Carbon-Based Nanomaterials in Biosystems

Biophysical Interface at Lower Dimensions

1st Edition - April 20, 2024
Editors: Kunal Biswas, Yugal Kishore Mohanta, Tapan Kumar Mohanta, Muthupandian Saravanan
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 5 0 8 - 6
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 5 0 9 - 3

Carbon-Based Nanomaterials in Biosystems: Biophysical interface at Lower Dimensions provides a thoroughly comprehensive overview of all major aspects of carbon-based nanomater… Read more

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Carbon-Based Nanomaterials in Biosystems: Biophysical interface at Lower Dimensions provides a thoroughly comprehensive overview of all major aspects of carbon-based nanomaterials, their biophysical response, and biotechnological applications. The book articulates the underlying physics, chemistry, and the basic phenomenon of the broad-range carbon-based nanomaterials (CNMs) with biological systems, particularly the interface analysis. Organized in six sections, it discusses state-of art technological interventions of carbon-based nanomaterials and their application in biomedical sectors in healthcare, food sciences, and technology. The book also highlights the carrying capacity of different CNMs in payload efficiency mechanisms in various biomedical fields. The theranostic efficiency and the safety of various forms of CNMs is assessed. This book will be a helpful resource to those specializing in the areas of nanomedicine, bionanomaterials, and nanotechnology applications.

