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Elsevier

Books in Life sciences

  • Chemistry and Methods of Enzymes

    • 3rd Edition
    • James B. Sumner + 1 more
    • English
    Chemistry and Methods of Enzymes, Third Edition focuses on the processes, methodologies, and reactions in enzyme chemistry, as well as kinetics, nucleases, esterases, and carbohydrates. The publication first underscores the general properties of enzymes, including chemical nature, occurrence, numerical characterization of enzyme concentration, kinetics of enzyme reactions, preparation of commercial enzymes, purification and preservation of enzymes, relations of vitamins to enzymes, and zymogens and kinases. The text then takes a look at esterases and carbohydrates. Topics include pectin depolymerase, heparinase, xylanase, chitinase, dextranase, trehalase, nucleotide phosphatases, glucosulfatase, and gastric lipase. The manuscript examines nucleases, nuclein deaminases, amidases, proteolytic enzymes, and hydrases. Discussions focus on enolase, aconitase, peptidases as metalloproteins, glutaminases, aspartase, urease, adenosine deaminase, and nucleoside phosphorylase. The book also elaborates on iron and copper enzymes, dehydrogenases containing coenzymes I and II, and yellow enzymes. The text is a dependable source of data for chemists and researchers wanting to dig deeper into the chemistry and methods of enzymes.

  • Gel Electrophoresis of Proteins

    • 1st Edition
    • Michael J Dunn
    • English
    Gel Electrophoresis of Proteins focuses on the techniques, methodologies, reactions, and approaches involved in gel electrophoresis of proteins. The selection first covers steady-state gel electrophoresis systems and one-dimensional PAA-gel electrophoretic techniques to separate functional and denatured proteins. Discussions focus on affinity electrophoresis, structure and physico-chemical properties of polyacrylamide gels, moving boundary electrophoresis, isotachophoresis, fundamental steady-state electrophoresis systems, and fundamental properties of steady-state electrophoresis systems. The text then reviews conventional isoelectric focusing and immobilized pH gradients and high resolution two-dimensional polyacrylamide-gel electrophoresis. Topics include production of narrow pH gradients, extended pH gradients, polymerization kinetics, IEF in agarose matrices, titration curves, two-dimensional electrophoresis under non-denaturing conditions, and IEF in polyacrylamide matrices. The book tackles quantifying patterns from two-dimensional PAGE, protein staining and detection methods, and immunoelectrophoreti... methods. Concerns include post-electrophoretic organic protein stains, silver and enzyme stains, detection of radioactive proteins, and programming languages. The selection is highly recommended for researchers wanting to conduct studies on gel electrophoresis of proteins.

  • Chemical Pathways of Metabolism

    • 1st Edition
    • David M. Greenberg
    • English
    Chemical Pathways of Metabolism, Volume I focuses on the chemical steps involved in the metabolism of the major constituents of living organisms. The selection first elaborates on free energy and metabolism, enzymes in metabolic sequences, and glycolysis. Discussions focus on comparative biochemistry of glycolysis, enzymes of the glycolytic cycle, oxidative conversion of glucose to tetrose, transmethylation, and free energy and its determination. The manuscript then examines the tricarboxylic acid cycle and other pathways of carbohydrate metabolism. The text ponders on the biosynthesis of complex saccharides, including mechanisms of disaccharide formation, syntheses of branched polysaccharides, synthesis of levan from sucrose, and reversibility reactions by hydrolytic enzymes. The publication then elaborates on fat metabolism and acetoacetate formation and sterol and steroid metabolism. Topics include androgens, sterols, phospholipides or phosphatides, path of fat absorption, and theories of fatty acid breakdown and acetoacetate formation. The selection is a dependable reference for researchers interested in the chemical pathways of metabolism.

  • A Text - Book of Bacteriology

    • 4th Edition
    • R. W. Fairbrother
    • English
    A Textbook of Bacteriology, Fourth Edition provides information pertinent to the medical aspects of bacteriology. This book presents the importance of sulfonamide compounds in the treatment of many bacterial diseases. Organized into three parts encompassing 38 chapters, this edition begins with an overview of the salient features of the development of bacteriology. This text then explores the food requirements of the bacteria as well as the elements necessary for the synthesis of the bacterial protoplasm. Other chapters consider the numerous and complex factors involved in the reproduction of bacteria. This book discusses as well the presence of antitoxins in the serum of an individual, which is an indication of increased resistance to infection with the homologous organism. The final chapter deals with serological reactions that are most widely used, namely, agglutination, precipitation, and complement-fixation. This book is a valuable resource for medical students, physicists, bacteriologists, chemists, biochemists, and research workers.

  • Polysaccharides Peptides and Proteins

    Pharmaceutical Monographs
    • 1st Edition
    • R. T. Coutts + 1 more
    • J. B. Stenlake
    • English
    Pharmaceutical Monographs, Volume 4: Polysaccharides Peptides and Proteins provides information pertinent to a wide variety of naturally-occurring macromolecules that are either peptide, protein, or polysaccharide in nature, which are important as medicinal and pharmaceutical agents. This monograph presents the basic physical and chemical properties of polysaccharides. Organized into four chapters, this volume begins with an overview of the pharmaceutical importance of the class of compounds known as polysaccharides. This text then provides data on the structure of the polysaccharides that is obtained by isolating and identifying the product formed on hydrolysis of the molecule itself. Other chapters consider plant gums and mucilages as important medicinal and pharmaceutical products. This monograph discusses as well the autohydrolysis of gum arabic. The final chapter deals with the clinical applications of various peptide-type antibiotics. This monograph is a valuable resource for undergraduate students of pharmacy and allied subjects.

  • Proceedings of the First International Congress of Parasitology

    Roma, 21-26 September 1964
    • 1st Edition
    • Augusto Corradetti
    • English
    Proceedings of the First International Congress of Parasitology, Volume One focuses on the advancements of processes, methodologies, approaches, and reactions involved in parasitology. The selection first offers information on the role of molluscan hosts in trematode speciation; ecological analysis of the fluke fauna of birds in the USSR; digenetic trematodes of fishes as indicators of the ecology, phylogeny, and zoogeography of their hosts; and aspects of the biology of a monogenean skin parasite. The text then examines bacterial flora as one of the etiological factors influencing the establishment of parasites in the bowel of their host, responses of helminths to temperature gradients, and reservoir parasitism in helminths. The publication takes a look at the physical and biochemical characteristics of helminth glycogens; effect of insulin on glucose uptake and glycogen synthesis in the liver fluke Fasciola hepatica L.; regulation of glycogen synthesis in the liver fluke Fasciola hepatica L.; and changes in catalase activity during embryonation of Ascaris eggs and its relationship to respiration and cytochrome oxidase activity. The selection is a vital reference for researchers interested in parasitology.

