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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • TRP Channels as Therapeutic Targets

      • 2nd Edition
      • August 22, 2024
      • Arpad Szallasi
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 6 5 3 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 5 4 7
      TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

    • The Diagnosis and Treatment of Protozoan Diseases

      • 1st Edition
      • May 29, 2024
      • Tarun Kumar Bhatt
      • English
      • Paperback
        9 7 8 0 4 4 3 1 9 1 6 1 9
      • eBook
        9 7 8 0 4 4 3 1 5 2 4 5 0
      The Diagnosis and Treatment of Protozoan Diseases discusses major protozoan diseases such as Malaria, Leishmaniasis, etc., including other clinically minor protozoan diseases. This book provides all essential information to professional researchers and medical personnel about the disease, causative organism, and their lifecycle, diagnostics, and treatments, including drugs and vaccine, resistance, and key points of future research. Infectious diseases are accountable for millions of deaths every year throughout the globe. Among them, significant contributors are protozoan parasites.Despite the many research group working on the various protozoan diseases, there are still major gaps to fill. The authors of this book have critically reviewed all the aspects of major protozoan diseases, their diagnostics, and treatments, including resistance.

    • Exosome Communication

      • 1st Edition
      • November 15, 2024
      • Dalapathi Gugulothu + 3 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 9 0 5 2 7
      • eBook
        9 7 8 0 4 4 3 2 9 0 5 3 4
      Exosome Communication: Advances in Research and Therapeutics for Health and Disease serves as a crucial reference for pharmaceutical scientists, focusing on the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering significant advantages over traditional drug delivery systems such as liposomes and polymeric nanoparticles, due to their nonimmunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for isolation and characterization. This book also addresses critical considerations like quality control, heterogeneity reduction, regulatory and ethical aspects, clinical trials, and scale-up manufacturing.

    • Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19

      • 1st Edition
      • November 6, 2024
      • Nabeelah Bibi Sadeer + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 7 5 7 5
      • eBook
        9 7 8 0 4 4 3 1 8 7 5 8 2
      Traditional Medicines and Natural Products as Preventive and Therapeutic Agents Against COVID-19: A Promising Response to the Global Unprecedented Pandemic presents comprehensive coverage of the pharmacological effects of natural products on the prevention and treatment of COVID-19. Sections provide traditional medicine approaches and their potential to prevent and treat COVID-19 infection, including traditional Chinese, Ayurvedic, Persian, and Kampo medicine, alongside an overview of nutritional regimens and their therapeutic potential. Other sections cover natural molecules such as flavonoids, saponins, coumarins, alkaloids, terpenes, polysaccharides, and several microbial natural products of relevant action against viruses. Final chapters cover nanotherapeutic approaches.This is a valuable resource for researchers and academics in the fields of herbal medicine, pharmacology, pharmacognosy and for professionals in the pharmaceutical industries and anyone interested in natural products and their application for therapeutic purposes.

    • Therapeutic Drug Monitoring

      • 2nd Edition
      • April 26, 2024
      • Amitava Dasgupta
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 6 4 9 3
      • eBook
        9 7 8 0 4 4 3 1 8 6 5 0 9
      Therapeutic Drug Monitoring: Newer Drugs and Biomarkers, Second Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated.This book is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book.

    • Quinone-Based Compounds in Drug Discovery

      • 1st Edition
      • October 25, 2024
      • Umar Ali Dar + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 2 4 1 2 6 0
      • eBook
        9 7 8 0 4 4 3 2 4 1 2 5 3
      Quinone-Based Compounds in Drug Discovery: Trends and Applications provides a comprehensive and up-to-date overview of the latest advances in the field of drug discovery using quinone-based materials. The book covers various aspects of quinone-based materials such as their synthesis, characterization, and applications in drug discovery, consolidating current research. It introduces quinones in the pharmacology context and then describes current developments in drugs for key diseases and conditions. Final chapters deal with the regulatory and commercial framework to take quinone-based drugs to the market.This book will benefit a wide range of readers, including researchers, scientists, and graduate students in the field of drug discovery. Chemists and biochemists will also benefit from the contents of this book.

