Skip to main content
Elsevier
View Cart
openUserAccount

Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

BooksJournals
151-160 of 389 results in All results

The Scientific Basis of Drug Therapy in Psychiatry

  • 1st Edition
  • October 22, 2013
  • John Marks + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 5 4 - 5
The Scientific Basis of Drug Therapy in Psychiatry is a collection of papers that covers the therapeutic effects and the mode of action of the various psychotropic drugs. The materials in the title are organized thematically based on the topic they tackle. The text first covers the articles on the basic concepts, such as anatomy and physiology of the emotions and their relation to psychoactive drugs, as well as the methods of assessment of psychological effects of drugs. The next three chapters cover the concerns with the psychotropic drugs that include clinical use, mode of actions, and pharmacology. The remaining paper talks about some of the considerations that need to be taken when administering psychotropic drugs. The book will be of great use to researchers and practitioners in behavioral science related disciplines, such as psychology, psychiatry, and neurology. Pharmacologists and medicinal chemists will also benefit from the text.

The Toxicology of Radioactive Substances

  • 1st Edition
  • October 22, 2013
  • A. A. Letavet + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 7 0 - 3
The Toxicology of Radioactive Substances, Volume 3: Iron-59 deals with the experimental results of tests conducted at the Radiotoxicology Laboratory of the Institute of Occupational Hygiene and Disease, Academy of Medical Sciences, U.S.S.R. The book focuses on studies made on iron-59, which is widely used in science and technology, such as in the metal industry and in the research of hemoglobin metabolism in the bone marrow and red cells. Other studies show, however, that there is a long-term detrimental effect of intake of iron-59. The text then gives a brief outline of the physical, chemical, and biological properties of iron. Research also shows that the body's reaction to radioactive substances depends on how these are transmitted to the body and on their physicochemical properties. The effect of prolonged administration of radioactive iron on the electrical activity of the cerebral cortex of animals is analyzed, of which, possibly, the nervous system is most affected. The book notes also the changes in the red blood cells during chronic administration of iron-59 in small doses, wherein the hemoglobin levels increased temporarily. Studies of prolonged exposure to radioactive isotopes during pregnancy of the test animals show that there are significant changes in erythropoiesis, associated with iron deficiency. In another study, the prolonged internal administration of radioactive substances showed phasic changes in the height of electrocardiographic waves of the test animals. The text is suitable for physicists, nuclear scientists, doctors of toxicology, and researchers in nuclear medicine.

Thorium-232 and Uranium-238

  • 1st Edition
  • October 22, 2013
  • A. A. Letavet + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 3 0 1 - 8
The Toxicology of Radioactive Substances, Volume 4: Thorium-232 and Uranium-238 deals with the toxic properties of two radioactive elements, thorium-232 and uranium-238, as well as their soluble and insoluble compounds. Emphasis is placed on their biological effects and the late sequelae of their administration, especially in the case of insoluble compounds. Some of the results of laboratory studies on the acute and chronic effects of the very poorly soluble uranium compound U3O8 are presented. This volume is comprised of 12 chapters and opens with an overview of certain aspects of the toxicology of insoluble compounds of thorium-232 and uranium-238, followed by a discussion on the comparative toxicity of soluble and insoluble compounds of thorium-232. Subsequent chapters explore the absorption, distribution, and excretion of certain soluble compounds of natural thorium; the behavior of thorium dioxide in rats after intratracheal and intraperitoneal administration; the effect of thorium dioxide on the peripheral blood of rats; and photometric determination of low amounts of thorium in biological materials. Changes in the peripheral blood following chronic and acute poisoning with U308 are also considered. This book will be of interest to chemists and toxicologists.

The Toxicology of Radioactive Substances

  • 1st Edition
  • October 22, 2013
  • A. A. Letavet + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 3 0 5 - 6
The Toxicology of Radioactive Substances, Volume 5: Zinc-65 deals with the toxic properties of the radioisotope zinc-65 as well as its biological effects. Emphasis is placed on the role of stable zinc in the reaction of the body to the administration of zinc-65. Some of the results of laboratory studies on the toxic effects of zinc-65 on animals, primarily rabbits, are presented. This volume is comprised of 18 chapters and opens with an overview of certain aspects of the toxicology of radioactive zinc-65, followed by a discussion on the behavior of zinc-65 in the rat body. Subsequent chapters explore the distribution of zinc-65 in the body of rabbits following chronic oral administration; bioelectrical activity of the cerebral cortex in rabbits in conditions of prolonged administration of radioactive zinc; the effect of prolonged internal irradiation with G5ZnCl2 on the functional state of the rabbit heart; and aspects of hemopoiesis following chronic intake of radiozinc. Morphological changes in experimental animals following chronic exposure to radioactive zinc are also considered. This book will be of interest to chemists and toxicologists.

Drugs and Youth: The Challenge of Today

  • 1st Edition
  • October 22, 2013
  • Ernest Harms
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 7 0 1 - 3
Drugs and Youth: The Challenge of Today mainly focuses on the issue of drug addiction in youth and on how to bring this issue to the knowledge of the concerned sectors. This text first discusses the effects on the fetus and newborn of drug abuse in pregnancy. This book then explains the major drugs adolescents and young adults take, including solvents wherein a survey related to this is also presented in this publication. The effects of these drugs, such as physical and mental illnesses, are also tackled. This text also looks into the approaches in the treatment of adolescent drug addicts, including the withdrawal syndrome, group therapy, and psychotherapy. This book concludes by explaining the religious problematic and aftercare problems with the juvenile drug addict. This publication will be invaluable to medical practitioners, sociologists, social workers, ministers, and students doing a research on drug addiction in youth.