Cover image
Title page
Table of Contents
Copyright
Dedication
List of contributors
Preface
Important features of the book are enumerated
Acknowledgment
Introduction
Section 1: Carbon-based Nanomaterials: Fabrication, Manufacture, and Underlying Physicochemical Properties
Section 2: Carbon-based Nanomaterials in Food Industry
Section 3: Role of Carbon-based Nanomaterials in Agriculture
Section 4: Role of Carbon-based Nanomaterials in Biomedicine
Section 5: Carbon Nanomaterials–based Biosensors/Devices for Food, Agriculture, and Biomedicines
Section 6: Toxicity Assessment of Different Forms of Carbon-based Nanomaterials (Safety, Health Evaluation [SHE])
Part 1: Carbon-based nanomaterials: fabrication, manufacture, and underlying physicochemical properties
Chapter 1. Introduction to the carbon-based nanomaterials and its unique electrochemical and physicochemical properties
Abstract
1.1 Introduction
1.2 Carbon-based nanomaterials
1.3 Dimensionality
1.4 Physical properties of carbon nanomaterials
1.5 Chemical and electrochemical properties of carbon nanomaterials
1.6 Conclusion
Acknowledgments
References
Chapter 2. Synthesis, characterization, and applications of carbon nanomaterials from a nanobiotechnological perspective
Abstract
2.1 Introduction
2.2 Conclusion and future research work
References
Chapter 3. Green carbon nanomaterials and their application in food, agriculture, and biomedicine
Abstract
3.1 Introduction
3.2 Synthesis of various carbon nanomaterials
3.3 Green synthesis of carbon nanomaterials
3.4 Applications of green nanomaterials
3.5 Conclusion
References
Chapter 4. Recent trends in the “bottom-up” and “top down” techniques in the synthesis and fabrication of myriad carbonaceous nanomaterials
Abstract
4.1 Introduction
4.2 Carbon nanomaterials
4.3 Nanotechnology-based system
4.4 Development of myriad carbonaceous nanomaterials
4.5 Synthetic methods for the myriad carbonaceous nanomaterials
4.6 Characterization tools
4.7 Applications of carbon nanoparticles
4.8 Conclusion
Acknowledgments
References
Part 2: Carbon-based nanomaterials in food industry
Chapter 5. Implications of caged molecular structure of buckminster fullerenes in food sciences and industry applications
Abstract
5.1 Introduction
5.2 Fullerenes: basic characteristics
5.3 Applications of fullerenes in food science and safety
5.4 Biomedical applications of fullerenes
5.5 Consumer exposure
5.6 Fullerenes as a human health hazard
5.7 Acute and repeated dose toxicity
5.8 Biological mechanisms and target organ toxicity
5.9 Conclusion
Acknowledgment
References
Chapter 6. Uncovering the unique attributes of 2D graphene-based nanomaterials in food safety and practices
Abstract
6.1 Introduction
6.2 Design and synthesis of 2D graphene nanomaterial
6.3 Mechanical and chemical properties of graphene nanomaterials
6.4 Graphene-based nanocomposites applied to food processing (graphene, graphene oxide, and reduced graphene oxide)
6.5 Conclusion
References
Chapter 7. Role of different types of carbon nanotubes in food sciences and food sensing applications
Abstract
7.1 Introduction
7.2 Classification of carbon nanotubes and their properties
7.3 Role of carbon nanotubes in food science
7.4 Role of carbon nanotubes in food sensing applications
7.5 Carbon nanotubes: current scenario and prospects
References
Part 3: Role of carbon-based nanomaterials in agriculture
Chapter 8. Role of carbonaceous fullerene materials in crop improvement and targeted pesticide management
Abstract
8.1 Introduction
8.2 Historical background
8.3 Classification of carbonaceous fullerene
8.4 Fabrication of carbonaceous fullerene materials
8.5 Properties of carbonaceous fullerene-based materials
8.6 Role of carbonaceous fullerene-based materials in crop improvement
8.7 Role of carbonaceous fullerene-based materials in pesticide management
8.8 Conclusions
References
Chapter 9. Unconventional role of 2D graphene-based nanomaterials and their composites in crop improvement and novel fertilizers application
Abstract
9.1 Introduction
9.2 Fabrication of GBNs
9.3 Structure and properties of graphene-based nanomaterials
9.4 Functional modification
9.5 Opportunities of graphene-based nanomaterials on crop improvement
9.6 Graphene-based nanomaterials as smart fertilizer
9.7 Loading graphene-based nanomaterials with agrochemicals
9.8 Recent research on graphene-based nanomaterials as agrochemical delivery system
9.9 Environmental impact of graphene-based nanomaterials
9.10 Accumulation and behavior of graphene-based nanomaterials in plants
9.11 Conclusion
References
Chapter 10. Exploring the different anisotropic chirality-based carbon nanotubes and their organic/inorganic composites in rotten crop toxin sensing, prevention, and shelf-life expansion
Abstract
10.1 Introduction
10.2 Different types of carbon nanotubes and their properties
10.3 Anisotropic behavior (different properties in different directions) of different CNTs emanated from the different chirality-based architecture of CNTs
10.4 CNTs in the detection of agricultural crop toxins
10.5 Inorganic and organic composite CNTs applications