  • Analytical Microbiology

    • 1st Edition
    • Frederick Kavanagh
    • English
    Analytical Microbiology focuses on the processes, methodologies, developments, and approaches involved in analytical microbiology, including microbiological, antibiotic, and amino acid assays and dilution methods. The selection first offers information on the theory of antibiotic inhibition zones, microbiological assay using large plate methods, and dilution methods of antibiotic assays. Discussions focus on serial dilution assay, requirements for accurate assay, microbiological assay of riboflavin, laws of adsorption and partition, mechanisms of antibiotic action, and biological considerations affecting the use of statistical methods. The text then ponders on the elements of photometric assaying and automation of microbiological assays. The manuscript elaborates on antibiotic substances, vitamins, and amino acids. Topics include assay organisms, validity, specificity, reliability, and calculation of results of amino acid assays, bacitracin, chloramphenicol, dihydrostreptomycin, erythromycin, neomycin, and streptomycin. The selection is a dependable reference for researchers interested in analytical microbiology.

  • Calcium Physiology

    An Advanced Treatise
    • 1st Edition
    • C. L. Comar + 1 more
    • English
    Mineral Metabolism, Volume III: Calcium Physiology focuses on the processes, reactions, and approaches involved in calcium metabolism and study of bones. The selection first underscores the measurements and models of skeletal metabolism and advances in the physical biology of bone and other hard tissues, including measurements and concepts, composition and structure of bone minerals, and dynamic studies of bone minerals. The text then takes a look at calcium and striated muscle and renal excretion of alkaline earths. Topics include physicochemical state of alkaline earth cations in plasma and urine, effects of drugs, renal diseases, calcium and contractile proteins, resting potential and action potential, calcium and muscle contraction, and coupling of excitation and energy synthesis. The book examines the aspects of intestinal absorption of calcium, with special reference to vitamin D, as well as the physiological mechanism of the intestinal absorption of calcium; effect of other nutritional and physiological factors on calcium absorption; and structure of the intestinal epithelial cell. The selection is a dependable source material for physiologists and readers interested to pursue research on calcium physiology.

  • Introduction to Modern Biochemistry

    • 2nd Edition
    • P Karlson
    • English
    Introduction to Modern Biochemistry, Second Edition focuses on the methodologies, processes, reactions, and technologies involved in biochemistry. The publication first takes a look at organic chemistry and biochemistry, amino acids, and peptides. Discussions focus on the determination of amino acid sequence in peptides, naturally occurring peptides, chemical properties, separation of amino acids, hydrocarbons as parent substances, functional groups, polymeric compounds, and reactions with biochemical significance. The text then ponders on proteins, enzymes and biocatalysis, and coenzymes. The manuscript examines nucleic acids and protein biosynthesis, metabolism of proteins, and porphyrins and hemins. Topics include chemical constitution of heme, significance and reactions of blood pigment, metabolism of aromatic amino acids, degradation to activated fatty acids, decarboxylation of amino acids, and biosynthesis and degradation of nucleotides. The text also ponders on carbon dioxide formation in the citrate cycle, fats and fat metabolism, and phosphatides, cerebrosides, and gangliosides. The book is a valuable reference for biochemists and researchers interested in the processes, approaches, and technologies involved in biochemistry.

  • Amino Acids, Proteins and Cancer Biochemistry

    • 1st Edition
    • Jesse P. Greenstein
    • John T. Edsall
    • English
    Amino Acids, Proteins, and Cancer Biochemistry focuses on the contributions of Jesse P. Greenstein to biological chemistry, including kinetics, protein mixtures, metabolism, tumors, and biosynthesis. The selection first offers information on quantitative nutritional and in vivo metabolic studies with water-soluble, chemically defined diets and internal hydrogen bonding in ribonuclease. Discussions focus on the effects of deuterium on transition temperature, kinetics of deuterium-hydrogen exchange, applications of chemically denned diets, formulation of water-soluble, chemically defined diets, and large-scale preparation of optically pure amino acids. The manuscript then examines the chromatographic evaluation of protein mixtures and observations on the activation of amino acids and biosynthesis of peptide bonds, including synthesis of phenylacetylglutamin... and benzoylglycine, studies on amino acyl adenylates, and synthesis of glutamine. The publication ponders on free amino acids and related substances in normal and neoplastic tissues; nucleic acids of normal tissues and tumors; and carbohydrate metabolism in ascites tumor and HeLa cells. Topics include carbohydrate metabolism of ascites tumor cells, comparative biochemistry of glycolysis, DNA and the genetic concept of cancer, and constancy of free amino acid patterns of tissues. The selection is a valuable source of data for biochemists and researchers interested in amino acids, proteins, and cancer biochemistry.

  • Chemical Pathways of Metabolism

    • 1st Edition
    • David M. Greenberg
    • English
    Chemical Pathways of Metabolism, Volume II focuses on the chemical processes involved in the metabolism of the essential components of living organisms, including catabolism, deamination, bonds, and synthetic processes. The selection first elaborates on nitrogen metabolism and carbon catabolism of amino acids, including deamination, urea synthesis, amino acids linked with the citric acid cycle, sulfur amino acids, and arginine and ornithine. The book then ponders on the synthetic processes involving amino acids and metabolism of sulfur-containing compounds. Discussions focus on reactions of sulfur-containing coenzymes, relationships of methionine and cysteine, desulfhydrase reaction, formation of phosphatide bases, and interconversions of glutamic acid, ornithine, and proline. The manuscript takes a look at the enzymatic syntheses of peptide bonds, purines and pyrimidines, and nucleotides and nucleosides. Topics include enzymatic splitting of coenzyme nucleotides, deamination of nucleosides and nucleotides, enzymatic synthesis of coenzyme nucleotides, purines, and pyrimidines. The selection is a valuable source of information for researchers interested in the chemical pathways of metabolism.

  • Environmental Regulation of Microbial Metabolism

    Proceedings of the Federation of European Microbiological Societies Symposium Held in Pushchino, USSR 1–7 June 1983
    • 1st Edition
    • I. S. Kulaev + 2 more
    • English
    Environmental Regulation of Microbial Metabolism contains the proceedings of the Federation of European Microbiological Societies Symposium held in Pushchino, USSR, on June 1-7, 1983. The symposium provided a forum for reviewing the environmental regulation of the metabolism of autotrophic and heterotrophic microorganisms; regulation of the biogenesis of cell walls and other structures in prokaryotic and eukaryotic microorganisms; and regulation of the secretion of macromolecules and transport of ions and solutes across microbial membranes. Comprised of 52 chapters, this book begins with an overview of some aspects of environmental regulation of microbial phosphorus metabolism, followed by a discussion on the role of covalent interconversion of enzymes in the regulation of microbial metabolism. Subsequent chapters explore the role and regulation of inorganic pyrophosphatase in bacteria; the central metabolism of pseudomonads degrading xenobiotics; the role of nickel enzymes in anaerobic metabolism; and the oxidation of aromatic compounds by microalgae. The book also considers carbon metabolism in phototrophic bacteria under different conditions of growth, along with the transport of solutes and metabolites in prokaryotes and eukaryotes. This monograph will be helpful to a wide range of specialists in the fields of biochemistry, physiology, molecular biology, and biotechnology.