Drugs and Driving

  • 1st Edition
  • October 22, 2013
  • Herbert Moskowitz
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 7 8 4 - 6
Drugs and Driving is a compendium of papers from a symposium of the same title presented at the U.S. Transportation Research Board. This collection reviews the effects of five classes of drugs on driving (amphetamines, tranquilizers, barbiturates, narcotics, cannabis), the other studies being made on drugs and driving, as well as some countermeasure programs against drunk driving. The papers report that amphetamines can induce risky driving behavior, tranquilizers can increase traffic accident risks, barbiturates can degrade driving skills especially when the drug is combined with alcohol, while marijuana use can impair important driving skills. Another paper evaluates drug use and driving risk among high school students in Toronto: results show that the total effect of infrequent use of drugs on accidents is small compared to alcohol use. A study of out-patients in Finland notes that the combined used of alcohol and drugs tend to increase accident frequency. One paper refutes that Alcohol Safety Action Programs in the United States are ineffective. This collection can be helpful for sociologist, psychologists, psychiatrists, traffic safety officers, and heads of urban safety and traffic divisions.

Pharmacology of Central Synapses

  • 1st Edition
  • October 22, 2013
  • V. V. Zakusov
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 6 7 3 - 7
Pharmacology of Central Synapses deals with the pharmacology of the central nervous system and the mode of action of neurotropic drugs based on their influence on synaptic transmission. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological, and biochemical findings, form the conceptual basis of this book. Comprised of eight chapters, this book examines the effect of neurotropic drugs on the synaptic transmission in reflex, projection, and association (commissural) tracts. The specific effects of various narcotics, neuroleptics, tranquillizers, analgesics, antidepressants, and stimulants on synaptic transmission in various structures of the central nervous system and at its different levels are described. This text also considers the differences in the sensitivity to such drugs of various synapses and their influence on the selectivity of drug action. This book explains the influence of neurotropic drugs on such aspects of nervous activity as impulse summation, after-discharge and functional lability, central inhibition, and the neurochemical mechanisms, particularly those involving monoaminergic, cholinergic, serotoninergic, and GABA-ergic components of synaptic transmission. The final chapter focuses on the effect of psychotropic drugs on behavior. This book will be helpful to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

The Psychopharmacology of Hallucinogens

  • 1st Edition
  • October 22, 2013
  • Richard C. Stillman + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 6 0 6 - 5
The Psychopharmacology of Hallucinogens focuses on the properties, compositions, functions, transformations, and reactions of hallucinogens. The selection first offers information on the biosynthesis and action of hallucinogens in mammals; role of biogenic amines in the actions of monomethoxy-amphetamines; and molecular mechanism of action of hallucinogens. The book then takes a look at the molecular determinants for interaction with the LSD receptor, including biological studies, molecular reactivity, and summation of the molecular polarization complexes. The text examines the progress on the development of a receptor model for hallucinogenic amphetamines; characterization of psychotomimetics; physical identification of hallucinogenic compounds; and aspects of the pharmacology of phencyclidine. The book also underscores the effects of LSD, mescaline, and DMT, including effects on humans, proposed model, and effects of monoamine manipulations. The text also presents analysis of hallucinogens by Pavlovian conditioning, behavioral measures of hallucinogenic behavior, and drug model of hallucinosis. The selection is a dependable reference for readers interested in the study of hallucinogens.

Evaluating Alcohol and Drug Abuse Treatment Effectiveness

  • 1st Edition
  • October 22, 2013
  • Linda Carter Sobell + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 8 4 8 - 5
Evaluating Alcohol and Drug Abuse Treatment Effectiveness: Recent Advances is a collection of papers that covers the advancement in rehabilitation of individuals with a history of substance abuse. The title aims to find ways in identifying the treatment that best fits a specific patient. The text first provides a historical account of alcohol and drug treatment outcome research. Next, the selection considers the use of multiple measures of life health to assess alcohol treatment. Chapter 3 deals with the behavioral assessment and treatment evaluation of narcotic addiction, while Chapter 4 talks about the evaluation of behavioral and traditional treatment of alcoholics. The fifth chapter tackles the contingency contracting with drug abusers, and the sixth chapter covers the development of a prototype for the evaluation of alcohol treatment. The text also details the problems in alcohol treatment along with the improvement of confidence in treatment of substance abuse. The book will be of great use to behavioral scientists, social workers, and mental health specialists.

Ions-Cyclic Nucleotides-Cholinergy

  • 1st Edition
  • October 22, 2013
  • J.C. Stoclet
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 8 5 7 - 7
Advances in Pharmacology and Therapeutics, Volume 3: Ions – Cyclic Nucleotides – Cholinergy covers the proceedings of the Seventh International Congress of Pharmacology, held in Paris in 1978. This book mainly focuses on studying ions, cyclic nucleotides, and cholinergy. Specifically, this text discusses the pharmacology of calcium homeostasis and presents lectures given in the symposium. The role of cyclic nucleotides in the regulation of muscular tissue functions and the evaluation of cyclic AMP and cyclic GMP are also looked into. This text presents in its latter part papers on chemical structure and cholinergic activity. This volume will be valuable to students and experts in the field of pharmacology, therapeutics, and related fields.

Related subjects

Analytic forensic toxicology

Carcinogenic and genetic toxicology

Cardiovascular toxicology

Metal toxicology

Neurobehavioral toxicology

Occupational toxicology

Pesticide toxicology

Plant and animal toxins

Regulatory toxicology

Renal toxicology

Reproductive endocrine toxicology

Respiratory toxicology

Risk assessment

Solvent and vapor toxicology

Toxicology environmental

Toxicology general

Toxicology principles

Toxicology testing and evaluation