10.6 Conclusion and prospects
10.7 Challenges in the CNT-based food toxin detection and associated agricultural management
Acknowledgment
Conflict of interest
References
Part 4: Role of carbon-based nanomaterials in biomedicine
Chapter 11. Evaluation of zero-dimensional buckyball-based fullerene molecules in targeted drug delivery applications in dreaded diseases
Abstract
11.1 Introduction to nanostructured materials
11.2 Fullerenes
11.3 Medicinal applications of fullerenes
11.4 Drug delivery applications in dreaded diseases
11.5 Challenges and future perspective
11.6 Conclusions
References
Chapter 12. Role and development of unique 2-dimensional graphene-based nanomaterials in antimicrobial and molecular theranostics applications
Abstract
12.1 Introduction
12.2 Graphene nanomaterials for antibacterial applications
12.3 Graphene-based nanomaterials for molecular theranostics applications
12.4 Summary and future scope
References
Chapter 13. Recent trends and practices of bio-functionalized carbon nanotubes in bioimaging and biosensing applications in biomedical sectors
Abstract
13.1 Introduction
13.2 Structure and properties
13.3 CNT biosensors for disease detection
13.4 Near-infrared photoluminescence CNTs
13.5 Raman scattering of CNTs
13.6 Magnetic resonance imaging using CNTs
13.7 Ultrasonography
13.8 Photoacoustic imaging
13.9 Positron emission tomography
13.10 Fluorescence imaging
13.11 X-ray/computed tomography imaging using CNTs
13.12 Applications of CNTs
13.13 Prospects and challenges
Author contributions
References
Chapter 14. Combating “diseases,” employing different forms of carbonaceous nanomaterials via “theranostic” applications in clinical and biomedical sectors
Abstract
14.1 Introduction
14.2 Carbon as nanomaterial
14.3 Different imaging modalities of CNMs
14.4 Multipurpose photodynamic CNM therapeutic methods
14.5 Applications of carbon-based materials in photodynamic and photothermal therapies
14.6 Merits
14.7 Demerits
References
Part 5: Carbon nanomaterial–based biosensors/devices for food, agriculture, and biomedicines
Chapter 15. Potentialities of zero-dimensional fullerenes in designing biosensing modalities in crop, food toxin, and biomedicines
Abstract
15.1 Nanotechnology
15.2 Classification of nanoparticles
15.3 Application of nanoparticles
15.4 Application of nanoparticles in various sectors
15.5 Zero-dimensional nanoparticles
15.6 Other types of zero-dimensional nanoparticles
15.7 Application of zero-dimensional nanoparticles in biosensing
15.8 Fullerenes
15.9 Applications of fullerenes
Author contributions
Funding
References
Chapter 16. Role of fabricated anisotropic graphene and nanotube-based electrochemical sensors for food, crop damage surveillance, and management
Abstract
16.1 Introduction
16.2 Primarily carbon-based nanomaterials
16.3 Dimensionality
16.4 Types of nanomaterial-based electrochemical sensors
16.5 Chemical and electrochemical properties of carbon nanomaterials
16.6 Advantages and limitations of functionalized nanomaterial-based electrochemical sensors
16.7 Conclusion
Acknowledgments
References
Chapter 17. Unveiling the potential activities of myriad carbonaceous nanomaterials in scaling and fabrication of miniaturized, sensitive, and economical medical diagnostic kits
Abstract
17.1 Introduction
17.2 Carbonaceous nanomaterials
17.3 Applications of carbonaceous nanomaterials for medical diagnostic kits
17.4 Challenges and prospects for further applications
17.5 Conclusions
References
Chapter 18. Role of different approaches of functionalization over carbonaceous nanomaterials in designing different sensor devices in food crop and biomedical sectors
Abstract
18.1 Introduction
18.2 Surface functionalization
18.3 Role of functionalized CNM sensor devices
18.4 Conclusions
Acknowledgments
References
Part 6: Toxicity assessment of different forms of carbonbased nanomaterials: safety, health evaluation (SHE)
Chapter 19. Toxicological analysis of carbon-based nanomaterials in food industry applications
Abstract
19.1 Introduction
19.2 Significance of carbon nanomaterials in food industry
19.3 Toxicity investigations of carbon nanomaterials
19.4 Conclusions
References
Chapter 20. Risks associated with the clinical trials of carbon-based nanomaterials in agricultural domains
Abstract
20.1 Introduction
20.2 Classification of carbon-based nanomaterials
20.3 Synthesis of carbon-based nanomaterials
20.4 Potential applications of carbon nanomaterials
20.5 Impact of carbon-based nanomaterials on agricultural domains
20.6 Future scope of study
20.7 Conclusion
References
Chapter 21. Safety matters pertaining to carbon-based nanomaterials in drug designing for targeted drug delivery in biomedical sciences
Abstract
21.1 Introduction
21.2 Types of carbon nanomaterials
21.3 Properties of carbon nanomaterials
21.4 Applications of carbon nanomaterials in treating various diseases
21.5 Toxicity analysis of carbon-based nanomaterials
21.6 Safety measures to be implemented for reducing toxicity of NPs
21.7 Nanomaterials in medicine: future toxicological needs
21.8 Conclusion
References
Index