  • An Introduction to Biochemistry

    • 2nd Edition
    • William Robert Fearon
    • English
    An Introduction to Biochemistry, Second Edition provides information pertinent to the fundamental aspects of biochemistry. This book presents several analytical methods, including the citrulline reaction for proteins and the diffusion test for acetone. Organized into two parts encompassing 25 chapters, this edition begins with an overview of the general composition of the organism and the chemical characteristics of the chief organic and inorganic compounds that enter into its structure. This text then examines the chemical composition of the tissues and physiological systems. Other chapters consider the occurrence and identification of several pathological constituents of urine, which presents features of biochemical interest. This book discusses as well the significance and analytical reactions of the bile acids and esters. The final chapter deals with the internal environment, which in the higher animal is represented by the blood and the cerebrospinal and other tissue fluids. This book is a valuable resource for biochemists.

  • The Biochemistry and Physiology of Bone

    • 1st Edition
    • Geoffrey H. Bourne
    • English
    The Biochemistry and Physiology of Bone focuses on the advancements of techniques, methodologies, and approaches involved in bone studies, including general anatomy, tissues, collagen fibers, and calcification. The selection first offers information on the general anatomy and histology of bone and bone as a mechanical engineering problem. Topics include strength of healing fractures, nervous influences on bone, growth of the skull, bone strength, primary constituents of bony tissue, and types and organization of bony tissue. The text then elaborates on the ground substance of connective tissue and cartilage, organic matrix of bone, and collagen fibers of connective tissue. The publication takes a look at the ultrastructure and distribution of mineral salts in bone tissue, osteoblast, and osteoclast. Discussions focus on microscopical appearances, integration of morphological and histochemical studies, cytochemistry, distribution of inorganic salts in bone tissue, relation of collagen to its environment, and structure of collagen fibers. The publication also examines pathological calcification, effects of radiation on bone, parathyroid glands and bone, and anterior pituitary regulation of skeletal development. The selection is a dependable source of data for researchers interested in the biochemistry and physiology of bone.

  • Mammalian Protein Metabolism

    Volume II
    • 1st Edition
    • H. N. Munro + 1 more
    • English
    Mammalian Protein Metabolism, Volume II focuses on the processes, methodologies, and reactions involved in mammalian protein metabolism, including toxicities, amino acid imbalance, and digestion and absorption. The selection first offers information on the nutritive value of dietary proteins, amino acid toxicities and imbalances, and protein requirements. Discussions focus on the protein requirements of adults, infants, and children, amino acid requirements, protein requirements in pregnancy, amino acid imbalance, mixed diets, and nutritive value and maintenance. The text then ponders on protein metabolism and requirements in pregnancy and lactation and protein metabolism and requirements in the newborn. The publication examines protein metabolism and requirements in the elderly; anomalies of amino acid metabolism; and physical injury and its effects on protein metabolism. Topics include general disturbance of protein metabolism following physical injury, nature of inflammatory reaction, acquired disturbances of amino acid metabolism, plasma proteins, nitrogen balance, digestion and absorption, and protein withdrawal. The text then elaborates on protein metabolism and tumor growth, experimental protein-calorie deficiency, and the clinical aspects of protein malnutrition. The selection is a dependable source of data for researchers interested in mammalian protein metabolism.

  • Chemical Determinations

    • 1st Edition
    • Ralph I. Dorfman
    • English
    Chemical Determinations is a collection of papers that discusses chemical methods used in hormone investigation. One paper explains the physicochemical procedures used to separate estrogens from interfering material which leads to the possible determination of small amounts of hormones in biological fluids. One approach is through simpler methods for routine use, designed principally for the determination of estrogens in urine and in plasma. Another way is through more elaborate methods, designed to establish the presence and identity of various estrogens in small numbers of biological samples. Another paper explains the methods for the analysis of 17-ketosteroids of blood and urine, and a method for the assay of testosterone in plasma which correlates with the state of virilism of an individual. One paper describes the techniques utilized for extraction, preliminary purification, isolation, and quantitative estimation of progesterone. Another paper reviews the occurrence of pregnanetriolone (an inactive urinary metabolite), the significance of its estimation as an aid in differential diagnosis, the methods of estimation, as well as the metabolic pathways leading to the excretion of pregnanetriolone and related steroids. The collection is suitable for researchers, scientists, medical practitioners, or academicians involved in endocrinology, metabolism, and bio-research.

  • Immunological Methods

    Volume III
    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods, Volume III provides information pertinent to the fundamental aspects of immunological methods. This book presents recombinant DNA technology as applied to immunology. Organized into 25 chapters, this volume begins with an overview of the major histocompatibility complex. This text then examines the use of monoclonal antibodies in the identification of lymphocyte membrane antigens and explains the use of monoclonal antibodies in histocompatibility typing. Other chapters consider the methods in two-dimensional electrophoretic analysis of proteins and another to lymphokines that support B cells. This book discusses as well the production and expansion of cloned B and T cell lines and hybridomas. The final chapter deals with the sophisticated methodology used with particular animal species, namely, birds, sheep, and amphibians to probe specific immunological questions. This book is a valuable resource for immunologists and investigators with extensive experience in using immunological methods. Protein chemists and biologists will also find this book useful.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske
    • English
    The Alkaloids: Chemistry and Physiology, Volume VI: Supplement to Volumes I and II updates the chemistry of the alkaloids by linking developments to the content of earlier volumes. This book discusses the taxonomic position of the alkaloids in plants, external factors governing alkaloid formation, pyrrolidine alkaloids, and structure of the necines. The alkaloids of the pomegranate root bark, alkaloids of Sedum spp, structure of dioscorine, and reactions of morphine and codeine are also elaborated. This publication likewise covers the chemistry of colchicine, alkaloids derived from dibenzofuran, and biological effects of the amaryllidaceae alkaloids. This volume is a good reference for chemists and specialists conducting work on alkaloids.

  • Hormonal Proteins and Peptides

    Volume II
    • 1st Edition
    • Choh Hao Li
    • English
    Hormonal Proteins and Peptides, Volume II reviews extensively the knowledge on the biology and chemistry of the protein and peptide hormones. This book presents the structures of the various protein and peptide hormones. Organized into three chapters, this volume begins with an overview of the various aspects of the structure and function of adrenocorticotropin hormone (ACTH) with reference to the ability to stimulate the adrenal gland of the rat, amphibian melanophores, and adipose tissues of the rat and rabbit. This text then reviews the isolation, purification, and elucidation of the amino acid sequence of corticotropins from various species. Other chapters consider the structures of porcine and human ACTH. This book discusses as well the working hypothesis for studies on the secondary-tertiary structure of peptide hormones. The final chapter deals with the abbreviations used for amino acids and protecting groups. This book is a valuable resource for peptide chemists, biologists, biochemists, and research workers.

