Muscle Stem Cells
- 1st Edition, Volume 158 - April 24, 2024
- Imprint: Academic Press
- Editors: Michael Rudnicki, Jeffrey Dilworth
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 2 3 4 3 5 - 8
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 2 3 4 3 4 - 1
Muscle Stem Cells, Volume 158 in the Current Topics of Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on t… Read more
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Request a sales quoteMuscle Stem Cells, Volume 158 in the Current Topics of Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics surrounding Muscle stem cell dysfunction in rhabdomyosarcoma and muscular dystrophy, Model systems used to study MuSC function, MuSCs in the growth and maintenance of muscle, Molecular regulation of myocyte fusion, A self-made quiescent niche of muscle stem cells, Characterization of the muscle regenerative environment, Role of microenvironment on muscle stem cell function in health, adaptation, and disease, Vascular Niche for Muscle Stem Cells, Regulation of muscle stem cell polarity in health and disease, and more.
Additional chatpers cover Circadian timing of satellite cell function and muscle regeneration, Muscle stem cell activity is regulated by translational control of gene expression, Biomechanical stress in modulating MuSC function, Cross talk between cell types in regenerating muscle, Effects of the immune system on muscle regeneration, Effects of diabetes on MuSC function, and other timely topics.
Additional chatpers cover Circadian timing of satellite cell function and muscle regeneration, Muscle stem cell activity is regulated by translational control of gene expression, Biomechanical stress in modulating MuSC function, Cross talk between cell types in regenerating muscle, Effects of the immune system on muscle regeneration, Effects of diabetes on MuSC function, and other timely topics.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in the Current Topics in Developmental Biology series
- Updated release includes the latest information on the Muscle Stem Cells
Researchers and students
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Preface
- Reference
- Chapter One: Satellite cells in the growth and maintenance of muscle
- Abstract
- 1 Satellite cells
- 2 Postnatal skeletal muscle growth
- 3 Myofiber size and myonuclear content
- 4 Postnatal satellite cell fate and the establishment of quiescence
- 5 Satellite cell contributions in adults
- 6 Conclusion
- References
- Chapter Two: The satellite cell in skeletal muscle: A story of heterogeneity
- Abstract
- 1 General introduction
- 2 Satellite cell heterogeneity
- 3 Symmetric/asymmetric division of MuSC
- 4 Concluding remarks
- References
- Chapter Three: Molecular regulation of myocyte fusion
- Abstract
- 1 Introduction
- 2 Overview of vertebrate myocyte fusion
- 3 Regulation of myocyte fusion by skeletal muscle fusogens
- 4 Cell and tissue morphogenesis
- 5 Exploring myocyte fusion in disease: unique myopathies and emerging therapeutic prospects
- 6 Future directions in myocyte fusion
- Acknowledgments
- References
- Chapter Four: Muscle stem cell dysfunction in rhabdomyosarcoma and muscular dystrophy
- Abstract
- 1 Introduction
- 2 Rhabdomyosarcoma
- 3 Duchenne muscular dystrophy
- 4 Conclusion
- Acknowledgments
- References
- Chapter Five: The extracellular matrix niche of muscle stem cells
- Abstract
- 1 Introduction
- 2 Skeletal muscle stem cell niche
- References
- Chapter Six: Muscle stem cell niche dynamics during muscle homeostasis and regeneration
- Abstract
- 1 Introduction
- 2 Niche cells regulate MuSC functions in muscle regeneration
- 3 Discussion
- Acknowledgments
- References
- Chapter Seven: Role of microenvironment on muscle stem cell function in health, adaptation, and disease
- Abstract
- 1. The skeletal muscle extracellular matrix
- 2 Concluding remarks
- References
- Further reading
- Chapter Eight: Skeletal muscle niche, at the crossroad of cell/cell communications
- Abstract
- 1 Introduction
- 2 The local niche in (regenerating) skeletal muscle
- 3 Remote signals impact the regenerating niche
- 4 Impact of other tissues on skeletal muscle homeostasis
- 5 Concluding remarks
- References
- Chapter Nine: Muscle stem cells as immunomodulator during regeneration
- Abstract
- 1 Introduction
- 2 Cytokine secretion by MuSCs during regeneration
- 3 A subpopulations of MuSCs enriched in immune gene expression
- 4 Senescent MuSCs express inflammatory cytokines
- 5 Summary & future directions
- References
- Chapter Ten: Effects of the immune system on muscle regeneration
- Abstract
- 1 Immune cells in uninjured skeletal muscles
- 2 Immune cells at the early stage of muscle regeneration
- 3 Immune cells at the repairing stage of regeneration
- 4 Conclusion remarks
- Acknowledgements
- References
- Chapter Eleven: Navigating translational control of gene expression in satellite cells
- Abstract
- 1 Introduction
- 2 Nuclear mRNA processing
- 3 Global regulation of protein synthesis in quiescent satellite cells
- 4 Summary
- References
- Chapter Twelve: Decoding the forces that shape muscle stem cell function
- Abstract
- 1 Introduction
- 2 Mechanical forces on SCs during equilibrium, contraction, and stretching
- 3 MuSC mechanosensing machinery
- 4 Myogenic responses to induced mechanical stresses
- 5 Landscape sensation
- 6 MuSCs mechanosensing in aging and disease
- 7 Concluding remarks
- Acknowledgments
- References
- Chapter Thirteen: Circadian timing of satellite cell function and muscle regeneration
- Abstract
- 1 Circadian clocks overview
- 2 Muscle stem cell-autonomous circadian clocks
- 3 Environmental circadian disruption – effects on MuSC function
- 4 Conclusions and future perspectives
- References
- Chapter Fourteen: Epigenetic integration of signaling from the regenerative environment
- Abstract
- 1 Introduction
- 2 Stem cells and tissue regeneration
- 3 The inflammation phase of regeneration
- 4 Inflammation resolution
- 5 Epigenetic regulation of inflammation
- 6 Conclusions
- Acknowledgments
- References
- Chapter Fifteen: Chromatin organization of muscle stem cell
- Abstract
- 1 The multi-layered organization of chromatin in the cell nucleus
- 2 Chromatin dynamics in muscle stem cell activation: a focus on transcriptional factors
- 3 Histone remodeling in muscle stem cell activation and differentiation
- 4 Chromatin accessibility assay to follow muscle stem cell activation
- 5 Large scale dynamics in MuSC
- 6 Pathological chromatin remodeling in muscular aging
- 7 Conclusion
- Acknowledgments
- References
- Chapter Sixteen: 3D organization of enhancers in MuSCs
- Abstract
- 1 Introduction
- 2 Properties, identification and functional testing of enhancer
- 3 3D chromatin organization
- 4 3D remodeling of enhancers during MuSC specification: The role of PAX TF
- 5 3D rewiring of enhancers during MuSC lineage progression
- 6 3D re-organization of enhancers during MuSC aging
- 7 Concluding remarks
- Acknowledgments
- References
- Chapter Seventeen: Long non-coding RNAs and their role in muscle regeneration
- Abstract
- 1 Introduction
- 2 Muscle stem cells and muscle regeneration
- 3 LncRNAs
- 4 LncRNAs in muscle
- 5 CircRNAs
- 6 CircRNAs in muscle
- References
- Edition: 1
- Volume: 158
- Published: April 24, 2024
- No. of pages (Hardback): 486
- No. of pages (eBook): 362
- Imprint: Academic Press
- Language: English
- Hardback ISBN: 9780128234358
- eBook ISBN: 9780128234341
JD
Jeffrey Dilworth
Affiliations and expertise
University of EssexRead Muscle Stem Cells on ScienceDirect