Kunal Biswas

Dr. Kunal Biswas is currently a Scientist at the Centre for Nanoscience & Nanotechnology at the Sathyabama Institute of Science and Technology in Chennai. He received his Master’s degree in Nanoscience and Technology from the Department of Physics, Tezpur Central University, Assam, India and his PhD in Nanobiotechnology from Maulana Abul Kalam Azad University of Technology, West Benga. He has more than 8 years of research experience in Nano-Bio sciences. He has been working in the field of carbonaceous nanomaterials and its widespread applications ranging from material sciences to biotechnology. His area of research is nano-biotechnology which include material engineering, nano-bio sensors, sensor fabrication, nanotechnology, synthetic biology, the nano-bio interface, and application of machine learning (ml) and deep learning (dl) techniques in materials science and engineering. He has contributed book chapters and published in peer-reviewed SCI-indexed journals like Frontiers in Microbiology, Molecules, Nanobiotechnology, and Materials Focus.

Affiliations and expertise

Scientist C, Centre for Nanoscience & Nanotechnology, International Research Centre, Sathyabama Institute of Science and Technology

Yugal Kishore Mohanta

Dr. Yugal Kishore Mohanta is an Assistant Professor in the Department of Applied Biology, School of Biological Sciences at the University of Science and Technology Meghalaya (USTM). His current research is green nanoparticles and its potential application in food and biomedicine. He earned his PhD in Life Sciences from North Orissa University, Baripada. He has also successfully completed the BCIL industrial training programme on Plant Tissue Culture sponsored by the Department of Biotechnology. Among other academic/research achievements, he was awarded as visiting research scholar at Department of Biology, KU Leuven, Belgium sponsored by KU Leuven. He has more than ten years research experience on natural products chemistry and nanobiotechnology. He has published in peer-reviewed SCI-indexed journals like BMC Plant Biology, Frontiers in Microbiology, Molecules, Frontiers on Plant science, Frontiers in molecular biosciences Nanobiotechnology, and Materials Focus. He has also contributed 11 book chapters and edited a book.

Affiliations and expertise

Assistant Professor, Department of Applied Biology, School of Biological Sciences, University of Science and Technology Meghalaya (USTM)

Tapan Kumar Mohanta

Dr. Tapan Kumar Mohanta is currently a Research Assistant Professor at the University of Nizwa in Oman. Before joining the University of Nizwa, Dr. Mohanta was working as a Research Professor at Yeungnam University, Gyeongsan, South Korea. Dr. Mohanta also worked as a postdoctoral research associate at the G.B. Pant University of Agriculture and Technology, Pant Nagar, India and the National Institute of Plant Genome Research, New Delhi, India. To his credit, Dr. Mohanta has more than 70 SCI/SCI-E indexed peer-reviewed research publications in Q1, Q2, and Q3 journals in the field of plant genomics, molecular biology, metabolomics, and nanomaterial science. In addition, Dr. Mohanta has contributed several book chapters and other research publications as well. Dr. Mohanta earned an MS degree in Bioinformatics and a PhD degree from the University of Turin, Italy and an MSc in Biotechnology degree from North Orissa University, India.

Affiliations and expertise

Research Assistant Professor, Natural and Medical Sciences Research Centre, University of Nizwa, Oman

Muthupandian Saravanan

Dr. Muthupandian Saravanan is currently a Professor in the Department of Pharmacology at Saveetha University, SIMATS, Chennai, India. He has a degree in Microbiology from Madurai Kamaraj University and a Doctorate with Specialization in Medical Microbiology and Nanomedicine from Sathyabama University, India. As a Post-Doctoral Researcher at the Hebrew University of Jerusalem, he studied nano-biomaterials and their biomedical applications. He later worked as Associate Professor, under the United Nation Development Program in Department of Medical Microbiology and Immunology at Mekelle University in Ethiopia. He has published papers in high impact journals such as the Lancet and Nature. He has participated in more than 75 national and international conferences and reviewed of more than 100 international peer-reviewed journals. He has served as guest editor/ co-editor for reputed PubMed and Scopus indexed journals. He has received many fellowships and awards, notably the IET- Nanobiotechnology premium Awards in 2019 and 2020.

Affiliations and expertise

Professor, AMR and Nanotherapeutics Lab, Department of Pharmacology Saveetha Institute of Medical and Technical Sciences (SIMATS)