  • Biochemistry and Physiology of Protozoa

    • 1st Edition
    • André Lwoff
    • English
    Biochemistry and Physiology of Protozoa, Volume I focuses on the chemical and physiological features of Protozoa, including nutrition, metabolism, and growth of phytoflagellates, Trypanosomidae and Bodonidae, biochemistry of ciliates and Plasmodium, and the influence of antimalarials. The selection first offers information on the biochemistry of Protozoa and phytoflagellates, including sexuality in Chlamydomonas, growth factors and chemical asepsis, descriptive chemistry and phylogenetic relationships, evolutionary aspects of photosynthesis, nutrition and biochemistry of Protozoa, and the biochemical evolution of Protozoa. The text then ponders on the nutrition of parasitic flagellates and metabolism of Trypanosomidae and Bodonidae. The publication takes a look at the nutrition of parasitic amebae, biochemistry of Plasmodium and the influence of antimalarials, and the biochemistry of ciliates in pure culture. Topics include carbon metabolism and respiration, nitrogen metabolism, antimalarial compounds and their influence on the metabolism of malarial parasites, metabolism of malarial parasites, and nutrition of the dysentery ameba, Entamoeba histolytica. The selection is a valuable reference for cytologists, geneticists, and pathologists interested in the biochemistry and physiology of protozoa.

  • The Peptides

    Volume II Synthesis, Occurrence, and Action of Biologically Active Polypeptides
    • 1st Edition
    • Eberhard Schröder + 1 more
    • English
    The Peptides, Volume II: Synthesis, Occurrence, and Action of Biologically Active Polypeptides focuses on the synthesis of biologically active polypeptides and analogues. The publication first offers information on linear peptides and heterodetic cyclic peptides. Discussions focus on depsipeptides, polycyclic and monocyclic disulfides, naturally occurring biologically active peptides, glandular hormones, and tissue hormones. The text then ponders on homodetic cyclic peptides, including homodetic cyclic homomeric peptide antibiotics, polycyclic biologically active polypeptides, and homodetic cyclic heteromeric peptide antibiotics. The manuscript takes a look at the problems related with the synthesis of biologically active polypeptides, giving emphasis to a number of movements which elaborated on the matter and the advancements of preparative techniques and approaches leading to the purification of intermediates and end products. The publication is a valuable reference for researchers interested in the occurrence, synthesis, and action of biologically active polypeptides.

  • Oxygenases

    • 1st Edition
    • Osamu Hayaishi
    • English
    Oxygenases focuses on the processes, methodologies, technologies, and approaches involved in oxygenases, including its distribution in animals, plants, and microorganisms and its role in the metabolism of aromatic, cyclic, and aliphatic compounds. The selection first offers information on the history and scope of oxygenases, methodology of oxygen isotopes, and phenolytic oxygenases. Discussions focus on the separation and purification of compounds for isotopic analysis; general properties and mechanisms of action of oxygenases; physiological significance of oxygenases; dehydrogenases, oxidases, and oxygenases; and problems and restrictions in the use of oxygen-18. The text then examines aromatic hydroxylations, oxygenases in lipid and steroid metabolism, and bacterial oxidation of hydrocarbons. Topics include anaerobic oxidation of alkanes, involvement of molecular oxygen in hydrocarbon utilization, steroid hydroxylation mechanisms, oxygenases in the biosynthesis of steroid hormones, conversion of dopamine to norepinephrine, and general discussion of mechanism of aerobic hydroxylation reactions. The selection is a valuable reference for researchers interested in the process of oxygenases.

  • Basic Immunology

    • 1st Edition
    • E. R. Gold + 1 more
    • English
    Basic Immunology focuses on substances that take part in serological reactions, including antigens, antibodies, and the physicochemical nature of immunological reactions. The selection first elaborates on the basic notions of immunity, antigens, immunoglobulins, and the production of antibody. Discussions focus on factors which increase the immune response, production of antibody, biological properties of immunoglobulins, evolution and control of immunoglobulin structure, antigenicity, specific immunity, and resistance. The text then takes a look at the complement system, antigen-antibody reactions, and immediate hypersensitivity. The book ponders on cell-mediated immunity and delayed hypersensitivity, transplantation immunology, and tumor immunology. Topics include production of immunity to neoplasms, immunological aspects of carcinogenesis and growth of established tumors, immunotherapy for experimental neoplasms, donor selection in human-organ transplantation, elicitation of delayed hypersensitivity, and the role of humoral factors in the transfer of delayed hypersensitivity. The selection is a valuable reference for medicine students and researchers interested in basic immunology.

  • Biochemistry of Glucuronic Acid

    • 1st Edition
    • Neal E. Artz + 1 more
    • English
    Biochemistry of Glucuronic Acid provides a comprehensive study of the metabolic importance of glucoronic acid. This book presents the physiological role of glucoronic acid as a detoxifying agent. Organized into four chapters, this book begins with an overview of the naphthoresorcinol test, which is the most accurate colorimetric method for the determination of glucoronic acid. This text then explores the occurrence of glucoronic acid, which is found in many plant gums, in oxycellulose, as well as in conjugated form in low concentrations in normal blood and urine. Other chapters consider the mechanisms for the formation of glucoronic acid in the body. The final chapter deals with detoxication as any chemical change occurring in the body that brings about the conversion of a foreign compound of known structure to a derivative that is excreted in the urine. This book is a valuable resource for biochemists.

  • Cis-Trans Isomeric Carotenoids, Vitamins A and Arylpolyenes

    • 1st Edition
    • L. Zechmeister
    • English
    Cis-Trans Isomeric Carotenoids, Vitamins A, and Arylpolyenes focuses on the reactions, characteristics, and properties of cis-trans isomeric carotenoids, vitamins A, and arylpolyenes. The publication first takes a look at carotenoids, number, types, and properties of cis carotenoids, and cis-trans isomerism and UV spectra. Discussions focus on simple theoretical interpretation of spectral phenomena, spectra at extremely low temperatures, relative stabilities, melting points, rotatory power, and historical remarks on the stereoisomerism of polyenes. The text then ponders on the preparation of cis carotenoids by direct rearrangement of the all-trans form and total synthesis and naturally occurring cis and polycis carotenoids. The manuscript examines some general remarks on configurational assignments, configurational assignments in certain stereoisomeric sets, and lower-molecular weight carotenoid-carboxyli... acids. Topics include bixin set, stereoisomeric sets with two aromatic terminal groups, stereoisomeric sets with one hydroaromatic and one aliphatic terminal group, configuration and infrared spectrum, and stereoisomeric types. The manuscript also elaborates on vitamins A and retinenes, cumulenes with aromatic terminal groups, and polyene azines. The publication is a dependable source of information for researchers interested in cis-trans isomeric carotenoids, vitamins A, and arylpolyenes.