    • Pharmacovigilance

      • 2nd Edition
      • November 20, 2024
      • Thao Doan + 4 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 1 8 8 1 4
      • eBook
        9 7 8 0 4 4 3 1 1 9 3 0 9
      • eBook
        9 7 8 0 4 4 3 1 1 9 3 1 6
      Written by multidisciplinary experts in the fields of pharmaceutical and patient safety, Pharmacovigilance: A Practical Approach, Second Edition, provides a succinct, easy-to-digest overview of an increasingly critical area of medical safety. From cover to cover, this concise resource offers essential information for physicians and other health care professionals, clinical researchers, and regulators who need a comprehensive, up-to-date source of information on the principles and practice of pharmacovigilance.

    • mRNA Therapeutics

      • 1st Edition
      • September 9, 2024
      • Anya Hillery
      • English
      • Paperback
        9 7 8 0 4 4 3 2 8 9 3 4 7
      • eBook
        9 7 8 0 4 4 3 2 8 9 3 5 4
      mRNA Therapeutics: Foundations, Innovations and Clinical Applications aims to provide a comprehensive text that covers all aspects of mRNA therapeutics, from the foundational science that underpins this disruptive new drug class, through the scientific and technological breakthroughs crucial for therapeutic success, to the current clinical applications and the innovative advances driving future directions. The book begins with foundational knowledge covering mRNA biology, the immune system, and vaccines. The second section addresses the major challenges associated with mRNA as a therapeutic modality, and the molecular engineering innovations and delivery technologies that have allowed these hurdles to be largely overcome. The third section describes the current and future clinical applications of mRNA therapeutics that are transforming, or are poised to transform, medicine and health. This includes the use of mRNA vaccines for COVID-19 and other infectious diseases, as well as mRNA's role in revolutionizing cancer immunotherapy, covering immunostimulants, cancer vaccines including personalized neoantigen vaccines, and CAR T cell technologies. Additional chapters describe the use of mRNA therapeutics for protein replacement therapy and gene-editing, as well as newer mRNA constructs, including self-amplifying mRNA. The final section addresses the safety and regulatory considerations of mRNA therapeutics, along with broader cultural issues including vaccine hesitancy, global vaccine inequality, and pandemic preparedness. Currently, mRNA texts either provide personal accounts from key players involved in COVID-19 vaccine development, with limited scientific depth, or focus on highly specialized, more esoteric applications of mRNA in advanced molecular biology. This book aims to bridge this gap by providing a scientifically rigorous and wide-ranging exploration of mRNA's role in therapeutics. This pioneering textbook serves as a vital addition to the academic canon, providing an essential tool for the current and next generation of students, scientists, researchers and professionals in a wide variety of related disciplines including molecular biology, biomedical engineering, pharmaceutical science, oncology, and the health sciences.

    • Pharmacology in Drug Discovery and Development

      • 3rd Edition
      • May 21, 2024
      • Terry P. Kenakin
      • English
      • Paperback
        9 7 8 0 4 4 3 1 4 1 2 4 9
      • eBook
        9 7 8 0 4 4 3 1 4 1 2 5 6
      Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

    • Advancement of Phenolic Acids in Drug Discovery

      • 1st Edition
      • June 19, 2024
      • Naresh Kumar + 2 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 8 5 3 8 0
      • eBook
        9 7 8 0 4 4 3 1 8 5 3 9 7
      Advancement of Phenolic Acids in Drug Discovery: Fundamental and Applications offers comprehensive coverage of the ADMET profiles of phenolic acids, their extraction method and prospects for drug design and development. Chapters overview phenolic acids and their characterization, discuss the role of phenolic acids in plant systems, present sources and detailed extraction methods of phenolic acids, and cover phenolic acid mechanisms of action as it relates to several key diseases and health conditions, including their role as antioxidant agents, anti-inflammatory and analgesic drugs, anti-microbial drugs, anti-viral drugs, anti-cancer drugs, diabetes and metabolic dysfunctions, neurological disorders, cardiovascular diseases. The book’s final chapters cover nanoscience aspects of phenolic acids, biomedical applications, and concludes with challenges and opportunities presented by phenolic acids. This is the ideal reference for researchers in the fields of drug development, both in academia and corporate settings. Researchers of related areas like food science and medicinal chemistry will also benefit from this in-depth profiling of therapeutical properties of phenolic acids.

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