have been the most exciting advances. These include PNNL’s multilevel-PCB-based SLIM realization, SLIM-Agilent QQQ field trials; employment of SLIM-IMS-cryo-IR combination in molecular structure determination; proximity-labelling mass spectrometry, and applications in neuroscience.

    • An Introduction to the Microbiome in Health and Diseases

      • 1st Edition
      • April 22, 2024
      • Charles Oluwaseun Adetunji + 3 more
      • English
      • Paperback
        9 7 8 0 3 2 3 9 1 1 9 0 0
      • eBook
        9 7 8 0 3 2 3 9 1 4 7 2 7
      The gut microbiome plays a very important role in your health. It controls digestion and has a beneficial impact on your immune system and other aspects of health. An Introduction to the Microbiome in Health and Diseases is a prelude to subsequent books on this topic which provides in-depth coverage on the microbiome from basic to clinical microbiology. This introductory volume offers an overview on the microbiome and explores the role of the human microbiome in health and disease outcomes. It examines the compositional structure and molecular approaches to microbiome characterization and identification. Additional coverage also includes an introduction to animal microbiomes, plant microbiomes, epigenetic programming, gut microbiota and the impact of diet and exercise, as well as the relationship between the microbiome and COVID-19.

    • The Covid-19 Response in New York City

      • 1st Edition
      • April 21, 2024
      • Syra S. Madad + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 7 5 5 1
      • eBook
        9 7 8 0 4 4 3 1 8 7 5 6 8
      The COVID-19 Response in New York City: Crisis Management in the Largest Public Health System provides an historical accounting of the response to the COVID-19 pandemic through the eyes of the largest public health system in the United States. The book offers a roadmap to guide healthcare systems and their providers in the event of future pandemics. Readers will learn about surge staffing and level loading, as well as tips from the ED and ICUs on how to respond to an unprecedented influx of inpatients. Written by healthcare providers who were at the epicenter of the pandemic in New York City, this book provides a sound accounting of the response to the pandemic in one of the world's largest cities.

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