  • Immunology in Clinical Medicine

    • 3rd Edition
    • J. L. Turk
    • English
    Immunology in Clinical Medicine is an introduction to immunology in clinical medicine, with emphasis on immunological concepts underlying disease processes. The effect of drugs known to suppress immunological processes are considered especially in relation to whether they operate by really suppressing immunological processes or whether they have other actions. Comprised of 17 chapters, this book begins with an overview of the nature of the immune response, followed by a discussion on reactionS in the tissues mediated by humoral antibodies. The reader is then introduced to reactions in the tissues caused by the cell-mediated immune response; immunological processes in infective diseases; and the concept of autoimmunity and its relation to disease. Subsequent chapters focus on the immunology of diseases such as cancer, skin diseases, connective tissue diseases, and diseases of the intestinal tract, respiratory tract, liver, and amyloidosis. The final chapter is devoted to the role of the clinical immunologist in patient care and therapy. This monograph is intended for students and practitioners of clinical medicine.

  • Differential Oral Diagnosis in Systemic Disease

    • 1st Edition
    • Alvin F. Gardner
    • English
    Differential Oral Diagnosis in Systemic Disease focuses on oral manifestations of systemic disease, including glomerulonephritis, hepatitis, cirrhosis, and lung infection. The publication first takes a look at the diseases of the heart and blood-vessels, respiratory tract, and genito-urinary system correlated to the oral tissues. Topics include metastatic neoplasms from the kidney to the oral region, malignant neoplasms of the kidney, glomerulonephritis, metastases of neoplasms of the lungs to the oral cavity, dental sepsis and lung infection, thrombophlebitis, and congenital anomalies of the heart. The manuscript ponders on the diseases of the liver and biliary tract and gastro-intestinal tract correlated to the oral tissues and diseases of the hematopoietic system. Discussions focus on oral manifestations of alterations in white blood-cells and red blood-cells, oral manifestations of diseases of the gastro-intestinal tract, diseases of the stomach and the intestine, cirrhosis of the liver, correlation of fatty change of the liver to dentistry, and transmission of viral hepatitis correlated to dentistry. The book is a dependable reference for dentists and physicians wanting to study the oral manifestations of systemic disease.

  • Evolving Genes and Proteins

    A Symposium Held at the Institute of Microbiology of Rutgers • the State University with Support from the National Science Foundation
    • 1st Edition
    • Vernon Bryson + 1 more
    • English
    Evolving Genes and Proteins covers the proceedings of the "Evolving Genes and Proteins" symposium, held at the Institute of Microbiology of Rutgers, The State University on September 17 and 18, 1964, with support from the National Science Foundation. The book focuses on the structural and functional features of proteins and nucleic acids. The selection first offers information on lysine biosynthesis and evolution, lipid patterns in the evolution of organisms, and evolution of heme and chlorophyll. Discussions focus on the evolution of the genes of the porphyrin biosynthetic chain, polyunsaturated fatty acids in plants and animals, and diagnostic radiocarbon tracers. The text then examines evolutionary divergence and convergence in proteins; evolution of hemoglobin in primates; and constancy and variability of protein structure in respiratory and viral proteins. The publication takes a look at the comparative aspects of the structure and function of phosphoglucomutase, evolution of dehydrogenases, and enzymatic homology and analogy in phylogeny. The text also ponders on the evolution of an enzyme, role of mutations in evolution, enzyme catalysis and color of light in bioluminescent reactions, and evolution of the lactose utilization gene system in enteric bacteria. The selection is a valuable reference for microbiologists and readers interested in the study of genes and proteins.

  • Immunological Influence on Human Fertility

    Proceedings of the Workshop on Fertility in Human Reproduction, University of Newcastle, Australia, July 11-13, 1977
    • 1st Edition
    • Barry Boettcher
    • English
    Immunological Influence on Human Fertility covers the proceedings of the Workshop on Fertility in Human Reproduction, held at the Department of Biological Science, University of Newcastle, Australia on July 11 -13, 1977. The book focuses on topics on the immunological control of human and animal fertility. The selection first discusses the zona pellucida as a possible target in immunocontraception, immunological aspects of vasectomy, and the clinical significance of antibodies to spermatozoa. Topics include performance and significance of the SCMC-test, antibodies and fertility after vasovasostomy, vasectomy and the blood-testis barrier, cellular immune response, active and passive immunization, and tissue and species specificity. The book then tackles the nature of the barrier to autoimmunity in the excurrent ducts of the mammalian testis, immune activities of the male and female reproductive tracts, and isolation of spermatozoal antigens. The manuscript examines the immunological capacity of the male genital tract, clinical significance of antibodies to antigens of the reproductive tract, immunological aspects of vasectomy, and antigens of human trophoblasts. The text also takes a look at the immunological and anti-tumor effects of orchidectomy, immune infertility and approaches to treatment, natural insemination as an immune phenomenon, and modified seminal plasma antigens and subfertility. The selection is a valuable source of information for researchers wanting to study the immunological control of human and animal fertility.

  • The Anatomy of the Developing Lung

    • 1st Edition
    • John Emery
    • English
    The Anatomy of the Developing Lung provides an introduction to the anatomical studies of the lung. This book discusses the structure of the developing fetal lung and reviews the knowledge on the development of goblet cells and glands in the trachea-bronchial tree in man. Organized into 11 chapters, this book begins with an overview of the general pattern of growth of the fetal lung and the development of the alveoli. This text then examines the important ultrastructural characteristics of the mature lung and explains the changes in the muscle of the blood vessels around birth. Other chapters consider the role and development of cartilage and examine the relationship between collagen and elastic tissue. This book discusses as well the general function of mature collagen. The final chapter deals with the measurement of postnatal lung weight. This book is a valuable resource for pediatricians, histologists, physiologists, clinicians, pathologists, and research workers.

  • Immunocytochemistry

    Practical Applications in Pathology and Biology
    • 1st Edition
    • Julia M. Polak + 1 more
    • English
    Immunocytochemistry: Practical Applications in Pathology and Biology focuses on the processes, principles, methodologies, and approaches involved in the applications of immunocytochemistry in pathology and biology. The selection first takes a look at the development and scope of immunocytochemistry; techniques and practice used in immunocytochemistry; and raising and testing antibodies for immunocytochemistry. The book then ponders on raising antibodies to small peptides, use of semithin frozen sections in immunocytochemistry, and colloidal gold probes in immunocytochemistry. Discussions focus on the production of gold probes, localization of mouse serum albumin in the mammary gland, immunogens and the immune response, production of antisera, and antibody specificity in immunocytochemistry. The publication takes a look at double immunoenzymatic labelling, lectin histochemistry, immunocytochemical localization of noradrenaline, adrenaline, and serotonin, and immunocytochemistry of cell and tissue cultures. Immunocytochemistry in endocrine pathology and indirect immunofluorescence in the study and diagnosis of organ-specific autoimmune diseases are also discussed. The selection is a dependable source of information for researchers interested the practical applications of immunocytochemistry in pathology and biology.

  • Illustrated Guide for Theatre Nurses

    • 1st Edition
    • A. Marjorie Matthias + 2 more
    • English
    Illustrated Guide for Theatre Nurses provides practical instruction on how to perform correctly the many duties of a nurse. It presents the various procedures that are described in a series of photographs. This text begins with a series of photographs showing how the nurse should carry out her duties in the operating room. It then demonstrates the fundamental principles that underlie all modern operating techniques. This book is a valuable resource for nurses, technicians, student nurses, medical students, and clinical instructors.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske
    • English
    The Alkaloids: Chemistry and Physiology, Volume V: Pharmacology deals with the chemistry and pharmacology of the alkaloids. This book discusses the general pharmacology of morphine, cryptopine-like compounds, toad poisons, and respiratory stimulants. The appraisal of the utility of alkaloids as antimalarials, uterine stimulants, metabolism of cocaine, and optical isomerism-activity relationship are also elaborated. This publication likewise covers the parasympathetic blocking agents as mydriatics, methods of measuring mydriatic activity, alkaloids exhibiting curariform activity, and minor alkaloids of unknown structure. Other topics include the fate of morphine, tropane group, factors affecting cocaine anesthesia, and sympathomimetic mydriatics. This volume is intended for chemists and pharmacologists concerned with alkaloids.

  • Immunological and Blood Products

    Pharmaceutical Monographs
    • 1st Edition
    • Mary Dawson + 1 more
    • J. B. Stenlake
    • English
    Pharmaceutical Monographs, Volume 5: Immunological and Blood Products provides an introduction to immunology and immunological products. This monograph describes various tissue culture techniques, which are important both in the preparation and standardization of certain immunological products. Organized into two parts encompassing 13 chapters, this volume begins with an overview of the types of immunity. This text then examines the substances which when introduced parenterally into the tissues, stimulates the production of an antibody. Other chapters consider antibodies as substances appearing in the blood or body fluids in response to the stimulus provided by the introduction of an antigen. This monograph discusses as well the preparations capable of stimulating active immunity. The final chapter deals with the causation of hemolytic disease of the newborn. This monograph is a valuable resource for medical students as well as undergraduate students of pharmacy. Students of veterinary medicine will also find this book extremely useful.

  • Fertilization

    Comparative Morphology, Biochemistry, and Immunology
    • 1st Edition
    • Charles B. Metz + 1 more
    • English
    Fertilization: Comparative Morphology, Biochemistry, and Immunology, Volume I focuses on the many aspects of the physiological mechanisms of fertilization in different forms of life. The selection first tackles the problems and procedures of comparative gametology and syngamy and sperm motility. Discussions focus on the morphology of cilia and flagella, extraneous chemical and physical factors, motility in male and female reproductive tests, problems of the quantitative and qualitative control of fertility, and patterns of reproduction. The text then ponders on sperm metabolism and mechanisms of gametic approach in plants. The manuscript takes a look at gamete surface components and their role in fertilization, acrosome reaction and lysins, and membrane fusion in relation to sperm-egg association. Topics include gametic association, acrosome formation during spermiogenesis, fine-structure studies of acrosomal changes, specificity of fertilization, and amphibian fertilization. The book also examines the activation of the egg and parthenogenesis in vertebrates. The selection is a valuable reference for readers interested in the processes involved in fertilization.

  • The Status of Enzymes and Hormones in Therapy

    • 1st Edition
    • G. F. Walker
    • English
    The Status of Enzymes and Hormones in Therapy reviews the status of therapy with enzymes and hormones, with emphasis on endocrine preparations of thyroid and parathyroid, ovarian hormones, pituitary hormones, thymus, and suprarenal glands as well as testis, spleen, brain and muscle tissue, and other organs such as the bile and placenta. The landmarks used are the British Pharmacopoeia, the British Pharmaceutical Codex published in September 1934, and clinical records selected from the literature. Comprised of two chapters, this book begins with an introduction to endocrine therapy, focusing on the need for clinicians to properly assess the clinical potency of the remedies they use based on considerations such as whether they clearly recognize in their patient a hormonic lack, or whether the preparation is smoothly active when administered by the route they propose. The second chapter deals with various endocrine preparations, including commercial preparations of thyroid; ovarian and pituitary hormones; stomach; pancreas; bone marrow; hemoglobin; and pineal, mammary, lymphatic, and prostate glands. This monograph is intended for clinicians interested in the therapeutic uses of enzymes and hormones.

  • Protein and Amino Acid Requirements of Mammals

    • 1st Edition
    • Anthony A. Albanese
    • English
    Protein and Amino Acid Requirements of Mammals focuses on the determination of the protein and amino acid requirements of various mammals, including man in particular. The selection first offers information on some species and age differences in amino acid requirements and the methods of measuring the nutritive value of protein hydrolysates and amino acid mixtures. Discussions focus on assay methods based on protein regeneration; specificity of amino acid requirements; amino acid requirements for nitrogen equilibrium in the adult; and composition of tissue proteins and amino acid requirements for growth. The text then examines the laboratory evaluation of amino acid mixtures and protein hydrolysates and dietary proteins and synthesis of tissue proteins. Topics include role of dietary proteins in the hypertrophy of gonads, effect of dietary proteins on repletion of liver proteins, and effect of dietary proteins on the synthesis of plasma proteins. The publication examines the protein and amino acid requirements of man, including qualitative amino acid requirements of various species, growth and protein and amino acid needs, and metabolic interactions of essential and nonessential amino acids. The selection is a dependable reference for researchers interested in the determination of the protein and amino acid requirements of mammals, including man.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske + 1 more
    • English
    The Alkaloids: Chemistry and Physiology, Volume IV contains an account of the chemistry and biosynthesis of the various classes of isoquinolines. This book discusses the extraction and separation of the anhalonium alkaloids, other natural simple isoquinolines, and anhalonium isoquinolines. The location of the alkaloids in tissues of the cacti, monophenolic bases of the laudanosine type, and extraction of cactus alkaloids are elaborated in detail. This text also describes the several types of alkaloids such as protoberberine, aporphine, protopine, phthalideisoquinolin... and bisbenzylisoquinolin... The cularine, a-naphthaphenanthrid... erythrophleum, aconitum, and delphinium alkaloids are likewise included. This publication is recommended for chemists, specialists, and students interested in isoquinolines.

  • Immunological Methods

    Volume IV
    • 1st Edition
    • Ivan Lefkovits + 1 more
    • English
    Immunological Methods, Volume IV provides information pertinent to the methods in immunological research. This book focuses on cells, clones, and cell lines, as well as on their components and secreted products. Organized into 21 chapters, this volume begins with an overview of hybridoma methodology as the most celebrated immunological method. This text then discusses cell fusion, hybridoma technology, and everything related to monoclonal antibodies. Other chapters consider another molecular biology method, which describes the procedure required for establishing a partitioned cDNA-library. This book provides as well a comprehensive analysis of mRNA populations in which every messenger species appears as a distinct element, and so provides accurate answers to questions concerning genetic complexity. The final chapter provides an example of how transgenic mice can be used to study the development of T cell repertoires. This book is a valuable resource for cell biologists, scientists, immunologists, and research workers.

  • Mammalian Protein Metabolism

    Volume I
    • 1st Edition
    • H. N. Munro + 1 more
    • English
    Mammalian Protein Metabolism, Volume I focuses on the processes, methodologies, biosynthesis, protein formation, and reactions involved in mammalian protein metabolism. The selection first elaborates on the origin and growth of concepts of protein metabolism, including the development of nitrogen balance as a technique for the study of protein metabolism; identification of proteins as a chemical class; discovery of nitrogen and its biological consequences; and recognition of the importance of nitrogenous compounds. The text then examines protein digestion and absorption in nonruminants and digestion and absorption of nitrogenous compounds in ruminants. Topics include passage of nitrogenous compounds from the rumen; utilization of nitrogenous compounds in the rumen; and endogenous nitrogen entering the reticulum and rumen. The book examines free amino acids and peptides in tissues, metabolic fate of amino acids, protein biosynthesis in mammalian tissues, and metabolism of plasma proteins. Discussions focus on the distribution of proteins between plasma and lymph, interpretation of plasma radioactivities, amino acid activating enzymes, ribosomes and protein synthesis, pathways of amino acid degradation, and synthesis of urea. The selection is a dependable source of data for researchers interested in mammalian protein metabolism.

  • Biochemistry of Lipids

    Biochemistry Series One
    • 1st Edition
    • T. W. Goodwin
    • English
    MTP International Review of Science: Biochemistry Series One, Volume 4: Biochemistry of Lipids focuses on the processes, methodologies, reactions, and approaches involved in the biochemistry of lipids. The selection first elaborates on the enzymes of sterol biosynthesis and lipids in glycan biosynthesis. Topics cover polyprenols and glycan biosynthesis in green plants; polyprenols and glycan biosynthesis in yeasts and fungi; undecaprenol and bacterial wall glycan biosynthesis; methods of investigating particle-bound enzymes of sterol biosynthesis; and relationship of the multi-enzymic synthesis of cholesterol to other microsomal processes. The text then elaborates on the biosynthesis of saturated fatty acids, dynamic role of lipids in the nervous system, and biosynthesis of unsaturated fatty acids. Discussions focus on anaerobic pathway of monoenoic fatty acid biosynthesis, exchange of brain lipids, lipids and transmission in the nervous system, fatty acid synthetase, and lipid distribution within the nervous system. The manuscript examines halogenated sulphatides and prostaglandins, including identification of prostaglandins in organs and body fluids, estimation of prostaglandins, and occurrence of halosulphatides in membranes. The selection is a valuable reference for researchers interested in the biochemistry of lipids.

  • Vegetative Physiology and Biochemistry

    The Eye
    • 1st Edition
    • Hugh Davson
    • English
    The Eye: Volume 1, Vegetative Physiology and Biochemistry is a compendium of papers that describes the physiology of the eye, particularly its gross anatomy and embryology including its intra-ocular fluids, the intra-ocular pressure, the vitreous body, lens, cornea, and sciera. Several papers review the eyeball, the protective apparatus of the eye, the structure of the tissue in relation to the intra-ocular fluids, and the flow of aqueous humor. Several methods can be used to measure the intra-ocular pressure such as the manometric method and the tonometer. Giles (1959) reports that tonometer measurements in the newborn are within the normal adult range. One paper notes that in man, liquefaction of the vitreous body (the clear jelly-like structure which fills the space between retina and lens,) which is caused by dissolution of the fibrous network, is never repaired. This suggests that new fibers are either not formed or are formed in insufficient amounts. Another paper examines the relationship between pressure in the eye vessels and eye tension. Investigators and researches in the fields of physiology, psychology, ophthalmology, and in all branches of ocular physiology will find the compendium very rewarding.

  • The Kidney

    Morphology, Biochemistry, Physiology
    • 1st Edition
    • Charles Rouiller + 1 more
    • English
    The Kidney: Morphology, Biochemistry, Physiology, Volume I focuses on present knowledge about the kidney under normal and pathological conditions, as manifested by morphological, biochemical, and physiological studies. The selection first takes a look at the embryonic kidney and the general anatomy and histology of the kidney. Discussions focus on the morphogenesis of transient kidneys, physiology of the fetal nephron, renal malformations, vascularization of the kidney, uriniferous tubules, and innervation of the kidney. The book then examines the histochemistry of the kidney and ultrastructure of the normal and pathological glomerulus. The manuscript ponders on electron microscopy of uriniferous tubules and ultrastructural pathology of tubules and interstitial tissue. Topics include proximal convoluted tubule, basement membranes of the tubules, capillaries, interstitial cells, morphology and functions of the tubular epithelium, fixation and preparation of tissues for electron microscopy, and structure of the submammalian vertebrate tubule. The selection is highly recommended for morphologists, biochemists, physiologists, pathologists, pharmacologists, and clinicians.

  • Carbohydrate Metabolism

    And Its Disorders
    • 1st Edition
    • F. Dickens + 2 more
    • English
    Carbohydrate Metabolism and its Disorders focuses on the processes and methodologies involved in carbohydrate metabolism, including detection of diabetes, hypoglycemic syndromes, cardiovascular diseases, and atherosclerosis. The selection first takes a look at the detection of diabetes in man, hormonal disturbances in diabetes, and hypoglycemia. Topics include indications for testing for diabetes, reasons for early detection, testing for diabetes with tolbutamide, glucagon, corticosteroids, and hypoglycemic syndromes. The book also ponders on the physiological aspects of carbohydrate metabolism in the fetus and newborn and glycogen-storage diseases. The publication examines dietary intake of carbohydrate in relation to diabetes and atherosclerosis and glucose tolerance in ischemic cardiovascular disease. Discussions focus on epidemiological studies of diabetes and atherosclerosis, overt diabetes mellitus, and effects of selection, age, obesity, and other factors. The book also identifies disturbances of the digestion and absorption of carbohydrates; insulin antagonists and disturbances in carbohydrate metabolism; and glycosaminoglycans in joint disorders. The selection is a valuable reference for readers interested in carbohydrate metabolism.

  • Metabolic Pathways

    Second Edition of Chemical Pathways of Metabolism
    • 2nd Edition
    • David M. Greenberg
    • English
    Metabolic Pathways, Volume II focuses on the metabolism, biosynthesis, and catabolism of amino acids. The selection first offers information on nitrogen and carbon metabolism of amino acids. Discussions focus on amino acids linked with citric acid cycle, sulfur amino acids, proline and hydroxyproline, histidine, hydroxyamino acids, urea biosynthesis and related systems, and deamidation. The text then ponders on the biosynthesis of amino acids and related compounds and metabolism of sulfur-containing compounds. Topics include metabolism of methionine, biotin, biological importance of sulfur in animals, interconversions of glutamic acid, ornithine, and prolines, and biosynthesis of the branched-chain amino acids. The publication takes a look at the synthesis of proteins, purines and pyrimidines, and nucleotides and nucleosides, including the components of nucleotides, purine degradation, and incorporation of preformed purine compounds into nucleic acids. The selection is a valuable reference for researchers interested in the metabolism, catabolism, and biosynthesis of amino acids.

  • Physical and Chemical Methods

    Methods in Immunology and Immunochemistry, Vol. 2
    • 1st Edition
    • Curtis A. Williams + 1 more
    • English
    Methods in Immunology: Volume II, Physical and Chemical Methods is a collection of papers dealing with electrophoresis, analytical ultracentrifugation, dialysis, ultrafiltration, cellulose ion exchangers, and chromatographic separation of macromolecules on porous gels. Some papers explain the applications of radioisotopes, optical analysis, and chemical analysis of proteins, carbohydrates, lipids, and nucleic acid. One paper describes the theory of electro-migration. Factors such as electrical charge or frictional coefficients govern the rate of migration of charged particles in an electric field. The differences found in their velocities can be used to separate substances or analyze them. Mobility is a characteristic property of molecules and can also be influenced by the composition of the medium or solution. Dialysis separates solvents too large to diffuse through a barrier from smaller solutes; ultrafiltration (reverse osmosis) forces solvent and solutes up to a certain critical size through the barrier by a high pressure on one side. The book notes that the membrane never becomes plugged in dialysis because of some opposite movement of the solvent. Another paper points out that the significance of radioactive tracers in immunochemistry employed to identify and label macromolecules functioning as antigens and antibodies. The collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunological research.

  • Malaria

    Immunology and Immunization
    • 1st Edition
    • Julius P. Kreier
    • English
    Malaria: Volume 3, Immunology and Immunization is a collection of papers dealing with malaria parasites, the methods for measuring the immunological response to plasmodia, and the vertebrates host's immune response to plasmodia. Some papers discuss immunization against sporozoites, against the exoerythrocytic stages of malaria parasites, against asexual blood-inhabiting stages of plasmodia, as well as gamete immunization in malaria. One paper describes various separation methods to isolate malaria parasites and their constituents. Another paper discusses in detail the theory and practice of methods used in measuring antibody responses which occur during plasmodial infections, including the antibody response against sporozoites, exoerythrocytic forms, and in the different blood stages. Another paper explains the vertebrate host's immune response to plasmodial infection as a homeostatic physiological response changing along with the progression of the disease. The changes in the dynamic cellular cascade are different as the disease progresses causing death, than when these lead to recovery. Another paper enumerates the parameters which determine malarial infectiousness from one individual to another such as the time of onset, duration, intensity of the blood infections, as well as the maturity, longevity, and rate of production of gametocytes. Pharmacologists, general medical practitioners, investigators, and laboratory technicians involved in malarial research will find the collection very useful.

  • Ultrastructure of Protein Fibers

    Papers Presented at a Symposium of the Nineteenth Annual Meeting of the Electron Microscope Society of America, at the Pittsburgh Hilton Hotel, Pittsburgh, Pennsylvania, on August 21, 1961
    • 1st Edition
    • Rubin Borasky
    • English
    Ultrastructure of Protein Fibers covers the papers presented at a symposium of the 19th annual meeting of the Electron Microscope Society of America, held at the Pittsburgh Hilton Hotel in Pittsburgh, Pennsylvania on August 21, 1961. The book focuses on the composition, characteristics, properties, and reactions of protein fibers. The selection first offers information on some essential aspects of protein fiber research, including the elucidation of the fundamental ultra-architecture of proteins in general; identification of the biological role played by fibrous proteins in living organisms; and the use of protein fibers as a natural resource in the form of raw materials and finished products. The manuscript then examines the physical, chemical, and mechanical properties of protein fibers, collagen, and keratins. The text takes a look at some aspects of the ultrastructure of bacterial flagella and feather keratin and fibrous protein systems in muscles. Topics include possible change in myofilament structure underlying the catch function; physiological functions of the fibrous proteins of muscles; organization of the fibrous proteins in muscles; and other functions of fibrous proteins in muscles. The selection is a valuable reference for researchers interested in the ultrastructure of protein fibers.

  • Glutathione

    Proceedings of the Symposium Held at Ridgefield, Connecticut, November, 1953
    • 1st Edition
    • S. Colowick + 2 more
    • English
    Glutathione: A Symposium covers the proceedings of the symposium held in Ridgefield, Connecticut in November 1953. The book focuses on the chemistry, characteristics, reactions, and properties of glutathione (GSH). The selection first offers information on mercaptans and disulfides, reactivity of the sulfhydryl group in GSH and related peptides, and chemistry and properties of GSH. Discussions focus on isolation and occurrence of GSH, properties of GSH, general chemistry of acidity, oxidation, and disulfides, and application to the structure of GSH. The text then examines thiol-thiolester complex formation, methods of GSH assay, and paper chromatography of GSH and its hydrolysis products. The publication takes a look at histochemical experiments on sulfhydryls and disulfides, enzymatic oxidation and reduction of GSH, and biosynthesis of GSH. Topics include synthesis of GSH from the constituent amino acids, enzymatic oxidation of GSH, and methods for demonstrating protein-bound sulfhydryl and disulfide groups in tissues. The selection is a dependable reference for researchers interested in the chemistry, reactions, and properties of glutathione.

  • The Alkaloids

    Chemistry and Physiology
    • 1st Edition
    • R. H. F. Manske
    • English
    The Alkaloids: Chemistry and Physiology, Volume X focuses on the structure of alkaloids. This book discusses the occurrence of glycoalkaloids and alkamines, jerveratrum alkaloids, and erythrophleum alkaloids containing a C-4 carbomethoxy group. The mass spectra of lycopodium alkaloids, alkaloids of the Calabar bean, and benzyltetrahydroisoq... alkaloids with three oxygenated substituents are also elaborated. This publication likewise covers the biogenesis of benzylisoquinoline alkaloids, simple indole bases, biogenesis of the picralima alkaloids, and stereochemistry of the uncarines. Other topics include plants and their contained alkaloids, lycodine and related alkaloids, and a-naphthaphenanthrid... alkaloids. This volume is suitable for chemists and specialists working in the field of alkaloid chemistry.

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